Method of control of pathogens in soybeans

Description

1 / 47 PATHOGEN CONTROL METHOD IN SOYBEANS

[0001] The present invention relates to a method of controlling pathogens in soybean crops. In particular, it relates to the use of a compound of formula (I), or a composition comprising a compound of formula (I), to control pod anomaly in soybeans and to a method of using said compound or composition.

[0002] WO 2007 / 048556 discloses that certain heterocyclic amide derivatives have microbicidal activity, as well as fungicidal activity. In particular, a compound of formula (I), (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methane-naphthalen-5-yl)-amide of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid is disclosed: (I)

[0003] The compound of formula (I) refers to benzovindiflupir as the active ingredient, with the following CAS number: 1072957-71-1.

[0004] In recent years, particularly since the 2019 / 2020 harvest, new adverse effects have been reported in soybean pods in Brazil. These manifest as pod and / or seed abortion at the grain-filling stage (typically from stage R5 of the soybean growth stages). In some cases, the pods are aborted from the plant; in others, the pods remain attached to the plants, but the grain is unable to complete its development. As reported in the magazine “Cultivate Great Crops” (Cultivar Grandes Culturas, October 2022, edition Petition 870260070412, dated 07 / 15 / 2026, page 11 / 105 2 / 47 (281 pp26-28, ISSN 1716-358x) and reported by Embrapa Soja in 2022, the problem occurred from the R5.4 development stage (51% to 75% grain formation) causing a 20% reduction in soybean productivity and a 30% reduction in grain quality. Symptoms appeared as rot at the pod junction, evolving into partial or total pod necrosis, causing pod rot, splitting, and sometimes pod abortion. The seeds in the pods were also compromised and appeared wrinkled and differed in color compared to normal (healthy) seeds (e.g., compromised seeds appear darker or paler than typically healthy seeds).

[0005] Given that pod anomaly represents a new soybean disease, very little is known about its cause, and information is based primarily on symptomatology. It has been postulated that the cause may be abiotic (e.g., environmental), biotic (some form of phytopathogen), or even a confluence of both. It has been proposed that anthracnose (a disease caused by the fungus Colleotricum truncatum) may have been linked to pod anomaly; however, this is not the whole story, as infection with this opportunistic pathogen does not result in green pods falling off soybean plants.

[0006] The present invention arises from the observation that several different phytopathogenic fungi are present in the tissue of soybean plants affected by pod anomaly, as shown here in the Examples. The combination of these specific fungi is unexpected. It has now been surprisingly discovered that the compound of formula (I), or a composition comprising a compound of formula (I), is highly effective in combating, preventing or controlling pod anomaly in soybeans and is, surprisingly, more effective against this specific combination than other SDHI fungicides. Petition 870260070412, dated 07 / 15 / 2026, page 12 / 105 3 / 47

[0007] Accordingly, the present invention provides the use of a compound of formula (I), (I) or a composition comprising a compound of formula (I), to control pod anomaly in soybeans.

[0008] In a second aspect of the invention, the use of a compound of formula (I) is provided. (I) or a composition comprising a compound of formula (I), to control post-harvest seed degradation in soybeans.

[0009] In a third aspect, a method is provided for combating, preventing or controlling pod anomaly in soybeans, comprising applying to the soybean crop, its locus or its propagation material, a compound of formula (I) or a composition comprising a compound of formula (I). Petition 870260070412, dated 07 / 15 / 2026, page 13 / 105 4 / 47

[0010] In a fourth aspect, a method is provided for combating, preventing or controlling post-harvest seed degradation in soybeans, comprising applying to the soybean crop, its locus or its propagation material, a compound of formula (I) or a composition comprising a compound of formula (I).

[0011] As used herein, the term combat, prevent or control, and its inflections, in the context of the present invention, means reducing any undesirable effect, such as pathogenic and, more particularly, phytopathogenic, especially fungi, such as (but not limited to) Cercospora spp., Colletotrichum spp., Corynespora spp. or Diaporthe spp., infestation or attack of, and pathogenic damage to a plant or a plant-derived product to such a level that an improvement is demonstrated.

[0012] As used herein, the term “pod anomaly” refers to a phenotypic pathology of soybean pods, in which the pod exhibits at least partial necrosis and / or seeds from affected pods develop abnormally. Pod anomaly has also been associated with stem breakage / stem rust, in which black or brown streaks are observed externally on stems and the inner pith of stems exhibits necrosis. When these symptoms also occur, the disease pathology is referred to herein as soybean anomaly.

[0013] The compound of formula (I) can occur in two different stereoisomers, which are described as the unique enantiomers of formulas (I)ie (I)ii: Petition 870260070412, dated 07 / 15 / 2026, p. 14 / 105 5 / 47 (I)i (I)|I

[0014] The present invention encompasses all such stereoisomers and their mixtures in any ratio. According to the invention, “racemic compound of formula (I)” means a racemic mixture of compounds of formula (I)| and (I)i i.

[0015] The compound of formula (I) can be prepared as described in WO 2007 / 048556.

[0016] The compound of formula (I) can be applied in an effective amount in fungicidal terms. As used herein, the term “effective amount” refers to the amount of the compound which, after single or multiple applications, provides the desired effect. An effective amount is readily determined by a person skilled in the art, using known techniques and by observing the results obtained under analogous circumstances. In determining the effective amount, several factors are considered, including, but not limited to: the type of plant or derived product to which it is applied; the pest to be controlled and its life cycle; the specific compound applied; the type of application; and other relevant circumstances.

[0017] The compounds of the invention are suitable for use in any soybean plant, including those that have been genetically modified to be resistant to active ingredients, such as Petition 870260070412, dated 07 / 15 / 2026, page 15 / 105 6 / 47 herbicides, or to produce active compounds that control plant pest infestations.

[0018] In a further preferred embodiment, transgenic plants and plant cultivars obtained by methods of genetic manipulation, if appropriate, in combination with conventional methods (Genetically Modified Organisms), and their parts are treated. Particularly preferred, plants of the plant cultivars, which are, in each case, commercially available or in use, are treated according to the invention. Plant cultivars are understood to mean plants having new properties (“traits”) that have been obtained by conventional breeding, by mutagenesis or by recombinant DNA techniques. These may be cultivars, bio- or genotypes.

[0019] Preferred transgenic plants or plant cultivars (obtained by genetic manipulation), which are to be treated according to the invention, include all plants that, by virtue of genetic modification, have received genetic material that confers particularly advantageous traits useful to these plants. Examples of such traits are improved plant growth, increased tolerance to high or low temperatures, increased tolerance to drought or water or salt content in the soil, increased flowering performance, easier harvesting, accelerated maturation, higher crop yields, higher quality and / or higher nutritional value of harvested products, improved storage stability and / or processability of harvested products. Preferably, the transgenic plants or plant cultivars are selected from Bt soybean plants.

[0020] Additional and particularly emphasized examples of such traits are improved plant defense against animal and microbial pests, such as insects, mites, and phytopathogenic fungi, Petition 870260070412, dated 07 / 15 / 2026, page 16 / 105 7 / 47 bacteria and / or viruses, and also increased tolerance of plants to certain active compounds in terms of herbicides.

[0021] Traits that are particularly emphasized are the increased plant defense against insects, arachnids, nematodes, and slugs and snails by virtue of toxins formed in the plants, in particular those formed in the plants by the genetic material of Bacillus thuringiensis (e.g., by the genes CrylA(a), CrylA(b), CrylA(c), CryllA, CrylllA, CryIIIB2, Cry9c, Cry2Ab, Cry3Bb and CrylF and also their combinations) (referred to here as “Bt plants”). Traits that are also particularly emphasized are the increased plant defense against fungi, bacteria and viruses by systemic acquired resistance (SAR), systemin, phytoalexins, elicitors and resistance genes and correspondingly expressed proteins and toxins.

[0022] Traits that are further emphasized are the increased tolerance of plants to certain active compounds in terms of herbicides, for example imidazolinones, sulfonylureas, glyphosate or phosphinothricin (e.g., the PAT gene). The genes that confer the desired traits in question may be present in combination with one another in transgenic plants.

