Fragrance-Intensifying Compositions
Steviol-based glycosides are used as fragrance fixatives to extend fragrance longevity and reduce compound usage without altering fragrance character, addressing the lack of effective fixatives that maintain aroma integrity.
Patent Information
- Application Number
- BR112021025470
- Authority / Receiving Office
- BR · BR
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-06-20
- Filing Date
- 2020-06-19
- Publication Date
- 2026-07-28
- Estimated Expiration
- 2040-06-19
AI Technical Summary
There is a shortage of potent and effective fragrance fixatives that do not interfere with the intended aroma, and natural fixatives can distort the character of the fragrance.
Incorporating steviol-based glycosides, such as steviol glycosides and glycosylated steviol glycosides, into fragrance compositions to act as fixatives, which enhance fragrance longevity without altering the fragrance character.
Steviol-based glycosides increase fragrance longevity by up to 8-48 hours and reduce the amount of fragrance compounds needed, while maintaining the perceived fragrance quality.
Abstract
Description
"Intensifying Compositions of FRAGRANCE" Cross-reference to related requests
[0001] This application claims the benefit of priority to U.S. Provisional Application 62 / 863,901, entitled “FRAGRANCE-ENHANCING COMPOSITIONS”, filed June 20, 2018, the disclosure of which is incorporated in the present invention in its entirety. BACKGROUND
[0002] A fragrance is a mixture of individual components, both aromatic and non-aromatic. Each fragrance component interacts with other components in the mixture, and with the chemical and structural nature of the environment to determine the aesthetic and physical characteristics of the final system. The combined talents of the perfumer and technical staff, working closely together, are necessary to create a fragrance blend that will provide a top note, a heart note, and a base note. The top note is characterized by the refreshing quality felt early on when the fragrance is applied, while the base note is the aroma that continues and lingers for a long time with the wearer. The heart note is what unites both the top note and the base note, providing a pleasant transition from the top note to the base note.
[0003] One of the components used in fragrance blends is called a fixative and is generally used to prolong the fragrance effect of the fragrance blend by slowing the evaporation rate of volatile materials in the fragrance blend. This is achieved through hydrogen bonding of the fixative component with the other components, resulting in a lower overall vapor pressure for the fragrance blend. A good fixative will generally not be odorous on its own, will be miscible in both polar and non-polar solvents, and will have a higher boiling point than the other components in the fragrance blend. Typical examples of fixatives are Petition 870210116931, dated 12 / 16 / 2021, pages 82 / 122 2 / 36 botanical and floral absolutes, oil concretes and resins, animal secretions and extracts, macrocyclic musks and nitro musks.
[0004] It is well known that fragrance fixatives (also called fragrance carriers) are generally synthetically produced chemicals and that natural ones can distort the nature or character of the fragrance being fixative.
[0005] Despite advances in fragrance research, there is still a shortage of compounds that are both potent and effective fragrance fixatives without interfering with the intended aroma. These needs and others are met by the present disclosure. SUMMARY
[0006] The embodiments of the present disclosure provide compositions including glycosides, products including glycosides and the like.
[0007] One embodiment of the present disclosure includes fragrance compositions comprising at least one fragrance compound and a glycoside. The glycoside may be selected from a steviol glycoside, a glycosylated steviol glycoside, a derivative of a steviol glycoside, a derivative of a glycosylated steviol glycoside, or combinations thereof.
[0008] One embodiment of the present disclosure also includes products including a fragrance composition as above. The products may include a perfume, an eau de toilette, a lotion, a soap, a cosmetic, a body care product, a dishwashing detergent, a surface cleaning agent, an air freshener, a fabric softener, a bleach or a laundry detergent.
[0009] One embodiment of the present disclosure also includes a non-edible product comprising a perfume, the perfume comprising water, a solvent, a glycoside and a fragrance compound. Petition 870210116931, dated 12 / 16 / 2021, pp. 83 / 122 3 / 36
[0010] Other compositions, apparatus, methods, aspects and advantages will or will become apparent to a person skilled in the art after examination of the following drawings and detailed description. It is intended that all such additional compositions, apparatus, methods, aspects and advantages are included in the present description, are encompassed within the scope of the present disclosure and are protected by the appended claims. DETAILED DESCRIPTION
[0011] Before the present disclosure is described in greater detail, it should be understood that this disclosure is not limited to the particular embodiments described, and as such may, of course, vary. It should also be understood that the terminology used in the present invention is for the purpose of describing only specific embodiments, and is not intended to be limiting, since the scope of the present disclosure will be limited only by the appended claims.
[0012] Where a range of values is provided, it is understood that each intermediate value, down to the tenth of a unit of the lower limit unless the context clearly determines otherwise, between the upper and lower limits of that range and any other mentioned or intermediate value in that mentioned range, is covered by the disclosure. The upper and lower limits of those smaller ranges may independently be included in the smaller ranges and are also covered by the disclosure, subject to any limit specifically excluded in the mentioned range. Where the mentioned range includes one or both limits, the ranges excluding either or both of those included limits are also included by the disclosure.
[0013] Unless otherwise defined, all technical and scientific terms used in the present invention have the same meaning as commonly understood by a person with common knowledge of the art to which this disclosure pertains. Although any methods and materials similar or equivalent to those described in this invention Petition 870210116931, dated 12 / 16 / 2021, pp. 84 / 122 4 / 36 can also be used in the practice or testing of the present revelation; the preferred methods and materials are now described.
[0014] As will be evident to those skilled in the art after reading this disclosure, each of the individual embodiments described and illustrated in the present invention has distinct components and aspects that can be easily separated from or combined with aspects of any of the other various embodiments without departing from the scope or spirit of the present disclosure. Any method cited can be carried out in the order of events cited or in any other order that is logically possible.
[0015] Unless otherwise indicated, the methods of this disclosure will employ chemical and similar techniques which are included within the knowledge of the art.
[0016] The following examples are presented in order to provide those with common skill in the art with a complete disclosure and description of how to perform the methods and use the compositions and methods disclosed and claimed in the present invention. Efforts have been made to ensure accuracy with respect to numbers (e.g., quantities, temperature, etc.), however some errors and deviations should be considered. Unless otherwise indicated, parts are parts by weight, temperature is in °C, and pressure is at or near atmospheric. Standard temperature and pressure are defined as 20°C and 1 atmosphere.
[0017] Before the embodiments of the present disclosure are described in detail, it should be understood that, unless otherwise indicated, the present disclosure is not limited to particular materials, reagents, reaction materials, manufacturing processes, or the like, as these may vary. It should also be understood that the terminology used in the present invention is for the purpose of describing specific embodiments only, and is not intended to be limiting. It is also possible in the present disclosure that steps may be performed in a different sequence where this is logically feasible. Petition 870210116931, dated 12 / 16 / 2021, pp. 85 / 122 5 / 36
[0018] It should be noted that, as used in the descriptive report and the attached claims, the singular forms “a”, “an” and “the” include plural referents unless the context clearly indicates otherwise.
[0019] As used in the present invention, the following terms have the meanings assigned to them unless otherwise specified. In this disclosure, “essentially consisting of” or “essentially consists of” or similar terms, when applied to methods and compositions covered by the present disclosure, refers to compositions such as those disclosed in the present invention, but which may contain additional structural groups, composition components, or method steps (or analogous or derived versions thereof as discussed above). Such additional structural groups, composition components, or method steps, etc., however, do not materially affect the basic and novel characteristic(s) of the compositions or methods, compared with those of the corresponding compositions or methods disclosed in the present invention."Essentially consisting of" or "consists essentially of" or similar, when applied to methods and composition covered by the present disclosure, have the meaning ascribed to them in United States Patent Law, and the term is unlimited, allowing for the presence of more than is cited, provided that basic or new features of what is cited are not altered by the presence of more than is cited, but excludes prior art embodiments. DEFINITIONS
[0020] A “fragrance compound” as used in the present invention, also known as an odorant, aroma, or fragrance, is a chemical compound that has a smell or odor and is sufficiently volatile to be carried to the olfactory system in the upper part of the nose. “Aromatic,” as used in the present invention, refers to a characteristic of being an odorant. Aromatics can be derived from plant sources (such as bark, fruits, flowers, resins, etc.), animal sources Petition 870210116931, dated 12 / 16 / 2021, pages 86 / 122 6 / 36 (such as honey, musk, castoreum, etc.), other natural sources (such as lichen, algae, etc.) or synthetic sources.
[0021] Rebaudioside A 80% has Rebaudioside A as the main component at least 80% and the other glycosides at 80% on a dry basis. Similarly, Rebaudioside A 97% has Rebaudioside A as the main component at a minimum of 97% with the remainder being other glycosides on a dry basis.
[0022] “Glycosylation” as used in the present invention describes the number of glucose molecules attached to steviol glycosides. A low degree of glycosylation may include from one to five glucose molecules. A high degree of glycosylation may include from five to twenty glucose molecules.
