Pesticide mixture, pesticide composition and method for controlling pest in a culture

Abstract

ABSTRACT “PESTICIDE MIXTURE, PESTICIDE COMPOSITION, METHOD FOR CONTROLLING PEST IN A CROP AND KIT” A pesticide mixture including (a) spinetoram; and (b) a compound from group A selected from novaluron, pyroproxyfen, tau-fluvalinate, and a combination thereof. 1 / 1

Description

Pesticide Mixture, Pesticide Composition and Method for Controlling Pests in a Crop - Technical Field

[0001] The present invention disclosure relates to a pesticide mixture for pest control. Background of the invention

[0002] Mixtures of active agents are described in the literature. However, pest control does not always meet the needs of agricultural practice. Additionally, the effectiveness of mixtures is not entirely satisfactory in the areas of pest control and / or toxicological and / or environmental effects.

[0003] Spinetoram is a semi-synthetic spinosin. Spinetoram is a mixture of 50-90% of (2R, 3aR, 5aR, 5bS, 9S, 13S, 14R,16aS,16bR)-2-(6-deoxy-3-0-ethyl-2,4-di-O-methyl-a-Lmannopyranosyloxy)-13-[(2R,5S,6R)-5-(dimethylamino)tetrahydro6-methylpyran-2-yloxy]-9-ethyl-2,3,3a,4,5, 5a, 5b, 6, 9, 10, 11, 12,13,14,16a,16b-hexadecahidro-14-methyl-1H-as-indaceno[3, 2d] oxacyclododecin-7,15-diona and 50-10% of (2S, 3aR, 5aS, 5bS, 9S, 13S, 14R, 16aS, 16bS) -2- (6-deoxy-3-0-ethyl2,4-di-O-methyl-aL-mannopyranosyloxy)-13-[(2R,5S,6R)-5(dimethylamino)tetrah hydro-6-methylpyran-2-yloxy]-9-ethyl2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetra-decahydro-4, 14dimethyl-1H-as-indaceno[3,2-d]oxacyclododecin-7, 15-diona.

[0004] [Compendium of Pesticide Common Names - available at: www.alanwood.net / pesticides / index.html] .

[0005] Spinetoram was described in U.S. Patent No. 6,001,981. Spinetoram was also described in The EPesticide Manual (Version 5.0.1, 2010, 15th Edition, Publisher: CDS Tomlin), Entry Number: 783. Petition 870260058041, dated 06 / 15 / 2026, page 9 / 116 2 / 51 (ü) component (i) ; and

[0006] Spinetoram: Mixture of 50-90% of 50-10% of component (ii) .

[0007] Pesticide mixtures comprising spinosyn have been described in international publications WO 2010 / 052129, WO 2010 / 030501, US 6,444,667, US 6,686,387 and US 2006 / 0211655.

[0008] The compositions and mixtures do not exert a satisfactory control effect in some cases and therefore there is still a need for the development of new pesticide mixtures having a satisfactory control effect.

[0009] Thus, it will be highly advantageous to have new combinations of spinetoram pesticide mixtures with various pesticides described in the invention, having a very good control effect on various pests, improved control over pests, broadening of the control spectrum, and / or favorable maintenance and reduced toxicological and environmental effects. Summary of the invention

[0010] According to one aspect, it is provided with a pesticide mixture comprising (a) spinetoram; and (b) a compound from group A selected from novaluron, pyriproxyfen, taufluvalinate, and a combination thereof.

[0011] According to another aspect, a is provided Petition 870260058041, dated 06 / 15 / 2026, page 10 / 116 3 / 51 pesticide composition comprising a pesticide mixture comprising (a) spinetoram; and (b) a compound from group A selected from novaluron, pyriproxyfen, taufluvalinate, and a combination thereof; and an agriculturally acceptable carrier.

[0012] According to a further aspect, a method is provided for controlling pests in a crop, comprising contacting the pests or a site where pest control is desired with a pesticide mixture comprising (a) spinetoram; and (b) a compound from group A selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof.

[0013] According to a further aspect, a kit is provided comprising (a) at least one container containing spinetoram; (b) at least one container containing a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof; and (c) instructions for applying said spinetoram and said group A compound to a pest or site where pest control is desired.

[0014] According to a further aspect, a kit is provided comprising (a) at least one container including (i) spinetoram; and (ii) a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof; and (b) instructions for applying said spinetoram and said group A compound to a plague or a site where plague control is desired. Detailed description of the invention

[0015] Before describing the invention in detail, it may be useful to provide definitions of certain terms used herein. Petition 870260058041, dated 06 / 15 / 2026, p. 11 / 116 4 / 51 in the present invention. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as is commonly understood by a person skilled in the art to which this invention pertains.

[0016] The use of terms a and an, and the, and similar references in the context of the invention description (especially in the context of the following claims) are constructed to cover both the plural and the singular, unless otherwise indicated herein or clearly contradicted by the context.

[0017] As used herein, the term culture includes reference to the whole plant, to plant organs (e.g., leaves, stem, branches, roots, trunk, limbs, shoots, fruits, etc.), or to plant cells.

[0018] As used herein, the term propagation material should be understood to denote all reproductive parts of the plant, such as seeds and spores, vegetative structures such as bulbs, shoots, tubers, rhizomes, root stalks, basal roots, stolons, and buds.

[0019] According to one aspect, a pesticide mixture is provided comprising (a) spinetoram; and (b) a compound from group A selected from novaluron, pyriproxyfen, taufluvalinate, and a combination thereof.

[0020] Spinetoram is a mixture of 50-90% of (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-2-(6-deoxy-3-O-ethyl2,4-di-O-methyl-aL-mannopyranosyloxy)-13-[(2R,5S,6R)-5(dime thylamino)tetrahydro-6-methylpyran-2-yloxy]-9-ethyl2,3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16b-hexadecahydro-14methyl-1 H-as-indacene[3,2-d]oxacyclododecin-7, 15-dione and 50-10% (2S,3aR,5aS,5bS,9S,13S,14R,16aS,16bS)-2-(6-deoxy Petition 870260058041, dated 06 / 15 / 2026, page 12 / 116 5 / 51 3-O-ethyl-2,4-di-O-methyl-aL-mannopyranosyloxy)-13-[(2R, 5Sr6R)5-(dimethylamino)tetrahydro-6-methylpyran-2-yloxy]-9-ethyl2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetra-decahydro-4, 14dimethyl-1H-as-indacene[3,2-d]oxacyclododecin-7, 15-dione.

[0021] [Compendium of Pesticide Common Names - available at: www.alanwood.net / pesticides / index.html] .

[0022] Spinetoram (also described in The E-Pesticide Manual (Version 5.0.1, 2010, 15th Edition, Publisher: CDS) Tomlin)), Entry number: 783. (CHjhrH^ ) QCh3cíh3CÍ OCh3 A .OCH,CHj / Q .Ao CÍh ( V Spinetoram: Mixture of 50-90% of component (i); and 50-10% of component (ii).

[0023] Novaluron ( ( + )-1-[3-chloro-4-(1,1,2-trifluoro-2trifluoromethoxyethoxy)phenyl]-3-(2,6-difluorobenzoyl)urea, Cl fi

[0024] It is described in: The E-Pesticide Manual (Version 5.0.1, 2010, 15th Edition, Publisher: CDS Tomlin), Entry number: 621.

[0025] Tau-fluvalinate ((RS)-0í-cyano-3-phenoxybenzyl-N-(2chloro-Oí,OC,Oí-trifluoro-p-tolyl)-D-valinato), Petition 870260058041, dated 06 / 15 / 2026, p. 13 / 116 6 / 51 H O II hl—CC H I CHj CH3

[0026] It is described in: The E-Pesticide Manual (Version 5.0.1, 2010, 15th Edition, Publisher: CDS Tomlin), Entry number: 423, and

[0027] Pyriproxyfen (4-phenoxyphenyl-(RS)-2-(2pyridyloxy)propyl-ether).

[0028] It is described in: The E-Pesticide Manual (Version 5.0.1, 2010, 15th Edition, Publisher: CDS Tomlin), Entry number: 749.

[0029] The compounds are also described in Compendium of Pesticide Common Names - available at: www.alanwood.net / pesticides / index.html.

[0030] According to another aspect, a pesticide composition is provided comprising a pesticide mixture as described in the present description; and an agriculturally acceptable carrier.

[0031] According to certain embodiments, the pesticide mixture may result in synergistic pesticide activity when applied to pests.

[0032] Synergy can be calculated according to Colby SR in an article entitled Calculating synergistic and antagonistic responses of herbicide combinations published in Journal Weeds, 1967, 15, p. 20-22, incorporated here by reference in its entirety. A pesticide composition comprising a mixture as described in the present description may improve the effectiveness of pesticide activity, may extend Petition 870260058041, dated 06 / 15 / 2026, page 14 / 116 7 / 51 the spectrum of control and / or allow minimizing the dosage of active ingredients being used when compared to the use of such individual pesticides alone.

[0033] According to one particular embodiment, the plague is selected from an insect, a mite, mollusks, or a combination thereof.

[0034] In one specific embodiment, the plague is an insect. In one specific embodiment, the plague is a mite. In one specific embodiment, the plague is a mollusk.

[0035] The term pesticide refers especially to insecticidal and / or miticidal activities. The term pesticide also refers to molluscidal activity.

[0036] According to a further aspect, a synergistic pesticide mixture comprising: (a) spinetoram; and (b) a compound from group A selected from novaluron, pyroproxyfen, tau-fluvalinate, and a combination thereof.

[0037] According to a further aspect, a pesticide composition is provided comprising a pesticide mixture as described in the present description in a synergistically effective amount; and an agriculturally acceptable carrier.

[0038] The composition may be for use in the agricultural control of pests in a crop or a site thereof, comprising contacting the agricultural pests or the food supply of the agricultural pest, habitat, breeding soil, or site with an effective amount of a mixture as described in the present description.

[0039] According to a further aspect, a method is provided for pest control in a crop, comprising Petition 870260058041, dated 06 / 15 / 2026, p. 15 / 116 8 / 51 contact the pests or a site where pest control is desired with a pesticide mixture comprising (a) spinetoram; and (b) a compound from group A selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof.

[0040] According to a further aspect, a method is provided for controlling pests in a crop, comprising contacting the pests or a site where pest control is desired with a composition comprising a pesticide mixture as described in the present description.

[0041] The site can be the soil or water in which the crop is growing.

[0042] The description further refers to a method for controlling pests in a crop or in propagation material thereof, comprising contacting the pests or the agricultural pest's food supply, habitat, breeding soil, or site with an amount of a combination of a pesticide mixture as described in the present invention.

[0043] According to certain embodiments, the weight ratio of spinetoram and a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof is 1:1000 to 1000:1. In one embodiment, the weight ratio of spinetoram and a group A compound is 1:100 to 100:1. In a further embodiment, the weight ratio of spinetoram and a group A compound is 1:50 to 50:1. In yet another embodiment, the weight ratio of spinetoram and a group A compound is 1:10 to 10:1. In a further embodiment, the weight ratio of spinetoram and Petition 870260058041, dated 06 / 15 / 2026, page 16 / 116 9 / 51 a compound from group A is 1:8 to 8:1. In a further embodiment, the weight ratio of spinetoram to a compound from group A is 1:5 to 5:1.