[0023] Examples of “Bt plants” are soybean varieties that are sold under the registered names YIELD GARD® or INTACTA®.

[0024] Examples of herbicide-tolerant plants that can be mentioned are soybean varieties that are sold under the registered names Roundup Ready® (glyphosate tolerance), Liberty Link® (phosphinothricin tolerance), IMI® (imidazolinone tolerance) and STS® (sulfonylurea tolerance).

[0025] Herbicide-resistant plants (plants conventionally improved for herbicide tolerance) that may be mentioned include varieties sold under the registered name Clearfield® (e.g., maize). Petition 870260070412, dated 07 / 15 / 2026, page 17 / 105 8 / 47

[0026] Of particular interest are soybean plants carrying traits conferring resistance to 2,4-D (e.g., Enlist®), glyphosate (e.g., Roundup Ready®, Roundup Ready 2 Yield®), sulfonylurea (e.g., STS®), glufosinate (e.g., Liberty Link®, Ignite®), Dicamba (Monsanto), and tolerance to HPPD (e.g., isoxaflutol herbicide) (Bayer CropScience, Syngenta). Double or triple stacks in soybean plants of any of the traits described here are also of interest, including tolerance to glyphosate and sulfonylurea (e.g., Optimum GAT®, plants stacked with STS® and Roundup Ready® or Roundup Ready 2 Yield®), and tolerance to dicamba and glyphosate (Monsanto). Soybeans resistant to Soybean Cyst Nematode (SCN® - Syngenta) and soybeans with aphid resistance trait (AMT®) are also of interest.

[0027] These statements also apply to plant cultivars having these genetic traits or genetic traits yet to be developed, and these plant cultivars will be developed and / or marketed in the future.

[0028] Genetically modified crops can be described at the following site https: / / www.isaaa.org / gmapprovaldatabase, incorporated by reference therein, and more particularly can be selected from the data in Table 1 below: Table 1 Name and Event Code Registered Name Soybean - Glycine max L.: 40 Events Name: 260-05 (G94-1, G94-19, G168) Code: DD-026005-3 not available Name: A2704-12 Code: ACS-GM005-3 Liberty® Link Soybean Name: A2704-21 Liberty® Link Soybean Petition 870260070412, dated 07 / 15 / 2026, page 18 / 105 9 / 47 Name and Event Code Registered Name Code: ACS-GM004-2 Name: A5547-127 Code: ACS-GM006-4 Liberty® Link Soybeans Name: A5547-35 Code: ACS-GM008-6 Liberty® Link Soybeans Name: CV127 Code: BPS-CV127-9 Cultivance Name: DAS44406-6 Code: DAS-44406-6 not available Name: DAS68416-4 Code: DAS-68416-4 not available Name: DAS68416-4 x MON89788 Code: DAS-68416-4 x MON-89788-1 not available Name: DAS81419 Code: DAS-81419-2 not available Name: DAS81419 x DAS44406 Code: DAS-81419-2 x DAS-44406-6 Conkesta Soybean E3™ Name: DBN9004 Code: DBN-09004-6 not available Name: DP305423 Code: DP-305423-1 Treus™, Plenish™ Name: DP305423 x GTS 40-3-2 not available Petition 870260070412, dated 07 / 15 / 2026, p. 19 / 105 10 / 47 Name and Event Code Registered Name Code: DP-305423-1 x MON-04032-6 Name: DP305423 x MON87708 x MON89788 Code: DP-305423-1 x MON-87708-9 x MON-89788-1 not available Name: DP356043 Code: DP-356043-5 Optimum GAT™ Name: FG72 (FG072-2, FG072-3) Code: MST-FG072-2 not available Name: FG72 x A5547-127 Code: MST-FG072-2 x ACS-GM006-4 Liberty Link® GT27™ Name: GMB151 Code: BCS-GM151-6 not available Name: GTS 40-3-2 (40-3-2) Code: MON-04032-6 Roundup Ready™ Soybeans Name: GU262 Code: ACS-GM003-1 Liberty Link™ Soybeans Name: HB4 Code: IND-00410-5 Verdeca HB4 Soybeans Name: HB4 x GTS 40-3-2 Code: IND-00410-5 x MON-04032-6 not available Name: MON87701 Code: MON-87701-2 not available Petition 870260070412, dated 07 / 15 / 2026, p. 20 / 105 11 / 47 Name and Event Code Registered Name Name: MON87701 x MON89788 Code: MON-87701-2 x MON-89788-1 Intacta™ Roundup Ready™ 2 Pro Name: MON87705 Code: MON-87705-6 Vistive Gold™ Name: MON87705 x MON87708 x MON89788 Code: MON-87705-6 x MON-87708-9 x MON-89788-1 n / a Name: MON87705 x MON89788 Code: MON-87705-6 x MON-89788-1 not available Name: MON87708 Code: MON-87708-9 Genuity® Roundup Ready™ 2 Xtend™ Name: MON87708 x MON89788 Code: MON-87708-9 x MON-89788-1 not available Name: MON87708 x MON89788 x A5547127 Code: MON-87708-9 x MON-89788-1 x ACS-GM006-4 not available Name: MON87712 Code: MON-87712-4 Not available Name: MON87751 Code: MON-87751-7 not available Petition 870260070412, dated 07 / 15 / 2026, p. 21 / 105 12 / 47 Name and Event Code Registered Name Name: MON87751 x MON87701 x MON87708 x MON89788 Code: MON-87751-7 x MON-87701-2 x MON87708 x MON89788 not available Name: MON87769 Code: MON87769-7 not available Name: MON87769 x MON89788 Code: MON-87769-7 x MON-89788-1 not available Name: MON89788 Code: MON-89788-1 Genuity® Roundup Ready 2 Yield™ Name: SYHT0H2 Code: SYN-000H2-5 Herbicide-tolerant soybean line Name: W62 Code: ACS-GM002-9 Liberty Link™ soybean Name: W98 Code: ACS-GM001-8 Liberty Link™ Soya

[0029] In a preferred embodiment of the invention, the use of a compound of formula (I), or a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein pod anomaly comprises symptoms of pod degradation, abnormal seed phenotype and / or stem rust.

[0030] In another preferred embodiment, the pod anomaly manifests itself at the R4 or R5 stage of the reproductive cycle of soybean plants. Petition 870260070412, dated 07 / 15 / 2026, p. 22 / 105 13 / 47 Preferably, the pod anomaly manifests itself in the R5 stage of the reproductive cycle of soybean plants.

[0031] In another preferred embodiment, the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp. and Diaporthe spp. More preferably, the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp. Even more preferably, the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp., wherein the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla and Fusarium spp. Even more preferentially, the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., wherein the Colletotrichum species comprise at least Colletotrichum cliviicola and Colletotrichum truncatum, and Corynespora spp., Diaporthe spp., wherein the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla and Fusarium spp. Even more preferably, the pod anomaly comprises phytopathogenic fungi selected from the group consisting of Cercospora spp., Colletotrichum spp., wherein the Colletotrichum species comprise at least Colletotrichum cliviicola and Colletotrichum truncatum, Corynespora spp., wherein the Corynespora spp. species comprise at least Corynespora cassiicola, Diaporthe spp., wherein the Diaporthe species comprises at least Diaporthe miriciae and Diaporthe longicolla and Fusarium spp. Even more preferentially, the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., wherein the Colletotrichum species comprise at least... Petition 870260070412, dated 07 / 15 / 2026, page 23 / 105 14 / 47 Colletotrichum cliviicola and Colletotrichum truncatum, Corynespora spp., wherein the species of Corynespora spp. comprise at least Corynespora cassiicola, Diaporthe spp., wherein the species of Diaporthe comprise at least Diaporthe miriciae and Diaporthe longicolla, and Fusarium spp., wherein the species of Fusarium spp. comprise at least Fusarium fujikuroi and Fusarium encarnatum.

[0032] In one embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for to control pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp. and Diaporthe spp. Preferably, the pod anomaly comprises selected pathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp.

[0033] In a preferred embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp. and Diaporthe spp., wherein the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla.

