Intraocular lens with power factor and structure to improve peripheral vision.
Patent Information
- Application Number
- BR112025020937
- Authority / Receiving Office
- BR · BR
- Patent Type
- Applications
- Publication Date
- 2026-08-25
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Description
1 / 53 “Intraocular lens with power factor and structure to improve peripheral vision” FIELD OF THE INVENTION
[0001] The embodiments of the present invention relate to apparatus, systems and methods for manufacturing intraocular lenses that provide corrective vision with improvements to peripheral vision as well. BACKGROUND
[0002] The embodiments of the present invention relate to vision treatment techniques and, in particular, to ophthalmic lenses, such as intraocular lenses (IOLs), including, for example, phakic intraocular lenses and piggyback intraocular lenses (i.e., intraocular lenses implanted in an eye that already has an intraocular lens).
[0003] Intraocular lenses (IOLs) can be used to restore visual performance after a cataract or other ophthalmic procedure in which the natural crystalline lens is replaced or supplemented by the implantation of an intraocular lens. When such a procedure alters the optics of the eye, one goal is usually to improve central vision. Recent studies have found that when a monofocal intraocular lens is implanted, peripheral aberrations are altered, and that these aberrations differ significantly from those of normal phakic eyes. The predominant change is observed in relation to peripheral astigmatism, which is the main peripheral aberration in the natural eye, followed by sphere and then higher-order aberrations. Such changes can have an impact on overall functional vision, including the ability to drive, fall risk, postural stability, and / or detection ability.
[0004] There are also certain retinal conditions that reduce central vision, such as age-related macular degeneration (AMD) or a central scotoma. Other diseases can affect central vision, even at a very young age, such as Stargardt disease, the disease Petition 870250103047, dated 11 / 11 / 2025, p. 7 / 75 2 / 53 of Best and reverse retinitis pigmentosa. The visual outcome for patients suffering from these conditions can be improved by enhancing peripheral vision.
[0005] Peripheral vision can also be impaired by glaucoma. Glaucoma affects 2% of the population over 40 years of age. Patients with glaucoma gradually lose peripheral vision as a result of damage to the optic nerve. Central vision may degrade in very advanced stages of the disease. Significant disabilities in daily life can occur due to glaucoma, including problems with walking, balance, risk of falls, and driving. Patients suffering from glaucoma may benefit from intraocular lenses that improve both central and peripheral vision.
[0006] In light of the above, lenses that improve peripheral vision are necessary. BRIEF SUMMARY
[0007] The present invention solves the above problems by providing lenses with power format factor and diopter marking power ranges that correspond to lenses with optimized on-axis visual acuity and contrast sensitivity and with a blur parameter less than 1.8 diopters (D), which therefore improve peripheral vision. Furthermore, lenses are provided with format factors and diopter marking powers that fall within sub-ranges corresponding to an optimal peripheral vision lens that minimizes off-axis astigmatism to 20 degrees of eccentricity while maximizing on-axis visual acuity and contrast sensitivity, and the optimization parameters are described herein.
[0008] In particular, a first embodiment of an intraocular lens comprises a lens body, wherein the lens body comprises: a refractive index between 1.40 and 1.50 inclusive, a diopter marking power between 17 D and 23 D inclusive, and a factor Petition 870250103047, dated 11 / 11 / 2025, page 8 / 75 3 / 53 of power format that is less than or equal to -1.0 and greater than or equal to -2.5. Advantageously, providing an intraocular lens according to the marking power range and the power format factor range of the first modality allows for the correction of peripheral astigmatism according to a blur parameter less than 1.8 D, while optimizing visual acuity on the axis. Within these ranges, the power format factor is stable, meaning that structural features can be selected to produce lenses that are predictably capable of producing the effect of reducing off-axis astigmatism to 20 degrees of eccentricity, while optimizing visual acuity on the axis. These ranges are critically important for enabling predictable correction of peripheral astigmatism for patients with a dioptric power requirement less than a transition point power.The transition point power is the marking power that corresponds to the format factor of a plano-convex lens, which is -1.
[0009] The lens body may comprise a central thickness between 0.62 mm and 1.0 mm. The intraocular lens may additionally comprise an anterior haptic connected to the lens body, and the lens may comprise an arc height between 0.34 mm and 0.65 mm. The lens may comprise a first surface with an anterior surface curvature greater than -0.077 mm-1 and less than 0.00 mm-1 and a second surface with a posterior surface curvature greater than 0.355 mm-1 and less than -0.130 mm-1. Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient.The selection of these parameters also allows the lenses to have a specific format factor. Petition 870250103047, dated 11 / 11 / 2025, page 9 / 75 4 / 53 power that is even more stable within the ranges of the invention, to further assist the lenses' ability to predictably improve peripheral vision.
[0010] The lens may comprise a diopter marking power that is between 18 D and 22 D inclusive. The power format factor may be less than or equal to -1.1 and greater than or equal to -2.0. Advantageously, these marking power and power format factor ranges result in a lens that is optimized so that the lens minimizes off-axis astigmatism while maximizing on-axis visual acuity for lenses with a marking power less than the transition point power. Within these ranges, the lens's power format factor is particularly stable, which is critically important for enabling greater predictability of the lens's structural characteristics that result in optimization. The lens may comprise a center thickness that is between 0.70 mm and 0.90 mm. An anterior haptic may be attached to the lens body, and the lens may comprise an arc height that is between 0.40 mm and 0.60 mm.The lens may comprise a first surface with an anterior surface curvature greater than -0.071 mm-1 and less than -0.00 mm-1 and a posterior surface curvature greater than -0.355 mm-1 and less than -0.134 mm-1. Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient. The respective selection of these parameters additionally allows the lenses to have a power format factor that is even more stable within the optimization ranges, to further assist in the ability of the lenses to predictably minimize peripheral vision while maximizing [missing information]. Petition 870250103047, dated 11 / 11 / 2025, page 10 / 75 5 / 53 visual acuity on the axis.
[0011] The power format factor can be calculated using radii of curvature defined paraxially from the first surface and the second surface.
[0012] The first surface of the lens may comprise a concave surface, and the second surface may comprise a convex surface with respect to the optical axis of the lens. The concave surface may comprise a radius of curvature of the concave surface that is greater than a radius of curvature of the convex surface.
[0013] The power format factor can be calculated according to Potêncin-n^f-Potêncitt post with the formula----------------p—, where Potênciaant is the power of Potênciaant+Potênciapost anterior surface, and Potênciapost is the posterior surface power of the lens body.
[0014] The power format factor can be calculated by ray tracing techniques applied to the intraocular lens. Ray tracing techniques may involve the use of a specific aperture size. Ray tracing techniques may involve using a specific aperture size, a better focus position, and spherical aberration effects on the power format factor.
[0015] A second type of intraocular lens comprises a lens body, wherein the lens body comprises: a refractive index between 1.50 and 1.60 inclusive, a diopter marking power between 20 D and 28 D inclusive, and a power format factor that is less than or equal to -1.0 and greater than or equal to -3. Advantageously, the provision of an intraocular lens according to the marking power range and the power format factor range of the second type allows for the correction of peripheral astigmatism according to a blur parameter less than 1.8 D, while optimizing visual acuity on the axis. Within these ranges, the format factor of Petition 870250103047, dated 11 / 11 / 2025, page 11 / 75 6 / 53 power is stable, meaning that structural features can be selected to produce lenses that are predictably capable of reducing off-axis astigmatism to 20 degrees of eccentricity while optimizing on-axis visual acuity. These ranges are critically important for enabling predictable correction of peripheral astigmatism for patients with a dioptric power requirement lower than a transition point power. Transition point power is the marking power that corresponds to the format factor of a plano-convex lens, which is -1.
[0016] The lens may comprise a central thickness between 0.45 mm and 1.0 mm. The intraocular lens may additionally comprise an anterior haptic connected to the lens body, and the lens may comprise an arc height between 0.30 mm and 0.65 mm. The lens may comprise a first surface with an anterior surface curvature greater than -0.022 mm-1 and less than 0.00 mm-1 and a second surface with a posterior surface curvature greater than 0.170 mm-1 and less than -0.081 mm-1. Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient.The selection of these parameters further allows the lenses to have a power format factor that is even more stable within the ranges of the invention, to further assist the lenses' ability to predictably improve peripheral vision.
[0017] The lens may comprise a diopter marking power that is between 20 D and 27 D. The power format factor may be less than or equal to -1.0 and greater than or equal to -2.4. Advantageously, Petition 870250103047, dated 11 / 11 / 2025, p. 12 / 75 7 / 53 These marking power and power format factor ranges are critically important for obtaining a lens that is optimized to minimize off-axis astigmatism while maximizing on-axis visual acuity. Within these ranges, the lens's power format factor is particularly stable, allowing for greater predictability of the lens's structural characteristics that result in optimization. This allows for optimization of peripheral vision correction for patients with a dioptric power requirement lower than the transition point power. The lens may comprise a center thickness between 0.55 mm and 0.90 mm. An anterior haptic may be attached to the lens body, and the lens may comprise an arc height between 0.35 mm and 0.60 mm.The lens may comprise a first surface with an anterior surface curvature greater than 0.022 mm⁻¹ and less than 0.00 mm⁻¹ and a second surface with a posterior surface curvature greater than -0.170 mm⁻¹ and less than 0.084 mm⁻¹. Advantageously, selecting either of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient. The respective selection of these parameters additionally allows the lenses to have a power format factor that is even more stable within the optimization ranges, to further assist in the lenses' ability to predictably minimize peripheral vision while maximizing visual acuity on the axis.
[0018] The power format factor can be calculated using radii of curvature defined paraxially from the first surface and the second surface.
[0019] The first surface of the lens may comprise a Petition 870250103047, dated 11 / 11 / 2025, page 13 / 75 8 / 53 concave surface, and the second surface may comprise a convex surface with respect to the optical axis of the lens. The concave surface may comprise a radius of curvature on the front of the concave surface that is greater than a radius of curvature on the back of the convex surface.
[0020] The power format factor can be calculated according to Power^^^i-Power^ nost with the formula----------------p—, where Powerant is the power of Potênciaant+Potênciapos is the anterior surface power, and Potênciapos is the posterior surface power of the lens body.
[0021] The power format factor can be calculated by ray tracing techniques applied to the intraocular lens. Ray tracing techniques may involve the use of a specific aperture size. Ray tracing techniques may involve using a specific aperture size, a better focus position, and spherical aberration effects on the power format factor.
