CD99r as marker for alpha and beta cells

Abstract

A method for enriching glucagon producing alpha cells and / or insulin producing beta cells in a mixture of cells, comprising labelling the cell surface marker CD99R in a starting mixture of cells with a label and separating the cells that are positive for the cell surface marker from cells that are negative for the cell surface marker to obtain a final mixture of cells that is more enriched in alpha cells and / or beta cells compared to the starting mixture. A use of an antibody specific for CD99R for detecting glucagon producing alpha cells and / or insulin producing beta cells.