Insecticidal composition, process and method for pest control with dinotefuran and bifenthrin.

Description

1 / 12 Insecticidal composition, process and method for pest control with dinotefuran and bifenthrin. Technical Sector.

[01] This invention discloses an insecticide composed of dinotefuran and bifenthrin in effective quantities as a means of controlling unwanted pests, and is situated in the field of plant preservation products and / or plant parts thereof. State of the Art.

[02] The decline in agricultural production due to the presence of insects is a problem in which science is constantly working to find solutions that aim to help farmers minimize losses and maximize the productive yield of their crops, since the use of insecticides and pesticides is increasingly employed and this has made pests resistant to control, a fact that forces the growth of the demand for conducting trials to improve plant treatment.

[03] One way to contribute to plant treatment is revealed here with the application of an insecticide composed of dinotefuran and bifenthrin in quantities effective for protecting plants, plant propagation materials and their growing environment against pest attack and infestation.

[04] The combined use of two active ingredients with different mechanisms of action reduces the risk of resistance development by pests, as insect populations have less chance of adapting simultaneously to both modes of action.

[05] Bifenthrin is a pyrethroid widely used due to its high efficacy and rapid action. It has been an important active ingredient in several insecticide formulations;

[06] Dinotefuram is a systemic neonicotinoid, widely used because of its easy absorption by plants and distribution through the vascular system. This provides control Petition 870250011881, dated 02 / 13 / 2025, page 5 / 20 2 / 12 extended and ability to target hard-to-control pests that feed on the plant;

[07] Dinotefuran and bifenthrin are active ingredients frequently used due to their effective properties in pest control. They are used individually or in combination with other substances in insecticide formulations. However, it is important to note that, although both active ingredients are common in compounds intended for pest control, the specific mixture of dinotefuran and bifenthrin in the same compound is not a combination found on the market. Summary of the Invention.

[08] This invention relates to a compound that aims to control pests and encompasses the application of effective amounts of insecticide comprising the combination of bifenthrin and dinotefuran in effective amounts to a plant, plant propagation materials, growing environment, pests or their food source, habitat or growing sites.

[09] As the first component of this composition, dinotefuran is a systemic insecticide belonging to the neonicotinoid class. Its mechanism of action is based on the modulation of nicotinic acetylcholine receptors (nAChRs) in the central nervous system of insects. It acts directly on synapses, causing continuous nerve excitation, which leads to paralysis and death of the insect. Therefore, it offers rapid and effective pest control in various crops, with systemic and residual action that protects all parts of the plant. Its rapid absorption, low cross-resistance, and compatibility with integrated pest management make it a valuable choice for farmers seeking a versatile and long-term solution for agricultural pest control.

[10] As the second component of this composition, bifenthrin is an insecticide and acaricide belonging to the class of pyrethroids, a group of chemical compounds known for their action Petition 870250011881, dated 02 / 13 / 2025, page 6 / 20 3 / 12 fast-acting on the nervous system of insects. Therefore, it offers rapid and effective control of a wide range of agricultural pests, with prolonged residual action and low water solubility. Its versatility in application methods, combined with its compatibility with integrated pest management, makes it an important tool in sustainable pest management, protecting crops with less need for reapplication and with controlled environmental impact.

[11] This mixture combines the benefits of two distinct mechanisms of action, providing more complete and effective pest control. This combination is particularly useful in integrated pest management strategies, allowing for rapid and long-lasting control over a wide range of insects, both in immature and adult stages.

[12] The insecticidal combination of these two active ingredients offers systemic action (dinotefuran) and contact and ingestion action (bifenthrin), providing a comprehensive control effect for both insects that feed on internal parts of plants and those that are in contact with the surface.

[13] This invention also relates to the use of an insecticide composed of dinotefuran and bifenthrin in effective quantities for the control of selected pests from the order Hemiptera, Coleoptera, Lepidoptera, Diptera and Isoptera.

[14] This invention also aims to provide a composition that can be used at lower dosage rates compared to other insecticides and insecticidal compositions, in order to avoid adverse toxicological or environmental effects.

