Delayed Release, Oral Dosage Compositions That Contain Amorphous CDDOME
BNRE20210001BUndetermined Publication Date: 2022-10-31REATA PHARMACEUTICALS HOLDINGS LLC
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Patent Information
- Application Number
- BNRE20210001
- Authority / Receiving Office
- BN · BN
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2009-02-13
- Filing Date
- 2021-02-09
- Publication Date
- 2022-10-31
- Estimated Expiration
- 2041-02-09
Abstract
Pharmaceutical formulations exhibit a desirably low Cmax, among other properties, that contain particles of amorphous barsoxolone methyl, either in pure form or in the form of a solid dispersion, admixed with particles of a hydrophilic binding agent. Such formulations possess the advantage of higher oral bioavailability, relative to formulations based on the crystalline form of bardoxolone methyl.
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