[0023] “Alcohols”, as used in the present invention, may include, but are not limited to, terpene alcohols (e.g., linalool, citronellol, geraniol, nerol, terpineol, α-terpineol, dihydromyrcenol, farnesol, nerolidol, cedrol, menthol, and borneol), aromatic alcohols (e.g., phenyl ethyl alcohol, benzyl alcohol, dimethyl benzyl carbinol, phenyl ethyl dimethyl carbinol, and phenyl hexanol), and aliphatic alcohols (e.g., cis-3-hexenol, 1-(2,2,6-trimethylcyclohexyl)-3-hexanol, Amber Core (Trade name of Kao Corporation), 1-(2-tert-butylcyclohexyloxy)-2-butanol), Sandalmysore Core (Trade name of Kao Corporation), 2-methyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol), Magnol (Trade name of Kao Corporation, a mixture containing, as its main component, 3(4)-(5-ethylbicyclo[2.2.1]heptyl-2)-cyclohexanol), Undecavertol (trade name of Givaudan Roure KK, 4-methyl-3-deceno-5-ol), and isobornylcyclohexanol).
[0024] As used in this invention, the phrase “natural high potency sweetener” (or “NHP sweetener” or “NHPS”) means any sweetener found in nature that may be in raw, extracted, purified or any other form, singularly or in combination thereof and characteristically has a sweetness potency greater than Petition 870210116931, dated 12 / 16 / 2021, pp. 87 / 122 7 / 36 sucrose, fructose, or glucose, yet still have fewer calories. Non-limiting examples of NHPSs include: Rebaudioside A, Rebaudioside B, Rebaudioside C, Rebaudioside D, Rebaudioside E, Rebaudioside F, Dulcoside A, Dulcoside B, rubusoside, stevia, stevioside, other components of steviol glycoside extract, mogroside II, mogroside III, mogroside IV, mogroside V, mogroside VI, isomogroside V, 11oxomogroside, siamenoside, Luo Han Guo sweetener, other components of Luo Han Guo extract, monatin and its salts (monatin SS, RR, RS, SR), curculin, glycyrrhizic acid and its salts, thaumatin, monellin, mabinlin, brazzein, hernandulcin, phyllodulcin, glycyphyllin, phloridzin, trilobatin, baiyunoside, osladin, polypodoside A, pterocaryoside A, Pterocaryoside B, mukurozioside, phlomisoside I, periandrin I, abrusoside A, cyclocaryoside I, and modifications or derivatives thereof. NHPS also includes modified NHPSs. Modified NHPSs may include NHPSs that have been altered naturally or synthetically.For example, a modified NHPS includes NHPSs that have been fermented, contacted with an enzyme, or derived from or substituted for NHPS. For the sake of brevity in the embodiment description, a modified NHPS is not expressly described as an alternative to unmodified NHPSs, but it should be understood that modified NHPSs can be substituted for NHPSs in any embodiment disclosed in the present invention.
[0025] “Perfume” as used in the present invention describes a product generally used as a topically applied fragrance, which can be applied as a spray or directly to the skin. Perfume may also include cologne, eau de toilette, eau de parfum, aftershave, or similar products as would be understood by a person with common skill in the art. In one aspect, perfume does not include edible products containing fragrance. In another aspect, perfume is not edible. In yet another embodiment, perfume is not intended to be edible. Petition 870210116931, dated 12 / 16 / 2021, pages 88 / 122 8 / 36
[0026] “Edible”, as used in the present invention, refers to products that are fit to be eaten and / or generally intended to be ingested (e.g., food or beverages). Similarly, “non-edible” refers to products not intended for oral consumption (e.g., body products, household cleaning products, fine fragrance products). Such non-edible products may be non-toxic if ingested, but are not typically understood to be food or beverages. GENERAL DISCUSSION
[0027] According to the purpose(s) of the present disclosure, as incorporated and extensively described in the present invention, the embodiments of the present disclosure, in some respects, relate to fragrance compositions and products including fragrance compositions.
[0028] In general, embodiments of the present disclosure provide fragrance compositions including at least one fragrance compound as well as a glycoside. According to the embodiments disclosed, the glycoside may comprise one or more steviol-based glycosides including steviol glycosides, glycosylated steviol glycosides, derivatives of a steviol glycoside, derivatives of a glycosylated steviol glycoside, or combinations thereof.
[0029] Advantageously, the addition of a glycoside provides increased fragrance longevity. Steviol-based glycosides have been extensively tested and are known to be safe for humans.
[0030] The use of steviol glycosides, glycosylated steviol glycosides and their derivatives as a fixative in a fragrance product markedly increases the lasting power of the fragrance. The increased lasting power does not distort the character of the fragrance. In other words, the perceived fragrance of a fragrance composition comprising the glycoside is substantially equal to the perceived fragrance of Petition 870210116931, dated 12 / 16 / 2021, pp. 89 / 122 9 / 36 a similar fragrance composition that does not have the glycoside component. These properties give it a unique and unexpected character of a steviol-based glycoside.
[0031] According to various embodiments of the present disclosure, the fragrance composition comprises from about 0.001 to about 5% by weight, or from about 0.01 to about 3%, or from about 0.10 to about 1% of the glycoside, based on the total weight of the fragrance composition. Advantageously, the inclusion of a steviol-based glycoside in a fragrance composition can extend the time during which a fragrance is perceptible, from about 8 hours to 48 hours longer than compositions without the steviol-based glycoside. In some embodiments, the fragrance composition including the glycoside may allow a reduction in the amount of fragrance compound (e.g., from about 10% to 30% less) needed in a composition to provide the same perceived fragrance. Such benefits can reduce the cost of manufacturing products that include fragrance, such as perfumes, cosmetics, and household products.Advantageously, the inclusion of steviol-based glycoside can simultaneously reduce the amount of fragrance compound needed to detect a fragrance and increase the duration for which the fragrance can be detected.
[0032] In various embodiments, the glycoside may include diterpins (e.g., ubusoside, Rebaudioside A, Rebaudioside B, Rebaudioside C, Rebaudioside D, Rebaudioside E, Rebaudioside F, Rebaudioside M, Rebaudioside N, Rebaudioside O, Dulcoside A, or enzymatically treated stevia extract). The inclusion of steviol-based glycoside does not interfere with the perceived fragrance of a composition. It is anticipated that other high-potency natural sweeteners and / or their derivatives may be used, including, but not limited to, triterpins (e.g., monkfruit) and glycyrrhizin (e.g., licorice root extract).
[0033] Glycosylated steviol glycoside may have a low degree of glycosylation, where the number of glucose molecules linked Petition 870210116931, dated 12 / 16 / 2021, pages 90 / 122 10 / 36 to steviol glycosides is one to five. Alternatively, glycosylated steviol glycoside may have a high degree of glycosylation, where the number of glucose molecules attached to steviol glycosides is six to twenty.
[0034] Steviol glycosides, glycosylated steviol glycosides, and their derivatives of the present disclosure can be extracted from the plant Stevia rebaudiana bertoni. The extraction process is well established. According to one process, the plant leaves are soaked in water for several hours, resulting in an aqueous solution that is rich in glycosides. The aqueous solution can then be processed through a series of filtration steps to remove undesirable components. Finally, the aqueous solution is lyophilized, resulting in a white-yellowish powder. For glycosylated steviol glycosides, this white-yellowish powder is further dissolved in water and processed with enzymes after adjusting the pH and temperature along with a carbohydrate source (e.g., amide or dextrins). The derivatives are produced, generally by reacting chemicals with Stevia extract.There are no known examples of using steviol glycosides, glycosylated steviol glycosides, or their derivatives as a fixative in fragrance products.
[0035] The addition of an effective amount of steviol-based glycosides to fragrance mixtures resulted in fragrance fixation without detectably altering the fragrance of the mixtures. Neither steviol glycosides, glycosylated steviol glycosides, nor their derivatives have a detectable fragrance, so their use as fragrance fixative or fragrance-enhancing components in non-food or topical applications has not been recognized to date.
[0036] While not intending to be limited by theory, it is hypothesized that steviol-based glycosides are nanoencapsulating the less soluble fragrance compounds in the mixture, allowing them to evaporate more slowly, thereby prolonging the availability of the fragrance. Petition 870210116931, dated 12 / 16 / 2021, pp. 91 / 122 11 / 36
[0037] Interesting effects of steviol glycosides have been shown in other fields such as pharmaceuticals, including increasing the absorption of insoluble or poorly soluble bioactive materials. Low water solubility of bioactive compounds, resulting in their use in very high concentrations to provide a desired pharmacological effect, is problematic and results in negative drug side effects among subjects. Surfactants can be used, in part, to increase the solubility / bioavailability of bioactive compounds to target cells and reduce overstimulation of non-target cells accidentally exposed during medical treatment.High-temperature sonication and high-temperature, high-pressure homogenization of aqueous solutions of steviol glycoside surfactant and bioactive compounds are two techniques shown to further stabilize the systems to the point where they are resistant to changes in pH and temperature and remain intact after drying and reconstitution.