[15] In addition to the aspects already mentioned in the paragraphs above, this invention relates to the use of dinotefuran and bifenthrin in effective quantities as an insecticide to protect avocado, pineapple, pumpkin, zucchini, black wattle, açaí, chard, acerola, watercress, lettuce, cotton, garlic, chicory, peanut plants, Petition 870250011881, dated 02 / 13 / 2025, page 7 / 20 4 / 12 blackberry, annonaceae, rice, oats, olives, bananas, potatoes, sweet potatoes, yacon, eggplant, beetroot, broccoli, cocoa, coffee, cashew, sugarcane, canola, persimmon, yam, star fruit, Brazil nut, onion, carrot, rye, barley, shallot, chicory, chayote, citrus, coconut, cabbage, Chinese cabbage, Brussels sprouts, cauliflower, cupuaçu, palm oil, duboisia, peas, spinach, stevia, eucalyptus, beans, figs, raspberries, tobacco, sesame, sunflower, guava, chickpeas, guarana, eggplant, lentils, lychee, flaxseed, hops, apples, macadamia nuts, papaya, castor bean, cassava, arracacha, mango, mangaba, passion fruit, gherkin, watermelon, melon, millet, corn, blueberry, strawberry, mustard, turnip, pecan, palm, pastures, cucumber, pear, peach, pepper, bell pepper, pine nut, dragon fruit, pitanga, ornamental plants, peach palm, okra, kiwi, radish, cabbage, pomegranate, arugula, soybean, sorghum, tomato, wheat, triticale and grape, their plant propagation material or their growing environment,from attack or infestation by selected pests from Mahanarva fimbriolata, Bemisia tabaci race B, Euschistus heros, Nezara viridula, Piezodorus guildinii, Alabama argilácea, Anthonomus grandis, Helicoverpa armígera, Spodoptera frugiperda, Tetranychus urticae, Lyriomyza huidobrensis, Heterotermes tenuis, Procornitermes triacifer, Brevipalpus phoenicis, Diaphorina citri, Ecdytolopha aurantiana, Orthezia praelonga, Panonychus citri, Aphis gossypii, Empoasca kraemeri, Agrotis ípsilon, Lagarta-rosca, Epitrix fasciata, Faustinus cubae, Polyphagotarsonemus latus, Selenothrips rubrocinctus, Anticarsia gemmatalis, Neoleucinodes elegantalis, Tuta absoluta and their aggregations.,

[16] Pests, and especially insects of the orders Hemiptera, Coleoptera, Lepidoptera, Diptera and Isoptera, ruin harvested and growing crops, causing large economic losses in the food chain. A major threat in relation to these pests, Nezara viridula, feeds directly on the pods, sucks the grains and can cause a drop in productivity, a reduction in grain quality or inject toxins, causing deformities to the plants. With Petition 870250011881, dated 02 / 13 / 2025, page 8 / 20 Regarding soybeans, this damage can affect productivity by up to 30% and result in losses of up to 2 billion dollars per harvest. For corn, productivity losses can reach 20%, with losses of 900 million dollars. In cotton, this pest can lead to losses of 500 million dollars with a decrease of about 25% in productivity. Pest resistance to existing insecticides and dual insecticide compositions is one of the greatest difficulties for large-scale crops. It is known in the field that products planted on a large scale, such as soybeans, sugarcane, corn, and cotton, are particularly vulnerable to attack or infestation by insect pests of the orders Hemiptera, Coleoptera, Lepidoptera, Diptera, and Isoptera.

[17] The composition of dinotefuran and bifenthrin produces evident synergistic effects in which the active ingredients do not conflict with each other, which reduces the amount of product needed when applied to crops and lowers the costs of other insecticides.

[18] The mixture is formulated to maximize the synergy between the active ingredients, enhancing pest control and minimizing the chance of pest resistance. The composition of the present invention facilitates application, as ready-mixed blends combine different active ingredients in a single formulation, which reduces the number of applications required and simplifies pest management. This saves time, labor, and reduces operational complexity. With this mixture, there is no need for tank mixing, which reduces errors and provides greater safety in the risks of dosage errors and chemical incompatibilities, ensuring greater product efficacy. In addition, it has multiple control to act on different pests simultaneously, broadening the spectrum of action and providing greater crop protection with a single application.