[0044] According to some embodiments, the weight ratio of spinetoram and a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof is 100:1 and below, 50:1 and below, 10:1 and below; 8:1 and below; 5:1 and below; 4:1 and below; 3:1 and below; 2:1 and below; 2:1 and below, 1.3:1 and below; 1:1 and below.

[0045] According to some embodiments, the weight ratio of spinetoram and a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof is 1:100 and above, 1:50 and above, 1:10 and above, 1:8 and above, 1:5 and above; 1:4 and above, 1:3 and above, 1:2 and above; 1:1.3 and above, 1:1 and above.

[0046] The weight ratio of spinetoram and a compound from group A selected from novaluron, pyriproxyfen, taufluvalinate, and a combination thereof may be in a range between any of the values ​​indicated above (e.g., 4:1 to 1:4; 4:1 to 1:3; 4:1 to 1:2, 4:1 to 1:1.3; 4:1 to 1:1, 3:1 to 1:4, etc.).

[0047] As used here, the term ha refers to hectare.

[0048] According to certain embodiments, the application rate of spinetoram is 0.5 grams per hectare (g / ha) for 50 g / ha, specifically 1 g / ha for 500 g / ha, specifically 1 g / ha for 250 g / ha, more specifically 1 g / ha for 100 g / ha.

[0049] According to certain realizations, the rate of Petition 870260058041, dated 06 / 15 / 2026, p. 17 / 116 10 / 51 application of spinetoram are 0.5 g / ha and above, 1 g / ha and above, 1.5 g / ha and above, 2 g / ha and above, 2.5 g / ha and above, 3 g / ha and above, 3.5 g / ha and above, 4 g / ha and above, 4.5 g / ha and above, 5 g / ha and above, 5.5 g / ha and above, 6 g / ha and above.

[0050] According to certain embodiments, the application rate of spinetoram is 500 g / ha and below, 250 g / ha and below, 200 g / ha and below, 150 g / ha and below, 100 g / ha and below, 50 g / ha and below, 20 g / ha and below, 10 g / ha and below, 8 g / ha and below. The application rate of spinetoram may be any range between any of the values ​​indicated above.

[0051] According to certain embodiments, the application rate of a compound from group A is 0.5 g / ha to 500 g / ha, specifically 1 g / ha to 500 g / ha, specifically 1 g / ha to 250 g / ha, more specifically 1 g / ha to 100 g / ha.

[0052] According to certain embodiments, the application rate of a compound from group A is 0.5 g / ha and above, 1 g / ha and above, 1.5 g / ha and above, 2 g / ha and above, 2.5 g / ha and above, 3 g / ha and above, 3.5 g / ha and above, 4 g / ha and above, 4.5 g / ha and above, 5 g / ha and above, 5.5 g / ha and above, 6 g / ha and above.

[0053] According to certain embodiments, the application rate of a compound from group A is 500 g / ha and below, 250 g / ha and below, 200 g / ha and below, 150 g / ha and below, 100 g / ha and below, 50 g / ha and below, 20 g / ha and below, 10 g / ha and below, 8 g / ha and below.

[0054] The application rate of a compound from group A selected from novaluron, pyriproxyfen, taufluvalinate, may be any range between any of the values ​​indicated. Petition 870260058041, dated 06 / 15 / 2026, page 18 / 116 11 / 51

[0055] According to certain embodiments, the application rates of the pesticide mixture as described in the present invention are from 1 g / ha to 100 g / ha. In a specific embodiment, the application rate of the pesticide mixture as described in the present description is from 2 g / ha to 1000 g / ha.

[0056] In another embodiment, the application rate of the combination (mixture) of spinetoram and a compound from group A is 1 g / ha to 500 g / ha. In yet another embodiment, the application rate of the combination of spinetoram and a compound from group A is 1 g / ha to 250 g / ha. In yet another embodiment, the application rate of the combination of spinetoram and a compound from group A is 1 g / ha to 200 g / ha. In yet another embodiment, the application rate of the combination of spinetoram and a compound from group A is 1 g / ha to 150 g / ha. In yet another embodiment, the application rate of the combination of spinetoram and a compound from group A is 1 g / ha to 100 g / ha. In yet another embodiment, the application rate of the combination of spinetoram and a compound from group A is 1 g / ha to 50 g / ha. The ranges above refer to the application rates of a combination of spinetoram and a compound from group A (denominated by the sum of the application rates of both active ingredients).

[0057] In one embodiment, spinetoram and the group A compound are applied concomitantly or sequentially.

[0058] The application of spinetoram and group A compound can be in any desired order.

[0059] The term “simultaneously applied” or “concomitantly applied” means the successive administration of a composition including spinetoram, and then the administration of a composition of a compound from group A. Petition 870260058041, dated 06 / 15 / 2026, p. 19 / 116 12 / 51 When administered sequentially, spinetoram and the group A compound are included in separate compositions. If spinetoram and the group A compound are administered sequentially, the order of administration may be alternated.

[0060] The term “simultaneously applied” or “concomitantly applied” means the administration of the compound substantially concomitantly. These terms encompass not only the administration of spinetoram and the group A compound according to the invention in a single formulation (composition), but also the administration of each compound (i.e., spinetoram and the group A compound) in its own separate formulation. When separate formulations are used, the compounds can be administered essentially at the same time, i.e., concomitantly.

[0061] The application can be by any method known in the art, in particular by methods such as spraying, dipping, sweeping, soaking, coating and dredging.

[0062] The description further refers to the use of a composition comprising a pesticide mixture as described in this description for pest control in a crop or on a site thereof.

[0063] The description further refers to a composition comprising a pesticide mixture as described in this description for use in controlling pests in a crop or on a site thereof. In a particular embodiment, the pesticide mixture is in a synergistic effective amount. Petition 870260058041, dated 06 / 15 / 2026, p. 20 / 116 13 / 51

[0064] The crop includes, but is not limited to, vegetables, fruits, soybeans, tobacco, cultivated mushrooms, cotton, rapeseed, cereals, sunflower, peanuts, rice, corn, coffee, beans, peas, cassava (yucca), sugarcane, clover, spices, ornamental plants, coconut, beet.

[0065] In one embodiment, the crop may be vegetables, such as peppers, cabbage, broccoli, asparagus, artichokes, pumpkin, lettuce, turnips, spinach, cauliflower, melon, watermelon, cucumber, carrots, onions, garlic, squash and potatoes; fruits, for example, pome and stone fruits and grapes, such as walnuts, kiwi, banana, avocado, olives, passion fruit, almonds, pineapple, apples, pears, plums, peaches and cherries, tropical and subtropical fruits, wine and table grapes, citrus fruits, such as oranges, lemons, grapefruits and limes; cereals, such as wheat, barley, rye, hybrid cereal (triticale), oats, sorghum; corn (maize), such as sweet corn; beet, such as sugar beet, fodder beet; spices, such as cardamom; ornamental plants, such as flowers, Christmas trees.

[0066] In another embodiment, the insects / pests are from the order Coleoptera, such as Acanthoscelides spp. (weevil), Acanthoscelides obtectus (common bean weevil), Agrilus planipennis (emerald ash borer), Agriotes spp. (borer), Anoplophora glabripennis (Asian beetle), Anthonomus spp. (weevil), Anthonomus grandis (capsule weevil), Aphidius spp., Apion spp. (weevils), Apogonia spp. (larvae), Ataenius spretulus (Black Turgrass Ataenius), Atomaria linearis (pygmy mangold beetle), Aulacophore spp., Bothynoderes punctiventris (beet root weevil), Bruchus spp. (weevils), Bruchus pisorum (pea weevil), Cacoesia spp., Petition 870260058041, dated 06 / 15 / 2026, p. 21 / 116 14 / 51 Callosobruchus maculatus (southern cow pea weevil), Carpophilus hemipteras (dried fruit beetle), Cassida vittata, Cerosterna spp, Cerotoma spp. (chrysomeids), Cerotoma trifurcata (bean leaf beetle), Ceutorhynchus spp. (weevils), Ceutorhynchus assimilis (cabbage seedpod weevil), Ceutorhynchus napi (cabbage curculio), Chaetocnema spp. (chrysomelids), Colaspis spp. (soil beetles), Conoderus scalaris, Conoderus stigmosus, Conotrachelus nenuphar (plum curculio), Cotinus nitidis (Green June beetle), Crioceris asparagi (asparagus beetle), Cryptolestes ferrugineus (rusty grain beetle), Cryptolestes pusillus (flat grain beetle), Cryptolestes turcicus (Turkish grain beetle), Ctenicera spp. (wireworms), Curculio spp. (weevils), Cyclocephala spp. (grubs), Cylindrocpturus adspersus (sunflower stem weevil), Deporaus marginatus (mango leaf-cutting weevil), Dermestes lardarius (larder beetle), Dermestes maculates (hide beetle), Diabrotica spp.(chrysolemids), Epilachna varivestis (Mexican bean beetle), Faustinus cubae, Hylobius pales (pales weevil), Hypera spp. (weevils), Hypera postica (alfalfa weevil), Hyperdoes spp. (Hyperodes weevil), Hypothenemus hampei (coffee berry beetle), Ips spp. (engravers), Lasioderma serricorne (cigarette beetle), Leptinotarsa ​​decemlineata (Colorado potato beetle), Liogenys futscus, Liogenys suturalis, Lissorhoptrus oryzophilus (rice water weevil), Lyctus spp. (wood beetles / powder post beetles), Maecolaspis joliveti, Megascelis spp., Melanotus communis, Meligethes spp., Meligethes aeneus (blossom beetle), Melolontha melolontha (common European cockchafer), Oberea brevis, Oberea linearis, Oryctes rhinoceros (date palm beetle), Oryzaephilus mercator (merchant grain beetle), Oryzaephilus. Petition 870260058041, dated 15 / 06 / 2026, p. 22 / 116 15 / 51 surinamensis (sawtoothed grain beetle), Otiorhynchus spp. (weevils), Oulema melanopus (cereal leaf beetle), Oulema oryzae, Pantomorus spp. (weevils ), Phyllophaga spp. (MayJJune beetle), Phyllophaga cuyabana, Phyllotreta spp. (chrysomelids), Phynchites spp., Popillia japonica (Japanese beetle), Prostephanus truncates (larger grain borer), Rhizopertha dominica (smaller grain borer), Rhizotrogus spp. (Eurpoean chafer), Rhynchophorus spp. (weevils), Scolytus spp. (wood beetles), Shenophorus spp. (Billbug), Sitona lineatus (pea leaf weevil), Sitophilus spp. (grain weevils), Sitophilus granaries (granary weevil), Sitophilus oryzae (rice weevil), Stegobium paniceum (drugstore beetle), Tribolium spp. (flour beetles), Tribolium castaneum (red flour beetle), Tribolium confusum (confused flour beetle), Trogoderma variabile (warehouse beetle) e Zabrus tenebioides. Ainda em uma outra concretização, os insetos / pestes da ordem Diptera, tais como Aedes spp. (mosquitos), Agromyza frontella (alfalfa blotch leafminer), Agromyza spp. (leaf miner flies), Anastrepha spp. (fruit flies), Anastrepha suspensa (Caribbean fruit fly), Anopheles spp. (mosquitoes), Batrocera spp. (fruit flies), Bactrocera cucurbitae (melon fly), Bactrocera dorsalis (oriental fruit fly), Ceratitis spp. (fruit flies), Ceratitis capitata (Mediterranea fruit fly), Chrysops spp. (deer flies), Cocliliomyia spp.(screwworms), Contarinia spp. (Gall midges), Culex spp. (mosquitoes), Dasineura spp. (gall midges), Dasineura brassicae (cabbage gall midge), Delia spp., Delia platura (seedcorn maggot), Drosophila spp. (vinegar flies), Fannia spp. (filth flies), Fannia canicularis (little house fly), Fannia scalaris (latrine fly), Gasterophilus intestinalis (horse bot fly), Gracillia. Petição 870260058041, de 15 / 06 / 2026, pág. 23 / 116 16 / 51 perseae, Haematobia irritans (horn fly), Hylemyia spp. (root maggots) , Hypoderma lineatum (common cattle grub), Liriomyza spp. (leafminer flies), Liriomyza brassica (serpentine leafminer), Melophagus ovinus (sheep ked), Musca spp. (muscid flies), Musca autumnalis (face fly), Musca domestica (house fly), Oestrus ovis (sheep boat fly), Oscinella frit (grass fly), Pegomyia betae (beet leafminer), Phorbia spp maggots), Sitodiplosis mosellana (orange wheat blossom midge), Stomoxys calcitrans (stable fly), Tabanus spp. (horse flies) and Tipula spp. (crane flies). In yet another embodiment, the insect pests are of the order Hemiptera, such as Acrosternum hilare (green stink bug), Blissus leucopterus (chinch bug), Calocoris norvegicus (potato mirid), Cimex hemipterus (tropical bed bug), Cimex lectularius (bed bug), Dichelops melacanthus (Dallas), Dagbertus fasciatus, Dichelops furcatus, Dysdercus suturellus (cotton stainer), Edessa meditabunda, Eurygaster maura (cereal bug), Euschistus heros, Euschistus servus (brown stink bug), Helopeltis antonii, Helopeltis theivora (tea blight plantbug), Lagynotomus spp. (stink bugs), Leptocorisa oratorius, Leptocorisa varicornis, Lygus spp. (plant bugs), Lygus hesperus (western tarnished plant bug), Maconellicoccus hirsutus, Neurocolpus longirostris, Nezara viridula (southern green stink bug), Paratrioza cockerelli, Phytocoris spp.(plant bugs), Phytocoris californicus, Phytocoris relativus, Piezodorus guildingi, Poecilocapsus lineatus (fourlined plant bug), Psallus vaccinicola, Pseudacysta perseae, Scaptocoris castanea and Triatoma spp. (kissing bugs / insects that suck. Petition 870260058041, dated 06 / 15 / 2026, page 24 / 116 17 / 51 blood) .