[0034] In another preferred embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp. and Diaporthe spp. wherein the Colletotrichum species comprise at least Colletotrichum cliviicola and Colletotrichum truncatum. Petition 870260070412, dated 07 / 15 / 2026, page 24 / 105 15 / 47

[0035] In another preferred embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp. and Diaporthespp. wherein the Corynespora spp. species comprise at least Corynespora cassiicola.

[0036] In another preferred embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp., wherein the Fusarium spp. species comprise at least Fusarium fujikuroi and Fusarium incarnatum.

[0037] Preferably, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp., wherein the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla (more preferably at least Diaporthe longicolla, Diaporthe miriciae, Diaporthe macadamiae and Diaporthe pyracanthae) and the Fusarium spp. species comprise at least Fusarium fujikuroi and Fusarium incarnatum.

[0038] Even more preferably, the use of a compound of formula (I), or a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora Petition 870260070412, dated 07 / 15 / 2026, page 25 / 105 16 / 47 spp., Diaporthe spp. and Fusarium spp., wherein the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla (more preferably at least Diaporthe longicolla, Diaporthe miriciae, Diaporthe macadamiae and Diaporthe pyracanthae), the Colletotrichum species comprise at least Colletotrichum cliviicola and Colletotrichum truncatum and the Fusarium spp. species comprise at least Fusarium fujikuroi and Fusarium incarnatum.

[0039] Even more preferably, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp., wherein the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla (more preferably at least Diaporthe longicolla, Diaporthe miriciae, Diaporthe macadamiae and Diaporthe pyracanthae), the Colletotrichum species comprise at least Colletotrichum cliviicola and Colletotrichum truncatum, the Corynespora spp. species They comprise at least Corynespora cassiicola and species of Fusarium spp. comprise at least Fusarium fujikuroi and Fusarium incarnatum.

[0040] In the present invention, the Diaporthe species, also known as Phomopsis species, are phytopathogenic fungi that may, more preferably, comprise at least one of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. Diaporthe miriciae is also known as Diaporthe ueckeri or Diaporthe ueckerae. The preferred species is Diaporthe miriciae.

[0041] In a preferred embodiment, the species Diaporthe may comprise at least two of the selected species of Diaporthe Petition 870260070412, dated 07 / 15 / 2026, page 26 / 105 17 / 47 miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The two preferred species are Diaporthe miriciae and Diaporthe longicolla.

[0042] In a further preferred embodiment, the species Diaporthe may comprise at least three of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The three preferred species are Diaporthe miriciae, Diaporthe longicolla and Diaporthe masirevicii.

[0043] In a preferred embodiment, the species Diaporthe may comprise at least four of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The four preferred species are Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae.

[0044] In a preferred embodiment, the species Diaporthe may comprise at least five of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The five preferred species are Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii, Diaporthe pyracanthae and Diaporthe sojae.

[0045] In an even more preferred embodiment, the species Diaporthe may comprise Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae.

[0046] In another particular embodiment, the species Diaporthe may comprise at least one of the selected species of Diaporthe miriciae, Diaporthe sojae and Diaporthe macadamiae. More preferably, the species Diaporthe may comprise at least two of the species Petition 870260070412, dated 07 / 15 / 2026, page 27 / 105 18 / 47 selected from Diaporthe miriciae, Diaporthe sojae and Diaporthe macadamiae. Even more preferably, the species Diaporthe may include Diaporthe miriciae, Diaporthe sojae and Diaporthe macadamiae.

[0047] In one embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for to control pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp. and wherein the soybean is a transgenic soybean plant (preferably a transgenic Bt soybean plant, even more preferably, the transgenic soybean plant comprises an event selected from the list consisting of event MON87701, event MON87751, event DAS-81419-2, event DAS-44406-6 / pDAB8264.44.06.1, event DAS-14536-7 / pDAB8291.45.36.2, event DAS-68416-4, event DP-3054231, event DP-356043-5, event FG72, event LL27, event LL55, event EEGM3 / FG72 (optionally stacked with event EE-GM1 / LL27 or event EE-GM2 / LL55), event MON87705, event MON87708, event MON87712, event MON87754, event MON87769, event MON89788, event SYHT0H2 / SYN-000H2-5, event DAS-21606-3, event 8264.44.06.1, event pDAB8291.45.36.2, event pDAB8264.42.32.1, event A2704-12, event A5547-127, event BPS-CV127-91, event GU262, event BPSCV127-9, and event GMB151.).

[0048] In a preferred embodiment of the invention, the use of a compound of formula (I), or a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises phytopathogenic fungi selected from the group consisting of 1 to 15% Corynespora spp., 10 to 70% Diaporthe spp., 5 to 35% Cercospora spp. and 10 to 60% Colletotrichum spp. (the expert will understand that the Petition 870260070412, dated 07 / 15 / 2026, page 28 / 105 19 / 47 The total quantity of phytopathogenic fungi is 100%, and the proportion of percentage values ​​of each species may vary in the pod anomaly disease complex. Preferably, pod anomaly comprises phytopathogenic fungi selected from the group consisting of 1 to 15% Corynespora spp., 10 to 70% Diaporthe spp., 5 to 35% Cercospora spp., and 10 to 60% Colletotrichum spp. and 5 to 20% of Fusarium spp. More preferably, the pod anomaly comprises phytopathogenic fungi selected from the group consisting of 1 to 5% Corynespora spp., 20 to 60% Diaporthe spp., 5 to 20% Cercospora spp., 10 to 30% Colletotrichum spp., and 10 to 20% Fusarium spp.

[0049] In another embodiment of the invention, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling the degradation of seeds in post-harvest soybeans.

[0050] Preferably, the use of a compound of formula (I), or a composition comprising a compound of formula (I), is provided for to control post-harvest seed degradation in soybeans during the soybean growth period.

[0051] In another preferred embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling post-harvest seed degradation in soybeans, wherein the seed comprises selected phytopathogenic fungi from the group consisting of Colletotrichum spp. and Diaporthe spp.

[0052] In another preferred embodiment, the use of a composition comprising a compound of formula (I) is provided for controlling post-harvest seed degradation in soybeans, wherein the composition comprising a compound of formula (I) further comprises at least one fungicidal active compound. More preferably, the at least one fungicidal active compound is selected from the list consisting of azoxystrobin, Petition 870260070412, dated 07 / 15 / 2026, page 29 / 105 20 / 47 cyproconazole, difenoconazole, mancozeb, propiconazole, prothioconazole and pidiflumetofen.

[0053] In another preferred embodiment, the use of a composition comprising a compound of formula (I) to control post-harvest seed degradation in soybeans is provided, wherein the composition comprising a compound of formula (I) further comprises two fungicidal active compounds (preferably the fungicidal active compounds are selected from the list consisting of azoxystrobin, cyproconazole, difenoconazole, mancozeb, propiconazole, propiconazole, propiconazole, propiconazole, propiconazole, propiconazole, prothioconazole and pidiflumethophene). More preferably, the use of a composition comprising a compound of formula (I) to control post-harvest seed degradation in soybeans is provided, wherein the composition comprises a compound of formula (I), prothioconazole and mancozeb.

[0054] Preferably, the use of the compound of formula (I), according to the invention, or a composition thereof, is applied at a rate of 5 to 200 g ai / ha, preferably at a rate of 10 to 100 g ai / ha, more preferably at a rate of 20 to 80 g ai / ha, even more preferably at 25 to 75 g ai / ha, even more preferably at 50 to 75 g ai / ha.

[0055] Preferably, the use of a compound of formula (I), or a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the composition comprising a compound of formula (I) further comprises at least one fungicidal active compound. More preferably, the at least one fungicidal active compound is selected from the list consisting of azoxystrobin, cyproconazole, difenoconazole, mancozeb, propiconazole, prothioconazole and pidiflumethophene. Petition 870260070412, dated 07 / 15 / 2026, p. 30 / 105 21 / 47

[0056] In one embodiment, in which the composition comprises azoxystrobin, azoxystrobin is applied at a rate of 25 to 75 g ai / ha.