[0022] A third embodiment of an intraocular lens comprises a lens body, with the lens body comprising: a refractive index between 1.40 and 1.50 inclusive, a diopter marking power between 23 D and 30 D inclusive, and a power format factor that is less than or equal to -0.2 and greater than or equal to -1. Advantageously, the provision of an intraocular lens according to the marking power range and the power format factor range of the third embodiment allows for the correction of peripheral astigmatism according to a blur parameter less than 1.8 D, while optimizing visual acuity on the axis. Within these ranges, the power format factor is stable, meaning that structural features can be selected in order to produce lenses that are predictably capable of producing the effect of reducing off-axis astigmatism to 20 degrees of eccentricity, while optimizing visual acuity on the axis.The bands of the third embodiment of the invention are of critical importance to enable... Petition 870250103047, dated 11 / 11 / 2025, page 14 / 75 9 / 53 correction of peripheral astigmatism for patients with a dioptric power requirement greater than a transition point power. The transition point power is the marking power that corresponds to the format factor of a plano-convex lens, which is -1.
[0023] The lens may comprise a central thickness between 0.62 mm and 1.0 mm. An anterior haptic may be connected to the lens body, and the lens may comprise an arc height between 0.34 mm and 0.65 mm. The lens may comprise a first surface with an anterior surface curvature greater than 0 mm⁻¹ and less than 0.120 mm⁻¹ and a second surface with a posterior surface curvature greater than -0.367 mm⁻¹ and less than -0.130 mm⁻¹. Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient.The selection of these parameters further allows the lenses to have a power format factor that is even more stable within the ranges of the invention, to further assist the lenses' ability to predictably improve peripheral vision.
[0024] The lens may comprise a diopter marking power that is between 24 D and 29 D inclusive. The power format factor is less than or equal to -0.3 and greater than or equal to -0.8. Advantageously, these marking power and power format factor ranges are critically important in resulting in a lens that is optimized so that the lens minimizes off-axis astigmatism while maximizing on-axis visual acuity. Within these ranges, the lens's power format factor is particularly stable, allowing for a greater ability to predict the structural characteristics of the lens that Petition 870250103047, dated 11 / 11 / 2025, p. 15 / 75 10 / 53 results in optimization for patients with a dioptric power requirement greater than the transition point power. The lens may comprise a center thickness between 0.70 mm and 0.90 mm. An anterior haptic may be connected to the lens body, and the lens may comprise an arc height between 0.40 mm and 0.60 mm. The lens may comprise a first surface with an anterior surface curvature greater than 0 mm⁻¹ and less than 0.12 mm⁻¹ and a second surface with a posterior surface curvature greater than 0.36 mm⁻¹ and less than -0.13 mm⁻¹. Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient.The selection of these parameters further allows the lenses to have a power format factor that is even more stable within the minimization ranges, to further assist the lenses' ability to predictably minimize peripheral vision while maximizing visual acuity along the axis.
[0025] The power format factor can be calculated using radii of curvature defined paraxially from the first surface and the second surface.
[0026] The power format factor can be calculated according to Potêncin-n^f—Potêncitt post with the formula----------------p—, where Potênciaant is the power of Potênciaant+Potência.post anterior surface, and Potênciapost is the posterior surface power of the lens body.
[0027] The power format factor can be calculated by ray tracing techniques applied to the intraocular lens. Ray tracing techniques may involve the use of a specific aperture size. Ray tracing techniques may involve using Petition 870250103047, dated 11 / 11 / 2025, page 16 / 75 11 / 53 a specific aperture size, a better focus position, and spherical aberration effects in the power format factor.
[0028] A fourth embodiment of an intraocular lens comprises a lens body, with the lens body comprising: a refractive index between 1.50 and 1.60 inclusive, a diopter marking power between 23 D and 35 D inclusive, and a power format factor that is less than or equal to -0.2 and greater than or equal to -1. Advantageously, the provision of an intraocular lens according to the marking power range and the power format factor range of the first embodiment allows for the correction of peripheral astigmatism according to a blur parameter less than 1.8 D, while optimizing visual acuity on the axis. Within these ranges, the power format factor is stable, meaning that structural features can be selected in order to produce lenses that are predictably capable of producing the effect of reducing off-axis astigmatism to 20 degrees of eccentricity, while optimizing visual acuity on the axis.The bands of the fourth embodiment of the invention are of critical importance in enabling the correction of peripheral astigmatism for patients with a dioptric power requirement greater than a transition point power. The transition point power is the marking power that corresponds to the format factor of a plano-convex lens, which is -1.
[0029] The lens may comprise a center thickness between 0.45 mm and 1.0 mm. An anterior haptic may be attached to the lens body, and the lens may comprise an arc height between 0.30 mm and 0.65 mm. The lens may comprise a first surface with an anterior surface curvature greater than 0.00 mm-1 and less than 0.082 mm-1 and a second surface with a posterior surface curvature greater than -0.179 mm-1 and less than -0.081 mm-1. Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lenses. Petition 870250103047, dated 11 / 11 / 2025, page 17 / 75 12 / 53 allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being excessively closed and thus reduce discomfort when inserted into a patient. The respective selection of these parameters further allows the lenses to have a power format factor that is even more stable within the ranges of the invention, to further assist the lenses' ability to predictably improve peripheral vision.
[0030] The intraocular lens may have a diopter marking power between 25 D and 35 D inclusive. The power format factor may be less than or equal to -0.40 and greater than or equal to -0.95. Advantageously, these marking power and power format factor ranges are critically important in resulting in a lens that is optimized so that the lens minimizes off-axis astigmatism while maximizing on-axis visual acuity. Within these ranges, the lens's power format factor is particularly stable, allowing for greater predictability of the lens's structural characteristics that result in optimization for patients with a dioptric power requirement greater than the transition point power. The lens may comprise a center thickness that is between 0.55 mm and 0.90 mm. An anterior haptic may be attached to the lens body, and the lens may comprise an arc height that is between 0.35 mm and 0.60 mm.The lens may comprise a first surface with an anterior surface curvature greater than 0.01 mm⁻¹ and less than 0.082 mm⁻¹ and a second surface with a posterior surface curvature greater than 0.179 mm⁻¹ and less than -0.081 mm⁻¹. Advantageously, selecting either of these parameters to be within their respective ranges increases the adaptability of the lenses, allowing the lenses to be implanted with industrially available inserters. These ranges for each parameter also prevent the lenses from being... Petition 870250103047, dated 11 / 11 / 2025, page 18 / 75 13 / 53 lenses are excessively closed, thus reducing discomfort when inserted into a patient. The respective selection of these parameters additionally allows the lenses to have a power format factor that is even more stable within the optimization ranges, to further assist in the lenses' ability to predictably minimize peripheral vision while maximizing visual acuity on the axis.
[0031] The power format factor can be calculated using radii of curvature defined paraxially from the first surface and the second surface.
[0032] The power format factor can be calculated according to Power^^^i-Power^ nost with the formula----------------p—, where Powerant is the power of Potênciaant+Potênciapos is the anterior surface power, and Potênciapos is the posterior surface power of the lens body.
[0033] The power format factor can be calculated by ray tracing techniques applied to the intraocular lens. Ray tracing techniques may involve the use of a specific aperture size. Ray tracing techniques may involve using a specific aperture size, a better focus position, and spherical aberration effects on the power format factor.
[0034] The invention also provides a set of intraocular lenses that improve peripheral vision; the set comprising: at least one lens according to the first and / or second modality; and at least one lens according to the third and / or fourth modality. The provision of a lens set allows for the correction of peripheral vision for prescriptions requiring a dioptric power lower than a transition point power, as well as the correction of peripheral vision for prescriptions with a dioptric power higher than a transition point power. The transition point power may be a marking power corresponding to a format factor of -1. The lens set of Petition 870250103047, dated 11 / 11 / 2025, p. 19 / 75 14 / 53 invention therefore allows for the correction of peripheral vision across the entire range of possible prescriptions and the adaptation of the supplied lens based on the prescription.
[0035] At least one lens may comprise a series of lenses, wherein the diopter marking power of each lens in the lens series differs by at least 0.25 D. Advantageously, the set may provide a range of lenses that may be selected by a user to adapt the selected lenses to the patient's dioptric power requirements for those below the transition point power and for those above the transition point power.
[0036] The invention also provides a method for designing a set of intraocular lenses for enhanced peripheral vision, wherein, as the lens marking power increases from 17 D to 30 D, the power format factor increases from -2.5 to -0.2, the method comprising:
[0037] for each dialing power increment of at least 0.25 D, to provide an intraocular lens with an optical power that reduces optical errors in an image produced in a peripheral retinal location of a patient's eye positioned at a distance from the fovea,
[0038] wherein, for labeling powers with a format factor less than or equal to -1, the intraocular lens comprises a lens body formed in accordance with the first modality and / or the second modality,
[0039] wherein, for marking powers with a format factor greater than or equal to -1, the intraocular lens comprises a lens body formed according to the third modality and / or the fourth modality,
[0040] wherein the defocus parameter of each intraocular lens is less than 1.8 diopters, and the defocus parameter is calculated according to: Defocus parameter = jSphere2 + Cylinder2. The supply of a set of lenses designed according to the Petition 870250103047, dated 11 / 11 / 2025, p. 20 / 75 15 / 53 The method of the invention allows for the correction of peripheral vision for prescriptions requiring a dioptric power lower than a transition point power, as well as the correction of peripheral vision for prescriptions with a dioptric power higher than a transition point power. The transition point power is a marking power corresponding to a format factor of -1. The lens set of the invention therefore allows for the correction of peripheral vision across the entire range of possible prescriptions and the adaptation of the supplied lens based on the prescription. BRIEF DESCRIPTION OF THE DRAWINGS
[0041] Figure 1 illustrates an example of the prior technique of using an intraocular lens with a concave anterior surface and a convex posterior surface to adjust the focal length of peripheral images focusing on the retina of an eye.
[0042] Figure 2 is an illustration of an intraocular lens according to some embodiments of this invention.
[0043] Figure 3 is a graphical representation and corresponding formulas for calculating surface power values from the respective refractive indices and radii of curvature according to the embodiments of this invention.
[0044] Figure 4 is a graphical representation of peripheral vision lenses with a refractive index of 1.471.
[0045] Figure 5 is a graphical representation of peripheral vision lenses with a refractive index of 1.55.
[0046] Figure 6 is a graphical representation of a region of format factors and marking powers in which lenses with a refractive index of 1.471 have been optimized according to the discussion in the present invention.
[0047] Figure 7 is a graphical representation of a region of format factors and marking powers in which lenses with a Petition 870250103047, dated 11 / 11 / 2025, page 21 / 75 16 / 53 refractive index of 1.55 were optimized according to the discussion in the present invention. DETAILED DESCRIPTION
[0048] This invention considers multiple types of ophthalmic lenses used to correct vision and presents reliable solutions to problems involved when an intraocular lens must be implanted in a patient and provides reliable positioning for structural features of intraocular lenses of different marking powers.
