Methods and systems for preparing cannabis products
Patent Information
- Application Number
- CA3323950
- Authority / Receiving Office
- CA · CA
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-03-14
- Filing Date
- 2025-03-10
- Publication Date
- 2025-09-18
AI Technical Summary
Existing methods for manufacturing cannabis compositions are cumbersome, increase operation costs, and pose risks of cross-contamination and material loss, while conventional devices require multiple steps and prolonged processing times.
The use of a bladeless planetary mixer with superimposed revolution and rotation movements to liquefy and homogeneously distribute cannabis ingredients, leveraging centrifugal force and shear stress for efficient mixing without blades, ensuring uniform distribution and preserving potency.
This approach reduces processing time, minimizes cross-contamination, and maintains the quality and potency of cannabis compositions by uniformly dispersing cannabinoids and terpenes, eliminating the need for multiple devices and reducing material loss.
Abstract
Description
METHODS AND SYSTEMS FOR PREPARING CANNABIS PRODUCTSCROSS-REFERENCE TO RELATED APPLICATION
[0001] The present application claims the benefit of U.S. provisional patent application serial number 63 / 565,319 filed on March 14, 2024. The contents of the above-referenced document are incorporated herein by reference in their entirety.TECHNICAL FIELD
[0002] The present disclosure generally relates to the field of methods and systems for preparing cannabis products, and, more specifically, to methods and systems that use a bladeless planetary mixer for preparing cannabis products.BACKGROUND
[0003] With the anticipated or ongoing legalization of cannabis compositions, such as beverages, edibles for both humans and pets, vaping oils, and the like, there is a projected increase in their popularity in Canada and other nations, such as the United States, worldwide. Consequently, there is a growing focus on developing methods to produce these products on an industrial scale to meet the rising consumer demand.
[0004] Various devices is typically required to manufacture cannabis compositions, which can be cumbersome, increase operation costs, delays, likelihood of cross-contamination, or material loss. There is a need for improved methods and systems for manufacturing cannabis compositions.SUMMARY
[0005] This Summary is provided to introduce a selection of concepts in a simplified form that are further described below in the Detailed Description. This Summary is not intended to identify key aspects or essential aspects of the claimed subject matter.
[0006] In a broad aspect, the present disclosure relates to one or more of the following embodiments:1 . A process comprising a) providing a container including therein a material in a solid state which can be reversibly liquefied and one or more cannabis ingredient,b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to liquefy the material and obtain a pourable liquid cannabis composition.2. The process of embodiment 1 , wherein the material in solid state includes an edible material.3. The process of embodiment 2, wherein the edible material includes chocolate, butter, coconut oil, cocoa butter, food-grade waxes, fondant, or caramel.4. The process of any one of embodiments 1 to 3, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to cause the material to liquefy and become pourable liquid.5. The process of embodiment 4, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.6. The process of embodiment 4, wherein the operating parameter is selected from a predetermined set of operating parameters.7. The process of embodiment 4, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.8. The process of embodiment 4, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.9. A composition comprising one or more cannabis ingredient, wherein the composition is a liquid pourable cannabis composition, and wherein the one or more cannabis ingredient is substantially homogeneously distributed throughout the cannabis composition with the process of any one of embodiments 1 to 8.10. A process comprising a) providing a container including therein a solidified cannabis ingredient in a solid state, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution androtation movements are sufficient to liquefy the cannabis ingredient and obtain a pourable liquid cannabis ingredient.11. The process of embodiment 10, wherein the solidified cannabis ingredient includes a frozen concentrate or frozen distillate.12. The process of embodiment 10 or 11 , further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to cause the solidified cannabis ingredient to liquefy and become pourable liquid.13. The process of embodiment 12, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.14. The process of embodiment 12, wherein the operating parameter is selected from a predetermined set of operating parameters.15. The process of embodiment 12, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.16. The process of embodiment 12, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.17. A process comprising a) providing a container including therein one or more cannabis ingredient, an emulsifier and an aqueous solution, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to form a cannabis emulsion.18. The process of embodiment 17, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to form the cannabis emulsion.19. The process of embodiment 18, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.20. The process of embodiment 18, wherein the