[0057] In another embodiment, in which the composition includes cyproconazole, cyproconazole is applied at a rate of 25 to 75 g ai / ha.

[0058] In another embodiment, in which the composition comprises difenoconazole, difenoconazole is applied at a rate of 35 to 115 g ai / ha.

[0059] In another embodiment, in which the composition includes mancozeb, mancozeb is applied at a rate of 500 to 2,000 g ai / ha.

[0060] In another embodiment, in which the composition includes propiconazole, propiconazole is applied at a rate of 25 to 75 g ai / ha.

[0061] In another embodiment, in which the composition comprises prothioconazole, prothioconazole is applied at a rate of 50 to 150 g ai / ha.

[0062] In another embodiment, in which the composition comprises pidiflumethophene, pidiflumethophene is applied at a rate of 25 to 75 g ai / ha.

[0063] In a preferred embodiment, the use of a compound of formula (I), or of a composition comprising a compound of formula (I), is provided for controlling pod anomaly in soybeans, wherein the pod anomaly comprises phytopathogenic fungi selected from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp. and wherein the composition comprising a compound of formula (I) further comprises at least one fungicidal active compound (preferably at least one fungicidal active compound is selected from the list consisting of azoxystrobin, cyproconazole, difenoconazole, mancozeb, propiconazole, prothioconazole and pidiflumethophene).

[0064] In a preferred embodiment, the use of a composition comprising a compound of formula (I) is provided for, to control pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora Petition 870260070412, dated 07 / 15 / 2026, page 31 / 105 22 / 47 spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp. and wherein the composition comprising a compound of formula (I) further comprises two fungicidal active compounds (preferably the fungicidal active compounds are selected from the list consisting of azoxystrobin, cyproconazole, difenoconazole, mancozeb, propiconazole, prothioconazole and pidiflumethophene).

[0065] In a further preferred embodiment, the use of a composition comprising a compound of formula (I) is provided for, to control pod anomaly in soybeans, wherein the pod anomaly comprises selected phytopathogenic fungi from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp. and wherein the composition comprising a compound of formula (I) further comprises prothioconazole and mancozeb (preferably, the compound of formula (I) is applied at a rate of 5 to 200 g ai / ha, more preferably at a rate of 10 to 100 g ai / ha, even more preferably at a rate of 20 to 80 g ai / ha, even more preferably at a rate of 25 to 75 g ai / ha and even more preferably at a rate of 50 to 75 g ai / ha).

[0066] In another embodiment of the invention, the use of a compound of formula (I), or a composition comprising a compound of formula (I), is provided for controlling post-harvest seed degradation in soybeans, wherein the composition comprising a compound of formula (I) further comprises at least one fungicidal active compound (preferably at least one fungicidal active compound is selected from the list consisting of azoxystrobin, cyproconazole, prothioconazole and pidiflumethophene).

[0067] The compound used according to the invention can be used in unmodified form, but is generally formulated in compositions, in various forms, using formulation adjuvants, such as Petition 870260070412, dated 07 / 15 / 2026, page 32 / 105 23 / 47 as carriers, solvents and surfactants. The formulations may be in various physical forms, e.g., in the form of dusting powders, gels, wetting powders, water-dispersible granules, water-dispersible tablets, effervescent granules, emulsifiable concentrates, microemulsifiable concentrates, oil-in-water emulsions, flowable oils, aqueous dispersions, oily dispersions, suspoemulsions, capsule suspensions, emulsifiable granules, soluble liquids, water-soluble concentrates (with water or a water-miscible organic solvent as a carrier), impregnated polymer films or in other known forms, e.g., from the Manual on Development and Use of FAO and WHO Specifications for Pesticides, United Nations, First Edition, Second Revision (2010). Such formulations may be used directly or diluted before use.Dilutions can be made, for example, with water, liquid fertilizers, micronutrients, biological organisms, oil, or solvents.

[0068] The formulations used according to the invention can be prepared, e.g., by mixing the compound of formula (I) (“active ingredient”) with formulation adjuvants in order to obtain compositions in the form of finely divided solids, granules, solutions, dispersions or emulsions. The active ingredient can also be formulated with other adjuvants, such as finely divided solids, mineral oils, vegetable or animal oils, modified vegetable or animal oils, organic solvents, water, surfactants or combinations thereof.

[0069] The active ingredient may also be contained in very fine microcapsules. Microcapsules contain the active ingredient in a porous carrier. This allows the active ingredient to be released into the environment in controlled amounts (e.g., slow release). Microcapsules typically have a diameter of 0.1 to 500 micrometers. They contain the active ingredient in an amount of about 25 to 95% in Petition 870260070412, dated 07 / 15 / 2026, p. 33 / 105 24 / 47 of the capsule weight. The active ingredient may be in the form of a monolithic solid, in the form of fine particles in solid or liquid dispersion, or in the form of a suitable solution. Encapsulation membranes may comprise, for example, natural or synthetic rubbers, cellulose, styrene / butadiene copolymers, polyacrylonitrile, polyacrylate, polyesters, polyamides, polyureas, polyurethane or chemically modified polymers and starch xanthates or other polymers known to those skilled in the art. Alternatively, very fine microcapsules may be formed in which the active ingredient is contained in the form of finely divided particles in a solid matrix of base substance, but the microcapsules are not themselves encapsulated.

[0070] The formulation adjuvants that are suitable for the preparation of the compositions according to the invention are known per se. The following can be used as liquid carriers: water, toluene, xylene, petroleum ether, vegetable oils, acetone, methyl ethyl ketone, cyclohexanone, acid anhydrides, acetonitrile, acetophenone, amyl acetate, 2-butanone, butylene carbonate, chlorobenzene, cyclohexane, cyclohexanol, alkyl esters of acetic acid, diacetone alcohol, 1,2-dichloropropane, diethanolamine, p-diethylbenzene, diethylene glycol, diethylene glycol abietate, diethylene glycol butyl ether, diethylene glycol ethyl ether, diethylene glycol methyl ether, N,N-dimethylformamide, dimethyl sulfoxide, 1,4-dioxane, dipropylene glycol, dipropylene glycol methyl ether, dipropylene glycol dibenzoate, dipropylene glycol, diproxitol. alkylpyrrolidone, ethyl acetate, 2-ethylhexanol, ethylene carbonate, 1,1,1-trichloroethane, 2-heptanone, alpha-pinene, d-limonene, ethyl lactate,ethylene glycol, ethylene glycol butyl ether, ethylene glycol methyl ether, gamma-butyrolactone, glycerol, glycerol acetate, glycerol diacetate, glycerol triacetate, hexadecane, hexylene glycol, isoamyl acetate, isobornyl acetate, isooctane, isophorone, isopropylbenzene, isopropyl myristate, lactic acid, lauryl sulfate, oxide of, Petition 870260070412, dated 07 / 15 / 2026, page 34 / 105 25 / 47 mesityl, methoxypropanol, methyl isoamyl ketone, methyl isobutyl ketone, methyl laurate, methyl octanoate, methyl oleate, methylene chloride, m-xylene, n-hexane, n-octylamine, octadecanoic acid, octylamine acetate, oleic acid, oleylamine, o-xylene, phenol, polyethylene glycol, propionic acid, propyl lactate, propylene carbonate, propylene glycol, propylene glycol methyl ether, p-xylene, toluene, triethyl phosphate, triethylene glycol, xylenesulfonic acid, paraffin, mineral oil, trichloroethylene, perchloroethylene, ethyl acetate, amyl acetate, butyl acetate, propylene glycol methyl ether, diethylene glycol methyl ether, methanol, ethanol, isopropanol and alcohols of higher molecular weight, such as amyl alcohol, tetrahydrofurfuryl alcohol, hexanol, octanol, ethylene glycol, propylene glycol, glycerol, N-methyl-2-pyrrolidone and the like.

[0071] Suitable solid carriers are, for example, talc, titanium dioxide, pyrophyllite clay, silica, attapulgite clay, kieselguhr, limestone, calcium carbonate, bentonite, calcium montmorillonite, cottonseed husks, wheat flour, soybean flour, pumice, wood flour, crushed walnut shells, lignin and similar substances.