[0049] The embodiments of this invention incorporate the common meaning of the terms of the art in the field of intraocular lenses. For example, as shown in Figure 2, this invention relates to haptics 320 attached to a lens body that are fitted to hold the intraocular lens 300 in place in a patient's eye. The haptics 320 establish an anterior haptic plane 325 which is a useful reference point for comparative purposes of different lenses. An anterior haptic plane 325 is defined by a plane that is normal to the optical axis and extends through the most anterior surface of the uncompressed intraocular lens haptics 320. As shown in Figure 2, an arc height 350 of an intraocular lens is the distance between the anterior haptic plane 325 and a plane normal to the optical axis containing an anterior surface 330 of the intraocular lens body, calculated as defined in ISO 11979-1.Figure 2 also shows a measurement of a central thickness 310, which is the difference between the sagittal thickness and the arc height, as defined by ISO 11979-1. The intraocular lens body in Figure 2 has an anterior surface 330, a posterior surface 340, a frontal principal plane determined, at least in part, by the optical effects of the anterior surface of the intraocular lens 300, and a posterior principal plane determined, at least in part, by the optical effects of the posterior surface of the intraocular lens 300. This invention calculates the best possible structure for a given marking power. Petition 870250103047, dated 11 / 11 / 2025, p. 22 / 75 17 / 53 measured in diopters. As used herein, marking power refers to dioptric power as defined in ISO 11979-1, which can be calculated using ray tracing techniques. The central thickness 310, anterior surface curvature, and posterior surface curvature are used according to standards in the intraocular lens technique. Standard materials for forming intraocular lenses are within the scope of this invention. In various implementations, the optics may comprise materials such as acrylic, silicone, polymethyl methacrylate (PMMA), styrene-ethylene-butylene-styrene (C-FLEX) block copolymers or other styrene-based copolymers, polyvinyl alcohol (PVA), polystyrenes, polyurethanes, hydrogels, etc.
[0050] This invention uses power format factor values for intraocular lenses (IOLs) to identify structural features of intraocular lenses necessary to achieve different marking powers measured in diopters (D) that are suitable after implantation in patients. By managing and manipulating at least the structural features disclosed herein and shown in Figure 2 and equations 1 to 10 below, the intraocular lenses of this invention perform extremely well in treating eye diseases and maintaining focus and clarity for both foveal and peripheral vision for a patient receiving an implanted intraocular lens.
[0051] As an initial introduction, this invention uses at least two different intraocular lens structures that are configured as peripheral vision correction intraocular lenses as non-limiting examples that show the characteristics and benefits of the work disclosed herein. Figure 2 illustrates a lens in which the concave surface faces the object to be photographed and / or the light source of the image. An intraocular lens may have convex surfaces on the anterior and posterior sides of the intraocular lens. Plano-convex intraocular lenses Petition 870250103047, dated 11 / 11 / 2025, p. 23 / 75 18 / 53 have an anterior surface that is flat or substantially flat and a convex posterior surface.
[0052] The power format factor varies for different lens types, but it can also be constant for a lens with a flat surface. For example, a constant power format factor is equal to minus one (-1) for a plano-convex lens. In non-limiting embodiments, intraocular lenses with power format factors that are less than or equal to minus one (-1) are provided, and intraocular lenses with power format factors that are greater than or equal to minus one (-1) are also provided. An intraocular lens with a power format factor greater than or equal to minus one may have a lens body that is formed differently from the lens body of an intraocular lens with a power format factor less than or equal to minus one.Without limiting this invention to any specific power format factors or marker powers, the lenses of this invention may have a marker power range of about 17D to 35D to illustrate various embodiments. At a constant power format factor of a plano-convex lens (e.g., minus 1), the lens shape transitions from that of a lens with a power format factor less than or equal to minus one to that of a lens with a power format factor greater than or equal to minus one. At lower marker power ranges, including but not limited to a range of 7D to 17D, the anterior and posterior surfaces of the intraocular lens do not necessarily exhibit power responses that would be expected from simple surfaces with consistent curvature across the anterior and posterior surfaces.Instead, the anterior and posterior surfaces of the intraocular lens may effectively include complex surfaces that vary across their respective surfaces. The variance between the surfaces may be in terms of variations in surface curvature (i.e., exhibiting structures of...). Petition 870250103047, dated 11 / 11 / 2025, page 24 / 75 19 / 53 toroidal surface or Zernike surfaces) and may require further investigation to ensure that a desired and reliable response is provided after intraocular lens implantation in a patient.
[0053] The power format factor of an intraocular lens is calculated according to the formula: Power before - Power after Powerant + Powerpost (Equation 1), where Powerant is the anterior surface power, and Powerpost is the posterior surface power of the lens body.
[0054] The previous surface power is calculated according to: Power^ =n'0L~n^“O(Eq. 2)Rant
[0055] The power of the posterior surface is calculated according to: n_L^ _.nmeio -nIOL Power = ------------ (Eq. 3) ^ Rpost Let Rant be the anterior radius of curvature, and Rpost is the posterior radius of curvature of the lens body. A first surface of an intraocular lens defines the anterior radius of curvature Rant, and a second surface defines the posterior radius of curvature Rpost. n-medium is the refractive index of the intraocular lens, while n-medium is the refractive index of the medium in which the intraocular lens is implanted. For power in diopters, radii must be given in millimeters.
[0056] The radius format factor for an intraocular lens is calculated according to the formula (Rp°st-R αη) (Eq.4). Rpost+Rant, where the ray format factor uses the general marking radius of curvature for each lens, the power format factor can be calculated by ray tracing techniques applied to the intraocular lens. In some non-limiting modalities, ray tracing techniques may include the use of a specific aperture size. Ray tracing techniques may also involve using a specific aperture size, a better focus position, and spherical aberration effects in the Petition 870250103047, dated 11 / 11 / 2025, page 25 / 75 20 / 53 power format factor. The power format factor and the radius format factor may be equal for ideally simple surfaces of known curvature, but the values are not always the same, indicating more complicated surface curvatures.
[0057] The lensmaker's formula illustrates how the focal length of an intraocular lens is affected by the radius of curvature of the anterior and posterior surfaces, where F is the focal length, ni_io is the refractive index of the lens, Ri is the radius of curvature of the first surface, and R2 is the radius of curvature of the second surface: 1 = (nI0L - 1)(-1 - 1-) (Equation 5) r «1 «2
[0058] Prior technique efforts, such as the 100 intraocular lens shown in Figure 1, focused on the lensmaker's equation to adjust radius values and focal lengths for intraocular lenses without in-depth analysis of the variable power responses that anterior and posterior surfaces may exhibit after implantation.
[0059] The measurements given throughout this application are discussed in relation to the Liou and Brennan ocular model (Liou HL, Brennan NA. Anatomically accurate, finite model eye for optical modeling. J Opt Soc Am A Opt Image Sci Vis. August 1997;14(8):1684 to 1695. doi: 10.1364 / josaa.14.001684. PMID: 9248060). For the lenses of this invention, the arc height ranges are chosen between 0.34 mm and 0.65 mm. The lenses may comprise arc heights in the range of 0.40 mm to 0.60 mm or 0.50 mm to 0.55 mm. The arc height may be 0.65 mm. The center thickness is chosen in the range of 0.62 mm to 1.0007 mm. The center thickness can vary from 0.70 mm to 0.90 mm or from 0.80 mm to 0.85 mm. The format factor can range from -4 to 0. These parameter ranges are selected to provide lenses that can be implanted with industrially available inserters, as well as to avoid producing lenses that are excessively closed, thus avoiding the production of lenses that are too closed. Petition 870250103047, dated 11 / 11 / 2025, p. 26 / 75 21 / 53 mode, to reduce discomfort in a patient. For these reasons, lenses with a posterior radius smaller than -4 mm are also excluded from this invention. In this invention, the length of the eye is fixed by the paraxial focus of an equivalent ZCB00 lens (Tecnis® monofocal) with a 2D power below the marking power of the intraocular lens (i.e., an intraocular lens with a marking power of 22D uses the length of the eye corresponding to a ZCB00 20D lens).
[0060] An implanted intraocular lens can be classified as a peripheral vision correcting lens if, for the implanted intraocular lens, the off-axis astigmatism measured at 20 degrees of eccentricity from the optical axis through the iris is less than or equal to a threshold value of 1.8 D. Eccentricity refers to the angular distance from the center of the visual field, such as the fovea centralis. Off-axis astigmatism at 20 degrees can be calculated according to a peripheral blur parameter of an intraocular lens, as measured at that angle. For example, for an intraocular lens with a 20 D marking power that corrects peripheral vision, the peripheral astigmatism might be 1.3 D or 1.7 D at 20 degrees of eccentricity.
[0061] The vectors Jo and J45, as well as the sphere, cylinder, and blur parameters, can be calculated. These values are calculated according to the following equations, in which C(i, j) are corresponding Zernike coefficients in pm, er is the pupil radius in mm. For these formulas, a negative sign convention is used for the cylinder definition, and the retinal curvature is defined according to Atchinson et al. (Optical models for human myopic eyes, 2006). 2V6 · C(2, 2) ^2 (Eq. 6) 2^6·E(2, -2) ^2 (Eq. 7) Sphere = - 4^2, 0)(Eq. 8) Petition 870250103047, dated 11 / 11 / 2025, page 27 / 75 22 / 53 Cylinder = -2 · V / 02+ J452 (Eq. 9) Blur parameter = jSphere2 + Cylinder2 (Eq. 10)
[0062] With reference to Figures 4 and 5, this invention provides ranges that are of critical importance for lenses with marking powers that correct peripheral vision according to the blur parameter condition, have an absolute value below 1.8 D for peripheral cylinder at 20 degrees of eccentricity, and optimize on-axis visual acuity and contrast sensitivity. On-axis visual acuity and contrast sensitivity are optimized for selected values of arc height, center thickness, and format factor within the ranges discussed in the present invention. For the selected values, on-axis visual acuity and contrast sensitivity are optimized by adjusting the anterior and / or posterior aspheric parameters to produce a lens with on-axis performance that is as close as possible to diffraction-limited performance for a 5.65 mm on-axis entrance pupil in green light (550 nm).Graph 400 in Figure 4 shows peripheral vision lenses with a refractive index of 1.471 that correct peripheral vision according to the blur parameter condition, have an absolute value below 1.8 D for the peripheral cylinder at 20 degrees of eccentricity, and optimize visual acuity on the axis and contrast sensitivity, while graph 500 in Figure 5 shows peripheral vision lenses with a refractive index of 1.55 that correct peripheral vision according to the blur parameter condition, have an absolute value below 1.8 D for the peripheral cylinder at 20 degrees of eccentricity, and optimize visual acuity on the axis. Both Figure 4 and Figure 5 show, respectively, plots of the format factor against the marking power for lenses that satisfy the conditions. In both plots, the lenses are restricted by having an arc height between 0.34 mm and 0.65 mm and a center thickness in the range of 0.62 mm to 1.0007 mm. Petition 870250103047, dated 11 / 11 / 2025, page 28 / 75 23 / 53
[0063] With reference to graphs 600 and 700 of Figures 6 and 7, respectively, this invention also provides sub-ranges corresponding to optimal marking powers and power format factors that are of critical importance for a peripheral vision lens that maximizes off-axis astigmatism reduction at 20 degrees of eccentricity while maximizing on-axis visual acuity and contrast sensitivity. Figure 6 shows the optimal region for a refractive index of 1.471 as shaded regions 610 and 620. Figure 7 shows the optimal region for a refractive index of 1.55 as shaded regions 710 and 720. In both graphs, the lenses are constrained by having an arc height between 0.34 mm and 0.65 mm and a center thickness in the range of 0.62 mm to 1.0007 mm.