[19] As used herein, the expression “pest resistance” means resistance of pest insects to other insecticides and insecticide mixtures. Petition 870250011881, dated 02 / 13 / 2025, page 9 / 20 6 / 12

[20] As a result, selected plants can be efficiently protected against these pests, so as to avoid a reduction in crop yield. In this particular, it is an important benefit of the composition, according to this invention, that the composition is also suitable for controlling the pests mentioned above in case of resistance to conventional insecticides or insecticidal compositions, preferably at a dose of 0.5 kg-ml fpha-1.

[21] The combination of dinotefuran and bifenthrin provides an effective and long-lasting solution for pest control, with rapid and residual action, wide application versatility and lower risk of resistance. This combination acts on different modes of action and life stages of pests, ensuring more complete and efficient management in various crops.

[22] The compound of this invention shall hereinafter be referred to as “composition according to the present invention”. Remarks regarding preferred embodiments of the composition according to the present invention shall be understood as the preferred embodiment alone, as well as combinations with each other and in combinations with favorite manipulations in relation to its application and methods which encompass the application of the composition according to the present invention in accordance with what is defined herein and in combination with favorite manipulations with reference to the agrochemical composition stipulated herein.

[23] The composition comprising dinotefuran and bifenthrin as described herein typically includes dinotefuran and bifenthrin subjected to the process in weight ratios from 1:100 to 100:1 to 1:1.

[24] The mixture can be applied via foliar spraying, seed treatment or to the soil, offering flexibility for different cropping systems and agricultural practices.

[25] The process of applying the composition, according to the present invention, according to its application or method, includes Petition 870250011881, dated 02 / 13 / 2025, page 10 / 20 7 / 12 contact with the plant or plant propagation material and contact with its growth environment. The term “growth environment” should be understood as the environment where the plant is growing, whether it be soil or water. Furthermore, the method according to the present invention refers to a manipulation to be applied to pests, their food source, habitat or growth environment.

[26] The pests reported are of importance in relation to specific plants. Pests may appear on wild-type plants and plants that have been altered by conventional cultivation, mutagenesis, genetic engineering or one of these fusions. In one embodiment, the term “plant” refers to a plant that has been altered by conventional cultivation, mutagenesis, genetic engineering or one of these fusions.

[27] The means and their applications, according to this invention, may also involve a phase of determining whether pests are resistant to certain insecticides. This phase generally involves collecting a sample to be treated, before the actual application of dinotefuran and bifenthrin or a composition of dinotefuran and bifenthrin, and testing using, for example, any appropriate phenotypic, biochemical or molecular biological method to determine resistance / sensitivity. Detailed Description.

[28] The following are appropriate formulations and applications with respect to the present application. These preferred manipulations refer to (i) the composition according to this invention, as well as the application and means of applying said composition, (ii) the application and means of applying bifenthrin according to this invention, and (iii) the application and means of applying dinotefuran according to this invention. When referring to “the composition according to this invention dinotefuran and bifenthrin,” it should be understood that the manipulations are presented in combination with (i) the composition according to this invention as well as the application and means of applying said composition, Petition 870250011881, dated 02 / 13 / 2025, page 11 / 20 8 / 12 (ii) application and means encompassing the application of bifenthrin according to this invention and (iii) application and means encompassing the application of dinotefuran according to this invention, respectively.

[29] According to this invention, the dinotefuran and bifenthrin composition can be provided in the form of an agrochemical mixture comprising the composition according to this invention, dinotefuran and bifenthrin. An agrochemical mixture comprises an effective insecticidal quantity of a composition according to this invention, dinotefuran and bifenthrin. The expression “effective insecticidal quantity” is set forth below. The compositions according to this invention, dinotefuran and bifenthrin, can be converted into customary types of agrochemical mixtures, such as solutions, emulsions, suspensions, dry powders, powders, pastes, granules and compositions thereof.Examples of mixture types include suspensions (such as SC, OD, FS), emulsifiable concentrates (such as EC), emulsions (such as EW, EO, ES, ME), pastes, dry or wettable powders (such as WP, SP, WS, DP, DS), granules (such as WG, SG, GR, FG, GG, MG) and insecticidal articles (such as LN), as well as gel formulations for the treatment of plant propagation material, such as seeds (such as GF).