[0072] A large number of surfactants can be advantageously used in both solid and liquid formulations, especially in those formulations that can be diluted with a carrier before use. Surfactants can be anionic, cationic, nonionic, or polymeric and can be used as emulsifiers, wetting agents, or suspending agents, or for other purposes. Typical surface-active substances include, for example, alkyl sulfate salts, such as diethanolammonium lauryl sulfate; alkylaryl sulfonate salts, such as calcium dodecylbenzene sulfonate; alkylphenol / alkylene oxide addition products, such as nonylphenol ethoxylate; alcohol / alkylene oxide addition products, such as tridecyl alcohol ethoxylate; soaps, such as sodium stearate; salts of Petition 870260070412, dated 07 / 15 / 2026, page 35 / 105 26 / 47 alkylnaphthalenesulfonates, such as sodium dibutylnaphthalenesulfonate; dialkyl esters of sulfosuccinate salts, such as sodium di(2-ethylhexyl)sulfosuccinate; sorbitol esters, such as sorbitol oleate; quaternary amines, such as lauryltrimethylammonium chloride; polyethylene glycol esters of fatty acids, such as polyethylene glycol stearate; block copolymers of ethylene oxide and propylene oxide; and salts of mono- and di-alkyl phosphate esters; and also additional substances described, e.g., in McCutcheon's Detergents and Emulsifiers Annual, MC Publishing Corp., Ridgewood, New Jersey (1981).

[0073] Additional adjuvants that may be used in pesticide formulations include crystallization inhibitors, viscosity modifiers, suspending agents, colorants, antioxidants, foaming agents, light absorbers, mixing aids, antifoaming agents, complexing agents, pH neutralizing or modifying substances and buffers, corrosion inhibitors, fragrances, wetting agents, absorption enhancers, micronutrients, plasticizers, glidants, lubricants, dispersants, thickeners, antifreeze, microbicides and liquid and solid fertilizers.

[0074] The compositions used according to the invention may include an additive comprising a vegetable or animal oil, a mineral oil, alkyl esters of such oils, or mixtures of such oils and oil derivatives. The amount of oil additive in the composition according to the invention is generally from 0.01 to 10%, based on the active ingredient to be applied. For example, the oil additive may be added to a spray tank at the desired concentration after a spray mixture has been prepared. Preferred oil additives comprise mineral oils or a vegetable oil, for example rapeseed oil, olive oil or sunflower oil, emulsified vegetable oil, alkyl esters of vegetable oils, for example methyl derivatives, Petition 870260070412, dated 07 / 15 / 2026, p. 36 / 105 27 / 47 or an oil of animal origin, such as fish oil or beef tallow. Preferred oil additives comprise alkyl esters of C8-C22 fatty acids, especially methyl derivatives of C12-C18 fatty acids, for example, methyl esters of lauric acid, palmitic acid and oleic acid (methyl laurate, methyl palmitate and methyl oleate, respectively). Many oil derivatives are known from the Compendium of Herbicide Adjuvants, 10th Edition, Southern Illinois University, 2010.

[0075] The compositions generally comprise from 0.1 to 99% by weight, especially from 0.1 to 95% by weight, of the compound of the present invention and from 1 to 99.9% by weight of a formulation adjuvant, which preferably includes from 0 to 25% by weight of a surfactant. Although commercial products may preferably be formulated as concentrates, the end user will normally employ diluted formulations.

[0076] As a general guideline, the spray volume of a composition comprising the compound of formula (I) may be applied from 1 to 2000 L / ha, preferably from 10 to 1000 L / ha and more preferably from 20 to 200 L / ha. In a particular embodiment, the spray volume of a composition comprising the compound of formula (I) may be applied from 100 to 200 L / ha for soil application or from 20 to 40 L / ha for aerial application.

[0077] Preferred formulations may have the following compositions (% by weight): Emulsifiable concentrates: Active ingredient: Surfactant: Liquid carrier: Dust: active ingredient: 95%, preferably 60 to 90% 30%, preferably 5 to 20% 80%, preferably 1 to 35% 0.1 to 10%, preferably 0.1 to 5% Petition 870260070412, dated 07 / 15 / 2026, p. 37 / 105 28 / 47 solid conveyor: 99.9 to 90%, preferably 99.9 to 99% Suspended concentrates: Active ingredient: 5 to 75%, preferably 10 to 50%; Water: 94 to 24%, preferably 88 to 30%; Surfactant: Wettable powders: Active ingredient: Surfactant: Solid carrier: Granules: Active ingredient: Solid carrier: 40%, preferably 2 to 30% 0.5 to 90%, preferably 1 to 80% 0.5 to 20%, preferably 1 to 15% to 95%, preferably 15 to 90% 0.1 to 30%, preferably 0.1 to 15% 99.5 to 70%, preferably 97 to 85%.

[0078] The following Examples in Table 2 further illustrate, but do not limit, the invention. Table 2 Wettable powders a) b) c) active ingredient 25% 50% 75% sodium lignosulfonate 5% 5% - sodium lauryl sulfate 3% - 5% sodium diisobutylnaphthalenesulfonate - 6% 10% polyethylene glycol phenolic ether - 2% - (7-8 mol of ethylene oxide) highly dispersed silicic acid 5% 10% 10% Kaolin 62% 27% -

[0079] The combination is thoroughly mixed with the adjuvants and the mixture is completely ground in a suitable mill, resulting in wettable powders that can be diluted with water to give suspensions of the desired concentration, as per the data in Table 3. Table 3 Petition 870260070412, dated 07 / 15 / 2026, page 38 / 105 29 / 47 Powders for dry seed treatment a) b) c) active ingredient 25% 50% 75% light mineral oil 5% 5% 5% highly dispersed silicic acid 5% 5% - Kaolin 65% 40% - Talc - 20

[0080] The combination is thoroughly mixed with the adjuvants and the mixture is thoroughly ground in a suitable mill, providing powders that can be used directly for seed treatment, as per the data in Table 4. Table 4 Emulsifiable concentrate, active ingredient 10%, octylphenolic ether of polyethylene glycol 3% (4-5 mol of ethylene oxide), calcium dodecylbenzenesulfonate 3%, polyglycol ether of castor oil (35 mol of ethylene oxide) 4%, cyclohexanone 30%, xylene mixture 50%.

[0081] Emulsions of any required dilution, which can be used in plant protection, can be obtained from this concentrate by dilution with water, as per the data in Table 5. Table 5 Petition 870260070412, dated 07 / 15 / 2026, page 39 / 105 30 / 47 Dusts a) b) c) active ingredient 5% 6% 4% Talc 95% - - Kaolin - 94% - mineral filler - - 96%

[0082] Ready-to-use dusts are obtained by mixing The mixture is combined with a conveyor and ground in a suitable mill, as per the data in Table 6. Such powders can also be used for dry seed coatings. Table 6 Extruder granules, active ingredient: 15% sodium lignosulfonate, 2% carboxymethylcellulose, 1% kaolin, 82%.

[0083] The mixture is mixed and ground with the adjuvants and the mixture is moistened with water, as per the data in Table 7. The mixture is extruded and then dried in an air stream. Table 7 Coated granules, active ingredient 8% polyethylene glycol (mol. wt. 200), 3% kaolin 89%.