[0064] To calculate these sub-bands corresponding to regions 610, For 620, 710, and 720, an optimization of a modulation transfer function (MTF) was performed. Contrast sensitivity is known to be proportional to the Modulation Transfer Function (MTF); thus, sufficient on-axis visual acuity and / or contrast sensitivity can be achieved through MTF optimization. Optimization can be performed at one or more spatial frequencies or using a figure of merit proportional to the MTF levels at one or more spatial frequencies. In a non-limiting example, sufficient contrast sensitivity is achieved if the MTF is at least 0.7 for a 5 mm pupil in green light at a spatial frequency of 50 cycles / mm, as measured in eye model #2 according to ISO 11979-2 2014.The following parameters and their associated weighting for MTF optimization are as follows: a lens that is diffraction-limited on-axis for a large entrance pupil of 5.65 mm (weight = 1); reduce each of off-axis astigmatism and off-axis defocus by 20 degrees for an entrance pupil of 4 mm (weight = 0.01 each); increase. Petition 870250103047, dated 11 / 11 / 2025, p. 29 / 75 24 / 53 MTF values are 20 degrees off-axis for each of the sagittal and tangential foci at a spatial frequency of 25 cycles per mm for a 4 mm entrance pupil (weight = 0.02 each); MTF values are 20 degrees off-axis for sagittal and tangential foci at a spatial frequency of 25 cycles per mm for a 4 mm entrance pupil that are as similar as possible (weight = 0.01). MTF was calculated using monochromatic green light at 550 nm, with the anterior haptic plane of the lens approximately 0.5 mm behind the iris in a Liou and Brennan eye model and with retinal curvature defined according to Atchinson et al. (Optical Models for Human Miotic Eyes, 2006).This optimization can be used to determine how lens parameters, such as arc height, center thickness, anterior surface curvature, posterior surface curvature, and shape factor, can be adapted (according to the lensmaker's equation) to achieve desirable sub-ranges of marking powers that are optimal for improving a patient's peripheral vision. The sub-ranges were then selected according to the region over which the observed optimization is most stable, so that the optimization effect can be predictable given the appropriate selections of structural features.
[0065] Figure 3 presents an example of intraocular lens characteristics taking into account the respective refractive indices for the media before the lens (n1), the lens material (n2), and the media after the lens (n3). With known radius curvatures (R1, R2) for the anterior lens surface and the posterior lens surface, the surface powers (i.e., AnteriorPower and PosteriorPower) of the lens can be calculated according to equations 2 and 3 given above. For AnteriorPower, nmedium corresponds to n-, while for PosteriorPower, nmedium corresponds to n2. This invention includes surface curvature values in numerous diopter marking powers for the anterior and posterior surfaces of numerous different lenses with respective Petition 870250103047, dated 11 / 11 / 2025, p. 30 / 75 25 / 53 refractive indices. This invention considers an intraocular lens with a power format factor less than or equal to negative one and / or an intraocular lens with a power format factor greater than or equal to negative one. The lens body of the intraocular lens with a power format factor less than or equal to negative one may be differentially formed from the lens body of the intraocular lens with a power format factor greater than or equal to negative one. The invention may provide a lens assembly comprising at least one first lens with a power format factor less than or equal to negative one. Additionally or alternatively, the lens assembly may comprise at least one second lens with a power format factor greater than or equal to negative one.A lens with a power format factor less than or equal to negative one and / or a lens with a power format factor greater than or equal to negative one may have a refractive index (n2) between 1.40 and 1.50 and / or a refractive index (n2) between 1.50 and 1.60. Other refractive index ranges are considered. The refractive index may be between 1.45 and 1.48. The refractive index may be between 1.54 and 1.56. The refractive index may be 1.471. The refractive index may be 1.55. The respective power format factors and radius of curvature for different refractive indices coincide with the standards established for the lenses discussed above. Indeed, the differences and similarities between the power format factors for the lenses discussed above indicate patterns that are useful for predicting the effects of lens characteristics, such as, but not limited to, arc height, as discussed above.These same effects can be shown in additional tests for lenses with varying refractive index values as revealed here.
[0066] This invention establishes structural factors for intraocular lenses that have shown exceptional results for foveal vision and peripheral vision after implantation according to the optimization discussed. Petition 870250103047, dated 11 / 11 / 2025, page 31 / 75 26 / 53 in the present invention. Lenses with a power format factor less than or equal to minus one
[0067] As mentioned above and as demonstrated in Figures 4 to 7 show that certain lower marking powers, for example, marking powers for a lens with a power format factor less than or equal to negative one, exhibit power format factor values that are less stable in this lower marking power range. The lower marking power range can be from 7 D to 17 D. As further shown by Figures 4 to 7, similar uncertainty is seen at higher marking powers above 28 D and below 36 D for a lens with a power format factor less than or equal to negative one. This provides a basis for fine-tuning the anterior surface curvature and posterior surface curvature of each lens at each marking power.Due to the selection of central thickness, arc height, and format factor within the ranges described in this invention, the anterior surface curvature and posterior surface curvature can be adjusted to produce peripheral vision lenses with stable power response over a range of marking powers. As demonstrated by graph 400 of Figure 4, the range in which the power response is stable for an intraocular lens with a power format factor less than or equal to minus one and a refractive index between 1.40 and 1.50 is from 17 D to 23 D. With reference to graph 500 of Figure 5, for an intraocular lens with a power format factor less than or equal to minus one and a refractive index between 1.50 and 1.60, the stable range of marking powers is between 20 D and 28 D.Lenses with these marking bands have a readily predictable ability to optimize visual acuity along the axis to be as close as possible to the diffraction-limited performance limit, while correcting peripheral vision. Petition 870250103047, dated 11 / 11 / 2025, p. 32 / 75 27 / 53
[0068] One embodiment of a peripheral vision intraocular lens comprises a lens body. The lens body has a diopter labeling power between 17 D and 23 D and a refractive index value between about 1.40 and 1.50. For these labeling powers and refractive indices, the power format factor is between -1 and -2.5. The first surface may have an anterior surface curvature between -0.77 mm⁻¹ and 0.00 mm⁻¹. The second surface may have a posterior surface curvature between -0.355 mm⁻¹ and -0.130 mm⁻¹. The central thickness may be between 0.62 mm and 1.0 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.34 mm and 0.65 mm.
[0069] For a lens body modality with a refractive index between approximately 1.50 and 1.60 and diopter marking powers between 20 D and 28 D, the power format factor is between -1 and -3. The first surface may have an anterior surface curvature between -0.022 mm-1 and 0.00 mm-1. The second surface may have a posterior surface curvature between -0.170 mm-1 and -0.081 mm-1. The central thickness may be between 0.45 mm and 1.0 mm. An anterior haptic may be attached to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.30 mm and 0.65 mm.
[0070] An intraocular lens comprising a lens body made according to the following sub-ranges of marking power and power format factor can be provided. The marking power sub-range can be between 18 D and 22 D for a lens with a refractive index between about 1.40 and 1.50 and between 20 D and 27 D for a lens with a refractive index between 1.50 and 1.60. With reference to the optimization function of Figures 6 and 7, the narrow bands 610 and 710 of the optimization function within these sub-ranges demonstrate that lenses made with marking powers within the sub-ranges have an even more stable format factor in this range, compared with the wider ranges. Petition 870250103047, dated 11 / 11 / 2025, page 33 / 75 28 / 53 wide discussed above. This stability means that it is easier to predict which structural features will result in lenses that are able to maximize visual acuity on the axis while minimizing off-axis astigmatism at 20 degrees of eccentricity according to the optimization MTF described in this application.
[0071] In one embodiment, the lens has a diopter marking power between 18 D and 22 D and refractive index values between approximately 1.40 and 1.50. The lens has a power format factor between -1.1 and 2.0. In this case, the first surface may have an anterior surface curvature, or between -0.071 mm-1 and -0.00 mm-1. The second surface may have a posterior surface curvature between -0.355 mm-1 and -0.134 mm-1. The central thickness for the lens may be between 0.70 mm and 0.90 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.40 mm and 0.60 mm.
[0072] An additional embodiment of a lens has a diopter marking power between 20 D and 27 D and a refractive index between approximately 1.50 and 1.60. In this case, the lens has a power format factor between -1.0 and -2.4. The first surface may have an anterior surface curvature between -0.022 mm-1 and -0.00 mm-1. The second surface may have a posterior surface curvature between -0.170 mm-1 and -0.084 mm-1. The central thickness may be between 0.55 mm and 0.90 mm. An anterior haptic may be attached to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.35 mm and 0.60 mm. Lenses with a power format factor greater than or equal to minus one.
[0073] As discussed above, for an intraocular lens with a marking power greater than a transition point power, the intraocular lens includes a lens body that can be formed Petition 870250103047, dated 11 / 11 / 2025, p. 34 / 75 29 / 53 differentially from the lens body for an intraocular lens with a marking power lower than a transition point power. The transition point power may be a marking power corresponding to an intraocular lens with a format factor of -1. For example, with reference to Figure 4, the transition point power may be 23 D, 24 D, or 25 D for a lens with a refractive index between 1.40 and 1.50. With reference to Figure 5, for a lens with a refractive index between 1.50 and 1.60, the transition point power may be 23 D, 25 D, or 28 D. Other transition point powers may be chosen as appropriate.
[0074] For higher marking powers for lenses with a power format factor greater than or equal to negative one, the rate of increase of power format factors in these marking power ranges diverges, but to a lesser extent than discussed previously for marking powers lower than the transition point power. With reference to Figure 4, between certain increasing marking powers, the rate of increase of power format factors in this marking power range exhibits little variation. These marking power ranges may be between 23 D and 30 D for a lens with a power format factor greater than or equal to negative one and a refractive index between 1.40 and 1.50, or between 23 D and 35 D for a lens with a power format factor greater than or equal to negative one and a refractive index between 1.50 and 1.60.Within these ranges, the anterior surface curvature and posterior surface curvature can be refined to produce readily predictable variation in the shape factor across the entire range. This stability increases the ability to predict the structural characteristics that allow lenses to correct peripheral vision while optimizing visual acuity along the axis.