[30] Agrochemical mixtures commonly comprise from 0.01 to 95%, preferably from 0.1 to 90%, and most preferably from 0.5 to 75% by weight of active substance. The active substances are employed in a purity of 90% to 100%, preferably from 95% to 100%.

[31] Various types of oils, humectants, adjuvants, fertilizers or micronutrients and other pesticides (such as herbicides, insecticides, fungicides, growth regulators and safety agents) may be added to the active substances or to the compositions comprising them as a premix or, where appropriate, not until immediately before use (tank mixing). These agents may be mixed with the compositions according to the present invention in a weight ratio of 1:100 to 100:1 to 1:1.

[32] Additionally, in a manipulation, components Petition 870250011881, dated 02 / 13 / 2025, page 12 / 20 9 / 12 individual components of the mixture according to this invention, or partially premixed components, such as components comprising mixtures according to the present invention, dinotefuran and bifenthrin, can be mixed by the user in a spray tank and additional additives and auxiliaries can be added, if appropriate.

[33] In a further embodiment, individual components of the composition according to the present invention or partially premixed components, such as components comprising mixtures according to the present invention, dinotefuran and bifenthrin, may be applied together (such as after tank mixing) or consecutively.

[34] The mixtures according to the present invention, dinotefuran and bifenthrin, are suitable for use in protecting crops, plants, plant propagation materials, such as seeds, or their growing site against pest attacks or infestation.

[35] The present invention also relates, therefore, to a method of plant protection, comprising contacting crops, plants, plant propagation materials, such as seeds, or their growing location to be protected against insect attack or infestation, with an effective amount as an insecticide of a mixture according to the present invention, dinotefuran and bifenthrin. The mixtures according to the present invention, dinotefuran and bifenthrin, are also suitable for use in combating or controlling pests. The present invention also relates, therefore, to a method of combating or controlling pests, comprising contacting the pests, their habitat, growing location, food source, crops, plants, plant propagation materials, such as seeds, soil, area, material or environment in which the insects are developing or may develop, with an effective amount as an insecticide of a mixture according to the present invention, dinotefuran or bifenthrin.The mixtures are in accordance. Petition 870250011881, dated 02 / 13 / 2025, page 13 / 20 10 / 12 with the present invention, dinotefuran or bifenthrin are effective by contact. Furthermore, the mixtures according to the present invention, dinotefuran or bifenthrin, can be applied to any and all stages of development.

[36] The mixtures according to the present invention, dinotefuran and bifenthrin, can be applied as such or in the form of compositions comprising them as defined above.

[37] As used herein, the term contact includes direct contact (application of the compounds / mixtures / compositions directly onto the pest animal or plant, typically to the foliage, stems or roots of the plant) and indirect contact (application of the compounds / mixtures / compositions to the site, i.e., habitat, growth site, plant, seed, soil, area, material or environment in which the pest is growing or may grow, of the pest animal and / or plant).

[38] The term animal pest includes arthropods, gastropods and nematodes. Preferred pests according to the present invention are arthropods, preferably insects and arachnids, particularly insects. Insects that are of specific relevance to crops are typically referred to as crop pest insects.

[39] The term harvest designates growing and harvested crops.