[0038] According to various embodiments of the present disclosure, fragrance compounds may be any ingredient or combination of ingredients providing an odor to the fragrance composition or to an object or product to which it is provided. Fragrance compounds may be natural, synthetic, or a combination thereof.Fragrance compounds may include essential oils and extracts (e.g., castoreum, costus root oil, oakmoss absolute, geranium oil, jasmine absolute, patchouli oil, rose oil, sandalwood oil, ylang-ylang oil), alcohols (e.g., citronellol, Ebanol™, eugenol, geraniol, Super Muguet™, linalool, phenyl ethyl alcohol, Sandalore™, terpineol, or Timberol™), aldehydes and ketones (e.g., Azurone™, α-amyl cinnamaldehyde, Georgywood™, hydroxycitronellal, Iso E Super™, Isoraldeine™, Hedione™, maltol, methyl cedryl ketone, methyl ionone, or vanillin), ethers, and acetals (e.g., for example, Ambrox™, methyl geranyl ether, rose oxide or Spirambrene™;), esters and lactones (for example, benzyl acetate, cedryl acetate, γ-decalactone,). Petition 870210116931, dated 12 / 16 / 2021, pp. 92 / 122 12 / 36 Helvetolide™, Serenolide™, γ-undecalactone or vetivenyl acetate), macrocycles (e.g., ambrettolide, ethylene brassylate or Exaltolide™), and heterocycles (e.g., isobutylquinoline).
[0039] Other fragrance compounds, also called perfume raw materials, may include, but are not limited to, ethyl 2,4-decadienoate, amyl heptoate, amyl acetate, ethyl butyrate, grapefruit zest (C&A), prenyl acetate, pinoacetaldehyde, 2,6-nonadienol, 3,6-nonadienol, cis-6-nonenol, excital, ebanol, polysantol, orange juice carbonyls, lemon juice carbonyls, orange sinensal, paradiff, tangerine, benzaldehyde, mandarin aldehyde, undecalactone, norlimbanol, decyl aldehyde, trans-2-hexenal, trans-2-decenal, damascenone, 2-isobutylthiazole, 4-methyl-4-mercaptopentan-2-one, corps cassis 0.1% TEC, patchouli, 2-methoxy-4-vinylphenol, pridine acetyl 10%, sulfurol, diacetyl, furanoeol, maple lactone, amyl allyl glycolate, Ambroxan, alpha damascone damascene, Cetalox, cyclal C, Cedramber, cycle galbanate, Galbex, Cymal, nerol, Florhydral, Ptbucinal, iso citral cycle, Fructone, methyl iso butenyl tetrahydro pyran, Frutene, Delphone, ethyl methyl phenyl glycidate, Violiff, para acetate, Delta damascone damascene, Ambrox, Calone, iso eugenol, Hivemal, methyl beta naphthyl ketone, Ozonyl, benzyl salicylate, Spirogalbone, cinnamic alcohol, Javanol, dihydro iso jasmonate, Adoxal, Kharismal, pyrazines, ethyl anthranilate, supra aldehyde, Bacdanol, Anethol, irisantheme, yara, Keone, cis 3 hexenyl salicylate, methyl nonyl ketone, coumarin, gamma dodecalactone, Applinate, eucalyptol, intreleven aldehyde, heliotropin, indole, Manzanato, ionone, alpha, trans 4 decennial, ionone beta, Oxane, neobutanone, Clonal, methyl octine carbonate, Floralozone, methyl heptine carbonate, methyl nonyl acetaldehyde, Cashmeran, phenoxy ethyl isobutyrate, phenyl acetaldehyde, ethyl methyl phenyl glycidate, undecyl aldehyde, Aurantiol, nectaryl, buccoxime, lauryl aldehyde, nirvanol, Trifemal, pyrazobutyl, Veloutone, anisic aldehyde, paramenthene, isovaleraldehyde 0.1% DPG, liminal, labienoxime, rhubofix, iso propil quinolina, 4-(2,6,6-Trimetil-1-cyclohexenil)-3-butenona-2; (3aR(3aalfa,5abeta,9aalfa,9bbeta))-dodecaidro-3a,6,6,9a-tetrametil nafta(2,1. Petition: 870210116931, December 16, 2021, page. 93 / 122 13 / 36 b) furan; 2,6-Dimethyl-5-heptenal; 3,7-Dimethyl-1,6-octadien-3-ol; 3-Methyl-2-buten-1-yl acetate; 3,7-Dimethyl-2,6-octadienenitrile; 2,4-Dimethylcyclohexene-3-carbaldehyde; Phenyl Acetaldehyde, Indole, Ethyl Methyl Dioxolane Acetate; 4-(2,6,6-Trimethyl-1,3-cyclohexadienyl)-3-buten-4-one; Cis-3 Hexenyl Acetate; Lauric Acid, Tricyclodecenyl Acetate, Para-Cresyl Methyl Ether, 7-acetyl, 1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethylnaphthalene; 3-buten-2-one; 3-methyl-4(2,6,6-trimethyl-2-cyclohexen-1-yl); acetic acid (Cyclohexyloxy), 2-propenyl ester; 3-buten-2-one, 4-(2,6,6-trimethyl-2-cyclohexen-1-yl), (E); Decyl Aldehyde, Methyl-3,4-dioxy(cyclocoacetonyl)benzene; 2,6-Dimethyl-2,6-octadien-8-ol; ortho tertiary butylcyclohexanyl acetate; hexanoic acid, 2-propenyl ester; 4-Methoxybenzaldehyde; 3-(3-Isopropylphenyl)butanal; Iso 2-Methoxy-4-(2-propenyl)phenol, Tetrahydro 3,7-Dimethyl-1,6-octadien-3-ol; 1-methyl-4-isopropenyl-1-cyclohexene; Methyl phenyl carbonyl acetate; galaxolide;Hexahydro-4,7methano1H-inden-5 (or 6)-yl propionate; Benzaldehyde, 3,7-Dimethyl-2,6-octadienal; 3,3Dimethyl-5-(2,2,3-trimethyl-3-cycloentene-1-yl)-4-penten-2-ol; 2-Methoxy-4-(2propenyl)phenol; 3,7-dimethyl-6-octen-1-ol; allyl heptanoate; 1,3-Oxathiane, 2methyl-4-propyl-, cis-; paradiff; (all-E)-alpha-sinensal, 2,6,10-trimethyl2(E),6(E),9(E),11-dodecatetraenal; mandarin aldehyde, pI-menthen-8 thiol; 4-Methyl3-decene-5-ol; Ethyl caproate, Ethyl-2-4-decadienoate, 4-Penten-1-one, 1-(5,5Dimethyl-1-cyclohexen-1-yl)-; 1H-Indenene-a-propanal, 2,3-dihydro-1,1-dimethyl-(9CI); Methyl nonyl acetaldehyde; Orange juice carbonyls; 4 dozen; 3cyclohexene-1-carboxaldehyde, 2,4-dimethyl; 2,6,-nonenol; 2,6-nonadeinal; 2,6nonadienol; 3-P-cumenyl-propionaldehyde 4-(1-methylethyl)-benzenopropanal; 1(2,6,6-Trimethyl-1,3-cyclo-hexanedienyl)-2-butene-1-one; 6-(Z,3-pentenyl)-tetrahydro(2H)-pyranone-2; 3-Methyl-(cis-2-penten-1-yl)-2-cyclopenten-1-one. 2.6 nonenol; 2,6-nonadienol;(3aR-(3aalfa,5abeta,9aalfa,9bbeta))-dodecaido-3a,6,6,9atetramethyl nafta(2,1-b)furano; Beta Gamma Hexenol; Cis 3 hexenyl acetate; 3P-cumenil-propionaldeido 4-(1-methylethyl)-benzenepropanal; 1-(2,6,6-Trimethyl-1,3cyclo-hexadienil)-2-buten-1-ona; 3-(3-Isopropylphenyl)butanal; 4-Penten-1-ona,1-(5,5-Dimetil-1-cyclo-hexen-1-il)-; 1H-Indeno-a-propanal,2,3-diidro-1,1-dimethyl; Petition 870210116931, of 16 / 12 / 2021, p. 94 / 122 14 / 36 (9CI); 4-(2,6,6-Trimetil-1-ciclo-hexenil)-3-butenona-2; 6-(Z,3-pentenil)-tetraidro(2H)-piranona-2; 2,6-Dimetil-5-heptenal; 6,6-Dimetilbiciclo{3.1.1)Hept-2-eno-2proponal; 3-ciclo-hexeno-1-carboxaldeído, 2,4-dimetil; 4-Metil-3-decen-5-ol; orto terciário acetato de butil ciclo-hexanila; 3-Metil-(cis-2-penten-1-il)-2-cyclopenten1-ona; 4-Penteno-2-ol,3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-il)-. Benzaldehyde; Undeclactone; 4-(2,6,6-Trimethyl-1-cyclohexenil)-3-butenone-2; Allyl heptanoate; 1,3-Oxathiane, 2-methyl-4-propyl-, cis-; Paradiff, (all-E)-alphasinensal, 2,6,10-trimethyl-2(E),6(E),9(E),11-dodecatetraenal; mandarin aldehyde; 4-dodecenal; p-1-menten-8-thiol; Orange juice carbonyls; Decyl aldehyde; 4-Methyl-3-decen-5-ol; 4-Penten-1-one, 