operating parameter is selected from a predetermined set of operating parameters.21. The process of embodiment 18, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.22. The process of embodiment 18, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.23. A cannabis composition, comprising the cannabis emulsion obtained with the process of any one of embodiments 17 to 22.24. The cannabis composition of embodiment 23, which is an edible composition, cosmetic composition, or pharmaceutical composition.25. The cannabis composition of embodiment 23, which is a transdermal or topical cream, ointment, lotion, gel, or suspension.26. The cannabis composition of any one of embodiments 23 to 25, wherein the cannabis emulsion is homogeneously distributed throughout the composition.27. A process, comprising a) providing a container including therein a cannabis ingredient and a vaping solvent, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to obtain a substantially homogenous pourable cannabis vaping composition.28. The process of embodiment 27, wherein at step a), the container further includes a carrier oil.29. The process of embodiment 27 or 28, wherein the vaping solvent includes polyethylene glycol (PEG) or vegetable glycerine (VG).30. The process of any one of embodiments 27 to 29, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to obtain the homogenous pourable cannabis vaping composition.31 . The process of embodiment 30, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.32. The process of embodiment 30, wherein the operating parameter is selected from a predetermined set of operating parameters.33. The process of embodiment 30, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.34. The process of embodiment 30, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.35. A process comprising a) providing a container including therein cannabis material particles, a cannabis extract, and a permeation agent, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, where the superimposed revolution and rotation movements are sufficient to purge the permeation agent and obtain a cannabis composition including the cannabis material particles and the cannabis extract, wherein the cannabis extract is substantially homogeneously distributed throughout the cannabis material particles.36. The process of embodiment 35, wherein the permeation agent includes ethanol.37. The process of embodiment 35 or 36, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to purge the permeation agent and obtain the cannabis composition.38. The process of embodiment 37, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.39. The process of embodiment 37, wherein the operating parameter is selected from a predetermined set of operating parameters.40. The process of embodiment 37, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.41 . The process of embodiment 37, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.42. A smokable product comprising a cannabis composition and a rolling medium containing the cannabis composition, wherein the cannabis composition includes cannabis material particles and a cannabis extract, wherein the cannabis extract is substantially homogeneously distributed throughout the cannabis material particles with the process of any one of embodiments 35 to 41 .
[0007] All features of embodiments, which are described in this disclosure and are not mutually exclusive, can be combined with one another. Elements of one embodiment can be utilized in the other embodiments without further mention. Other aspects and features of the present invention will become apparent to those ordinarily skilled in the art upon review of the following description of specific embodiments in conjunction with the accompanying figures.BRIEF DESCRIPTION OF FIGURES
[0008] The patent or application file contains at least one drawing executed in color. Copies of this patent or patent application publication with color drawing(s) will be provided by the Office upon request and payment of the necessary fee.
[0009] A detailed description of specific embodiments is provided herein below with reference to the accompanying drawings in which:
[0010] Fig. 1 shows a cross section view of a container including a cannabis composition, where the container is virtually separated in top, middle and bottom sections, each including respective top, middle and bottom layers of the cannabis composition, in accordance with embodiments of the present disclosure;
[0011] Fig. 2 is a non-limiting flow diagram of an illustrative process to obtain the cannabis composition of Fig. 1 , in accordance with embodiments of the present disclosure;
[0012] Fig. 3 shows a system for making a cannabis composition using a bladeless planetary mixer, in accordance with embodiments of the present disclosure;
[0013] Fig. 4 is a non-limiting flow diagram of an illustrative process to obtain a pourable cannabis composition, in accordance with embodiments of the present disclosure;
[0014] Fig. 5 is a non-limiting flow diagram of an illustrative process to obtain a cannabis emulsion, in accordance with embodiments of the present disclosure;
[0015] Fig. 6 is a non-limiting flow diagram of an illustrative process to blend viscous fluids, including a cannabis ingredient, in accordance with embodiments of the present disclosure;
[0016] Fig. 7 is a non-limiting flow diagram of an illustrative process to obtain a cannabis composition including cannabis particles and a cannabis extract permeated throughout the cannabis particles, in accordance with embodiments of the present disclosure.