[0067] In yet another embodiment, pest insects are of the order Homoptera, such as Acrythosiphon pisum (pea aphid), Adelges spp. (adelgids), Aleurodes proletella (cabbage whitefly), Aleurodicus disperses, Aleurothrixus floccosus (woolly whitefly), Aluacaspis spp., Amrasca bigutella bigutella, Aphrophora spp. (leafhoppers), Aonidiella aurantii (California red scale), Aphis spp. (aphids), Aphis gossypii (cotton aphid), Aphis fabae (aphid), Aphis pomi (apple aphid), Aulacorthum solani (foxglove aphid), Bemisia spp. (whiteflies) , Bemisia argentifolii, Bemisia tabaci (sweet potato whitefly), Brachycolus noxius (Russian aphid), Brachycorynella asparagi (asparagus aphid), Brevennia rehi, Brevicoryne brassicae (cabbage aphid), Ceroplastes spp. (scales), Ceroplastes rubens (red wax scale), Chionaspis spp. (scales), Chrysomphalus spp. (scales), Coccus spp. (scales), Dysaphis plantaginea (rosy apple aphid), Empoasca spp. (leafhoppers), Eriosoma lanigerum (woolly apple aphid), Icerya purchasi (cottony cushion scale), Idioscopus nitidulus (mango leafhopper), Laodelphax striatellus (smaller brown planthopper), Lepidosaphes spp., Macrosiphum spp., Macrosiphum euphorbiae (potato aphid), Macrosiphum granarium (English grain aphid), Macrosiphum rosae (rose aphid), Macrosteles quadrilineatus (aster leafhopper), Mahanarva frimbiolata, Metopolophium dirhodum (rose grain aphid), Mictis longicornis, Myzus persicae (green peach aphid), Nephotettix spp. (leafhoppers), Nephotettix cinctipes (green leafhopper), Nilaparvata lugens (brown planthopper), Parlatoria pergandii (chaff scale), Parlatoria ziziphi (ebony scale), Peregrinus maidis (corn delphacid),. Petition 870260058041, dated 15 / 06 / 2026, p. 25 / 116 18 / 51 Philaenus spp. (spittlebugs), Phylloxera vitifoliae (grape phylloxera), Physokermes piceae (spruce bud scale), Planococcus spp. (mealybugs), Pseudococcus spp. (mealybugs), Pseudococcus brevipes (pine apple mealybug), Quadraspidiotus perniciosus (San Jose scale), Rhapalosiphum spp. (aphids), Rhapalosiphum maida (corn leaf aphid), Rhapalosiphum padi (oat bird-cherry aphid), Saissetia spp. (scales), Saissetia oleae (black scale), Schizaphis graminum (greenbug), Sitobion avenae (English grain aphid), Sogatella furcifera (whitebacked planthopper), Therioaphis spp. (aphids), Toumeyella spp. (scales), Toxoptera spp. (aphids), Trialeurodes spp. (whiteflies), Trialeurodes vaporariorum (greenhouse whitefly), Trialeurodes abutiloneus (banded wing whitefly), Unaspis spp. (scales), Unaspis yanonensis (arrowhead scale) from Zulia entreriana.

[0068] In yet another embodiment, the pest insects of the order Lepidoptera, such as Achoea janata, Adoxophyes spp., Adoxophyes orana, Agrotis spp. (worms), Agrotis ipsilon (black cutworm), Alabama argillacea (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navel orangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia gemmatalis (velvetbean caterpillar), Archips argyrospila (fruittree leafroller), Archips rosana (pink leafroller), Argyrotaenia spp. (tortricid moths), Argyrotaenia citrine (orange torrid), Autograph gamma, Bongos crunodes, Bourbon cinnabar (rice leaf folder), Bucculatrix thurberiella (cotton leafperforator), Caloptilia spp. (leaf miners), Capua reticulana, Carposina niponensis (peach fruit moth), Chilo spp., Chlumetia transversa (mango shoot borer), Choristoneura Petition 870260058041, dated 06 / 15 / 2026, p. 26 / 116 19 / 51 rosaceana (obllquebanded leaffroller), Chrysodeixis spp., Cnaphalocerus medinalis (grass leaffroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (Sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borers), Diatraea spp. (stalk borer), Diatraea saccharalis (sugarcane borer), Diatraea graniosella (southwestern corn borer), Earias spp. (bollworms), Earias insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella (almond moth), Ephestia elutella (tobacco moth), Ephestia kuehniella (Mediterranean flour moth), Epimeces spp., Epinotia aporema, Erionota thrax (banana skipper), Eupoecilia ambiguella (grape berry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemborers), Grapholita nuisance (oriental fruit moth), Hedylepta indicata (bean leaf webber), Helicoverpa spp. (noctuid moths), Helicover's armigera (cotton bollworm), Helicover's zea (bollworm / corn earworm), Heliothis spp. (noctuid moths), Heliothis virescens (tobacco budworm), Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella (tomato pinworm), Leucinodes orbonalis (eggplant fruit borer), Leucoptera malifoliella, Lithocollectis spp., Lobesia botrana (grape fruit moth), Loxagrotis spp. (noctuid moths), Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil. Petition 870260058041, 06 / 15 / 2026, p. 27 / 1 20 / 51 palm bagworm), Malacosoma spp. (tent caterpillars), Mamestra brassicae (cabbage armyworm), Maruca testulalis (bean pod borer), Metisa plana (bagworm), Mythimna unipuncta (true armyworm), Neoleucinodes elegantalis (small tomato borer), Nymphula depunctalis (rice caseworm), Operophthera brumata (winter moth), Ostrinia nubilalis (European corn borer), Oxydia vesulia, Pandemis cerasana (common currant tortrix), Pandemis heparana (brown apple tortrix), Papilio demodocus, Pectinophora gossypiella (pink bollworm), Peridroma spp. (cutworms), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp. (leafminers), Pieris rapae (imported cabbageworm), Plathypena scabra, Plodia interpunctella (Indian meal moth), Plutella xylostella (diamondback moth), Polychrosis viteana (grape berry moth), Prays endocarpa, Prays oleae (olive moth), Pseudaletia spp.(noctuid moths), Pseudaletia unipunctata (armyworm), Pseudoplusia includens (soybean looper), Rachiplusia nu, Scirpophaga incertulas, Sesamia spp. (stemborers), Sesamia inferens (pink rice stem borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp. (armyworms), Spodoptera exigua (beet armyworm), Spodoptera fugiperda (fall armyworm), Spodoptera littoralis (cotton leafworm), Spodoptera oridania (southern armyworm), Synanthedon spp. (root borers), Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothes moth), Trichoplusia ni (cabbage looper), Tuta absoluta, Yponomeuta spp., Zeuzera coffeae (red branch borer) e Zeuzera pyrina (leopard moth). Petição 870260058041, de 15 / 06 / 2026, pág. 28 / 116 21 / 51

[0069] In yet another embodiment, the pest insects are of the order Orthoptera, such as Anabrus simplex (Mormon cricket), Gryllotalpidae (mole crickets), Locusta migratoria, Melanoplus spp. (grasshoppers), Microcentrum retinerve (angular-winged katydid), Pterophylla spp. (kaydids), Chistocerca gregaria, Scudderia furcata (forktailed bush katydid) and Valanga nigricorni.

[0070] In yet another embodiment, the pest insects are of the order Thysanoptera, such as Frankliniella fusca (tobacco thrips), Frankliniella occidentalis (western flower thrips), Frankliniella shultzei Frankliniella williamsi (corn thrips), Heliothrips haemorrhaidalis (greenhouse thrips), Riphiphorothrips cruentatus, Scirtothrips spp., Scirtothrips citri (citrus thrips), Scirtothrips dorsalis (yellow tea thrips), Taeniothrips rhopalantennalis and Thrips spp.