1-(5,5-Dimethyl-1-cyclohexen-1-yl)-. Hexanoic acid, 2-propenyl ester; 4-Methoxybenzaldehyde; Allyl heptanoate; Benzaldehyde; 1,3-Oxathiane, 2-methyl-4-propyl-, cis-; Decyl aldehyde; Ethyl 2'4decadienoate; Ethyl caproate; 4-Penten-1-one, Dimethyl-1-cyclohexen-1-yl)-; p1-menten-8 thiol; (all-E)-alpha-sinensal 2,6,10-trimethyl-2(E),6(E),9(E),11dodecatetraenal; IH-Indene-a-propanal, 2,3-dihydro-1,1-dimethyl-(9C1); 4-(2,6,6Trimethyl-1-cyclohexenyl)-3-butenone-2; 3 twelve-yearly; Methyl Nonyl Acetaldehyde; Orange juice carbonyls; Paradiff; 4 twelve-yearly; 3-cyclohexene-1carboxaldehyde, 2,4-dimethyl; 4-Methyl-3-decen-5-ol; animal fragrances such as musk oil, civet, castoreum, ambergris;Plant fragrances such as nutmeg extract, cardamom extract, ginger extract, cinnamon extract, patchouli oil, geranium oil, orange oil, mandarin oil, orange blossom extract, cedarwood, vetiver, lavandin, ylang-ylang extract, tuberose extract, sandalwood oil, bergamot oil, rosemary oil, peppermint oil, lemon oil, lavender oil, citronella oil, chamomile oil, clove oil, sage oil, neroli oil, labdanum oil, eucalyptus oil, verbena oil, mimosa extract, narcissus extract, carrot seed extract, jasmine extract, frankincense extract, rose extract, acetophenone, adoxal, C-12 aldehyde, C-14 aldehyde, C-18 aldehyde, allyl caprylate, heptanoate allyl, ambroxan, dimethylindan derivatives, anethole, anisaldehyde, benzaldehyde, benzyl acetate, benzyl alcohol and; Petition 870210116931, dated 12 / 16 / 2021, pages 95 / 122 15 / 36 ester derivatives, benzyl propionate, benzyl salicylate, beta gamma hexanol, borneol, butyl acetate, camphor, carbitol, carvone, cetalox, cinnamaldehyde, cinnamyl acetate, cinnamyl alcohol cis-3-hexanol and ester derivatives, cis-3-hexenyl methyl carbonate, cis jasmone, citral, citronnelol and ester derivatives, cumin aldehyde, cyclamen aldehyde, galbanate cycle, damascones, decanol, decyl aldehyde, spoilole, delta muscenone, dihydromyrcenol, dimethyl benzyl carbinol, 6,8-dimethyl-2-nonanol, dimethyl benzyl carbinyl butyrate, ethyl isobutyrate, ethyl propionate, ethyl caprylate, ethyl cinnamate, hexanoate ethyl, ethyl valerate, exaltolide, fenchone, galaxolide, geraniol and ester derivatives, hedione, helional, 2-heptonone, hexenol, hexyl salicylate, hydroxycitronelal, ionones, isoeugenol, isoamyl isovalerate, iso E super, linalool acetate, lilial, lyral, majantol, mayol, menthol, p-methylacetophenone, methyl cedrylone, methyl dihydrojasmonate,methyl eugenol, mugetanol, para-hydroxyphenylbutanone, phenoxyinol, dimethyl phenylacetaldehyde acetate, phenoxyethyl isobutyrate, phenyl ethyl alcohol, pinenes, sandalwood, sanjinol, santalol, thymol, terpenes, tonalide, 3,3,5-trimethylcyclohexanol, undecylenic aldehyde, phenyl ethyl alcohol, linalool, geraniol, citronellol, cinnamic alcohol, isobornyl acetate, benzyl acetate, para-tertiary butylcyclohexyl acetate, linalyl acetate, dihydronordicyclopentadienyl acetate, dihydronordicyclopentadienyl propionate, amyl salicylate, benzyl salicylate, alpha-octyl hydrocinnamic para-isopropyl aldehyde, hexyl cinnamic aldehyde, hydroxycitronellal, heliotropin, anisaldehyde, citral, dextrolimonene, coumarin, gamma methyl ionone, methyl beta naphthyl ketone, gamma undecalactone, eugenol, musk xylene, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-gamma-2-benzopyran, 4-acetyl-6-tertiary butyl-1,1-dimethylindane, 6-acetyl-1,1,3,4,4,6-hexamethyl tetrahydro naphthalene, beta naphthyl ethyl ether, methyl eugenol, methyl cedrenyl ketone, patchouli, lavandin, geranyl nitrile, alpha ionone, alpha beta ionone, benzyl iso eugenol, cinnamic amyl aldehyde, beta gamma hexenol, orange CP, orthotertiary-butyl cyclohexyl acetate, 2-methyl-3-(paraiso-propylphenyl)propionaldehyde, trichloro methyl phenyl carbinyl acetate, nonane diol1,3-acetate, methyl dihydro jasmonate, phenoxy ethyl iso butyrate, citronella, citronellal, Petition 870210116931, dated 12 / 16 / 2021, pp. 96 / 122 16 / 36 citratal, tetrahydromuguol, ethylene brassylate, almond cetona, almiscar tibetina, ethyl phenyl acetate, carvalho musgo 25%, hexila salicylate, eucalyptol, Stemone, Cashmeran, GERANIOL, citronela nitrile, Linalool, Ethyl linalool, Benzyl acetate, Undecavertol, Methyl Phenyl Carbinyl Acetate, 6Nonen-1-ol, (6Z)-, Benzyl Propionate, Iso-E Super, 2,6-Nonadien-1-ol, (2E,6Z)-(10% Nonadienol em DPG), cis-3-Hexen-1-ol (beta gama hexenol), Isobomila Acetate, Ambrox DL, propanal de ozônio (Floralozone), 3-metil-5(2,2,3-tnmetil-3-ciclopenten-1-il)pent-4-en-2-ol (Ebanol), isobutirato de fenetil, Florhydral, álcool de fenil ethyla, bourgeonal, gama-Undecalactona (racêmico), Diidromircenol, Etil 2-metil-1,3-dioxolane-2-acetato (Fructone),óxido de Bigarade, propionato de cicloexil alila, Tetraidrolinalool (Tetraidro Linalool), Trimofix O, Citronellol, Neofolione, mistura de Hivernal, acetato de Linalila, Citroneliloxiacetaldeído, Delta-Muscenone, Romanolide, beta-Pineno, Karanal, Vertenex, acetato de o-terc-Butylciclohexila (verdox), Nectarila, gamaDecalactone, Isoeugenol, Heliotropin, Oxalone (Calone 1951), aldeído cinamico, Diidro-beta-ionone, acetato de etila, cyclemax, Eugenol, d-Limoneno, Vivaldie, Ciclogalbanate, trans-Anetol, anetol, butirato de cis-3-Hexenila, acetato de Flor, Violiff, Aurantiol, Damascenone, trans-Pinoacetaldeído, DODECANAL, Eucaliptol, oxid de rosa, Undecanal (Aldeído de Undecil), Caproato de alila, Romascone, Heptanoato de alila, a-Irone, acetato de hexila, Liffarome, Vertoliff, aldeído anísico, gamma methyl ionone, NONANAL, Frutene, glicolato de amyl alila, Metil 2-octinoato, beta-Ionone, Etil Oenantato, Maltol, alfa-Damascone, Metil-2noninoato, gamma-Nonalactone, Dimetol, Metil Pamplemousse,metil ionone (Xandralia), 2-Nonen-1-al, Oxane, (E)-2,(Z)-6-Nonadienal, Trans-2-Hexenal, butirato de etila, acetato de fenila, Etil-2-metilbutirato, Melonal, acetato de Isoamila, 2,6-Nonadien-1-ol, (2E,6Z)-(Nonadienol), 10% Labienone Oxim (labienoxime) em DPG, caproato de Etila, Fenilacetaldeído, isobutil quinolina, manzanate, 2-Metilundecanal, Metil antranilato, cis-3,cis-6-nonadienol, Etil vanilina, BENZALDEÍDO, Neobutenone, triplal ou ligustral, 10-Undecenal, Citronellal, N-DECANAL, Vanilina, L-Carvone, Isociclocitral, OCTANAL, Petition 870210116931, of 16 / 12 / 2021, p. 97 / 122 17 / 36 Methyl benzoate, phenyl ethyl acetate, Citral, Indol, mixed mixtures. Stemone, Cashmeran, GERANIOL, Citronellol nitrile, Linalool, Ethyl linalool, Benzyl acetate, Undecavertol, Methyl phenyl carboxylic acid, 6-Nonen-1-ol, (6Z)-, Benzyl