Transgenic Swine, Methods Of Making And Uses Thereof, And Methods Of Making Human Immune System Mice

AU2026206241A1Pending Publication Date: 2026-08-06THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
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Patent Information

Authority / Receiving Office
AU · AU
Patent Type
Applications
Current Assignee / Owner
THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
Filing Date
2026-07-20
Publication Date
2026-08-06

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Abstract

The present disclosure provides for transgenic swine, comprising one or more nucleotide sequences encoding one or more HLA I polypeptides and / or one or more HLA II polypeptides inserted into one or more native SLA loci of the swine genome, methods of making and methods of using. The present disclosure also provides for improved methods of making human immune system mice. 20 26 20 62 41 20 J ul 2 02 6 2 0 2 6 2 0 2 6 2 0 6 2 4 1 2 0 J u l
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