[0017] Fig. 8A-8D are non-limiting pictures of 60g of coco butter pieces having a mean size of from about 2 inches (about 5 cm) to 3 inches (about 7.6 cm) (A)-(B), where the coco butter pieces are placed in a container (C), the container was placed in a bladeless planetary mixer and after processing, the coco butter did not fully liquefy to a pourable composition (D). Pieces were still visible and the coco butter was very viscous. The coco butter reached an internal temperature of 88°F (about 31 °C);
[0018] Fig. 9A-9D are non-limiting pictures of 60g of coco butter pieces having a mean size of from about 1 / 2 inch (about 1.3 cm) (A)-(B), where the coco butter pieces are placed in a container (C), the container was placed in a bladeless planetary mixer and after processing, the coco butter fully liquefied to a pourable composition (D), in accordance with embodiments of the present disclosure;
[0019] Fig. 10A-10D are non-limiting pictures of 60g of chocolate pieces having a mean size of from about 1.5 inches (about 3.81 cm) to about 4.5 inches (about 11.4 cm) (A)-(B), where the chocolate pieces are placed in a container (C), the container was placed in a bladeless planetary mixer and after processing, the chocolate did not fully liquefy to a pourable composition (D). Pieces were still visible and the chocolate was very viscous;
[0020] Fig. 11A-11 D are non-limiting pictures of 60g of chocolate pieces having a mean size of from about 1 inch (about 2.5 cm) to about 1.5 inches (about 3.8 cm) (A)-(B), where the chocolate pieces are placed in a container (C), the container was placed in a bladeless planetary mixer and after processing, the chocolate fully liquefied to a pourable composition (D), in accordance with embodiments of the present disclosure;
[0021] Fig. 12A-12D are non-limiting pictures of 60g of caramel pieces having a mean size of from about 5 inches (about 12.7 cm) by about 1.5 inches (about 3.81 cm) (A)-(B), where the caramel pieces are placed in a container (C), the container was placed in a bladeless planetary mixer and after processing, the caramel did not fully liquefy to a pourable composition (D). Pieces were still visible and the caramel was very viscous;
[0022] Fig. 13A-13D are non-limiting pictures of 60g of caramel pieces having a mean size of from about 1 inch (about 2.5 cm) to about 0.6 inch (about 1.5 cm) (A)-(B), where the caramel pieces are placed in a container (C), the container was placed in a bladeless planetary mixer and after processing, the caramel fully liquefied to a pourable composition (D), in accordance with embodiments of the present disclosure.
[0023] In the drawings, embodiments are illustrated by way of example. It is to be expressly understood that the description and drawings are only for the purpose of illustrating certain embodiments and are an aid for understanding. They are not intended to be a definition of the limits of the invention.DETAILED DESCRIPTION
[0024] The present technology is explained in greater detail below. This description is not intended to be a detailed catalogue of all the different ways in which the technology may be implemented, or all the features that may be added to the instant technology. For example, features illustrated with respect to one embodiment may be incorporated into other embodiments, and features illustrated with respect to a particular embodiment may be deleted from that embodiment. Further, numerous variations and additions to the various embodiments suggested herein will be apparent to those skilled in the art considering the instant disclosure which variations and additions do not depart from the present technology. Hence, the following description is intended to illustrate some embodiments of the technology, and not to exhaustively specify all permutations, combinations, and variations thereof.
[0025] The present inventor has through R&D work surprisingly and unexpectedly discovered that various cannabis compositions can be manufactured using a bladeless planetary mixer, which provides tangible benefits to a user.