[0075] One lens modality has a diopter marking power between 23 D and 30 D and refractive index values between approximately Petition 870250103047, dated 11 / 11 / 2025, p. 35 / 75 30 / 53 1.40 and 1.50. The power format factor is between -0.2 and -1. For these ranges, the first surface can have an anterior surface curvature between 0 mm⁻¹ and 0.120 mm⁻¹. The second surface can have a posterior surface curvature between -0.367 mm⁻¹ and -0.130 mm⁻¹. The central thickness can be between 0.62 mm and 1.0 mm. An anterior haptic can be connected to the lens body to hold the lens in place after implantation, and the intraocular lens can exhibit an arc height between 0.34 mm and 0.65 mm.
[0076] One embodiment of a lens with a refractive index between approximately 1.50 and 1.60 has diopter marking powers between 23 D and 35 D. The power format factor is between -0.2 and -1. In this case, the first surface may have an anterior surface curvature between 0.00 mm⁻¹ and 0.082 mm⁻¹. The second surface may have a posterior surface curvature between -0.179 mm⁻¹ and -0.081 mm⁻¹. The central thickness may be between 0.45 mm and 1.0 mm. An anterior haptic may be attached to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.30 mm and 0.65 mm.
[0077] Within at least one example subrange, such as between D and 29 D for a lens with a power format factor greater than or equal to minus one with a refractive index between 1.40 and 1.50, as shown in area 620 of Figure 6, or between 25 D and 35 D for a lens with a refractive index between 1.50 and 1.60, as shown in area 720 of Figure 7, the rate of increase of the power format factors is determined so that the differences are statistically insignificant and the power format factor appears to exhibit even greater stability. These subranges can be selected in order to optimize the structural characteristics of the intraocular lens to result in minimized off-axis astigmatism at 20 degrees of eccentricity and maximized on-axis visual acuity, thus improving vision. Petition 870250103047, dated 11 / 11 / 2025, page 36 / 75 31 / 53 peripheral. An intraocular lens comprising a lens body, made in accordance with the following sub-ranges of marking power and power format factor, can be provided in order to maximize visual acuity on the axis while minimizing off-axis astigmatism at 20 degrees of eccentricity according to the optimization disclosed herein.
[0078] An additional embodiment of a lens has a diopter marking power between 24 D and 29 D, a refractive index between approximately 1.40 and 1.50, and a power format factor between -0.3 and -0.8. In this case, the first surface may have an anterior surface curvature between 0 mm⁻¹ and 0.12 mm⁻¹. The second surface may have a posterior surface curvature between 0.36 mm⁻¹ and 0.13 mm⁻¹. The central thickness for the lens may be between 0.70 mm and 0.90 mm. An anterior haptic may be attached to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.40 mm and 0.60 mm.
[0079] A lens modality with a diopter marking power between 25 D and 35 D and refractive index values between approximately 1.50 and 1.60 has a power format factor between -0.7 and -0.95. In this case, the first surface may have an anterior surface curvature between 0.01 mm-1 and 0.082 mm-1. The second surface may have a posterior surface curvature between -0.179 mm-1 and -0.081 mm-1. The central thickness for the lens may be between 0.55 mm and 0.90 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.35 mm and 0.60 mm. lens set
[0080] A lens set may be supplied, wherein the lens set comprises at least one lens with a power format factor less than or equal to minus one as defined above and / or at least one lens with a power format factor Petition 870250103047, dated 11 / 11 / 2025, p. 37 / 75 32 / 53 greater than or equal to minus one as defined above. The lens set may comprise a series of lenses. The diopter marking power of each lens in the lens series may vary by at least 0.25 D compared to the other lenses in the lens series. For example, the lens series may comprise 5 lenses with diopter marking powers of 17.5 D, 17.75 D, 18 D, 18.25 D, 18.5 D. The diopter marking power of each lens in the lens series may vary by 0.5 D, 1 D, 2 D, 3 D, 4 D, or 5 D compared to the other lenses in the lens series. The lenses in the lens set may have a marking power below a transition point power or a marking power above a transition point power.The intraocular lens body with a marking power above the transition point power can be differentially shaped from the intraocular lens body with a marking power below the transition point power. The transition point power is a marking power that corresponds to an intraocular lens with a format factor of -1. For example, with reference to Figure 4, the transition point power can be 23 D, 24 D, or 25 D for a lens with a refractive index between 1.40 and 1.50. With reference to Figure 5, for a lens with a refractive index between 1.50 and 1.60, the transition point power can be 23 D, 25 D, or 28 D. Other transition point powers can be chosen as appropriate.
[0081] The provision of a lens set allows for the correction of peripheral vision for prescriptions requiring a dioptric power lower than a transition point power, as well as the correction of peripheral vision for prescriptions with a dioptric power higher than a transition point power. The embodiments of the lens set of the invention therefore allow for the correction of peripheral vision across the entire range of possible prescriptions. Advantageously, the set can provide a range of lenses that can be selected by a user for Petition 870250103047, dated 11 / 11 / 2025, p. 38 / 75 33 / 53 to adapt the selected lenses to the patient's dioptric power requirements.
[0082] According to areas 610 and 620 in Figure 6, an embodiment of a lens set with a refractive index between 1.40 and 1.50 comprises at least one first lens with a diopter marking power between 17 diopters and 23 diopters with a power format factor that is less than or equal to -1.0 and greater than or equal to -2.5, and at least one second lens with a diopter marking power between 23 diopters and 30 diopters and with a power format factor that is less than or equal to -0.2 and greater than or equal to -1. Within these ranges, the anterior surface curvature and the posterior surface curvature can be refined to produce readily predictable variation in the format factor throughout the range. This stability increases the ease with which the lenses are able to correct peripheral vision while optimizing visual acuity on the axis.
[0083] For at least one first lens, the first surface may have an anterior surface curvature between -0.77 mm-1 and 0.00 mm-1. The second surface may have a posterior surface curvature between 0.355 mm-1 and -0.130 mm-1. The central thickness may be between 0.62 mm and 1.0 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.34 mm and 0.65 mm.
[0084] For at least one second lens in the lens assembly, the first surface may have an anterior surface curvature between 0 mm⁻¹ and 0.120 mm⁻¹. The second surface may have a posterior surface curvature between -0.367 mm⁻¹ and -0.130 mm⁻¹. The center thickness may be between 0.62 mm and 1.0 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.34 mm and 0.65 mm.
[0085] According to areas 710 and 720 in Figure 7, a second Petition 870250103047, dated 11 / 11 / 2025, page 39 / 75 The 34 / 53 modality of a lens set comprises lenses with a refractive index between 1.50 and 1.60. The lens set comprises at least one first lens with a diopter marking power between 20 D and 28 D with a power format factor between -1 and -3 and at least one second lens with a diopter marking power between 23 D and 35 D and with a power format factor that is between 0.5 and -1. Within these ranges, the anterior surface curvature and the posterior surface curvature can be refined to produce readily predictable variation in the format factor throughout the range. This stability allows for greater predictability in producing lenses capable of correcting peripheral vision while simultaneously optimizing visual acuity on the axis.
[0086] For at least one first lens in the second embodiment of the lens set, the first surface may have an anterior surface curvature between -0.022 mm-1 and 0.00 mm-1. The second surface may have a posterior surface curvature between -0.170 mm-1 and -0.081 mm-1. The center thickness may be between 0.45 mm and 1.0 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.30 mm and 0.65 mm.
[0087] For at least one second lens in the second embodiment of the lens set, the first surface may have an anterior surface curvature between 0.00 mm-1 and 0.082 mm-1. The second surface may have a posterior surface curvature between -0.179 mm-1 and -0.081 mm-1. The central thickness may be between 0.45 mm and 1.0 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.30 mm and 0.65 mm.
[0088] A third type of lens set comprises lenses with a refractive index between 1.40 and 1.50. The Petition 870250103047, dated 11 / 11 / 2025, p. 40 / 75 The 35 / 53 lens set comprises at least one first lens with a diopter marking power between 18 D and 22 D with a power format factor between -1.1 and -2.0 and at least one second lens with a diopter marking power between 24 D and 29 D and with a power format factor between -0.3 and -0.8. The lenses within this lens set comprise sub-ranges of marking power and format factor that can be selected in order to optimize the structural characteristics of the intraocular lens to result in minimized off-axis astigmatism to 20 degrees and maximized on-axis visual acuity to improve peripheral vision.
[0089] At least one first lens of the third modality of the lens set may have a first surface with an anterior surface curvature between -0.071 mm-1 and -0.00 mm-1. The second surface may have a posterior surface curvature between -0.355 mm-1 and -0.134 mm-1. The central thickness for the lens may be between 0.7 mm and 0.9 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.40 mm and 0.60 mm.
[0090] At least one second lens of the third modality of the lens set may have a first surface with an anterior surface curvature between 0 mm-1 and 0.12 mm-1. The second surface may have a posterior surface curvature between 0.36 mm-1 and 0.13 mm-1. The central thickness for the second lens may be between 0.7 mm and 0.9 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.40 mm and 0.60 mm.
[0091] The fourth type of lens set comprises lenses with a refractive index between 1.50 and 1.60. The lens set comprises at least one first lens with a diopter marking power between 20 D and 27 D with a format factor of Petition 870250103047, dated 11 / 11 / 2025, p. 41 / 75 36 / 53 power between -1.0 and -2.4 and at least one second lens with a diopter marking power between 25 D and 35 D and a power format factor between -0.7 and -0.95. The lenses within this lens set comprise sub-ranges of marking power and format factor that can be selected in order to optimize the structural characteristics of the intraocular lens to result in minimized off-axis astigmatism to 20 degrees and maximized on-axis visual acuity to improve peripheral vision.
[0092] For the first lens of the fourth modality, the first surface may have an anterior surface curvature between -0.022 mm-1 and -0.00 mm-1. The second surface may have a posterior surface curvature between -0.170 mm-1 and -0.084 mm-1. The central thickness for the first lens may be between 0.55 mm and 0.90 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.35 mm and 0.60 mm.
[0093] For at least one second lens of the fourth modality, the first surface may have an anterior surface curvature between 0.01 mm-1 and 0.082 mm-1. The second surface may have a posterior surface curvature between -0.179 mm-1 and -0.081 mm-1. The central thickness for the lens may be between 0.55 mm and 0.90 mm. An anterior haptic may be connected to the lens body to hold the lens in place after implantation, and the intraocular lens may exhibit an arc height between 0.35 mm and 0.60 mm.