propionate, Iso-E Super, 2,6-Nonadien-1-ol, (2E,6Z)-(10% Nonadienol in DPG), cis-3-Hexen-1-ol (beta gamma hexenol), Isobomila acetate, Ambrox DL, Ozone propyl (Floralozona), 3-methyl-5-(2,2,3trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol (Ebanol), Phenyl isobutyrate, Florhydral, Phenyl ethyl alcohol, bourgeonal, gama-Undecalactone (racêmico), Diidromircenol, Etil 2-metil-1,3-dioxolane-2-acetato (Fructone), óxido de Bigarade, propionato de ciclohexil de Alila, Tetraidrolinalool (Tetraidro Linalool), Trimofix O, Citronellol, Neofolione, mistura de Hivernal, acetato de Linalila, Citroneliloxiacetaldeído, Delta-Muscenone, Romanolide, beta-Pineno, Karanal, Vertenex, acetato de o-terc-Butilciclohexila (verdox), Nectarila,gamaDecalactone, Isoeugenol, Heliotropin, Oxalone (Calone 1951), aldeído cinâmico, Diidro-beta-ionone, acetat de Etila, cyclemax, Eugenol, d-Limoneno, Vivaldie, Ciclogalbanate, trans-Anetol, anetol, butirato de cis-3-hexenila, acetat de Flor, Violiff, Aurantiol, Damascenone, trans-Pinoacetaldeído, DODECANAL, Eucaliptol, oxid de rosa, Undecanal (Aldeído de Undecila), Caproato de alila, Romascone, Heptanoato de alila, a-Irone, acetat de heptila, Liffarome, Vertoliff, aldeído anísico, gamma methyl ionone, NONANAL, Frutene, glicolato de amil alila, 2-octinoato Metila, beta-Ionone, Oenantato de Etila, Maltol, alfa-Damascone, Metil-2-noninoato, gamma-Nonalactone, Dimetol, Metil Pamplemousse, metil ionona (Xandralia), 2-Nonen-1-al, Oxane, (E)-2,(Z)-6-Nonadienal, Trans-2Hexenal, butirato de etila, Acetato de prenila, Etil-2-metilbutirato, Melonal, Acetato de isoamila, 2,6-Nonadien-1-ol, (2E,6Z)-(Nonadienol), 10% Labienone Oxim (labienoxime) em DPG, Caproato de etila, Fenilacetaldeído,isobutyl quinoline, manzanate, 2-Methylundecanal, Methyl Anthranilate, cis-3, cis-6nonadienol, Ethyl Vanillin, BENZALDEHYDE, Neobutenone, triplal or ligustral, 10-Undecenal, Citronellal, N-DECANAL, Vanillin, L-Carvone, Isocyclocitral, Petition 870210116931, dated 12 / 16 / 2021, pp. 98 / 122 18 / 36 Octanal, methyl benzoate, phenyl ethyl acetate, citral, indole, and mixtures thereof.
[0040] Additional suitable perfume raw materials include the following: Isoeugenol, Heliotropin, Oxalone (Calone 1951), Cinnamaldehyde, Dihydro-beta-ionone, Ethyl acetate, Cyclemax, Eugenol, d-Limonene, Vivaldie, Cyclogalbanate, trans-Anethole, Anethole, Hexenyl cis-3-Butyrate, Flower acetate, Violiff, Aurantiol, Damascenone, trans-Pinoacetaldehyde, Dodecanal, Eucalyptol, Rose oxide, Undecanal (Undecyl aldehyde), Allyl caproate, Romascone, Allyl heptanoate, α-Irone, Hexyl acetate, Liffarome, Vertoliff, Anisic aldehyde, Gamma methyl ionone, Nonanal, Frutene, Amyl glycolate allyl, Methyl 2-octinoate, beta-Ionone, Ethyl Oenanthate, Maltol, alpha-Damascone, Methyl-2-nonioate, gamma-Nonalactone, Dimetol, Methyl Pamplemousse, methyl ionone (Xandralia), Violiff, Aurantiol, Damascenone, trans-Pinoacetaldehyde, DODECANAL, Eucalyptol, Rose oxide, Undecanal (Undecyl Aldehyde), Allyl Caproate, Romascone, Allyl Heptanoate, a-Irone, Hexyl Acetate, Liffarome, Vertoliff,aldeído anísico, gama metil ionone, NONANAL, Frutene, glicolato de amil alila, Metil 2-octinoato, betaIonone, Etil Oenanthate, Maltol, alfa-Damascone, Metil-2-nonioato, gamaNonalactone, Dimetol, Metil Pamplemousse, metil ionone (Xandralia), 2-Nonen1-al, Oxane, (E)-2,(Z)-6-Nonadienal, Trans-2-Hexenal, butirato de etila, Acetato de prenila, Etil-2-metilbutirato, Melonal, Acetato de isoamila, 2,6-Nonadien-1-ol, (2E,6Z)-(Nonadienol), 10% Labienone Oxim (labienoxime) in DPG, Caproato de etila, Fenilacetaldeído, quinolina de isobutila, manzanate, 2-Methylundecanal, Antranilato de metila, cis-3, cis-6-nonadienol, Vanilina de etila, benzoaldeído, Neobutenone, triplal ou ligustral, 10-Undecenal, Citronellal, N-DECANAL, Vanilina, L-Carvone, Isociclocitral, OCTANAL, Benzoato de metila, acetato de phenyl ethyl, citral, indol, and mixtures of the same.,
[0041] Additional suitable perfume raw materials include the following: violiff, aurantiol, damascenone, trans-pinoacetaldehyde, dodecanal, eucalyptol, rose oxide, undecanal (aldehyde). Petition 870210116931, dated 12 / 16 / 2021, pp. 99 / 122 19 / 36 de undecila), Caproato de alila, Romascone, Heptanoato de alila, a-Irone, Acetato de hexila, Liffarome, Vertoliff, aldeído anísico, gama metil ionone, NONANAL, Frutene, glicolato de amil alila, Metil 2-octinoato, beta-Ionone, oenantato de Etila, Maltol, alfa-Damascone, Metil-2-nonioato, gamaNonalactone, Dimetol, Metil Pamplemousse, metil ionone (Xandralia), 2-Nonen1-al, Oxane, (E)-2,(Z)-6-Nonadienal, Trans-2-Hexenal, butirato de etila, Acetato de prenila, Etil-2-metilbutirato, Melonal, Acetato de isoamila, 2,6-Nonadien-1-ol, (2E,6Z)-(Nonadienol), 10% Labienone Oxim (labienoxima) em DPG, Caproato de etila, Fenilacetaldeído, quinolina de isobutila, manzanate, 2-Methylundecanal, Antranilato de metila, cis-3, cis-6-nonadienol, Vanilina de etila, benzoaldeído, Neobutenona, triplal ou ligustral, 10-Undecenal, Citronellal, N-DECANAL, Vanilina, L-Carvone, Isociclocitral, OCTANAL, Benzoate of methyl, Acetate of phenyl ethyl, Citral, Indole, and mixtures of the same.
[0042] Additionally, suitable perfume raw materials include the following: 2-Nonen-1-al, Oxane, (E)-2,(Z)-6-Nonadienal, Trans-2-Hexenal, Ethyl butyrate, Prenyl acetate, Ethyl-2-methylbutyrate, Melonal, Isoamyl acetate, 2,6-Nonadien-1-ol, (2E,6Z)-(Nonadienol), 10% Labienone Oxim (labienoxime) in DPG, Ethyl caproate, Phenylacetaldehyde, Isobutyl quinoline, Manzanate, 2-Methylundecanal, Methyl anthranilate, Cis-3,cis-6-nonadienol, Ethyl vanillin, BENZALDEHYDE, Neobutenone, Triplal or Ligustral, 10-Undecenal, Citronellal, N-DECANAL, Vanillin, L-Carvone, Isocyclocitral, Octanal, Methyl benzoate, Phenyl ethyl acetate, Citral, Indole, and mixtures thereof.
[0043] According to various embodiments, the disclosed fragrance compositions may additionally include one or more additional ingredients or excipients conventionally used in combination with fragrances in perfume compositions, for example, carrier materials, and other auxiliary agents commonly used in the art, for example, solvents, preservatives, antifungals, emulsifiers, stabilizers and the like. In various embodiments, the fragrance composition Petition 870210116931, dated 12 / 16 / 2021, pages 100 / 122 20 / 36 may include one or more solvents, such as, for example, alcohol, hydroalcohol, water, propylene glycol, dipropylene glycol (DPG), isopropyl myristate (IPM), and triethyl citrate (TEC), or combinations thereof.