[0071] Mites can be, for example, two-spotted spider mite (Tetranychus urticae), European red mite (Panonychus ulmi), Citrus red mite (Panonychus citri), false rust mite (Aceria anthocoptes), false rust mite (Citrus Flat mite) (Brevipalpus lewisi), false two-spotted mite (Brevipalpus phoenicis), yellow mite (Lorryia formosa), brown mite (Bryobia rubrioculus), silver and peach mite (Aculus cornutus), two-spotted spider mite (Tetranychus urticae Koch).

[0072] Mollusks can be, for example, grey garden slug (Deroceras reticulatum), Spanish slug (Arion vulgaris), yellow slug (Limax flavus), tree slug (Limax marginatus), Spanish stealth slug (Arion flagellus), common garden slug (Arion distinctus), common keel slug (Tandonia budapestensis), large red slug and slug Petition 870260058041, dated 06 / 15 / 2026, page 29 / 116 22 / 51 black (Arion ater), large grey slug (Limax maximus), Portuguese slug (Arion lusitanicus).

[0073] Application rates for the pesticide compositions of spinetoram and a group A compound can be influenced by many environmental factors. The desired effect can be determined under the actual conditions of use.

[0074] The composition can be applied in various mixtures or combinations of spinetoram and a compound from group A, for example, in a single “ready-to-use” form, or in a combined spray mixture composed of separate formulations of the single active ingredients, such as a “mix-in-tank” form.

[0075] In certain embodiments, the composition is applied in the form of a ready-to-use formulation comprising spinetoram and a compound from group A. This formulation can be obtained by combining the mixture described in the present invention with an agriculturally active carrier, a surfactant, or other application-enhancing adjuvants routinely employed in formulation technology.

[0076] Compositions comprising (a) spinetoram and (b) a compound from group A may be employed in any conventional form, for example, in the form of a twin package. The compositions may be in the form of, for example, an emulsion concentrate (“EC”), suspension concentrates (“SC”), soluble concentrates (“SL”), suspo-emulsion (“SE”), oil dispersions (“OD”), water-dispersible granules (“WDG or “WG”), water-soluble granules (“SG”) and wettable powders (“WP”). Such compositions may be formulated using agriculturally acceptable carriers, surfactants or Petition 870260058041, dated 06 / 15 / 2026, page 30 / 116 23 / 51 other application-promoting adjuvants commonly used in formulation technology and formulation techniques that are known in the art.

[0077] In one embodiment, the amount of active ingredient or ingredients in the composition is 0.01-99.9 percent by weight (% by weight), specifically 0.1-99% by weight, more specifically 0.1-95% by weight, even more specifically 0.1-90% by weight, based on the total weight of the composition.

[0078] Examples of suitable solid carriers include earthy minerals such as silica gels, silicates, talc, kaolin, attaclay, limestone, lime, chalk, bolus, yellow fertile sediment (loess), clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, sodium carbonate and sodium bicarbonate, and sodium sulfate, synthetic earthy materials, fertilizers such as, for example, ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, and products of plant origin such as cereals, tree bark meal, wood meal and nut shells, cellulose powder and other solid carriers.

[0079] Examples of suitable liquid carriers include water, alcohols such as methanol, cyclohexanol and decanol, ethylene glycol and polypropylene glycol, N,N-dimethylformamide, dimethyl sulfoxide, N-alkylpyrrolidone, aromatic hydrocarbons such as alkylbenzene and alkylnaphthalenes, paraffins, olive, castor, linseed, tung, sesame, corn, peanut, cottonseed, succulent, rapeseed and coconut oils, fatty acid esters, ketones such as cyclohexanone, 2-heptanone, isophorone and 4-hydroxy-4-methyl-2-pentanone and the like. Petition 870260058041, dated 06 / 15 / 2026, page 31 / 116 24 / 51

[0080] The term surfactant as used herein means an agriculturally acceptable material that imparts emulsibility, stability, spreadability, wetting, dispersibility or other surface-modifying properties. Examples of suitable surfactants include nonionic, anionic, cationic and ampholytic types such as lignin sulfonates, fatty acid sulfonates (e.g., lauryl sulfonate), phosphate esters such as alkoxylated alcohol phosphate esters, alkylphenol alkoxylate phosphate esters and styrylphenol ethoxylate phosphate esters, sulfonated naphthalene condensates and naphthalene derivatives with naphthalene formaldehyde condensates or naphthalenesulfonic acid with phenol and formaldehyde, alkylaryl sulfonates, ethoxylated alkylphenols and aryl-phenols, polyalkylene glycols and ethoxylated fatty alcohol.

[0081] Other ingredients, such as wetting agents, adhesives, thickeners, binders, fertilizers or antifreeze agents, may also be added to the composition, including the combination of spinetoram and a compound from group A, in order to increase the stability, density and viscosity of the composition.

[0082] In one embodiment, the combined amount of spinetoram and a compound from group A together with the ready-to-use formulations (compositions) is 0.1-99% by weight.

[0083] In one embodiment, the combined amount of spinetoram and a compound from group A together with the ready-to-use formulations is 0.1-95% by weight.

[0084] In another embodiment, the amount of spinetoram and a compound from group A together in the ready-to-use formulations (compositions) is 10-4-99% by weight, 10-3-99% by weight, or 10-2 Petition 870260058041, dated 06 / 15 / 2026, page 32 / 116 25 / 51 99% by weight. In a specific embodiment, the amount of spinetoram and a compound from group A together with the ready-to-use formulations (compositions) is 10-5-10% by weight, 10-5-1% by weight, 10-5-0.1% by weight, 10-4-10% by weight, 10-4-5% by weight, 10-4-2% by weight, 10-4-1% by weight, 10-4-0.5% by weight, or 10-4-0.1% by weight.

[0085] The remaining components in the formulation are, for example, the vehicle and additives. In the specific embodiment, the vehicle is water-based.

[0086] According to a further aspect, a kit is provided comprising (a) at least one container containing spinetoram; (b) at least one container containing a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof; and (c) instructions for applying said spinetoram and said group A compound to a plague or a site where plague control is desired.

[0087] In one embodiment, spinetoram and the group A compound are applied concomitantly or sequentially.

[0088] Further according to a further aspect, a kit comprising (a) at least one container containing (i) spinetoram; and (ii) a group A compound selected from novaluron, pyriproxyfen, tau-fluvalinate, and a combination thereof; and (b) instructions for applying said spinetoram and said group A compound to a pest or a site where pest control is desired.

[0089] Instructions can be in the form of printed material, for example, as inserts or labels.

[0090] A synergistic effect exists if the action of a combination of the active components is greater than the sum of the actions. Petition 870260058041, dated 06 / 15 / 2026, p. 33 / 116 26 / 51 of each component alone. Therefore, a synergistically effective amount (or an effective amount of a synergistic composition or combination) is an amount that exhibits greater pesticidal activity than the sum of the pesticidal activities of the components individually.

[0091] In the field of agriculture, the term synergy is often understood as defined by Colby SR in an article entitled Calculating synergistic and antagonistic responses of herbicide combinations, published in the journal Weeds, 1967, 15, pages 20-22, incorporated here by reference in its entirety. The expected action for a given combination of two active components can be calculated as follows: E = X + Y — XY 100

[0092] Where E represents the expected percentage of pesticide control for the combination of two pesticides at defined doses (e.g., equal to axey respectively), X is the percentage of pesticide control observed by spinetoram at a defined dose (equal to ax) and Y is the percentage of pesticide control observed by a compound from group A at a defined dose (equal to ay). When the percentage of pesticide control observed by the combination is greater than the expected percentage, a synergistic effect exists.

[0093] It is appreciated that spinetoram and the compound of group A, described in the invention in a particular aspect, can be characterized by various features, for example, weight proportions, application rates, etc., described in the present invention in other aspects.

[0094] It is appreciated that one or more characteristics, Petition 870260058041, dated 06 / 15 / 2026, page 34 / 116 27 / 51 aspects, or embodiments of the present invention, can be combined with one or more other features, aspects, or embodiments of the present invention.

[0095] It is recognized that all embodiments of the invention, including those specifically described for different aspects of the invention, can be combined with any other embodiments of the invention as appropriate. EXAMPLES Example 1 - Novaluron and Spinetoram in the control of Plutella xylostella in cabbage (Brassica oleracea L. vari. Capitta) and broccoli (Brassica oleracea L. vari. Italica).

[0096] Two trials – one in cabbage crops and one in broccoli crops – were conducted in the La Plata district (Buenos Aires, Argentina) to evaluate the efficacy and interaction between foliar applications of Novaluron and Spinetoram in controlling Plutella. For the preparation of the mixtures, Spinetoram (Dlegate® 250 g ai / Kg WG, Dopw AgroSciences LLC) and Novaluron (Rimon® Supra 100 g ai / Litro SC, Makhteshim AGan Group Company) were used. For each treatment, in Examples 1-6, the determined quantity of the formulated products was diluted with water to obtain a mixture.

[0097] Applications were made using a backpack sprayer fitted with a wide 2.1 m boom with nozzles spaced 0.525 m apart, fitted with 8002 flat tips. In all cases, applications were made from 5 pm to 7 pm at a rate of 150 l.ha-1 (liters / ha).

[0098] Ten-meter-long plots were used, each divided into four beds. Applications were made only in three of the beds. A buffer zone of Petition 870260058041, dated 06 / 15 / 2026, page 35 / 116 A large spacing of 28 / 51 was left between the plots to minimize deviation. The experimental design consisted of randomized blocks in four replicates.