[0094] A fifth embodiment of a lens set comprises at least one first lens with a refractive index between 1.40 and 1.50, a diopter marking power between 17 D and 23 D with a power format factor that is less than or equal to -1.0 and greater than or equal to -2.5 and at least one second lens with a refractive index between 1.50 and 1.60, a diopter marking power between 23 D and 35 Petition 870250103047, dated 11 / 11 / 2025, page 42 / 75 37 / 53 D and with a power format factor that is between -0.5 and -1. Within these ranges, the anterior surface curvature and the posterior surface curvature can be refined to produce readily predictable variation in the format factor across the entire range. This stability allows for greater predictability in producing lenses capable of correcting peripheral vision while simultaneously optimizing visual acuity along the axis.
[0095] A sixth embodiment of a lens set comprises at least one first lens with a refractive index between 1.50 and 1.60, a diopter marking power between 20 D and 28 D, and a power format factor between -1 and -3, and at least one second lens with a refractive index between 1.40 and 1.50 and a diopter marking power between 23 diopters and 30 diopters, and with a power format factor that is less than or equal to -0.2 and greater than or equal to -1. Within these ranges, the anterior surface curvature and the posterior surface curvature can be refined to produce readily predictable variation in the format factor throughout the range. This stability allows for greater predictability in producing lenses capable of correcting peripheral vision while simultaneously optimizing visual acuity on the axis.
[0096] A seventh embodiment of a lens set comprises at least one first lens with a refractive index between 1.50 and 1.60, a diopter marking power between 20 D and 27 D with a power format factor between -1.0 and -2.4 and at least one second lens with a refractive index between 1.40 and 1.50, a diopter marking power between 24 D and 29 D and with a power format factor that is between -0.3 and -0.8. The lenses within this lens set comprise sub-ranges of marking power and format factor that can be selected in order to optimize the structural characteristics of the intraocular lens to result in minimized off-axis astigmatism to 20 degrees and maximized on-axis visual acuity to improve peripheral vision. Petition 870250103047, dated 11 / 11 / 2025, p. 43 / 75 38 / 53
[0097] The eighth embodiment of a lens set comprises at least one first lens with a refractive index between 1.40 and 1.50, a diopter marking power between 18 D and 22 D with a power format factor between -1.1 and -2.0 and at least one second lens with a refractive index between 1.50 and 1.60, a diopter marking power between 25 D and 35 D and with a power format factor that is between -0.7 and -0.95. The lenses within this lens set comprise sub-ranges of marking power and format factor that can be selected in order to optimize the structural characteristics of the intraocular lens to result in minimized off-axis astigmatism to 20 degrees and maximized on-axis visual acuity to improve peripheral vision.
[0098] This invention uses power format factor ranges to further illustrate how lenses according to this invention can have ranges of structural values that ensure proper functioning and enhanced peripheral vision after implantation in a patient.
[0099] It is further provided that any of the lenses disclosed herein may also correct mean corneal spherical aberration, as specified in ISO 11979-2 2014, eye model no. 2. Industrial application
[0100] A method for designing an array of intraocular lenses to improve peripheral vision can be provided. The method may comprise providing an intraocular lens with an optical power that reduces optical errors in an image produced at a peripheral retinal location of a patient's eye positioned at a distance from the fovea. An intraocular lens can be provided for each increment of 0.25 D for the range of 17 D to 35 D. As the lens marking power increases from 17 D to 35 D, the power format factor increases from 3.0 to -0.2. For marking powers corresponding to a factor Petition 870250103047, dated 11 / 11 / 2025, p. 44 / 75 For formats below the transition point power, the intraocular lens comprises a first lens body with a format factor less than or equal to -1 according to the modalities discussed above. For marking powers corresponding to a format factor greater than the transition point power, the intraocular lens comprises a second lens body with a format factor greater than or equal to -1 according to the modalities discussed above. Each intraocular lens may have a defocus parameter less than 1.8 D.
[0101] Other methods for designing a lens assembly are provided for within the scope of this invention.
[0102] An intraocular lens according to this invention may also utilize complex surfaces, such as Zernike surfaces and toroidal surfaces, in addition to other variable and non-uniform surface structures for the anterior and posterior surfaces of a lens body. In a non-limiting embodiment of an intraocular lens, the first surface has an anterior radius and exhibits an anterior power; a second surface has a posterior radius and exhibits a posterior power. At least one of the first or second surfaces may be a complex surface.The intraocular lens exhibits a power format factor, relative to a constant plano-convex power format factor and corresponding to a diopter marking power, wherein the power format factor comprises a first power value, calculated with the anterior and posterior radii, and a second power value, calculated with the anterior and posterior power. The first power value and the second power value may have equal or different values for a respective diopter marking power. At least one of the first or second surfaces has a refractive profile. Complex surfaces, therefore, may use anterior and posterior radii values. Petition 870250103047, dated 11 / 11 / 2025, page 45 / 75 40 / 53 posterior variable and first variable power values. The complex surface may also include a validated power format factor having only the second power factor calculated with the anterior and posterior power. In the modalities, at least one of the first or second surfaces includes a toric surface. The power format factor for the intraocular lens has a toric surface with an average of power meridians calculated for distinct portions of the intraocular lens surfaces. In additional modalities, additional power may be added to the diopter labeling power, with the power format factor remaining equal to the second power value calculated with a baseline anterior power and a baseline posterior power.
[0103] In another embodiment of an intraocular lens according to this invention, the intraocular lens has a first surface with an anterior radius and exhibiting an anterior power and a second surface with a posterior radius and exhibiting a posterior power. Optionally, at least one of the first surface or the second surface is a complex surface with multiple curvatures through the surface. Like other lenses described above, the intraocular lens exhibits a power format factor, relative to a constant plano-convex power format factor and corresponding to a marking power measured in diopters. The power format factor may have a first power value, calculated with the anterior radius and the posterior radius, and a second power value, calculated with the anterior power and the posterior power.The first power value and the second power value may have different values for a respective diopter marking power. In non-limiting lenses of this invention, the complex surface may have variable anterior and posterior radius values and variable first power values. The complex surface may additionally include a validated power format factor calculated with only the second. Petition 870250103047, dated 11 / 11 / 2025, page 46 / 75 41 / 53 power factor, which, in turn, is calculated with the overall anterior surface power and the overall posterior surface power, where the overall powers represent the different radii of curvature. In some embodiments, at least one of the first or second surfaces includes a toric surface (i.e., exhibiting a torus or toroidal shape across at least a portion of the surface). The power shape factor for the intraocular lens having a toric surface may be an average of power meridians calculated for distinct portions of the intraocular lens. In some cases, the intraocular lenses of this invention have additional power added to the marking power, wherein the power shape factor remains equal to the second power value calculated with a baseline anterior power and a baseline posterior power.
[0104] In some situations, this invention describes relationships between optical components in terms of position or in terms of operational parameters being comparable to each other. These descriptions are not limiting to the invention, but are presented for illustrative purposes only. In fact, when this invention uses numerical values for dimensions or ranges, all numerical values are understood to be about or approximately equal, and these phrases should be given the broadest meaning in the context of the technology. In some embodiments, the magnitudes of certain optical parameters may be about a certain value or approximately equal if the magnitudes differ from each other by an amount that is within a selected range of 0 to 5 percent of the larger value. The ranges in this invention include the endpoints, unless otherwise specified or unless the context of the range dictates otherwise.
[0105] In addition to the background discussion above, this invention incorporates certain contextual information about example structures for intraocular lenses, the optical effects of these structures on patient vision and Petition 870250103047, dated 11 / 11 / 2025, page 47 / 75 42 / 53 The environment in which intraocular lenses are successfully used. As one would expect, numerous diagnostic steps occur before a physician prescribes an intraocular lens for a patient. Measurements of a patient's eye may be taken in a clinical setting, such as by an optometrist, ophthalmologist, or other medical or optical professional. Measurements may be taken by manifest refraction, autorefraction, tomography, or a combination of these or other measurement methods. The optical aberrations of the patient's eye may also be determined.
[0106] A determination of the patient's visual range can also be made. For example, the patient's ability to focus on near objects (presbyopia) can be measured and determined. An additional power range for the ophthalmic lens can be determined.
[0107] The patient's eye measurements can be put into an ophthalmic lens prescription, which includes features of at least one optical element that is intended to address the optical aberrations of the patient's eye, as well as features that address the visual range for the patient (e.g., an amount of additional power and the number of foci to be provided by the optical element).
[0108] The ophthalmic lens prescription can be used to manufacture an optical element for the ophthalmic lens. A refractive profile of the optical element can be determined based on the ophthalmic lens prescription to correct the optical aberrations of the patient's eye. Such a refractive profile can be applied to the optical element either on a surface including the diffraction profile or on an opposite optical surface. The diffraction profile can also be determined to provide the desired distribution of additional power to the optical element.
[0109] The determination of one or more refractive or diffractive profiles and the fabrication of the optical element may be performed remotely from the optometrist, ophthalmologist or other medical professional or Petition 870250103047, dated 11 / 11 / 2025, p. 48 / 75 43 / 53 optical that performed the measurements of a patient's eye or can be performed in the same clinical facility as such individual. If performed remotely, the manufactured optical element can be delivered to an optometrist, ophthalmologist, or other medical or optical professional to be provided to a patient. For an intraocular lens, the manufactured optical element can be provided for implantation in a patient's eye. The manufactured optical element can be made according to the embodiments of this invention.
[0110] The manufactured optical element may be a custom-made optical element manufactured specifically for the patient's eye, or it may be manufactured in a manufacturing set and then selected by an optometrist, ophthalmologist, or other medical or optical professional for delivery to a patient, which may include implantation in the patient's eye.
[0111] In conclusion, it should be understood that, although aspects of the present descriptive report are highlighted by reference to specific embodiments, a person skilled in the art will readily recognize that these disclosed embodiments are only illustrative of the principles of the matter disclosed herein. Therefore, it should be understood that the disclosed matter is in no way limited to a specific methodology, protocol and / or reagent, etc., described herein. Thus, various modifications or alterations or alternative configurations of the disclosed matter may be made in accordance with the teachings of the present invention without departing from the spirit of the present descriptive report. Finally, the terminology used in the present invention is intended to describe only specific embodiments and is not intended to limit the scope of systems, apparatus and methods, as disclosed herein, which is defined exclusively by the claims.Consequently, the systems, devices, and methods are not limited to precisely what is shown and described. Petition 870250103047, dated 11 / 11 / 2025, page 49 / 75 44 / 53
[0112] Certain embodiments of systems, apparatus, and methods are described herein, including the best known manner to the inventors for carrying them out. It is clear that variations in these described embodiments will become apparent to those skilled in the art upon reading the preceding description. The inventor expects that those skilled in the art will use such variations as appropriate, and the inventors intend that the systems, apparatus, and methods be carried out in a manner other than specifically described herein. Consequently, the systems, apparatus, and methods include all modifications and equivalents of the subject matter mentioned in the appended claims, as permitted by applicable law. Furthermore, any combination of the embodiments described above in all possible variations is encompassed by the systems, apparatus, and methods, except where otherwise indicated in the present invention or clearly contradicted by the context.