[0044] According to some embodiments, a method of preparing the disclosed fragrance compositions includes combining one or more fragrance compounds with a glycoside. Advantageously, steviol glycosides can be added to fragrance compounds under ambient conditions. In the examples, the compositions of the present disclosure were added at ambient temperature and atmospheric pressure.
[0045] According to some embodiments, a glycoside may be added to a product or article including one or more fragrance compounds.
[0046] According to some embodiments, the fragrance compositions disclosed in the present invention can be used in a wide range of non-food and / or non-beverage articles and applications. For example, the fragrance compositions can be used in fragrance products and applications comprising an odorant, for example, in any field of functional and fine perfumery, such as perfumes, household products, laundry products, body care products and cosmetics.Specific illustrative, not limiting, examples include fine fragrances (e.g., eau de parfum and eau de toilette); household products (e.g., dishwashing detergents, surface cleaners, air fresheners, automotive care products, cleaning and / or treatment agents for hard surfaces (including toilet and floor cleaners) and other cleaning products for institutional or consumer use, cleaning detergents, in particulate or powder form; multi-purpose detergents in liquid, gel or paste form; liquid detergents for delicate fabrics; hand dishwashing detergents; dishwasher detergents, including various types of tablets, granules, liquid and rinsing aids for institutional and home use; cleaning and disinfecting agents, liquids, including. Petition 870210116931, dated 12 / 16 / 2021, pages 101 / 122 21 / 36 types of antibacterial hand washes, cleaning bars, car or carpet cleaners, bathroom cleaning agents including toilet bowl cleaners; and metal cleaning agents, fabric conditioning products including fabric softeners and / or purifiers, which may be in liquid, solid and / or desiccant tablet form; and cleaning adjuvants such as bleaching and “stain remover stick” or pre-treatment additives, substrate-laden products such as dryer sheets, wet and dry pads and wipes, non-woven substrates and sponges; as well as sprays and mists; products and / or processes relating to toilet paper, facial tissues, paper towels and handkerchiefs; tampons, feminine hygiene products; laundry products (e.g., fabric softener, bleach, detergent, odor / stain treatment);Personal care products for use by humans or domestic animals (e.g., aftershave lotion, soap, shampoo, conditioner, shower gel, bath and shower salts, hair products, body lotion, sunscreen, hygiene products); and cosmetics (e.g., deodorants, antiperspirants, beauty creams, makeup products).
[0047] According to the various modalities, the article comprises an effective quantity of the fragrance composition to provide a desired fragrance.
[0048] One embodiment of the present disclosure provides a perfume comprising water; a solvent, a glycoside, and a fragrance compound. The fragrance compound may be an oil, wherein the oil is at a concentration of about 1 to 20% by weight. The oil may be a perfume oil or an essential oil. In some embodiments, the solvent may be an alcohol. In some embodiments, the alcohol may be ethanol. The glycoside may be about 0.01 to 5.0% of the perfume by weight, about 0.1 to 1.0% of the perfume by weight, or about 0.1 to 0.5% of the perfume by weight.
[0049] One embodiment of the present disclosure provides a perfume consisting of water; one or more solvents, one or more glycosides and one or more fragrance compounds. The fragrance compound may be a Petition 870210116931, dated 12 / 16 / 2021, pages 102 / 122 22 / 36 oil, wherein the oil is in a concentration of about 1 to 20% by weight. The oil may be a perfume oil or an essential oil. In some embodiments, the solvent may be an alcohol. In some embodiments, the alcohol may be ethanol. The glycoside may be about 0.01 to 5.0% of the perfume by weight, about 0.1 to 1.0% of the perfume by weight, or about 0.1 to 0.5% of the perfume by weight.
[0050] One embodiment of the present disclosure provides a perfume consisting essentially of water; one or more solvents, one or more glycosides, and one or more fragrance compounds. The fragrance compound may be an oil, wherein the oil is at a concentration of about 1 to 20% by weight. The oil may be a perfume oil or an essential oil. In some embodiments, the solvent may be an alcohol. In some embodiments, the alcohol may be ethanol. The glycoside may be about 0.01 to 5.0% of the perfume by weight, about 0.1 to 1.0% of the perfume by weight, or about 0.1 to 0.5% of the perfume by weight. The phrase “consisting essentially of” as used in this aspect refers to the perfume including other components that do not materially affect the basic and novel characteristics of the perfume, such as those that might be found in residual amounts or other components that do not alter the fixative characteristics of the perfume, but may otherwise be found in a perfume.The phrase "consisting essentially of" as applied to perfumes is an unlimited term, allowing the presence of one or more components that could be found in a perfume other than those mentioned, provided that basic or new characteristics of what is mentioned are not altered by the presence of one or more of the components different from those mentioned, but excludes prior art modalities.
[0051] The embodiments of the present disclosure provide non-edible products comprising at least one fragrance compound, a glycoside and an anionic surfactant. Petition 870210116931, dated 12 / 16 / 2021, pages 103 / 122 23 / 36
[0052] The embodiments of the present disclosure provide non-edible products comprising sodium hypochlorite, at least one fragrance compound and a glycoside.
[0053] The embodiments of the present disclosure provide non-edible products comprising at least one fragrance compound, a glycoside, an enzyme protein and a surfactant.
[0054] The embodiments of the present disclosure provide non-edible detergents comprising at least one fragrance compound, a glycoside, an enzyme protein and a detergent surfactant. In some embodiments, the non-edible detergent may include a bleaching agent.
[0055] The embodiments of the present disclosure provide non-edible products comprising sodium carbonate, citric acid, at least one fragrance compound and a glycoside.
[0056] The embodiments of the present disclosure provide non-edible products comprising ammonia, at least one fragrance compound and a glycoside. EXAMPLES
[0057] Having now described the modalities of revelation in general, the examples describe some additional modalities. Although modalities of the present revelation are described in relation to the example and the corresponding text and figures, there is no intention to limit the modalities of revelation to these descriptions. On the contrary, the intention is to encompass all alternatives, modifications, and equivalents included in the spirit and scope of modalities of the present revelation.
[0058] Unless otherwise specified, all percentages mentioned in the examples are weight / weight. In the examples provided below, panel studies were conducted to evaluate the effectiveness of steviol glycosides as a fragrance fixative and to determine whether the addition of the glycosides negatively affected the preferences of Petition 870210116931, dated 12 / 16 / 2021, pages 104 / 122 24 / 36 participants were tested for fragrances. The intensity and duration of fragrance is not easily measured quantitatively, so instead it can be characterized based on human evaluations. To qualitatively assess the fragrance, panel studies were conducted as follows. In each panel, there were ten participants. For non-skin applications, a blotting paper (perfume test strip, or Mouillette) was dipped one-third of its length into the fragrance composition and left in the open air. Panel participants were asked to rate the fragrance over a 48-hour period, with observations recorded at 2 hours, 4 hours, 6 hours, 12 hours, 24 hours, and 48 hours. For skin applications, a single spray was applied from a distance of 6 inches onto the participant's wrist and allowed to dry for 20 seconds. Panel participants were asked to rate the fragrance, with observations recorded every 2 hours for 8 hours.Participants indicated a preference for one scent over another and rated the intensity of the scents as more intense, the same, or weaker. EXAMPLE 1 - PERFUME
[0059] In this example, an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside was prepared and compared with a control composition comprising the same fragrance compound but without the glycoside. Recipes for comparative composition 1-A and exemplary fragrance composition 1-B are provided in Table 1. TABLE 1 Petition 870210116931, dated 12 / 16 / 2021, pages 105 / 122 25 / 36 1-A 1-B Aldehyde - floral perfume oil 12.0% 12.0% Steviol Glycosides (Rebaudioside A 80%) 0.0% 0.5% Alcohol 88.0% 87.5% Total 100.0% 100.0%
[0060] In panel studies, over periods ranging from one to 48 hours, 90% of panelists observed longer lasting properties (e.g., approximately 36 hours) on the skin in the exemplary formulation with 0.5% Rebaudioside A 80% (1-B) compared to the formulation without steviol glycosides (1-A). In perfume blotter tests lasting 48 hours, 90% of panelists made the same observation. EXAMPLE 2 - POST-BATH SPLASH