[0099] The following evaluation 1, 3, and 7 days after application was presented in Table B below. The larvae per plant (LP) averaged 10 plants per plot. 4 replicates were measured. The % control efficacy in Examples 1-6 was calculated based on the untreated control evaluated on the same day. Table A. Description of each Screening Location | Phenological Stage | Application Rate (L / ha) | Screening 1 | Los Hornos (La Plata) | Vegetative | 150 L / ha | Screening 2 | Etcheverry (La Plata) | Vegetative | 150 L / ha Petition 870260058041, dated 06 / 15 / 2026, p. 36 / 116 29 / 51 Table B: Results Screening 1 - Broccoli % Control Efficacy Amount of Novaluron ai(*), g / ha Amount of Spinetoram ai g / ha 1 DAA 3 DAA 7 DAA 1 Novaluron + Spinetoram 7.5 7.5 92.35% 100.00% 100.00% 2 Novaluron + Spinetoram 7.5 5.625 86.47% 100.00% 100.00% 3 Novaluron + Spinetoram 7.5 3.75 83.53% 96.88% 93.02% 4 Novaluron + Spinetoram 7.5 1.875 64.71% 78.13% 100.00% 5 Novaluron + Spinetoram 5.625 7.5 92.35% 98.13% 93.02% 6 Novaluron + Spinetoram 5, 625 5, 625 79.41% 100.00% 93.02% 7 Novaluron + Spinetoram 5, 625 3, 75 70.59% 98.13% 100.00% 8 Novaluron + Spinetoram 5, 625 1, 875 57.06% 93.75% 100.00% 9 Novaluron + Spinetoram 3, 75 7.5 85.29% 100.00% 100.00% 10 Novaluron + Spinetoram 3, 75 5, 625 80.59% 91.88% 93.02% 11 Novaluron + Spinetoram 3, 75 3, 75 61.76% 87.50% 88.37% 12 Novaluron + Spinetoram 3.75 1.875 54.12% 75.00% 93.02% 13 Novaluron + Spinetoram 1.875 7.5 65.88% 84.38% 65.12% 14 Novaluron + Spinetoram 1, 875 5, 625 64.71% 76.25% 93.02% 15 Novaluron + Spinetoram 1, 875 3, 75 68.82% 60.63% 76,74% 16 Novaluron + Spinetoram 1, 875 1, 875 41.18% 65.63% 76, 74% 17 Novaluron 7.5 0 47.06% 59.38% 88.37% 18 Spinetoram 0 7.5 85.29% 95.00% 88.37%, Petition 870260058041, dated 06 / 15 / 2026, page 37 / 116 30 / 51 19 Novaluron 5.625 0 60.00% 50.00% 88.37% 20 Spinetoram 0 5.625 62.94% 82.50% 81.40% 21 Novaluron 3.75 0 60.00% 53.13% 76.74% 22 Spinetoram 0 3.75 62.94% 84.38% 93.02% 23 Novaluron 1.875 0 50.00% 35.63% 81.40% 24 Spinetoram 0 1.875 41.18% 54.38% 46.51% 25 Untreated control (UTC) 0 0 0.00% 0.00% 0. 00% (*) In this table and the tables below, the term ai refers to the active ingredient. Petition 870260058041, dated 06 / 15 / 2026, page 38 / 116 31 / 51 Sorting 2 - Cabbage % Control Efficacy Amount of Novaluron ai, g / ha Amount of Spinetoram ai, g / ha 1 DAA 3 DAA 7 DAA 1 Novaluron + Spinetoram 7.5 7.5 94.30% 100.00% 100.00% 2 Novaluron + Spinetoram 7.5 5.625 87.45% 100.00% 100.00% 3 Novaluron + Spinetoram 7.5 3.75 86.69% 95.24% 97.46% 4 Novaluron + Spinetoram 7.5 1.875 69.58% 83.33% 95.76% 5 Novaluron + Spinetoram 5.625 7.5 88.59% 98.57% 100.00% 6 Novaluron + Spinetoram 5, 625 5, 625 85.55% 96.19% 100.00% 7 Novaluron + Spinetoram 5, 625 3, 75 74.14% 88.10% 88.98% 8 Novaluron + Spinetoram 5, 625 1, 875 75.29% 83.33% 88.98% 9 Novaluron + Spinetoram 3.75 7.5 77.95% 93.81% 100.00% 10 Novaluron + Spinetoram 3.75 5, 625 80.99% 85.71% 93.22% 11 Novaluron + Spinetoram 3.75 3.75 77.95% 81.90% 88.98% 12 Novaluron + Spinetoram 3.75 1.875 61.98% 73.81% 70.34% 13 Novaluron + Spinetoram 1.875 7.5 77.95% 85.71% 87.29% 14 Novaluron + Spinetoram 1.875 5.625 71.48% 80.95% 83.05% 15 Novaluron + Spinetoram 1.875 3.75 68.44% 74.76% 72.03% 16 Novaluron + Spinetoram 1.875 1.875 62.74% 52.38% 55.08% 17 Novaluron 7.5 0 55.13% 57.14% 42.37% 18 Spinetoram 0 7.5 85.55% 73.81% 87.29% 19 Novaluron 5, 625 0 70.34% 52.38% 59.32% 20 Spinetoram 0 5, 625 72.24% 78.57% 100.00% 21 Novaluron 3, 75 0 60.84% ​​57.14% 32.20%. Petition 870260058041, dated 06 / 15 / 2026, page 39 / 116 32 / 51 22 Spinetoram 0 3.75 58.94% 66.67% 95.76% 23 Novaluron 1.875 0 63.88% 58.10% 847% 24 Spinetoram 0 1.875 67.68% 59.52% 83.05% 25 Untreated controls (UTC) 0 0 0.00% 0.00% 0.00% Example 2 - Novaluron and Spinetoram in the control of fall armyworm (Spodoptera frugiperda) in sweet corn (Zea mays var. saccharata)

[0100] Two trials were conducted in sweet maize crops in the Orán district (Salta, Argentina) with the aim of evaluating the efficacy and interaction of foliar applications of Novaluron and Spinetoram on fall armyworms (Spodoptera frugiperda). The preparation of the mixtures of the products used is as described in Example 1.

[0101] Applications were made using a modular sprayer fitted with a wide 2.1 m boom with nozzles spaced 0.525 m apart, using 8002 flat tips. In all cases, applications were made between 6.00 p.m. and 7.00 p.m. at a rate of 250 l.ha-1'.

[0102] Ten-meter-long plots were used, each divided into four beds. Applications were made only in three of the beds. A large buffer zone was left between the beds to minimize deviation. The experimental design consisted of randomized blocks in four replicates.

[0103] The evaluation followed by 1, 3, and 7 days after application is presented in Table B below. The larvae per plant (LP) averaged 10 plants per plot (4 replicates were measured). The % control efficacy is the same as described in Example 1. Petition 870260058041, dated 06 / 15 / 2026, page 40 / 116 33 / 51 Table A Description of each Screening Location | Phenological State | Application Rate (l / ha) | Screening 1 | Rio Blanco (Oran, Salta) | V 5 | 205 l / ha | Screening 2 | Las Yungas (Oran, Salta) | V 5 | 205 l / ha Petition 870260058041, dated 06 / 15 / 2026, page 41 / 116 34 / 51 Table B Results Screening 1% Effectiveness (according to the number of larvae / plant) % Control Efficacy Amount of Novaluron (g / ha) Amount of Spinetoram (g / ha) 1 DAA 3 DAA 7 DAA 1 Novaluron + Spinetoram 7.5 7.5 97.78% 100.00% 100.00% 2 Novaluron + Spinetoram 7.5 5.625 95.56% 100.00% 100.00% 3 Novaluron + Spinetoram 7.5 3.75 95.56% 100.00% 100.00% 4 Novaluron + Spinetoram 7.5 1.875 82.22% 96.97% 100.00% 5 Novaluron + Spinetoram 5.625 7.5 100.00% 98.48% 100.00% 6 Novaluron + Spinetoram 5, 625 5, 625 100.00% 96.97% 97.01% 7 Novaluron + Spinetoram 5, 625 3, 75 88.89% 96.97% 98.51% 8 Novaluron + Spinetoram 5, 625 1, 875 93.33% 95.45% 92.54% 9 Novaluron + Spinetoram 3, 75 7.5 84.44% 93.94% 91.04% 10 Novaluron + Spinetoram 3, 75 5, 625 68.89% 90.91% 86.57% 11 Novaluron + Spinetoram 3.75 3.75 64.44% 90.91% 83.58% 12 Novaluron + Spinetoram 3.75 1.875 57.78% 80.30% 85.07% 13 Novaluron + Spinetoram 1.875 7.5 55.56% 80.30% 80.60% 14 Novaluron + Spinetoram 1, 875 5, 625 51.11% 77.27% 68.66% 15 Novaluron + Spinetoram 1, 875 3, 75 42.22% 65.15% 64,18% 16 Novaluron + Spinetoram 1, 875 1, 875 31.11% 74.24% 52.24% 17 Novaluron 7.5 0 77.78% 93.94% 83.58%, Petition 870260058041, dated 06 / 15 / 2026, page 42 / 116 35 / 51 18 Spinetoram 0 7.5 77.78% 96.97% 89.55% 19 Novaluron 5.625 0 66.67% 89.39% 76.12% 20 Spinetoram 0 5.625 71.11% 84.85% 76.12% 21 Novaluron 3.75 0 51.11% 78.79% 65.67% 22 Spinetoram 0 3.75 64.44% 78.79% 59.70% 23 Novaluron 1.875 0 35.56% 63.64% 46.27% 24 Spinetoram 0 1.875 44.44% 62.12% 50.75% 25 Untreated Controls (UTC) 0 0 0.00% 0.00% 0.00% Petition 870260058041, dated 06 / 15 / 2026, page 43 / 116 36 / 51 Screening 2% Effectiveness (according to the number of larvae / plant) % Control Efficacy Amount of Novaluron (g / ha) Amount of Spinetoram (g / ha) 1 DAA 3 DAA 7 DAA 1 Novaluron + Spinetoram 7.5 7.5 68.42% 92.45% 100.00% 2 Novaluron + Spinetoram 7.5 5.625 68.42% 84.91% 100.00% 3 Novaluron + Spinetoram 7.5 3.75 62.28% 94.34% 98.28% 4 Novaluron + Spinetoram 7.5 1.875 60.53% 86.79% 93.10% 5 Novaluron + Spinetoram 5.625 7.5 63.16% 92.45% 100.00% 6 Novaluron + Spinetoram 5, 625 5, 625 63.16% 94.34% 98.28% 7 Novaluron + Spinetoram 5, 625 3, 75 50.00% 84.91% 98.28% 8 Novaluron + Spinetoram 5, 625 1, 875 55.26% 81.13% 87.93% 9 Novaluron + Spinetoram 3.75 7.5 65.79% 83.02% 94.83% 10 Novaluron + Spinetoram 3.75 5.625 50.00% 81.13% 89.66% 11 Novaluron + Spinetoram 3.75 3, 75 47.37% 84.91% 84.48% 12 Novaluron + Spinetoram 3.75 1.875 42.11% 71.70% 70.69% 13 Novaluron + Spinetoram 1.875 7.5 44.74% 73.58% 75.86% 14 Novaluron + Spinetoram 1.875 5, 625 47.37% 69.81% 7586% 15 Novaluron + Spinetoram 1, 875 3, 75 34.21% 62,26% 5690% 16 Novaluron + Spinetoram 1, 875 1, 875 31.58% 49.06% 53.45% 17 Novaluron 7.5 0 55.26% 71.70% 82.76% 18 Spinetoram 0 7.5 44.74% 71.70% 84.48% 19 Novaluron 5,625 0 42.11% 64.15% 70.69% 20 Spinetoram 0 5,625 55.26% 71.70% 82.76%, Petition 870260058041, dated 06 / 15 / 2026, page 44 / 116 37 / 51 21 Novaluron 3.75 0 26.32% 58.49% 62.07% 22 Spinetoram 0 3.75 31.58% 64.15% 72.41% 23 Novaluron 1.875 0 28.95% 49.06% 60.34% 24 Spinetoram 0 1.875 15.79% 45.28% 65.52% 25 Untreated controls (UTC) 0 0 0.00% 0.00% 0.00% Example 3 - Foliar applications of pyriproxyfen and spinetoram in the control of whitefly (Trialeurodes vaporariorum) in peppers (Capsicum annuum):

[0104] The efficacy of pyriproxyfen and spinetoram in controlling whitefly in pepper crops was evaluated.