[0026] The technical solution described herein employs a mixing mechanism that combines centrifugal force, shear stress, and temperature management to achieve desired outcomes in a comparatively short period of time. As a result, this technical solution preserves the potency and quality of cannabis compositions, safeguarding cannabinoids or terpenes from degradation and damage during mixing and / or purging. The herein described technical solution ensures uniform distribution and homogeneity, affords an even dispersal of desired potency throughout the composition, ultimately yielding higher quality and more potent cannabis compositions.
[0027] Further, the bladeless planetary mixer reduces the number of devices required for producing cannabis-containing compositions, which can be advantageous because using aplurality of devices can be cumbersome, increase operation costs, delays, likelihood of crosscontamination, or material loss.
[0028] These and other specific advantages will be apparent to the reader in view of the present text.Composition
[0029] A composition of the present disclosure includes one or more cannabis ingredient.
[0030] As used herein, the term “cannabis” generally refers to a genus of flowering plants that includes a number of species. There are three recognized different species, namely Cannabis sativa, Cannabis indica and Cannabis ruderalis. Hemp, or industrial hemp, is a strain of the Cannabis sativa plant species that is grown specifically for the industrial uses of its derived products.
[0031] As used herein, the term “cannabis ingredient” refers to one or more cannabis ingredient extracted from cannabis, such as a cannabinoid and / or a terpene. The cannabis ingredient may be extracted in the form of a resin, wax, concentrate, distillate, etc.
[0032] As used herein, a “cannabis extract” refers to an extract obtained from a cannabis plant material according to any procedure known in the art; such extracts yield cannabinoids in substantially pure or isolated form. For example, a cannabis extract may be obtained by a process including an extraction step from plant materials using for example organic solvent extraction, such as extraction with CO2, butane, ethanol, and the like. For example, a cannabis extract may be obtained by a process including an extraction step from plant materials using for example heat decarboxylation to convert cannabinoids in their acid forms to neutral forms followed by or after CO2extraction (under subcritical or supercritical conditions), providing a crude extract. The crude extract may then be “winterized,” that is, extracted with ethanol to remove lipids and waxes, as described for example in US 7,700,368, US 2004 / 0049059, and US 2008 / 0167483, which are incorporated herein by reference. Optionally, the method for obtaining the cannabis extract may further include purification steps such as a distillation step to further purify, isolate or crystallize one or more cannabinoids, which is referred to herein as a “distillate”; US2016 / 0346339, which is incorporated herein by reference, describes a process for extracting cannabinoids from cannabis plant material using solvent extraction followed by filtration, and evaporation of the solvent in a distiller to obtain a distillate. The distillate may be further cut with one or more terpenes. The distillate may be further purified, for example using chromatographic and other separation methods known in the art, to obtain an “isolate”.
[0033] In some embodiments, the composition of the present disclosure may include one or more cannabinoid(s).