[0084] The finely ground mixture is uniformly applied, in a mixer, to the kaolin moistened with polyethylene glycol, according to the data in Table 8. Dust-free coated granules are obtained in this way. Concentrate in suspension Table 8 Petition 870260070412, dated 07 / 15 / 2026, page 40 / 105 31 / 47 Active ingredient: 40% propylene glycol, 10% polyethylene glycol nonylphenolic ether (15 mol ethylene oxide), 6% sodium lignosulfonate, 10% carboxymethylcellulose, 1% silicone oil (in the form of a 75% emulsion in water), 1% water, 32%

[0085] The finely ground mixture is intimately mixed with the adjuvants, resulting in a suspension concentrate from which suspensions of any desired dilution can be obtained by dilution with water, as per the data in Table 9. Using such dilutions, live plants, as well as plant propagation material, can be treated and protected against infestation by microorganisms by spraying, pouring or immersion. Concentrate suitable for flowable application in seed treatment. Table 9 Active ingredient: 40% propylene glycol, 5% butanol copolymer PO / EO, 2% tristyrenephenol with 10-20 moles of EO, 2% 1,2-benzisothiazolin-3-one (as a 20% solution in water), 0.5% calcium salt of monoazo pigment, 5% silicone oil (as a 75% emulsion in water), 0.2% water, 45.3% Petition 870260070412, dated 07 / 15 / 2026, page 41 / 105 32 / 47

[0086] The finely ground mixture is intimately mixed with the adjuvants, resulting in a suspension concentrate from which suspensions of any desired dilution can be obtained by dilution with water. Using such dilutions, live plants, as well as plant propagation material, can be treated and protected against infestation by microorganisms by spraying, pouring or immersion. Slow-Release Capsule Suspension

[0087] 28 parts of the compound of the invention are mixed with 2 parts of an aromatic solvent and 7 parts of a mixture of toluene diisocyanate / polymethylene-polyphenylisocyanate (8:1). This mixture is emulsified in a mixture of 1.2 parts polyvinyl alcohol, 0.05 parts an antifoaming agent, and 51.6 parts water until the desired particle size is achieved. To this emulsion is added a mixture of 2.8 parts 1,6-diaminohexane in 5.3 parts water. The mixture is stirred until the polymerization reaction is complete. The resulting capsule suspension is stabilized by adding 0.25 parts a thickener and 3 parts a dispersing agent. The capsule suspension formulation contains 28% of the active ingredient. The average diameter of the capsules is 8-15 micrometers. The resulting formulation is applied to seeds as an aqueous suspension in an apparatus suitable for this purpose.

[0088] The amount of a compound, according to the invention, to be applied will depend on several factors, such as the target of the treatment, such as, for example, plants, soil or seeds; the type of treatment, such as, for example, spraying, dusting or seed coating; the purpose of the treatment, such as, for example, prophylactic or therapeutic; or the time of application.

[0089] The compound of formula (I) (active ingredient) can be applied at a rate of 5 to 500 g of active ingredient (ai) / ha, preferably at a rate of 5 to 200 g ai / ha and, more preferably, Petition 870260070412, dated 07 / 15 / 2026, p. 42 / 105 33 / 47 at a rate of 10 to 100 g ai / ha, such as at a rate of 30, 40, 50 or 75 g ai / ha.

[0090] When the composition according to the invention is used for seed treatment, doses of 0.001 to 100 g of a compound of formula (I) per kg of seed, preferably 0.001 to 50 g per kg of seed, are generally sufficient, and more preferably 0.01 to 10 g per kg of seed.

[0091] The compositions and formulations of the present invention may include the compound of formula (I) as the sole active ingredient in the compositions or formulations, or may also be used in combination with other active ingredients, for example, other fungicides and / or insecticides and / or acaricides and / or nematocides and / or molluscicides and / or biological products and / or plant growth regulators.

[0092] Normally, in crop management, a farmer will use one or more active ingredients in addition to the compound of the present invention. Examples of active ingredients include other fungicides and / or insecticides and / or acaricides and / or nematocides and / or molluscicides and / or biological products and / or plant growth regulators.

[0093] For example, the compound of the present invention can be used in combination with another fungicide, as detailed in WO 2008 / 131901. In particular, the compound of formula (I), according to the present invention, can be used in combination with a strobilurin fungicide (e.g., azoxystrobin, picoxystrobin, trifloxystrobin), a triazole fungicide (e.g., cyproconazole, difenoconazole, propiconazole, prothioconazole, tebuconazole, mefentrifluconazole), a multi-site fungicide (e.g., chlorothalonil, copper oxychloride, mancozeb, fluazinam) and / or an SDHI fungicide (e.g., bixafen, fluxapyroxad, pidiflumethophene, inpirfluxam, izopyrazam, fluxapyroxad). Petition 870260070412, dated 07 / 15 / 2026, page 43 / 105 34 / 47

[0094] In the present invention, the term "locus," as used herein, means fields in or on which plants are growing or where seeds of cultivated plants are sown or where seed will be placed in the soil. It includes soil, seeds and seedlings, as well as established vegetation.

[0095] The term “plants” refers to all the physical parts of a plant, including seeds, seedlings, cuttings, roots, tubers, stems, trunks, foliage, and fruits.

[0096] The term “plant propagation material” is understood to denote all plant-generating parts, such as seeds, that can be used for the multiplication of the latter, including vegetative plant material, such as cuttings. Plant propagation material may include seeds (in the strict sense), roots, fruits, tubers, bulbs, rhizomes, and plant parts. Germinated plants and young plants that are to be transplanted after germination or emergence from the soil may also be mentioned. These young plants may be protected, before transplanting, by total or partial immersion treatment. The plant propagation material may be treated with the compound of formula (I), or with the composition of the invention, before the material is sown or planted. Alternatively, the plant propagation material may be treated with the compound of formula (I), or with the composition of the invention, during sowing or planting.Additionally, the compound of formula (I), or the composition of the invention, can be applied to previously treated propagation material before, or during, its planting. The compound of formula (I), or the composition of the invention, can be applied during seed sowing. The compound of formula (I), or the composition, can also be used to plant plant propagation material derived from plants grown in a greenhouse and / or during transplanting. More. Petition 870260070412, dated 07 / 15 / 2026, page 44 / 105 35 / 47 Preferably, the plant propagation material is plant seeds. Seed treatment can occur on unsown seed, and the term “unsown seed” is intended to include seed at any time between seed collection and sowing of the seed in the soil for the purpose of germination and plant growth. Treatment of an unsown seed is not intended to include those practices in which the compound of formula (I), or the composition of the invention, is applied to the soil but would include any application practice targeting the seed during the sowing / planting process. The treated plant propagation material of the present invention can be treated in the same manner as conventional plant propagation material. The treated propagation material can be stored, handled, planted and tillered in the same manner as any other pesticide-treated material.

[0097] Another objective of the present invention relates to a use of the compound of formula (I), as defined in the present invention, or of the composition comprising a compound of formula (I), as defined in the present invention, to control Diaporthe species in soybeans.

[0098] The Diaporthe species are phytopathogenic diseases, as described in the present invention, and may, more preferably, comprise at least one of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The preferred species is Diaporthe miriciae.

[0099] In a preferred embodiment, the species Diaporthe may comprise at least two of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The two preferred species are Diaporthe miriciae and Diaporthe longicolla. Petition 870260070412, dated 07 / 15 / 2026, page 45 / 105 36 / 47

[0100] In a further preferred embodiment, the species Diaporthe may comprise at least three of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The three preferred species are Diaporthe miriciae, Diaporthe longicolla and Diaporthe masirevicii.

[0101] In a preferred embodiment, the species Diaporthe may comprise at least four of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The four preferred species are Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae.

[0102] In a preferred embodiment, the species Diaporthe may comprise at least five of the selected species of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae. The five preferred species are Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii, Diaporthe pyracanthae and Diaporthe sojae.

[0103] In an even more preferred embodiment, the species Diaporthe may comprise Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae.

[0104] In another particular embodiment, the species Diaporthe may comprise at least one of the selected species of Diaporthe miriciae, Diaporthe sojae and Diaporthe macadamiae. More preferably, the species Diaporthe may comprise at least two of the selected species of Diaporthe miriciae, Diaporthe sojae and Diaporthe macadamiae. Even more preferably, the species Diaporthe may comprise Diaporthe miriciae, Diaporthe sojae and Diaporthe macadamiae. Petition 870260070412, dated 07 / 15 / 2026, page 46 / 105 37 / 47

[0105] Several aspects and embodiments of the present invention will now be illustrated in more detail, by way of example, and the following Figures in which: Figure 1 shows the EC50 on a log scale (mg / L of active ingredient), where AI1 is the compound of formula (I), according to the present invention, and AI2 to AI5 are comparative active ingredients.

[0106] According to the Fungicide Resistance Action Committee (FRAC), EC50 is defined as the dose of fungicide that inhibits growth by 50%, when compared to an unmodified control.