[0105] Two trials were conducted in pepper crops in the plant growth belt in La Plata (Buenos Aires Province, Argentina) with the aim of evaluating the efficacy and interaction of pyriproxyfen and spinetoram applications on whiteflies. For the preparation of the mixtures, the spinetoram product used is the same as in Example 1, pyriproxyfen (EPINGLE® 100g ai / L EC, Sumitomo Chemical Co., Ltd.) was used.

[0106] Applications were made using a backpack sprayer equipped with a vertical boom and a constant pressure regulator, with nozzles spaced 0.30 m apart and fitted with 8002 flat tips. In all cases, applications were made at a rate of 900-915 l.ha-1 (L / ha).

[0107] Plots of eight meters in length were used, each divided into four plots (eight rows of plants). Applications were made only in two plots, while the two remaining plots were left as buffers. The experimental design consisted of randomized blocks in four replicates.

[0108] The number of adult whiteflies per leaf was Petition 870260058041, dated 06 / 15 / 2026, page 45 / 116 38 / 51 evaluated, for example, on days 1, 3, 5, 7, 10, and 14 after application, while the number of whitefly nymphs per leaf was evaluated, for example, on days 10, 14, 21, and 29 after application. For this evaluation, ten leaves were taken from the plant located in the central rows of each plot, taking care to avoid the initial and final meter of each plot. The control effectiveness (%) was calculated based on the untreated control. Description of each screening Location | Phenological State | Application Rate (l.ha-1) | Screening 1 | Jurado (Olmos) | Harvest 900 liters / ha | Screening 2 | Expovictor (Florencio Varela) | Harvest 915 liters / ha Petition 870260058041, dated 06 / 15 / 2026, page 46 / 116 39 / 51 Results - Screening 1 Control effectiveness (%) Spinetoram ai amount, g / ha Pyriproxyfen ai amount, g / ha Adults Nymphs 1 DAA 3 DAA 5 DAA 7 DAA 10 DAA 14 DAA 10 DAA 14 DAA 21 DAA 2 50% 74.76 .1 60 70.26% 77.57% 68.79% 81.74% 100.00% 94.82% 100.00% 96.08% 2 60.0 75 67.57% 78.89% 77.59.0% 71.061% 93.06% 100.00% 96.85% 3 60.0 50 53.20% 66.32% 61.25% 45.42% 55.13% 66.88% 100.00% 65.53% 096.606 46.51% 54.34% 52.24% 29.72% 45.56% 57.75% 93.42% 82.82% 96.49% 98.43% 5 45.0 100 61.31% 76.086% 75.37% 93.42% 94.82% 100.00% 98.43% 6 45.0 75 57.33% 67.37% 65.86% 57.38% 56.72% 59.026% 59.743% 45.0 50 48.08% 57.93% 56.01% 49.72% 52.62% 50.96% 70.99% 62.01% 72.52% 95.28% 8 45.0 25% 43.29% 5 35.76% 39.28% 74.27% 36.23% 89.67% 90.55% 9 30.0 100 53.20% 67.66% 66.28% 77.57% 61.051% 682.58% 7 98.43% 10 30.0 75 48.65% 64.52% 61.25% 70.84% ​​46.01% 58.17% 90.33% 58.59% 89.67% 59.06% 11 50.06%97% 48.35% 43.65% 48.04% 33.49% 56.05% 80.66% 62.11% 62.19% 96.06% 12 30.0 25 29.59% 42.81% 41.14% 31.96% 26.42% 42.04% 83.75% 43.06% 72.52% 88.98% 13 15.0 100 53.49% 64.67% 63.55% 82.43% 56.95% 71.97% 83.75% 67.29% 86.36% 85.04% 14 15.0 75 40.54% 42.07% 51.40% 58.69% 41.69% 47.98% 77.37% 48.34% -10.33% 59.85% 15 15.0 50 36.98% 41.92% 34.44% 45.61% 31.44% 39.28% 83.95% 62.01% 89.67% 85.04% 16 15.0 25 33.85% 39.97% 33.39% 23.36% 21.64% 31.85% 83.75% 63.77% 82.85% 93.70% 17 60.0 0 32.15% 44.76% 54.96% 55.14% 35.54% 42.68% 54.74% 51.66% 37.40% 74.79% 18 0.0 100 43.53% 63.02% 63.55% 69.35% 56.95% 45.65% 67.89% 51.76% 69.01% 88.19% 19 15.0 0 10.10% 15.27% 0.71% 9.16% -16.17% -14.65% 61.32% 8.59% -3.31% 61.41% 20 0.0 25 19.20% 30.09% 25.01% 36.64% 18.91% 9.55% 54.74% 24.12% 58.68% 73.25% 21 45.0 0 20.34% 29.19% 32.76% 31.96% 23.46% 12.95% 45.26% 41.30% 30.99% 74.00% 22 0.0 75 19.91% 55.84% 47.84% 64.49% 45.56% 35.46% 48.55% 46.48% 62.19% 87.40% 23 30.0 0 34.00% 38.62% 8.67% 37.57% 21.64% 5.94% 74.08% 17.18% 10.74% 78.73% 24 0.0 50 34.00% 55.69% 39.04% 57.01% 33.71% 29.51% 80.85% 51.66% 38.02% 90.57% 25 0.0 0 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%. 39 / 51 Petition 870260058041, dated 06 / 15 / 2026, page 47 / 116 40 / 51 Screening 2 Control effectiveness (%) Adults Nymphs ai Spina g / ha ai Pirb g / ha 1 DAA 3 DAA 6 DAA 8 DAA 11 DAA 17 DAA 22 DAA 30 DAA 1 60.0 100 67.01% 80.58% 797.82% 97.28% 83.39% 97.51% 2 60.0 75 52.82% 69.70% 58.33% 61.64% 85.09% 81.85% 68.94% 82.61% 3 580% 60.0% 60.5% 53.22% 41.74% 61.14% 35.24% 73.50% 4 60.0 25 32.76% 54.87% 39.52% 38.83% 68.58% 71.20% 15.047% 6 66.72% 66.10% 67.44% 61.42% 86.24% 82.26% 66.07% 82.73% 6 45.0 75 57.13% 62.36% 53.75% 58.651% 78.651% 7 78.80% 7 45.0 50 54.61% 54.45% 52.20% 40.66% 64.22% 64.19% 55.91% 72.88% 8 45.0 25 42.42% 8 % 36.54 66.42% −0.48% 68.77% 9 30.0 100 66.86% 65.96% 66.13% 68.84% 80.28% 72.36% 63.68% 70.64% 10.495 30.40 57.26% 60.67% 84.17% 70.96% 58.78% 72.26% 11 30.0 50 50.00% 48.02% 44.46% 52.18% 57.11% 40.11% 58.80% 3 25 38.48% 40.32% 42.32% 42.25% 63.53% 43.32% 18.04% 63.97% 13 15.0 100 63.74% 65.18% 65.252% 66. 62.84% 72.94% 14 15,0 75 53.49% 51.98% 49.76% 50.27% 69.50% 60.15% 57.59% 51.00% 15 15.0 50 48.29% 58.19% 45.54% 42.25% 57.11% 39.69% 46.36% 58.85% 16 15.0 25 37.59% 41.03% 33.15% 29.11% 56.65% 48.35% 14.81% 27.56% 17 60.0 0 52.60% 53.18% 42.02% 55.42% 64.22% 61.72% 36.80% 56.92% 18 0.0 100 67.01% 64.97% 64.58% 59.70% 85.32% 70.21% 57.23% 76.43% 19 15.0 0 13.97% 7.63% 10.18% 13.35% 12.16% 27.81% -17.32% 18.89% 20 0.0 25 28.90% 10.24% 15.24% 30.51% 60.09% 37.21% 14.93% 33.29% 21 45.0 0 37.74% 35.24% 24.40% 45.56% 50.00% 39.36% 19.95% 36.10% 22 0.0 75 46.14% 48.23% 33.93% 44.04% 69.27% ​​47.44% 58.30% 58.98% 23 30.0 0 33.51% 19.77% 9.05% 32.24% 44.72% 9.90% -0.72% 45.01% 24 0.0 50 43.39% 31.00% 33.27% 41.17% 61.70% 48.84% 30.11% 41.90% 25 0.0 0 0% 0% 0% 0% 0% 0% 0% 0% 40 / 51 Petition 870260058041, dated 06 / 15 / 2026, p. 48 / 116 41 / 51 Example 4 - Foliar applications of pyriproxyfen and spinetoram in the control of western flower thrips (Frankliniella occidentalis) in peppers (Capsicum annuum).

[0109] The study was conducted to evaluate the efficacy of and the interaction between pyriproxyfen and spinetoram on western flower thrips in pepper crops.

[0110] Two trials were conducted on pepper crops in vegetables growing in the La Plata region (Buenos Aires Province, Argentina), with the aim of evaluating the efficacy and interaction of pyriproxyfen and spinetoram applications on western flower thrips. For the preparation of the mixtures, the product used was the same as in example 3.

[0111] Applications were made using a backpack sprayer equipped with a vertical boom and a constant pressure regulator, with nozzles spaced 0.30 m apart and fitted with 8002 flat tips. In all cases, applications were made at a rate of 790-937 l.ha-1 (L / ha). Eight-meter-long plots were used, each divided into four beds (eight rows of plants). Applications were made only in two beds, while the two remaining beds were left as buffers. The experimental design consisted of randomized blocks in four replications.