[0113] Groupings of alternative embodiments, components or steps of systems, apparatus and methods should not be interpreted as limitations. Each member of the group may be referred to and claimed individually or in any combination with other members of the group disclosed herein. It is foreseen that one or more members of a group may be included or excluded from a group for reasons of convenience and / or patentability. When any inclusion or exclusion occurs, the descriptive report is considered as containing the group as modified, thus fulfilling the written description of all Markush groups used in the appended claims.
[0114] The terms a, an, the / the and similarly referring terms used in the context of describing the systems, apparatus and methods (especially in the context of the following claims) should be interpreted as encompassing the singular and plural, except where indicated otherwise in the present invention or clearly contradicted by the context. Petition 870250103047, dated 11 / 11 / 2025, p. 50 / 75 45 / 53 All methods described in this invention can be carried out in any suitable order, except where otherwise indicated in this invention or otherwise clearly contradicted by the context. The use of any and all examples or illustrative language (e.g., such as) provided herein is for the sole purpose of better illuminating the systems, apparatus, and methods and does not represent a limitation on the scope of the systems, apparatus, and methods. No language in this descriptive report should be interpreted as indicating any unclaimed component essential to the practice of the systems, apparatus, and methods.
[0115] All patents, patent publications and other publications referenced and identified in this descriptive report are individually and expressly incorporated herein by reference in their entirety for the purpose of describing and disclosing, for example, the compositions and methodologies described in such publications that may be used in connection with the systems, apparatus and methods. These publications are provided only for your invention prior to the filing date of this application. Nothing to the contrary should be construed as an admission that the inventors do not have the right to advance such invention by virtue of the prior invention or for any other reason. All statements as to the date or representation as to the content of these documents are based on information available to the applicants and do not constitute any admission as to the accuracy of the dates or contents of these documents. Examples
[0116] Several aspects of the subject matter described herein are defined in the following numbered examples, which may or may not be claimed: 1. An intraocular lens comprising: a lens body, where the lens body comprises: Petition 870250103047, dated 11 / 11 / 2025, p. 51 / 75 46 / 53 a refractive index between 1.40 and 1.50 inclusive, a diopter marking power between 17 D and 23 D inclusive, and a power format factor that is less than or equal to -1.0 and greater than or equal to -2.5. 2. The intraocular lens according to example 1, where the lens comprises a diopter marking power that is between 18 D and 22 D, inclusive. 3. The intraocular lens according to example 2, where the power formatting factor is less than or equal to -1.1 and greater than or equal to -2.0. 4. The intraocular lens according to example 1, with the lens comprising a central thickness that is between 0.62 mm and 1.0 mm. 5. The intraocular lens according to example 2 or example 3, with the lens comprising a central thickness that is between 0.70 mm and 0.90 mm. 6. The intraocular lens according to example 1 or example 4, which additionally comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height that is between 0.34 mm and 0.65 mm. 7. An intraocular lens according to any one of examples 2, 3 or 5 which additionally comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height which is between 0.40 mm and 0.60 mm. 8. The intraocular lens according to any of examples 1, 4 or 6, the lens comprising a first surface with an anterior surface curvature greater than -0.077 mm-1 and less than 0.00 mm-1 and a second surface with a posterior surface curvature greater than -0.355 mm-1 and less than -0.130 mm-1. 9. The intraocular lens according to any of the examples Petition 870250103047, dated 11 / 11 / 2025, p. 52 / 75 47 / 53 2, 3, 5 or 7, with the lens comprising a first surface having an anterior surface curvature greater than -0.071 mm-1 and less than 0.00 mm-1 and a posterior surface curvature greater than -0.355 mm-1 and less than -0.134 mm-1. 10. An intraocular lens comprising: a lens body, and the lens body comprises: a refractive index between 1.50 and 1.60 inclusive, a diopter marking power between 20 D and 28 D inclusive, and a power format factor that is less than or equal to -1.0 and greater than or equal to -3. 11. The intraocular lens according to example 10, where the lens comprises a diopter marking power that is between 20 D and 27 D. 12. The intraocular lens according to example 11, where the power format factor is less than or equal to -1.0 and greater than or equal to -2.4. 13. The intraocular lens according to example 10, with the lens comprising a central thickness that is between 0.45 mm and 1.0 mm. 14. The intraocular lens according to example 11 or example 12, with the lens comprising a central thickness that is between 0.55 mm and 0.90 mm. 15. The intraocular lens according to example 10 or example 13, which further comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height that is between 0.30 mm and 0.65 mm. 16. The intraocular lens according to example 11, example 12 or example 14 which further comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height which is between 0.35 mm and 0.60 mm. Petition 870250103047, dated 11 / 11 / 2025, p. 53 / 75 48 / 53 17. The intraocular lens of example 1 or example 10, with the first surface of the lens comprising a concave surface, and the second surface comprising a convex surface with respect to an optical axis of the lens. 18. The intraocular lens of example 17, where the concave surface comprises an anterior radius of curvature of the concave surface that is greater than a posterior radius of curvature of the convex surface. 19. The intraocular lens according to any of examples 10, 13 or 15, the lens comprising a first surface with an anterior surface curvature greater than -0.022 mm-1 and less than 0.00 mm-1 and a second surface with a posterior surface curvature greater than -0.170 mm-1 and less than -0.081 mm-1. 20. The intraocular lens according to any one of examples 11, 12, 14 or 16, wherein the lens comprising a first surface having an anterior surface curvature greater than 0.022 mm-1 and less than 0.00 mm-1 and a second surface having a posterior surface curvature greater than -0.170 mm-1 and less than 0.084 mm-1. 21. An intraocular lens comprising: a lens body, and the lens body comprises: a refractive index between 1.40 and 1.50 inclusive, a diopter marking power between 23 D and 30 D inclusive, and a power format factor that is less than or equal to -0.2 and greater than or equal to -1. 22. The intraocular lens according to example 21, where the lens comprises a diopter marking power that is between 24 D and 29 D, inclusive. 23. The intraocular lens according to example 22, where the power format factor is less than or equal to -0.3 and greater than or equal to -0.8. Petition 870250103047, dated 11 / 11 / 2025, p. 54 / 75 49 / 53 24. The intraocular lens according to example 21, with the lens comprising a central thickness that is between 0.62 mm and 1.0 mm. 25. The intraocular lens according to example 22 or example 23, with the lens comprising a central thickness that is between 0.70 mm and 0.90 mm. 26. The intraocular lens according to example 21 or example 24, which further comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height that is between 0.34 mm and 0.65 mm. 27. An intraocular lens according to any of examples 22, 23 or 25 which further comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height which is between 0.40 mm and 0.60 mm. 28. The intraocular lens according to any one of examples 21, 24 or 26, wherein the lens comprising a first surface having an anterior surface curvature greater than 0 mm-1 and less than 0.120 mm-1 and a second surface having a posterior surface curvature greater than -0.367 mm-1 and less than -0.130 mm-1. 29. The intraocular lens according to any one of examples 22, 23, 25 or 27, wherein the lens comprising a first surface having an anterior surface curvature greater than 0 mm-1 and less than 0.12 mm-1 and a second surface having a posterior surface curvature greater than -0.36 mm-1 and less than -0.130 mm-1. 30. An intraocular lens comprising: a lens body, and the lens body comprises: a refractive index between 1.50 and 1.60 inclusive, a diopter marking power between 23 D and 35 D inclusive, and a power format factor that is less than or equal to -0.2 and greater than or equal to -1. Petition 870250103047, dated 11 / 11 / 2025, p. 55 / 75 50 / 53 31. The intraocular lens of Example 30, where the diopter labeling power is between 25 D and 35 D, inclusive. 32. The intraocular lens from example 31, where the power format factor is less than or equal to -0.40 and greater than or equal to 0.95. 33. The intraocular lens according to example 30, with the lens comprising a central thickness that is between 0.45 mm and 1.0 mm. 34. The intraocular lens according to example 31 or example 32, with the lens comprising a central thickness that is between 0.55 mm and 0.90 mm. 35. The intraocular lens according to example 30 or example 33, which further comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height that is between 0.30 mm and 0.65 mm. 36. An intraocular lens according to any of examples 31, 32 or 34 which further comprises an anterior haptic connected to the lens body, and wherein the lens comprises an arc height which is between 0.35 mm and 0.60 mm. 37. The intraocular lens according to any of examples 30, 33 or 35, the lens comprising a first surface having an anterior surface curvature greater than 0.00 mm-1 and less than 0.082 mm-1 and a second surface having a posterior surface curvature greater than -0.179 mm-1 and less than -0.081 mm-1. 38. The intraocular lens according to any one of examples 31, 32, 34 or 36, wherein the lens comprising a first surface having an anterior surface curvature greater than 0.01 mm-1 and less than 0.082 mm-1 and a second surface having a posterior surface curvature greater than -0.179 mm-1 and less than 0.081 mm-1. Petition 870250103047, dated 11 / 11 / 2025, p. 56 / 75 51 / 53 39. The intraocular lens of any of examples 1, 10, 21, or 30, wherein the power shape factor is calculated using paraxially defined radii of curvature of the first surface and the second surface. 40. The intraocular lens of any of the examples 1, 10, 21 or 30, where the power format factor is calculated according to the formula Ant Power - Post Power, where Ant Power is the power Antepham power is the anterior power, and postpower is the posterior power of the lens body. 41. The intraocular lens of any of the examples 1, 10, 21 or 30, wherein the power shape factor is calculated by ray tracing techniques applied to the intraocular lens. 42. The intraocular lens from example 41 above, where ray tracing techniques involve using a specific aperture size. 43. The intraocular lens from example 41 above, where ray tracing techniques involve using a specific aperture size, a better focus position, and spherical aberration effects on the power format factor. 44. The intraocular lens of any of the examples 1 to 43 that has an MTF value of at least 0.7 at a spatial frequency of 50 cycles / mm for a 5 mm pupil in green light. 45. The intraocular lens conforms to any of examples 1 to 44, wherein the intraocular lens corrects mean corneal spherical aberration as specified in ISO 11979-2 2014, Eye Model No. 2. 46. The intraocular lens according to any of examples 1 to 45, the lens comprising an anterior surface that is aspherical, or the lens comprising a posterior surface that is aspherical, or the lens comprising a posterior surface and an anterior surface that are aspherical. Petition 870250103047, dated 11 / 11 / 2025, p. 57 / 75 52 / 53 47. A set of intraocular lenses that improve peripheral vision, and the set comprises: at least one first lens conforming to any of examples 1 to 20; and at least one second lens conforming to any of examples 21 to 38. 48. The intraocular lens array according to example 47, with at least one first lens comprising a series of lenses, and the diopter marking power of each lens in the lens series differing by at least 0.25 diopters. 49. The intraocular lens array according to example 47, with at least one second lens comprising a series of lenses, and the diopter marking power of each lens in the lens series differing by at least 0.25 diopters. 50. A method for designing an array of intraocular lenses for enhanced peripheral vision, provided that as the lens marking power increases from 17 D to 35 D, the power format factor increases from -2.5 to -0.2, the method comprising: For each increment of marking power of at least 0.25 diopters, provide an intraocular lens with an optical power that reduces optical errors in an image produced at a peripheral retinal location of a patient's eye positioned at a distance from the fovea, wherein, for marking powers corresponding to a format factor less than or equal to -1, the intraocular lens comprises a lens according to any of Examples 1 to 20, wherein, for marking powers corresponding to a format factor greater than or equal to -1, the intraocular lens comprises a lens according to any of Examples 21 to 38, Petition 870250103047, dated 11 / 11 / 2025, p. 58 / 75 53 / 53 where the defocus parameter of each intraocular lens is less than 1.8 diopters, and the defocus parameter is calculated according to: Defocus parameter = jSphere2 + Cylinder2. Petition 870250103047, dated 11 / 11 / 2025, p. 59 / 75
Claims
1 / 8 CLAIMS 1. Intraocular lens, characterized in that it comprises: a lens body, wherein the lens body comprises: a refractive index between 1.40 and 1.50 inclusive, a diopter label power between 17 D and 23 D inclusive, and a power form factor that is less than or equal to -1.0 and greater than or equal to -2.5 2. Intraocular lens according to claim 1, characterized in that the lens comprises a diopter marking power between 18 D and 22 D, inclusive.