[0061] In this example, a post-bath splash product was prepared having an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside and compared with a post-bath splash product having a control composition comprising the same fragrance compound but without the glycoside. The recipes for comparative splash-bath composition 2-A and exemplary splash-bath composition 2-B are provided in Table 2. TABLE 2 Petition 870210116931, dated 12 / 16 / 2021, pages 106 / 122 26 / 36 2-A 2-B Perfume Oil Fougere Citrus Lavender 12.0% 12% Steviol Glycosides (Rebaudioside A 97%) 0.0% 0.1% Alcohol 66.2% 66.1% Water 21.8% 21.8% Total 100% 100%
[0062] In panel studies, 90% of panelists observed longer-lasting skin properties in the exemplary formulation with 0.1% Rebaudioside A 97% (2-B) compared to the comparator formulation without steviol glycosides (2-A). Panelists observed that in the exemplary formulation (2-B), the fragrances lasted 48 hours longer. In perfume blotter tests, 100% of panelists made the same observation. EXAMPLE 3 - EAU DE TOILETTE
[0063] In this example, an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside was prepared and compared with a control composition comprising the same fragrance compound but without the glycoside. Recipes for comparative composition 3-A and exemplary fragrance composition 3-B are provided in Table 3. TABLE 3 Petition 870210116931, dated 12 / 16 / 2021, pages 107 / 122 27 / 36 3-A 3-B Woody herbal perfume oil 8.0% 8.0% Steviol Glycosides (Rebaudioside A 50%) 0.0% 0.1% Alcohol 86.0% 85.9% Water 6.0% 6.0% Total 100% 100%
[0064] In panel studies, 90% of panelists preferred the fragrance of the exemplary formulation with Rebaudioside A 50% (3-B) on the skin compared to that of the comparative composition 3-A. In perfume blotters, 100% of panelists preferred the fragrance of the exemplary formulation 3-B. EXAMPLE 4 - COLONY
[0065] In this example, an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside was prepared and compared with a control composition comprising the same fragrance compound but without the glycoside. Recipes for comparative composition 4-A and exemplary fragrance composition 4-B are provided in Table 4. TABLE 4 4-A 4-B Floral citrus perfume oil 5.0% 5.0% Steviol glycosides (GSG 80%) 0.0% 0.1% Alcohol 75.0% 74.9% Water 20.0% 20.0% Total 100% 100% Petition 870210116931, dated 12 / 16 / 2021, pages 108 / 122 28 / 36
[0066] In panel studies, 90% of panelists preferred the fragrance of the cologne including Steviol Glycosides (GSG 80%) (4-B) on the skin compared to the comparator cologne that excludes the glycoside. In the perfume blotters, 90% of panelists preferred the fragrance of the exemplary cologne product 4-B. EXAMPLE 5 - AFTERSHAVE LOTION
[0067] In this example, a shaving lotion was prepared having an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside and compared with a shaving lotion having a control composition comprising the same fragrance compound but without the glycoside. The recipes for comparative shaving lotion composition 5-A and exemplary shaving lotion fragrance composition 5-B are given in Table 5. TABLE 5 5-A 5-B Spanish leather perfume oil 0.6% 0.6% Steviol glycosides (GSG 90%) 0.0% 0.5% Alcohol 63.0% 62.5% Water 36.4% 36.4% Total 100% 100%
[0068] In panel studies over periods ranging from one to twenty-four hours, 90% of panelists determined longer-lasting properties on the skin for the product with Steviol Glycosides (GSG 90%) (5-B) compared to the product without these steviol glycosides (5-A). In perfume blotters, 80% of panelists preferred the lasting quality of product (5-B). EXAMPLE 6 - HAND CREAM Petition 870210116931, dated 12 / 16 / 2021, pages 109 / 122 29 / 36
[0069] In this example, a hand cream was prepared having an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside and compared with a hand cream having a control composition comprising the same fragrance compound but without the glycoside. The recipes for the comparative hand cream composition 6-A and exemplary hand cream composition 6-B are given in Table 6. TABLE 6 6-A 6-B Floral perfume oil 0.6% 0.6% Steviol glycosides (GSG 90%) 0.0% 0.2% Albagel 1.5% 1.5% Stearic acid 2.0% 2.0% Mineral oil 6% 6% Cetyl alcohol 2.0% 2.0% Acetylated lanolin 2% 2% Methyl glucoside sesquitearate 0.8% 0.8% Glycerin 5% 5% Water 86.1% 85.9% Total 100% 100%
[0070] During a period of one to four hours, the hand cream with Steviol Glycosides (GSG 90%) (6-B) was judged by 80% of the panelists as exhibiting a fragrance having greater intensity and longer lasting potency than the fragrance of the comparator hand cream without steviol glycoside (6-A). EXAMPLE 7 - SOAP BARS Petition 870210116931, dated 12 / 16 / 2021, pages 110 / 122 30 / 36
[0071] In this example, a bar of soap was prepared having an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside and compared with a bar of soap having a control composition comprising the same fragrance compound but without the glycoside. The recipes for control bar soap composition 7-A and exemplary bar soap composition 7-B are given in Table 7. TABLE 7 1-A 1-B Lilac perfume oil 1.5% 1.5% Steviol glycosides (GSG 90%) 0.0% 0.3% Soap material 98.5% 98.2% Total 100% 100.0%
[0072] In handwashing use tests, 90% of panelists judged the fragrance intensity in soap bars containing Steviol Glycosides (GSG 90%) (7-B) to be greater than that in bars without Steviol Glycosides (GSG 90%). In the handwashing use test, half of the panelists were instructed to wash their hands using their normal handwashing procedure with soap bars containing steviol glycosides while the other half of the panelists used soap bars without steviol glycosides. EXAMPLE 8 - REDUCTION OF CONCENTRATION OF Perfume Oil in Perfume
[0073] In this example, an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside was prepared and compared with a control composition comprising the same fragrance compound, Petition 870210116931, dated 12 / 16 / 2021, pages 111 / 122 31 / 36 but without glycoside. Recipes for comparative composition 8-A and exemplary fragrance composition 8-B are provided in Table 8. TABLE 8 8-A 8-B Aldehyde - floral perfume oil 12.0% 10.0% Steviol Glycosides (Reb A 80%) 0.0% 0.5% Alcohol 88.0% 89.5% Total 100% 100.0%
[0074] In panel tests on skin and perfume blotters, 40% of panelists judged the exemplary Formula 8-B as having a more intense fragrance than the comparative Formula 8-A. The remaining 60% judged that 8-A and 8-B have equivalent fragrance. This indicates that by using the glycoside in the fragrance composition, it may be possible to reduce the amount of fragrance compound without diminishing the perceived fragrance of the fragrance composition. The use of such a reduced concentration of perfume oils without adverse effect on odor perception will provide significant savings in material costs. EXAMPLE 9 - REDUCING THE CONCENTRATION OF PERFUME OIL IN COLOGNES
[0075] In this example, an exemplary fragrance composition comprising a fragrance compound and a steviol-based glycoside was prepared and compared with a control composition comprising the same fragrance compound but without the glycoside. Recipes for comparative composition 9-A and exemplary fragrance composition 9-B are provided in Table 9. TABLE 9 Petition 870210116931, dated 12 / 16 / 2021, pages 112 / 122 32 / 36 9-A 9-B Floral-citrus perfume oil 5.0% 4.0% Steviol glycosides (Reb A 80%) 0.0% 0.1% Alcohol 95.0% 95.9% Total 100% 100.0%
[0076] In panel tests, 40% of panelists judged Formula 9-B with Steviol Glycosides (Reb A 80%) as having a stronger fragrance than Formula 9-A without Steviol Glycosides (Reb A 80%); 30% found no difference between the two fragrances, and 30% judged that 9-A has a more intense fragrance. Thus, 70% of panelists judged Formula 9-B with Steviol Glycosides (Reb A 80%) as having a more intense fragrance than Formula 9-A without Steviol Glycosides (Reb A 80%); 30% found no difference between the two fragrances; and 30% judged that 9-A has a more intense fragrance. This indicates that by using the glycoside, it may be possible to reduce the amount of fragrance compound without diminishing the perceived fragrance, but with greater inherent cost savings. The tests were performed on skin and blotters.
[0077] The present disclosure will be better understood after reading the following numbered aspects, which should not be confused with the claims. Any of the numbered aspects below may, in some cases, be combined with aspects described elsewhere in this disclosure, and such combinations are intended to form part of the disclosure.
[0078] Aspect 1. A fragrance composition comprising at least one fragrance compound, and a glycoside selected from a steviol glycoside, a glycosylated steviol glycoside, a derivative of a steviol glycoside, a derivative of a glycosylated steviol glycoside or combinations thereof. Petition 870210116931, dated 12 / 16 / 2021, pages 113 / 122 33 / 36
[0079] Aspect 2. The fragrance composition of claim 1, further comprising / consisting of a solvent, wherein the solvent is selected from alcohol, hydro alcohol, water, propylene glycol or a combination thereof.
[0080] Aspect 3. The fragrance composition of any of the preceding aspects, wherein the glycoside comprises / consists of about 0.001 to 0.5% by weight based on the total weight of the fragrance composition.
[0081] Aspect 4. Fragrance composition, according to any of the preceding aspects, wherein the glycoside is a steviol glycoside selected from Rebaudioside A, Rebaudioside B, Rebaudioside C, Rebaudioside D, Rebaudioside E, Rebaudioside F, Rebaudioside M, Rebaudioside N, Rebaudioside O.
[0082] Aspect 5. Fragrance composition according to any of the preceding aspects, wherein the steviol glycoside is enzymatically treated stevia extract.
[0083] Aspect 6. Fragrance composition according to any of the preceding aspects, wherein the glycosylated steviol glycoside has a low degree of glycosylation, wherein the number of glucose molecules attached to the steviol glycoside is from one to five.