[0112] The number of thrips (all stages) per flower was evaluated on days, for example, on days 1, 3, 5, 7, 10, and 14 after application. For this evaluation, ten flowers were taken from plants located in the central rows of each plot, taking care to avoid the initial and final meter of each plot. The control effectiveness (%) was calculated with Petition 870260058041, dated 06 / 15 / 2026, page 49 / 116 42 / 51 based on untreated control. Detailed description of each screening: Location Phenological state Application rate (l.ha-1) Screening 1 Jurado (Olmos) Harvest 937 liters / ha Screening 2 Expovictor (Florencio Varela) Harvest 790 liters / ha Screening 1 Control Efficacy (%) Amount of active ingredient Spinetoram, g / ha Amount of active ingredient Pyriproxyfen, g / ha 1 DAA 3 DAA 5 DAA 7 DAA 10 DAA 14 DAA 1 60.0 100 81.38% 92.21% 95.94% 89.42% 88.59% 77.33% 2 60.0 75 67.02% 80.33% 83.25% 80.77% 78.52% 72.44% 3 60.0 50 62.23% 71.72% 82.74% 75.96% 79.19% 61.33% 4 60.0 25 48.94% 65.16% 76.65% 68.27% 65.77% 53.33% 5 45.0 100 69.15% 71.31% 90.36% 81.73% 83.89% 63.11% 6 45.0 75 43.62% 69.26% 85.28% 73.08% 72.48% 49.33% 7 45.0 50 36.17% 59.02% 78.68% 72.12% 70.47% 42.53% 8 45.0 25 39.89% 59.02% 76.14% 64.42% 59.06% 21.78% 9 30.0 100 73.40% 71.31% 87.31% 64.42% 72.48% 49.24% 10 30.0 75 50.53% 59.02% 71.07% 56.73% 53.69% 36.44% 11 30.0 50 38.30% 48.36% 72.59% 51.92% 55.03% 41.33% 12 30.0 25 35.64% 39.75% 60.91% 37.50% 42.95% 24.44% 13 15.0 100 52.13% 70.12% 80.71% 59.62% 69.13% 47.56% 14 15.0 75 45.21% 47.54% 80.20% 48.08% 54.36% 38.22% 15 15.0 50 23.94% 40.98% 71.57% 40.38% 50.34% 36.89% 16 15.0 25 21.81% 41.39% 62.44% 32.69% 48.32% 28.44% 17 60.0 0 43.62% 70.90% 83.25% 61.54% 65.10% 47.56% 18 0.0 100 22.34% 64.34% 81.73% 57.69% 65.77% 36.44% 19 15.0 0 6.38% 30.33% 41.12% 1.92% 23.49% 23.11% 20 0.0 25 12.77% 28.69% 61.42% 33.65% 34.23% 29.33% 21 45.0 0 30.85% 45.49% 59.39% 53.85% 63.76% 22.22% 22 0.0 75 27.66% 49.18% 63.45% 50.00% 65.77% 42.67% 23 30.0 0 17.55% 41.80% 42.13% 18.27% 32.21% 25.78% 24 0.0 50 40.43% 43.03% 48.73% 47.12% 40.27% 45.78% 25 0.0 0 0% 0% 0% 0% 0% 0% Petition 870260058041, dated 06 / 15 / 2026, page 50 / 116 43 / 51 Screening 2 Control Efficacy (%) Amount of aniotic agent Spinetoram g / ha Amount of aniotic agent Pyriproxyfen g / ha 1 DAA 3 DAA 6 DAA 8 DAA 1 Pyriproxyfen + Spinetoram 60.0 100 73.11% 91.49% 75.10% 72.53% 2 Pyriproxyfen + Spinetoram 60.0 75 61.86% 85.49% 69.22% 67.79% 3 Pyriproxyfen + Spinetoram 60.0 50 58.68% 76.40% 57.16% 52.77% 4 Pyriproxyfen + Spinetoram 60.0 25 50.12% 67.12% 54.90% 55.73% 5 Pyriproxyfen + Spinetoram 45.0 100 78.48% 78.53% 68.14% 63.44% 6 Piriproxyfen + Spinetoram 45.0 75 57.70% 70.60% 61.76% 54.35% 7 Piriproxyfen + Spinetoram 45.0 50 60.15% 62.67% 52.35% 53.56% 8 Piriproxyfen + Spinetoram 45.0 25 53.30% 60.74% 54.61% 52.96% 9 Piriproxyfen + Spinetoram 30.0 100 64.06% 73.69% 65.69% 70.16% 10 Piriproxyfen + Spinetoram 30.0 75 61.12% 61.70% 63.24% 56.72% 11 Piriproxyfen + Spinetoram 30.0 50 45.97% 55.71% 51.67% 50.20% 12 Piriproxyfen + Spinetoram 30.0 25 46.45% 50.48% 50.10% 55.73% 13 Piriproxyfen + Spinetoram 15, 0 100 66.75% 64.60% 64.61% 64.23% 14 Piriproxyfen + Spinetoram 15,0 75 64.30% 62.67% 48.63% 52.96% 15 Piriproxyfen + Spinetoram 15. 0 50 55.01% 47.97% 47.45% 53.95% 16 Piriproxyfen + Spinetoram 15. 0 25 37.65% 52.22% 42.35% 44.66% 17 Spinetoram 60.0 0 55.99% 61.70% 70.88% 62.06% 18 Piriproxyfen 0.0 100 31.30% 47.20% 43.14% 44.86% 19 Spinetoram 15.0 0 30.56% 28.63% 33.04% 16.01% 20 Pyriproxyfen 0.0 25 16.14% 17.79% 19.22% -14.82% 21 Spinetoram 45.0 0 38.14% 43.91% 55.10% 50.40% 22 Pyriproxyfen 0.0 75 35.45% 32.11% 16.08% 32.61% 23 Spinetoram 30.0 0 37.90% 39.85% 39.12% 33.20% 24 Pyriproxyfen 0.0 50 35.70% 22.05% 28.92% 37.55% 25 Untreated controls (UTC) 0 0 0% 0% 0% 0% Petition 870260058041, dated 06 / 15 / 2026, page 51 / 116 44 / 51 Example 5 - Foliar application of tau-fluvalinate and spinetoram on whiteflies (Trialeurodes vaporariorum) in peppers (Capsicum annuum).

[0113] Two trials were conducted on pepper crops in vegetables growing in the La Plata region (Buenos Aires Province, Argentina) with the aim of evaluating the efficacy and interaction of taufluvalinate and spinetoram applications in controlling whiteflies. For the preparation of the mixtures, the spinetoram product used was the same as in Example 1, tau-fluvalinate (Mavrik® 240g ai / L EW, Makhetshim Agan Group Company) was used.

[0114] Applications were made using a backpack sprayer equipped with a vertical boom and a constant pressure regulator, with nozzles spaced 0.30 m apart and fitted with 8002 flat tips. In all cases, applications were made at a rate of 810-900 l.ha-1 (L / ha). Eight-meter-long plots were used, each divided into four beds (eight rows of plants). Applications were made only in two beds, while the two remaining beds were left as buffers. The experimental design consisted of randomized blocks in four replications.

[0115] The number of adult whiteflies per leaf was evaluated, for example, on days 1, 3, 5, 7, 10, and 14 after application, while the number of whitefly nymphs per leaf was evaluated, for example, on days 11, 15, and 21 after application. For this evaluation, ten leaves were taken from plants located in the central rows of each plot, taking care to avoid the initial and final meters of each plot. The control effectiveness (%) was calculated based on Petition 870260058041, dated 06 / 15 / 2026, page 52 / 116 45 / 51 untreated control. Table A Location Phenological state Application rate (l / ha) Screening 1 Serrano (Olmos) Harvest 900 liters / ha Screening 2 Expovictor (Florencio Varela) Harvest 810 liters / ha Petition 870260058041, dated 06 / 15 / 2026, page 53 / 116 46 / 51 Results - Screening 1 Control Efficacy (%) Adults Nymphs Amount of aniotic agent Spinetoram g / ha Amount of aniotic agent Tau-fluvalinate g / ha 1 DAA 3 DAA 5 DAA 7 DAA 10 DAA 14 DAA 11 DAA 15 DAA 21 DAA 1 60.0 30 69.60% 83.64% 76.85% 80.28% 81.09% 65.31% 94.44% 95.28% 71.88% 2 60.0 22.5 61.85% 71.78% 70.85% 68.71% 69.83% 64.25% 76.03% 85.32% 56.05% 3 60.0 15 32.50% 57.10% 51.81% 60.14% 62.73% 60.07% 68.71% 79.87% 64.04% 4 60.0 7.5 -4.78% 41.40% 41.21% 57.89% 61.34% 60.47% 61.41% 78.44% 44.62% 5 45.0 30 66.06% 82.20% 70.08% 72.56% 74.90% 72.75% 78.36% 86.45% 84.08% 6 45.0 22.5 48.09% 70.52% 44.00% 64.92% 68.78% 64.54% 75.44% 55.03% 33.07% 7 45.0 15 7.07% 57.28% 25.52% 49.32% 56.23% 51.44% 65.20% 70.02% 43.19% 8 45.0 7.5 -19.60% 44.16% 13.39% 20.66% 27.84% 36.15% 51.75% 66.53% 26.12% 9 30.0 30 61.85% 74.00% 63.46% 70.63% 74.84% 69.17% 64.04% 87.16% 68.72% 10 30.0 22.5 37.76% 59.20% 46.51% 59.72% 67.25% 66.21% 64.62% 58.62% 55.25% 11 30.0 15 18.07% 32.53% 25.66% 46.42% 57.12% 58.44% 54.39% 68.58% 47.09% 12 30.0 7.5 -153% 20,49% -3,84% 28,34% 41,94% 42,86% 30,12% 56,98% 31,14% 13 15,0 30 65,11% 73,64% 59,83% 68,06% 74,09% 67,14% 61,12% 81,83% 79,26% 14 15,0 22,5 41,30% 55,78% 39,26% 56,25% 65,56% 61,41% 45,91% 69,94% 42,17% 15 15,0 15 4,88% 33,25% 20,01% 37,66% 49,83% 53,44% 51,75% 54,43% 41,59% 16 15,0 7,5 -31,17% 14,44% -3,07% 16,02% 30,87% 38,43% 42,11% 39,02% 18,84% 17 60,0 0 32,31% 45,66% 34,59% 44,96% 45,66% 53,07% 59,36% 83,57% 56,61% 18 0,0 30 44,84% 64,29% 53,84% 57,00% 62,38% 68,81% 68,42% 74,84% 67,17% 19 15,0 0 4, 11% 16,00% 5,23% 29,51% 25,81% 45,30% 40,94% 55,44% 40,58% 20 0,0 7,5 14,05% 39,78% 23,92% 46,84% 52,61% 49,98% 40,64% 62,01% 40,92% 21 45,0 0 14,63% 37,09% 20,15% 40,89% 43,33% 49,90% 41,82% 67,76% 48,99% 22 0,0 22,5 21,32% 49,07% 30,61% 51,52% 62,53% 58,85% 38,30% 69,40% 62,67% 23 30,0 0 -3,25% 21,51% 0,56% 22,62% 31,91% 41,76% 21,92% 54,41% 41,03% 24 0,0 15 14,53% 40,86% 20,78% 39,63% 52,90% 49,00% 47,66% 64,27% 46,97%, 46 / 51 Petition 870260058041, dated 06 / 15 / 2026, page 54 / 116 47 / 51 Screening 2 Control Efficacy (%) Adults Nymphs Amount of adjuvant Spinetoram g / ha Amount of adjuvant Taufluvalinate g / ha 1 DAA 3 DAA 6 DAA 10 DAA 14 DAA 21 DAA 2 8 DAA 1 60.0 72.0 4.38% 72.91% 90.30% 78.32% 76.47% 84.45% 75.95% 2 60.0 54.0 2.92% 58.88% 82.49% 61.70% 46.04% 79.08% 62.78% 3 60.0 36.0 -5.22% 41.51% 73.74% 51.67% 41.43% 73.02% 58.69% 4 60.0 18.0 7.72% 29.05% 55.35% 38.96% 50.12% 58.36% 37.58% 5 45.0 72.0 4.80% 74.39% 76.57% 69.76% 70.85% 83.85% 65.74% 6 45.0 54.0 -0.42% 64.47% 72.19% 60.07% 59.60% 71.30% 44.21% 7 45.0 36.0 4.18% 35.82% 56.03% 34.96% 58.57% 62.08% 31.68% 8 45.0 18.0 4.80% 26.99% 54.81% 36.46% 71.86% 37.14% 6.31% 9 30.0 72.0 10.86% 77.13% 80.40% 70.01% 74.70% 73.15% 55.50% 10 30.0 54.0 1.25% 55.35% 66.33% 56.89% 71.61% 60.92% 48.25% 11 30.0 36.0 -3.13% 50.44% 62.56% 50.77% 58.30% 43.71% 26.24% 12 30.0 18.0 5.64% 49.95% 67.14% 53.14% 66.23% 40.41% 16.48% 13 15.0 72.0 1.46% 81.26% 81.82% 74.98% 58.82% 62.72% 49.16% 14 15.0 54.0 9.81% 63.40% 76.23% 59.58% 57.54% 59.32% 34.62% 15 15.0 36.0 12.11% 49.66% 62.22% 46.70% 54.48% 37.65% 10.62% 16 15.0 18.0 -1.67% 46.91% 55.29% 44.01% 50.13% 39.78% 7.89% 17 60.0 0.0 7.31% 39.74% 54.07% 41.73% 51.92% 46.70% 27.36% 18 0.0 72.0 11.06% 58.88% 71.45% 59.74% 71.10% 73.66% 59.37% 19 15.0 0.0 -6.26% -19.92% 18.92% -1.87% 37.60% 22.78% -21.39% 20 0.0 18.0 3.55% 18.25% 34.61% 7.74% 54.73% 37.55% -17.56% 21 45.0 0.0 -15.45% 31.01% 52.19% 29.83% 57.03% 41.27% 6.48% 22 0.0 54.0 -15.03% 56.82% 64.44% 43.60% 62.67% 58.68% 11.29% 23 30.0 0.0 -14.20% 12.07% 25.32% 18.91% 49.37% 32.44% -15.76% 24 0.0 36.0 1.67% 22.96% 48.35% 10.27% 67.97% 50.50% 1.95% 0.0 0 0% 0% 0% 0% 0% 0% 0% 47 / 51 Petition 870260058041, dated 06 / 15 / 2026, p. 55 / 116 48 / 51 Example 6 - Foliar applications of tau-fluvalinate and spinetoram on western flower thrips (Frankliniella occidentalis) in peppers (Capsicum annuum).