3. Intraocular lens according to claim 2, characterized in that the power form factor is less than or equal to -1.1 and greater than or equal to -2.
0.
4. Intraocular lens according to claim 1, characterized in that the lens comprises a central thickness between 0.62 mm and 1.0 mm.
5. Intraocular lens according to claim 2, characterized in that the lens comprises a central thickness between 0.70 mm and 0.90 mm.
6. Intraocular lens according to claim 1, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.34 mm and 0.65 mm.
7. Intraocular lens according to claim 2, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.40 mm and 0.60 mm.
8. Intraocular lens according to claim 1, characterized in that the lens comprises a first surface Petition 870250103047, dated 11 / 11 / 2025, p. 60 / 75 2 / 8 having an anterior surface curvature greater than 0.077 mm-1 and less than 0.00 mm-1 and a second surface having a posterior surface curvature greater than -0.355 mm-1 and less than -0.130 mm-1.
9. Intraocular lens according to claim 2, characterized in that the lens comprises a first surface having an anterior surface curvature greater than -0.071 mm-1 and less than 0.00 mm-1 and a posterior surface curvature greater than -0.355 mm-1 and less than -0.134 mm-1.
10. Intraocular lens, characterized in that it comprises: a lens body, wherein the lens body comprises: a refractive index between 1.50 and 1.60 inclusive, a diopter label power between 20 D and 28 D inclusive, and a power form factor that is less than or equal to -1.0 and greater than or equal to -3.
11. Intraocular lens according to claim 10, characterized in that the lens comprises a diopter marking power between 20 D and 27 D.
12. Intraocular lens according to claim 11, characterized in that the power form factor is less than or equal to -1.0 and greater than or equal to -2.
4.
13. Intraocular lens according to claim 10, characterized in that the lens comprises a central thickness between 0.45 mm and 1.0 mm.
14. Intraocular lens according to claim 11, characterized in that the lens comprises a central thickness between 0.55 mm and 0.90 mm.
15. Intraocular lens according to claim 10, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.30 mm and 0.65 mm.
16. Intraocular lens according to claim 11, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.35 mm and 0.60 mm.
17. Intraocular lens according to claim 1 or 10, characterized in that the first surface of the lens comprises a concave surface and the second surface comprises a convex surface with respect to an optical axis of the lens.
18. Intraocular lens according to claim 17, characterized in that the concave surface comprises an anterior radius of curvature of the concave surface that is greater than a posterior radius of curvature of the convex surface.
19. Intraocular lens according to claim 10, characterized in that the lens comprises a first surface having an anterior surface curvature greater than -0.022 mm-1 and less than 0.00 mm-1 and a second surface having a posterior surface curvature greater than -0.170 mm-1 and less than -0.081 mm-1.
20. Intraocular lens according to claim 11, characterized in that the lens comprises a first surface having an anterior surface curvature greater than -0.022 mm-1 and less than 0.00 mm-1 and a second surface having a posterior surface curvature greater than -0.170 mm-1 and less than -0.084 mm-1.
21. Intraocular lens, characterized in that it comprises: Lens body, wherein the lens body comprises: a refractive index between 1.40 and 1.50 inclusive, a diopter label power between 23 D and 30 D inclusive, and a power form factor that is less than or equal to -0.2 and greater than or equal to -1.
22. Intraocular lens according to claim 21, characterized in that the lens comprises a diopter marking power between 24 D and 29 D, inclusive.
23. Intraocular lens according to claim 22, characterized in that the power form factor is less than or equal to -0.3 and greater than or equal to -0.
8.
24. Intraocular lens according to claim 21, characterized in that the lens comprises a central thickness between 0.62 mm and 1.0 mm.
25. Intraocular lens according to claim 22, characterized in that the lens comprises a central thickness between 0.70 mm and 0.90 mm.
26. Intraocular lens according to claim 21, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.34 mm and 0.65 mm.
27. Intraocular lens according to claim 22, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.40 mm and 0.60 mm.
28. Intraocular lens according to claim 21, characterized in that the lens comprises a first surface having an anterior surface curvature greater than 0 mm-1 and less than 0.120 mm-1 and a second surface having a posterior surface curvature greater than -0.367 mm-1 and less than -0.130 mm-1.
29. Intraocular lens according to claim 22, characterized in that the lens comprises a first surface having an anterior surface curvature greater than 0 mm-1 and less than 0.12 mm-1 and a second surface having a posterior surface curvature greater than -0.36 mm-1 and less than 0.130 mm-1.
30. Intraocular lens, characterized in that it comprises: a lens body, wherein the lens body comprises: a refractive index between 1.50 and 1.60 inclusive, a diopter marking power between 23 D and 35 D inclusive, and a power form factor that is less than or equal to -0.2 and greater than or equal to -1.
31. Intraocular lens according to claim 30, characterized in that the labeled diopter power is between 25 D and 35 D, inclusive.
32. Intraocular lens according to claim 31, characterized in that the power form factor is less than or equal to -0.40 and greater than or equal to -0.
95.
33. Intraocular lens according to claim 30, characterized in that the lens comprises a central thickness between 0.45 mm and 1.0 mm.
34. Intraocular lens according to claim 31, characterized in that the lens comprises a central thickness between 0.55 mm and 0.90 mm.
35. Intraocular lens according to claim 30, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.30 mm and 0.65 mm.
36. Intraocular lens according to claim 31, characterized in that it further comprises an anterior haptic attached to the lens body, and wherein the lens comprises a dome height that is between 0.35 mm and 0.60 mm.
37. Intraocular lens according to claim 30, Petition 870250103047, dated 11 / 11 / 2025, p. 64 / 75 6 / 8 characterized in that the lens comprises a first surface having an anterior surface curvature greater than 0.00 mm-1 and less than 0.082 mm-1 and a second surface having a posterior surface curvature greater than -0.179 mm-1 and less than -0.081 mm-1.
38. Intraocular lens according to claim 31, characterized in that the lens comprises a first surface having an anterior surface curvature greater than 0.01 mm-1 and less than 0.082 mm-1 and a second surface having a posterior surface curvature greater than -0.179 mm-1 and less than -0.081 mm-1.
39. Intraocular lens according to any one of claims 1, 10, 21 or 30, characterized in that the power form factor is calculated using axially defined radii of curvature of the first surface and the second surface.
40. Intraocular lens according to any one of claims 1, 10, 21 or 30, characterized in that the power form factor is calculated according to the formula: Power of the Post Power + Post Power + Anterior Power, and Post Power is the posterior power of the lens body.
41. Intraocular lens according to any one of claims 1, 10, 21 or 30, characterized in that the power form factor is calculated by ray tracing techniques applied to the intraocular lens.
42. Intraocular lens according to claim 41, characterized in that the ray tracing techniques comprise the use of a specific aperture size.
43. Intraocular lens according to claim 41, Petition 870250103047, dated 11 / 11 / 2025, p. 65 / 75 7 / 8 characterized in that the ray tracing techniques comprise the use of a specific aperture size, best focus position and spherical aberration effects on the power form factor.
44. Intraocular lens according to any one of claims 1 to 43, characterized in that it has an MTF value of at least 0.7 at a spatial frequency of 50 cycles / mm for a 5 mm pupil in green light.
45. Intraocular lens according to any one of claims 1 to 44, characterized in that the intraocular lens corrects the mean corneal spherical aberration as specified in ISO 11979-2 2014, Eye model #2.
46. Intraocular lens according to any one of claims 1 to 45, characterized in that the lens comprises an anterior surface that is aspherical, or in that the lens comprises a posterior surface that is aspherical, or in that the lens comprises both a posterior surface and an anterior surface that are aspherical.
47. A set of intraocular lenses that improve peripheral vision, characterized in that the set comprises: at least one first lens as defined in any one of claims 1 to 20; and at least one second lens as defined in any one of claims 21 to 38.
48. Intraocular lens set according to claim 47, characterized in that at least one first lens comprises a series of lenses in which the labeled diopter power of each lens in the lens series differs by at least 0.25 diopters.
49. Intraocular lens set according to claim 47, characterized in that at least one second lens comprises a series of lenses in which the diopter label power of each lens in the lens series differs by at least 0.25 diopters.
50. A method for designing an array of intraocular lenses for enhanced peripheral vision, characterized in that the label power of the lens increases from 17 D to 35 D, the power form factor increases from -2.5 to -0.2, the method comprising: for each label power increment of at least 0.25 diopters, providing an IOL having an optical power that reduces optical errors in an image produced at a peripheral retinal location of a patient's eye disposed at a distance from the fovea, wherein for label powers corresponding to a form factor less than or equal to -1, the IOL comprises a lens as defined in any one of claims 1 to 20, wherein for label powers corresponding to a form factor greater than or equal to -1, the IOL comprises a lens as defined in any one of claims 21 to 38, wherein the obscuration parameter of each IOL is less than 1.8 diopters,where the obscurity parameter is calculated according to: Obscurity parameter = sphere2 + Cylinder2. Petition 870250103047, dated 11 / 11 / 2025, pp. 67 / 75.