[0084] Aspect 7. Fragrance composition according to any of the preceding aspects, wherein the glycosylated steviol glycoside has a high degree of glycosylation where the number of glucose molecules linked to the steviol glycoside is from six to ten.
[0085] Aspect 8. Product including a fragrance composition, the fragrance composition comprising / consisting of at least one fragrance compound and a glycoside selected from steviol glycoside, a glycosylated steviol glycoside, a steviol glycoside derivative, a glycosylated steviol glycoside derivative, or combinations thereof. Petition 870210116931, dated 12 / 16 / 2021, pages 114 / 122 34 / 36
[0086] Aspect 9. Product according to any of the preceding aspects, wherein the product is selected from a perfume, an eau de toilette, a lotion, a soap, a cosmetic, a body care product.
[0087] Aspect 10. Product, according to any of the preceding aspects, wherein the product is selected from a dishwashing detergent, a surface cleaning agent, an air freshener, a fabric softener, a bleach or a laundry detergent.
[0088] Aspect 11. Product, according to any of the preceding aspects, further comprising / consisting of a solvent, wherein the solvent is selected from alcohol, hydroalcohol, water, propylene glycol or a combination thereof.
[0089] Aspect 12. Product, according to any of the preceding aspects, wherein the glycoside comprises / consists of about 0.001 to 0.5% by weight based on the total weight of the fragrance composition.
[0090] Aspect 13. Product, according to any of the preceding aspects, wherein the glycoside is a steviol glycoside selected from Rebaudioside A, Rebaudioside B, Rebaudioside C, Rebaudioside D, Rebaudioside E, Rebaudioside F, Rebaudioside M, Rebaudioside N, Rebaudioside O.
[0091] Aspect 14. Product, according to any of the preceding aspects, in which the steviol glycoside is enzymatically treated stevia extract.
[0092] Aspect 15. Product, according to any of the preceding aspects, wherein the glycosylated Stevia glycoside has a low degree of glycosylation, wherein the number of glucose molecules linked to the steviol glycoside is from one to five.
[0093] Aspect 16. Product, according to any of the preceding aspects, in which the glycosylated steviol glycoside has a high Petition 870210116931, dated 12 / 16 / 2021, pages 115 / 122 35 / 36 degree of glycosylation where the number of glucose molecules linked to the steviol glycoside is six to ten.
[0094] Aspect 17. Non-cosmetic product comprising a perfume, the perfume comprising / consisting of water, a solvent, a glycoside and a fragrance compound.
[0095] Aspect 18. Non-edible product according to claim 17, wherein the glycoside is selected from a steviol glycoside, a glycosylated steviol glycoside, a derivative of a steviol glycoside, a derivative of a glycosylated steviol glycoside, or combinations thereof.
[0096] Aspect 19. Non-edible product, according to any of the preceding aspects, wherein the solvent is selected from alcohol, hydroalcohol, water, propylene glycol or a combination thereof.
[0097] Aspect 20. Non-edible product according to any of the preceding aspects, wherein the glycoside comprises / consists of about 0.001 to 0.5% by weight based on the total weight of the fragrance composition.
[0098] It should be noted that ratios, concentrations, quantities, and other numerical data may be expressed in the present invention in a range format. It should be understood that such a range format is used for convenience and brevity, and thus should be interpreted in a flexible manner to include not only the numerical values explicitly cited as the limits of the range, but also to include all individual numerical values or subranges encompassed within that range as if each numerical value and subrange were explicitly cited. To illustrate, a concentration range of “about 0.1% to about 5%” should be interpreted as including not only the explicitly cited concentration of about 0.1% by weight to about 5% by weight, but also individual concentrations (e.g., 1%, 2%, 3%, and 4%) and subranges (e.g., 0.5%, 1.1%, Petition 870210116931, dated 12 / 16 / 2021, pp. 116 / 122 36 / 36 2.2%, 3.3%, and 4.4% are within the indicated range. In one embodiment, “about 0” may refer to 0, 0.001, 0.01, or 0.1. In one embodiment, the term “about” may include traditional rounding according to significant figures of the numerical value. Furthermore, the phrase “about 'x' to 'y'” includes “about 'x' to about 'y'”.
[0099] It should be emphasized that the embodiments described above of the present disclosure are merely examples of possible implementations, and are set forth only for a clear understanding of the principles of the disclosure. Many variations and modifications may be made to the embodiments described above of the disclosure without departing substantially from the spirit and principles of the disclosure. All such modifications and variations are intended to be included in the present invention without the scope of this disclosure.
Claims
CLAIMS 1. Fragrance composition for a non-edible product, characterized in that it comprises: at least one fragrance compound; and a glycoside selected from a steviol glycoside, a glycosylated steviol glycoside, a derivative of a steviol glycoside, a derivative of a glycosylated steviol glycoside, or combinations thereof, wherein the glycoside is a fragrance fixative such that, by the inclusion of the glycoside: the perceived duration of the fragrance is increased by the addition of the glycoside, or the perceived intensity of the fragrance compound does not decrease when reduced by about 1% to 2%.
2. Fragrance composition, according to claim 1, characterized in that it further comprises a solvent, wherein the solvent is selected from alcohol, hydroalcohol, water, propylene glycol or a combination thereof.
3. Fragrance composition, according to claim 1, characterized in that the glycoside comprises about 0.001 to 0.5% by weight based on the total weight of the fragrance composition.
4. Fragrance composition according to claim 1, characterized in that the glycoside is a steviol glycoside selected from Rebaudioside A, Rebaudioside B, Rebaudioside C, Rebaudioside D, Rebaudioside E, Rebaudioside F, Rebaudioside M, Rebaudioside N, Rebaudioside O.
5. Fragrance composition, according to claim 1, characterized in that the steviol glycoside is an enzymatically treated stevia extract. Petition 870250068093, dated 04 / 08 / 2025, page 17 / 24 2 / 4 6. Fragrance composition, according to claim 1, characterized in that the glycosylated steviol glycoside has a low degree of glycosylation, where the number of glucose molecules linked to the steviol glycoside is from one to five.
7. Fragrance composition, according to claim 1, characterized in that the glycosylated steviol glycoside has a high degree of glycosylation where the number of glucose molecules linked to the steviol glycoside is from six to ten.
8. Non-edible product including a fragrance composition as defined in claims 1 to 7, characterized in that the fragrance composition comprises at least one fragrance compound; and a glycoside selected from a steviol glycoside, a glycosylated steviol glycoside, a derivative of a steviol glycoside, a glycosylated steviol glycoside derivative, or combinations thereof; wherein the glycoside is a fragrance fixative such that, by the inclusion of the glycoside: the perceived duration of the fragrance is increased by the addition of the glycoside, or the perceived intensity of the fragrance compound does not decrease when reduced by about 1% to 2%.
9. Product according to claim 8, characterized in that the product is selected from a perfume, a cologne, a lotion, a soap, a cosmetic or a body care product.
10. Product according to claim 8, characterized in that the product is selected from a dishwashing detergent, a surface cleaning agent, an air freshener, a fabric softener, a bleach, or a laundry detergent.
11. Product according to claim 8, characterized in that it further comprises a solvent, Petition 870250068093, dated 04 / 08 / 2025, page 18 / 24 3 / 4, wherein the solvent is selected from alcohol, hydroalcohol, water, propylene glycol or a combination thereof.
12. Product according to claim 8, characterized in that the glycoside comprises from about 0.001 to 0.5% by weight based on the total weight of the fragrance composition.
13. Product according to claim 8, characterized in that the glycoside is a steviol glycoside selected from Rebaudioside A, Rebaudioside B, Rebaudioside C, Rebaudioside D, Rebaudioside E, Rebaudioside F, Rebaudioside M, Rebaudioside N, Rebaudioside O.
14. Product according to claim 8, characterized in that the steviol glycoside is an enzymatically treated stevia extract.
15. Product according to claim 8, characterized in that the glycosylated steviol glycoside has a low degree of glycosylation, where the number of glucose molecules linked to the steviol glycoside is from one to five.
16. Product according to claim 8, characterized in that the glycosylated steviol glycoside has a high degree of glycosylation where the number of glucose molecules linked to the steviol glycoside is from six to ten.
17. Non-edible product, characterized in that it comprises a perfume, the perfume comprising water, ethanol, a glycoside and a fragrance compound, wherein the glycoside is a fragrance fixative.
18. Non-edible product, according to claim 17, characterized in that the glycoside is selected from a steviol glycoside, a glycosylated steviol glycoside, a derivative of a steviol glycoside, a derivative of a glycosylated steviol glycoside, or combinations thereof. Petition 870250068093, dated 04 / 08 / 2025, page 19 / 24 4 / 4 19. Non-edible product, according to claim 17, characterized in that it further comprises alcohol, hydroalcohol, water, propylene glycol or a combination thereof.
20. Non-cosmetic product according to claim 17, characterized in that the glycoside comprises from about 0.001 to 0.5% by weight based on the total weight of the fragrance composition.