[0116] The study was conducted to evaluate the efficacy of and the interaction between tau-fluvalinate and spinetoram on western flower thrips in pepper crops.

[0117] Two trials were conducted on pepper crops in vegetables growing in the La Plata region (Buenos Aires Province, Argentina), with the aim of evaluating the efficacy and interaction of foliar applications of tau-fluvilinate and spinetoram on western flower thrips.

[0118] Applications were made using a backpack sprayer equipped with a vertical boom and a constant pressure regulator, with nozzles spaced 0.30 m apart and fitted with 8002 flat tips. In all cases, applications were made at a rate of 790-937 l.ha-1 (L / ha). Eight-meter-long plots were used, each divided into four beds (eight rows of plants). Applications were made only in two beds, while the two remaining beds were left as buffers. The experimental design consisted of randomized blocks in four replications.

[0119] The number of thrips (all stages) per flower was evaluated on days, for example, on days 1, 3, 5, 7, 10, and 14 after application. For this evaluation, ten flowers were taken from plants located in the central rows of each plot, taking care to avoid the initial and final meter of each plot. The control effectiveness (%) was calculated based on the untreated control. Petition 870260058041, dated 06 / 15 / 2026, page 56 / 116 49 / 51 Description of each screening: Location Phenological state Application rate (l / ha) Screening 1 Serrano (Olmos) Harvest 937 liters / ha Screening 2 Expovictor (Florencio Varela) Harvest 790 liters / ha Screening 1 Control Efficacy (%) Amount of active ingredient Spinetoram g / ha Amount of active ingredient Taufluvalinate g / ha 1 DAA 3 DAA 5 DAA 7 DAA 10 DAA 14 DAA 1 60.0 72.0 44.33% 86.49% 97.67% 93.91% 90.51% 81.96% 2 60.0 54.0 39.63% 82.14% 87.67% 87.54% 80.09% 76.26% 3 60.0 36.0 27.57% 75.16% 80.00% 79.42% 78.47% 63.24% 4 60.0 18.0 35.61% 64.05% 70.47% 67.83% 73.15% 53.42% 5 45.0 72.0 23.88% 77.78% 86.74% 76.81% 83.80% 77.40% 6 45.0 54.0 39.30% 69.50% 73.72% 74.78% 74.07% 68.49% 7 45.0 36.0 20.52% 59.91% 60.93% 64.35% 69.21% 56.85% 8 45.0 18.0 27.57% 54.90% 55.12% 51.30% 65.74% 48.63% 9 30.0 72.0 39.64% 68.85% 77.91% 81.16% 82.41% 74.20% 10 30.0 54.0 43.00% 60.57% 66.98% 68.99% 71.99% 65.30% 11 30.0 36.0 19.18% 48.80% 58.37% 58.26% 65.28% 55.02% 12 30.0 18.0 38.30% 35.95% 49.77% 42.90% 57.18% 45.89% 13 15.0 72.0 52.72% 71.46% 75.81% 66.67% 72.92% 63.24% 14 15.0 54.0 49.36% 61.87% 65.12% 55.36% 64.81% 55.71% 15 15.0 36.0 43.33% 54.03% 50.47% 57.10% 57.87% 39.04% 16 15.0 18.0 24.14% 45.53% 35.81% 42.32% 53.47% 38.81% 17 60.0 0.0 68.61% 72.98% 66.28% 54.78% 56.25% 48.17% 18 0.0 72.0 67.81% 66.01% 68.84% 60.87% 64.81% 36.76% 19 15.0 0.0 51.31% 57.52% 53.49% 40.87% 40.05% 36.30% 20 0.0 18.0 36.42% 29.41% 40.23% 25.22% 39.81% 38.58% 21 45, 0 0,0 53.92% 59.69% 58.84% 43.48% 46.30% 34.25% 22 0,0 54.0 56.54% 62.53% 59.30% 46.38% 51.39% 37.21% 23 30.0 0,0 51.71% 51.42% 50.47% 37.68% 42.82% 28.77% 24 0,0 36, 0 46.28% 55.34% 55.35% 44.64% 42.13% 26.94% Petition 870260058041, dated 06 / 15 / 2026, page 57 / 116 50 / 51 Screening 2 Control Efficacy (%) Amount of Spinetoram ai g / ha Amount of Tau-fluvalinate ai g / ha 1 DAA 3 DAA 5 DAA 10 DAA 16 DAA 1 60.0 72.0 95.81% 96.26% 93.61% 96.23% 42.74% 2 60.0 54.0 90.35% 89.69% 89.23% 91.21% 43.79% 3 60.0 36.0 74.85% 79.28% 73.49% 79.39% 32.88% 4 60.0 18.0 55.65% 51.00% 53.73% 64.33% 27.64% 5 45.0 72.0 95.13% 92.30% 94.79% 94.87% 41.90% 6 45.0 54.0 79.14% 81.09% 78.22% 82.11% 40.64% 7 45.0 36.0 62.38% 66.14% 60.83% 67.57% 37.08% 8 45.0 18.0 46.00% 49.04% 46.51% 53.56% 28.27% 9 30.0 72.0 79.59% 80.86% 79.64% 80.65% 38.76% 10 30.0 54.0 73.20% 77.69% 74.44% 79.71% 38.13% 11 30.0 36.0 48.15% 52.32% 53.73% 61.19% 33.30% 12 30.0 18.0 42.20% 44.17% 48.40% 53.45% 30.16% 13 15.0 72.0 66.28% 65.23% 61.42% 59.73% 35.19% 14 15.0 54.0 61.70% 60.36% 52.66% 57.11% 30.58% 15 15.0 36.0 46.59% 50.06% 40.36% 44.04% 41.06% 16 15.0 18.0 30.12% 31.60% 28.28% 33.58% 30.37% 17 60.0 0.0 71.25% 73.84% 72.66% 77.41% 35.61% 18 0.0 72.0 43.18% 53.34% 51.48% 55.86% 33.93% 19 15.0 0.0 23.20% 38.17% 37.16% 42.05% 41.06% 20 0.0 18.0 -0.88% 20.16% 14.44% 22.70% 23.44% 21 45.0 0.0 60.82% 57.87% 62.72% 66.84% 29.11% 22 0.0 54.0 31.58% 43.37% 45.56% 48.54% 30.37% 23 30.0 0.0 51.27% 46.21% 53.49% 56.80% 26.38% 24 0, 0 36, 0 19.59% 39.75% 32.43% 38.91% 33.72% Phytotoxicity

[0120] No symptoms were observed in any of the treatments in Examples 1-6. Conclusion:

[0121] The results show very good pest control efficacy with a combination of spinetoram and the co-component (Novaluron, Pyriproxyfen, Tau-fluvalinate). Petition 870260058041, dated 06 / 15 / 2026, page 58 / 116 51 / 51 Additionally, these combinations provide very good control over those pests that tend to be present on plants at the same time.

[0122] Although this invention has been illustrated and demonstrated with reference to preferred embodiments thereof, it should be understood by those skilled in the art that many alternatives, modifications and variations may be made thereto without departing from the spirit and scope of protection of the invention. Consequently, it is intended to cover all such alterations, modifications and variations which are within the spirit and broad scope of protection of the appended claims.

[0123] All publications, patents, and patent applications mentioned in this descriptive report are incorporated herein in their entirety by reference within the report to the same extent that each individual publication, patent, or patent application was specifically and individually indicated to be incorporated herein by reference.

Claims

1. Pesticide mixture, characterized in that it comprises: (a) spinetoram; and (b) a group A compound selected from novaluron or taufluvalinate, wherein: the weight ratio of spinetoram to the group A compound is 1:10 to 10:

1.

2. Pesticide mixture, according to claim 1, characterized in that the application rate of spinetoram is 1 g / ha to 500 g / ha.

3. Pesticide mixture, according to claim 1, characterized in that the application rate of the compound from group A is 1 g / ha to 500 g / ha.

4. Pesticide mixture, according to any one of claims 1 to 3, characterized by being in an effective synergistic quantity.

5. Pesticide composition, characterized in that it comprises the pesticide mixture, as defined in any one of claims 1 to 4; and an agriculturally acceptable carrier.

6. Pesticide composition, according to claim 5, characterized by being used to control pests in a crop or a site thereof.

7. Method for controlling pests in a crop, characterized in that it comprises: contacting the pests or the site where pest control is desired with a pesticide mixture comprising: (a) spinetoram; and (b) a compound of group A selected from novaluron or taufluvalinate, wherein the weight ratio of spinetoram to the compound of group A is 1:10 to 10:

1. Petition 870260058041, dated 15 / 06 / 2026, p. 60 / 116 2 / 2 8. Method, according to claim 7, characterized in that the application rate of spinetoram is 1 g / ha for 500 g / ha.

9. Method according to claim 7, characterized in that the application rate of the compound from group A is 1 g / ha for 500 g / ha.

10. Method, according to any one of claims 7 to 9, characterized in that the application rate of the pesticide mixture is 1 g / ha for 1000 g / ha.

11. Method, according to any one of claims 7 to 10, characterized in that spinetoram and the group A compound are applied concomitantly or sequentially.