[40] The term plant includes cereals, such as durum wheat and others, barley, rye, triticale, oats, rice or maize (forage maize, sweet maize and field maize); beet, such as sugar beet or fodder beet; fruits, such as pomes, drupes or soft fruits, such as apples, pears, plums, peaches, nectarines, almonds, cherries, papayas, strawberries, raspberries, currants or blackcurrants; leguminous plants, such as beans, lentils, peas, alfalfa or soybeans; oilseed plants, such as rapeseed (canola), wild turnip, mustard, olives, sunflower, coconut, cocoa beans, castor plants, oil palm, peanuts or soybeans; cucurbits, such as pumpkins, squash, cucumbers Petition 870250011881, dated 02 / 13 / 2025, p. 14 / 20 11 / 12 or melons; fiber plants, such as cotton, flax, hemp, or jute; citrus fruits, such as oranges, lemons, grapefruits, or tangerines; vegetables, such as eggplant, spinach, lettuce (e.g., iceberg lettuce), endive, cabbage, asparagus, carrots, onions, garlic, leeks, tomatoes, potatoes, cucurbits, or sweet peppers; laurel plants, such as avocados, cinnamon, or camphor; raw material and energy plants, such as corn, soybeans, canola, sugarcane, or oil palm; tobacco; almonds, such as walnuts; pistachios; coffee; tea; bananas; grapes (table grapes and juice grapes); hops; sweetener leaf (also known as stevia); Natural rubber plants or forest and ornamental plants, such as flowers (e.g., carnations, petunias, geraniums / Pelargonium, pansies and impatiens), shrubs, broadleaf trees (e.g., poplar) or perennials such as conifers; eucalyptus; grass; turf; grass for animal feed or ornamental uses.Preferred plants include potatoes, beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, canola, legumes, sunflowers, coffee or sugarcane; fruits; grapes; ornamental plants; or vegetables such as cucumbers, tomatoes, beans or pumpkins.

[41] The term “plant propagation material” designates all reproductive parts of the plant, such as seeds and plant material such as cuttings and tubers (e.g., potatoes), which can be used for plant propagation. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, seedlings and other plant parts. Seedlings and young plants, which must be transplanted after germination or after emergence from the soil, may also be included. These plant propagation materials may be treated prophylactically with a plant protection mixture at planting, transplanting or before it.

[42] The term “seed” encompasses seeds and plant propagules of all kinds, including, but not limited to, true seeds, seed pieces, sprouts, stolons, bulbs, fruits, tubers, grains, cuttings, cut shoots and the like, and indicates, in Petition 870250011881, dated 02 / 13 / 2025, p. 15 / 20 12 / 12 a preferred achievement, real seeds.

[43] Generally, “effective amount as an insecticide” indicates the amount of active ingredient required to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention and removal, destruction or otherwise reduction of the occurrence and activity of the target organism. The effective amount as an insecticide may vary for the various compounds / mixtures / compositions used in the present invention. An effective amount as an insecticide of the compositions will also vary according to prevailing conditions, such as the desired insecticidal effect and duration, weather conditions, target species, location, method of application and the like.

[44] For use in the treatment of producing plants, for example, by means of foliar application, the application rate of the active ingredients according to the present invention may be in the range of 0.0001 L to 1000 L.

[45] As used herein, “effective and non-phytotoxic quantity” means that the mixture, dinotefuran and bifenthrin, is used in a quantity that allows the desired effect to be obtained, but that does not generate any phytotoxic symptoms on the treated plant or on the plant grown from the treated propagule or treated soil. Petition 870250011881, dated 02 / 13 / 2025, page 16 / 20

Claims

1 / 1 CLAIMS 1 - INSECTICIDE COMPOSITION, characterized by comprising dinotefuran and bifenthrin. 2 - INSECTICIDE COMPOSITION, as claimed in 1, characterized by dinotefuran and bifenthrin being diluted in solvent in a weight ratio of 1:100 to 100:

1. 3 - PROCESS, characterized by application to plants, plant propagation material or their growth environment against attack or infestation by pests. 4 - METHOD, characterized by the fact that the method involves the application of pesticide compositions to the plant, plant propagation materials, its growth environment, pests, habitat or growth sites. 5 - METHOD, as claimed in 4, characterized in that the targets are selected from pest insects of the orders Hemiptera, Coleoptera, Lepidoptera, Diptera and Isoptera and their aggregations. 6 - METHOD, as claimed in claims 4-5, characterized in that the means comprises the treatment of pests, their food source, their growth environment, or plant, seed, soil, area, material, or environment in which the insects are growing or may grow, or the materials, plants, seeds, soils, surfaces, or spaces to be protected from attack or infestation by pests with an effective quantity as a pesticide of the pesticide compositions as defined in any of claims 1 to 2. 7 - METHOD, as claimed in 4-6, characterized in that the compositions are applied to the foliage of the plants in a quantity of 1 g 10000 g per hectare. Petition 870250065665, dated 07 / 29 / 2025, page 5 / 5