[0107] Compounds AI1 to AI5 belong to the succinate dehydrogenase inhibitors (SDHI). EXAMPLES

[0108] In Figure 1: - AI1 refers to benzovindiflupir as the active ingredient, marketed by Syngenta AG under the name Elatus®Plus, which is an EC100 formulation (emulsifiable concentrate with 100 g of active ingredient per liter); - AI2 refers to isopyrazam as the active ingredient, marketed by Adama Ltd under the name Reflect®, which is an EC125 formulation (emulsifiable concentrate with 125 g of active ingredient per liter); - AI3 refers to bixaphene as the active ingredient, marketed by Bayer CropScience AG under the name Thore®, which is an EC125 formulation (emulsifiable concentrate with 125 g of active ingredient per liter); - AI4 refers to Impirfluxam as the active ingredient, marketed by Sumitomo Chemical under the name Excalia®, which is an SC313 formulation (concentrated suspension with 313 g of active ingredient per liter); and Petition 870260070412, dated 07 / 15 / 2026, page 47 / 105 38 / 47 - AI5 refers to fluxapyroxad as the active ingredient, marketed by BASF SE under the name Sercadis®, which is an SC300 formulation (concentrated suspension with 300 g of active ingredient per liter).

[0109] Test preparation was carried out as follows: Isolates of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Diaporthe masirevicii and / or Diaporthe pyracanthae from soybean were collected in Mato Grosso (3) and Mato Grosso do Sul (1).More specifically, the isolates comprised at least Diaporthe miriciae, more particularly they comprised at least Diaporthe miriciae and Diaporthe longicolla, more particularly they comprised at least Diaporthe miriciae, Diaporthe longicolla and Diaporthe masirevicii, more particularly they comprised at least Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae, more particularly they comprised at least Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii, Diaporthe pyracanthae and Diaporthe sojae, and even more particularly they comprised Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii, Diaporthe pyracanthae, Diaporthe sojae and Diaporthe macadamiae.

[0110] All isolates collected in the 2022 growing seasons were isolated from pods with pod anomaly symptoms. Isolation was performed directly. Mycelial fungal fragments were removed from pods and transferred to Petri dishes containing potato dextrose-agar (PDA) culture medium (4 gL-1 potato extract, 20 gL-1 dextrose, 15 gL-1 agar, pH 5.6 ± 0.2).

[0111] The isolates were cultured in PDA culture medium at 22 °C under a 12 h / 12 ​​h photoperiod for 7 days. Split Petri dishes measuring 9 mm x 15 mm were used. Each isolate was composed of 4 replicates. Mycelial discs with a 4 mm diameter from the edge of the colonies were transferred to Petri dishes containing PDA medium modified by Petition 870260070412, dated 07 / 15 / 2026, page 48 / 105 39 / 47 fungicide. Petri dishes with PDA without fungicide treatment were used as a control.

[0112] Serial dilutions of 0.01, 0.05, 0.01, 0.1, 1.0, 10.0 and 100 mg.L-1 of each AI (AI1 to AI5) were diluted in sterile distilled water and homogenized in PDA culture medium.

[0113] Subsequently, the Petri dishes were incubated at 24 °C ± 2 °C and a 12 h / 12 ​​h photoperiod for 5 days, and the diameter of each colony was measured (orthogonal measurements) for each isolate to determine the percentage of control by each fungicide, compared to growth in unmodified medium, following the methodology described by Ishii et al., 2009. The percentage control by the fungicide was calculated from growth in modified medium, compared to growth in PDA (Mello et al., 2021). EC50 graphical analysis was performed using TIBCO® Spotfire® Analyst software (version 10.3).

[0114] The results from Figure 1 are summarized in Table 10 below. Table 10 EC50 (mg / L) AI1 AI2 AI3 AI4 AI5 Median 0.38 2.38 3.37 11.46 23.20 Min 0.10 1.00 2.56 4.48 9.08 Max 0.59 12.53 15.06 22.00 100.00

[0115] The results in the 1st table 10 clearly show that Surprisingly, only a very small amount of compound formula (I) (0.38 mg / L) is needed to control 50% of the pests, compared with the other active ingredients of SDHI, AI2 to AI5.

[0116] Similar tests were carried out in 2023, following the same protocol described above, knowing that isolates of Diaporthe miriciae, Diaporthe sojae, Diaporthe macadamiae, Diaporthe longicolla, Petition 870260070412, dated 07 / 15 / 2026, page 49 / 105 40 / 47 Diaporthe masirevicii and / or Diaporthe pyracanthae from soybean were collected in Rondônia (n = 3) and Mato Grosso (n = 16). More specifically, the isolates comprised at least Diaporthe miriciae, more particularly comprised at least Diaporthe miriciae and Diaporthe longicolla, more particularly comprised at least Diaporthe miriciae, Diaporthe longicolla and Diaporthe masirevicii, more particularly comprised at least Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii and Diaporthe pyracanthae, more particularly included at least Diaporthe miriciae and Diaporthe longicolla, Diaporthe masirevicii, Diaporthe pyracanthae and Diaporthe sojae, and even more particularly included Diaporthe miriciae, Diaporthe longicolla, Diaporthe masirevicii, Diaporthe pyracanthae, Diaporthe sojae and Diaporthe macadamiae.

[0117] The results are compiled in Table 11 below. Table 11 EC50 (mg / L) AI1 AI3 AI4 AI5 Median 1.8 4.3 43.4 68.9 Min 0.3 0.7 2.2 6.1 Max 11.1 69.0 100.0 100.0

[0118] The results in Table 11 clearly show that only a very low amount of compound formula (I) (1.8 mg / L) is surprisingly needed to control 50% of the pests, compared with the other active ingredients of SDHI, AI3 to AI5.

[0119] Other isolates were collected in the 2021 / 2022, 2022 / 2023, and 2023 / 2024 growing seasons from pods with pod anomaly symptoms throughout Brazil. Samples were morphologically diagnosed based on the observation of fungal structures. Isolates were recovered from symptomatic soybean tissue by cutting a small piece of the damaged plant tissue. This material was introduced into medium Petition 870260070412, dated 07 / 15 / 2026, page 50 / 105 41 / 47 PDA. Approximately 14 days after isolation, the fungal colonies were evaluated according to their morphology. All isolates were identified using molecular tools.

[0120] In order to investigate the relationship of these fungi with the symptoms of pod anomaly, Koch's postulate was carried out. After 21 days, under controlled conditions, the inoculated plants showed the first symptoms. Confirmation of pathogenicity occurred with the re-isolation of fungi recovered from soybean plants inoculated with the pathogens.

[0121] With the aim of demonstrating the effect of a compound of formula (I) to control Diaporthe spp. and Colletotrichum spp., the mycelial growth inhibition test was performed. To test the in vitro efficacy of the carboxamides, the isolates were randomly selected. Among the carboxamides tested, the fungicide benzovindiflupir showed the highest intrinsic activity for both fungi. Molecular identification was performed as follows:

[0122] Sanger sequencing was used for sequencing and analysis of fungal isolates. The sequenced genomic regions used in the analysis were the internal transcribed spacer of ribosomal DNA (ITS-rDNA) and tubulin 2 (TUB2), histone 3 (HIS3), chitin synthase (CHS1), glutamine synthetase (GS), translation elongation factor 1 (TEF1) and actin genes (ACT).

[0123] Concatenated analysis of isolate sequences, together with sequences deposited by GenBank-NCBI, was used for the correct and precise identification of the species of each isolate.

