9-aminomethyl minocycline compounds and uses thereof

Abstract

Methods and compositions for using a tetracycline compound to treat bacterial infections are described. In one embodiment, for example, the invention provides a method of treating a subject for an infection, comprising administering to said subject an effective amount of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, such that 5 said subject is treated, wherein the 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline is administered orally at a dose of about 450 mg per day for two consecutive days, then at a dose of about 300 mg per day for 5 or more days. 5 - 90 - 20 26 20 80 00 22 J ul 2 02 6 A B S T R A C T 2 2 J u l 2 0 2 6 5 2 0 2 6 2 0 8 0 0 0 - - 9 0 -

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