[0124] Symptomatic soybeans with 'pod anomaly' were sampled and isolations made from 20 pods during the 2021 / 2022 growing season demonstrate a complex of fungal pathogens involved in the pods and are described in Table 12 below. Petition 870260070412, dated 07 / 15 / 2026, page 51 / 105 42 / 47 Table 12 Proportion of Pathogen Species (%) 2021 / 22 Season N= 20% Diaporthe spp 16% Colletotrichum spp 48% Cercospora spp 33% Corynespora spp 3%

[0125] Symptomatic soybeans with 'pod anomaly' were sampled and isolations made from 254 pods and 176 stems from the 2022 / 2023 growing season demonstrate a complex of fungal pathogens involved in the pods and are described in Table 13 below. Table 13 Proportion of Pathogen Species (%) 2022 / 23 Season N= 430 Stem (%) Pods (%) Diaporthe spp 28 23 Colletotrichum spp 22 27 Cercospora spp 7 18 Corynespora spp 1 13 Fusarium spp 16 10 Others 26 9 Petition 870260070412, dated 07 / 15 / 2026, page 52 / 105 43 / 47

[0126] Table 14 below describes a further analysis of the data from Table 13 and of 47 isolates of Colletotrichum spp, two main species are indicated, Colletotrichum clivicola and Colletotrichum truncatum. Table 14 Identification and proportion (%) of molecular species of Colletotrichum spp. from the 2022 / 23 season: N=47 Stem, N=27 Pods, N=20 Colletotrichum clivicola 7 50 Colletotrichum truncatum 93 50

[0127] Table 15 below describes a further analysis of the data from Table 13 and of 66 isolates of Diaporthe spp., some species are indicated, Diaporthe longicolla, Diaporthe Ueckerae, Diaporthe macadamiae and Diaporthe pyracanthae. These results confirm that the species responsible for stem canker are different from those associated with pod anomaly. Table 15 Identification and proportion (%) of molecular species of Diaporthe spp from the 2022 / 23 season N= 66 Stem N=50 Pods N=11 Immature Grain N = 5 Diaporthe longicolla 34 9 40 Petition 870260070412, dated 07 / 15 / 2026, page 53 / 105 44 / 47 Diaporthe Ueckerae 60 91 60 Diaporthe macadamiae 2 0 0 Diaporthe pyracanthae 4 0 0

[0128] Table 16 below describes a further analysis of the data from Table 13 and of 38 isolates of Fusarium spp., some species are indicated, F. oxysporum spp complex, F. fujikuroi spp complex and F. incarnatum-equiseti spp complex. Table 16 Identification and proportion (%) of molecular species of Fusarium spp from the 2022 / 23 season: N= 38 Stem N=24 Pods N=14 F. oxysporum spp complex 4 0 F. fujikuroi spp complex 4 21 F. incarnatum equiseti spp complex 92 79

[0129] Symptomatic soybeans with 'pod anomaly' were sampled and isolations made from 80 pods from the 2023 / 2024 growing season demonstrate a complex of fungal pathogens involved in the pods and are described in Table 17 below. Table 17 Percentage of Pathogen Species Season 2023 / 24 N= 80 Diaporthe spp 50.8 Petition 870260070412, dated 07 / 15 / 2026, page 54 / 105 45 / 47 Colletotrichum spp 16.9 Cercospora spp 11.9 Corynespora spp 3.4 Fusarium spp 16.9

[0130] To evaluate the effect of a compound of formula (I) (benzovindiflupir) on seed degradation (caused by pod anomaly) in post-harvest soybeans, the following procedure was followed.

[0131] After harvesting, soybean grains / seeds were collected and stored in a large bag under ambient conditions (25 °C) for a period of 5 months. For each treatment method, 100 g of grains / seeds were weighed from the large bag randomly at monthly intervals. To assess the impact of pod anomaly on the seeds, the seeds were classified and separated into good / healthy and infected / degraded seeds every month for each treatment method, and after each monthly assessment these grains / seeds were returned to the same large bag. The results of this analysis are presented in Table 18 below. Table 18 List of Treatments % of grains infected by seed degradation (caused by pod anomaly) under post-harvest conditions March 23 April 23 May 23 June 23 July 23 No treatment 21 21 28 35 37 FoxXpro®1 (BIX+PTZ+TFS): 500 mL / ha + Unizeb Gold® (MZB): 1.5 kg / ha 6 6 13 22 26 Petition 870260070412, dated 07 / 15 / 2026, p. 55 / 105 46 / 47 Blavity®2 (FXD+PTZ): 250 mL / ha + Unizeb Gold® (MZB): 1.5 kg / ha 13 14 26 27 28 Evolution® (AZT+PTZ+MZB)3: 2.0 L / ha 10 10 20 20 23 Mitrion® (STL+PTZ): 450 mL / ha Unizeb Gold® (MZB): 1.5 kg / ha 4 6 13 14 15 1Combined with Aureo® adjuvant at 400 mL / ha2Combined with Mess® adjuvant at 375 mL / ha3Combined with Strides® adjuvant at 375 mL / ha

[0132] After 5 months in storage conditions, the grains were further analyzed to identify the fungal pathogens present. 25 seeds that showed symptoms of pod anomaly were placed in a sterilized acrylic box containing two absorbent papers moistened with deionized water for humidity. The seeds were placed randomly, approximately 1 cm apart, and kept in a temperature-controlled environment (20 °C) and protected from light. After approximately 7 days, these pathogens in each seed were identified using the same methodology described above. The results are summarized in Table 19 below and were similar to the previous data obtained above for the stem and pods: Table 19 Percentage of pathogen species in grains infected by anomaly, 2023 / 24 season, Grains N=6 Petition 870260070412, dated 07 / 15 / 2026, page 56 / 105 47 / 47 Diaporthe spp 83 Colletotrichum spp 17 Abbreviations used in Table 18: AZT = Azoxystrobin BIX = Bixaphene FXD = Fluxapyroxade MZB = Mancozeb PTZ = Protioconazole STL = Benzovindiflupir Petition 870260070412, dated 07 / 15 / 2026, page 57 / 105

Claims

1 / 3 CLAIMS 1. Use of a compound of formula (I) or of a composition comprising a compound of formula (I), characterized in that it is for controlling pod anomaly in soybeans.

2. Use, according to claim 1, characterized in that the pod anomaly comprises symptoms of pod degradation, abnormal seed phenotype and / or stem rust.

3. Use, according to claim 1 or 2, characterized in that the pod anomaly manifests itself at stage R4 or R5 of the reproductive cycle of soybean plants.

4. Use, according to any one of claims 1 to 3, characterized in that the pod anomaly comprises phytopathogenic fungi selected from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp. and Diaporthe spp.

5. Use, according to any one of claims 1 to 4, characterized in that the pod anomaly comprises phytopathogenic fungi selected from the group consisting of Cercospora spp., Colletotrichum spp., Corynespora spp., Diaporthe spp. and Fusarium spp.

6. Use, according to claim 4 or 5, characterized in that the Diaporthe species comprise at least Diaporthe miriciae and Diaporthe longicolla. Petition 870250072078, dated 08 / 15 / 2025, pp. 158 / 161 2 / 3 7. Use, according to any one of claims 4 to 6, characterized in that the Colletotrichum species comprise at least Colletotrichum cliviicola and Colletotrichum truncatum.

8. Use, according to any one of claims 4 to 7, characterized in that the Corynespora spp. species comprise at least Corynespora cassiicola.

9. Use according to claim 5, characterized in that the Fusarium spp. species comprise at least Fusarium fujikuroi and Fusarium encarnatum.

10. Use of a compound of formula (I) or of a composition comprising a compound of formula (I), characterized in that it is for controlling post-harvest seed degradation in soybeans.

11. Use, according to any one of claims 1 to 10, characterized in that the compound of formula (I) is applied to soybeans at a rate of 5 to 200 g ai / ha.

12. Use, according to any one of claims 1 to 11, characterized in that the soybean is a transgenic soybean plant.

13. Use, according to any one of claims 1 to 12, characterized in that the composition comprising a Petition 870250072078, dated 08 / 15 / 2025, page 159 / 161 3 / 3 compound of Formula (I) further comprises at least one fungicidal active compound.

14. Method for combating, preventing or controlling pod anomalies in soybeans, characterized in that it comprises applying to the soybean crop, its locus or its propagation material, a compound of formula (I), or a composition comprising a compound of formula (I).

15. Method for combating, preventing or controlling post-harvest seed degradation in soybeans, characterized in that it comprises applying to the soybean crop, its locus or its propagation material, a compound of formula (I), or a composition comprising a compound of formula (I). Petition 870250072078, dated 15 / 08 / 2025, pp. 160 / 161

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