[0034] As used herein, the term “cannabinoid” generally refers to any chemical compound that acts upon a cannabinoid receptor such as CB1 and CB2. Examples of cannabinoids include, but are not limited to, cannabichromanon (CBCN), cannabichromene (CBC), cannabichromevarin (CBCV), cannabicitran (CBT), cannabicyclol (CBL), cannabicyclovarin (CBLV), cannabidiol (CBD, defined below), cannabidiolic acid (CBDA), cannabidiol monomethylether (CBDM), cannabidiol-C4 (CBD-C4), cannabidiorcol (CBD-C1), cannabidiphorol (CBDP), cannabidivarin (CBDV), cannabielsoin (CBE), cannabifuran (CBF), cannabigerol (CBG), cannabigerol monomethylether (CBGM), cannabigerolic acid (CBGA), cannabigerovarin (CBGV), cannabinodiol (CBND), cannabinodivarin (CBVD), cannabinol (CBN), cannabinol methylether (CBNM), cannabinol propyl variant (CBNV), cannabinol-C2 (CBN-C2), cannabinol-C4 (CBN-C4), cannabiorcol (CBN-C1), cannabiripsol (CBR), cannabitriol (CBO), cannabitriolvarin (CBTV), cannabivarin (CBV), dehydrocannabifuran (DCBF), A7-cis-iso tetrahydrocannabivarin, tetrahydrocannabinol (THC, defined below), A9- tetrahydrocannabinolic acid (THC-A) including either or both isomers 2-COOH-THC (THCA- A) and 4-COOH-THC (THCA-B), A9-tetrahydrocannabiorcol (THC-C1), tetrahydrocannabivarinic acid (THCVA), tetrahydrocannabivarin (THCV), ethoxy- cannabitriolvarin (CBTVE), trihydroxy-A9-tetrahydrocannabinol (triOH-THC), 10-ethoxy- 9hydroxy-A6a-tetrahydrocannabinol, 8,9-dihydroxy-A6a-tetrahydrocannabinol, 10-oxo-A6a- tetrahydrocannabionol (OTHC), 3,4,5,6-tetrahydro-7-hydroxy-a-a-2-trimethyl-9-n-propyl-2, 6- methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), A6a,10a-tetrahydrocannabinol (A6a,10a-THC), A8-tetrahydrocannabivarin (A8-THCV), A9-tetrahydrocannabiphorol (A9- THCP), A9-tetrahydrocannabutol (A9-THCB), derivatives of any thereof, and combinations thereof. Further examples of suitable cannabinoids are discussed in at least WO2017 / 190249 and US Patent Application Pub. No. US2014 / 0271940, which are each incorporated by reference herein in their entirety.
[0035] As used herein, the term “cannabidiol” or “CBD” means one or more of the following compounds: A2-cannabidiol, A5-cannabidiol (2-(6-isopropenyl-3-methyl-5-cyclohexen-l-yl)-5- pentyl-l,3-benzenediol); A4-cannabidiol (2-(6-isopropenyl-3-methyl-4-cyclohexen-l-yl)-5- pentyl-l,3-benzenediol); A3-cannabidiol (2-(6-isopropenyl-3-methyl-3-cyclohexen-l-yl)-5- pentyl-l,3-benzenediol); A3,7-cannabidiol (2-(6-isopropenyl-3-methylenecyclohex-l-yl)-5- pentyl-l,3-benzenediol); A2-cannabidiol (2-(6-isopropenyl-3-methyl-2-cyclohexen-l-yl)-5- pentyl-l,3-benzenediol); A1 -cannabidiol (2-(6-isopropenyl-3-methyl-l-cyclohexen-l-yl)-5- pentyl-l,3-benzenediol); and A6-cannabidiol (2-(6-isopropenyl-3-methyl-6-cyclohexen-l-yl)-5-pentyl-l,3-benzenediol). In a preferred embodiment, and unless otherwise stated, CBD means A2-cannabidiol.
[0036] As used herein, the term “tetrahydrocannabinol” or “THC” means one or more of the following compounds: A8-tetrahydrocannabinol (A8-THC), A8-tetrahydrocannabivarin (A8- THCV), A9-cis-tetrahydrocannabinol (cis-THC), A9-tetrahydrocannabinol (A9-THC), A10- tetrahydrocannabinol (A10-THC), A9-tetrahydrocannabinol-C4 (THC-C4), A9- tetrahydrocannabinolic acid-C4 (THCA-C4), synhexyl (n-hexyl-A3THC). In a preferred embodiment, and unless otherwise stated, THC means one or more of the following compounds: A9-tetrahydrocannabinol and A8-tetrahydrocannabinol.
[0037] A cannabinoid may be in an acid form or a non-acid form, the latter also being referred to as the decarboxylated form since the non-acid form can be generated by decarboxylating the acid form.
[0038] In some embodiments, the composition of the present disclosure contains one or more cannabinoid(s) in an amount sufficient for the user to experience a desired effect when consuming the product. For example, the composition may include the one or more cannabinoid(s) in an amount of from about 5 wt.% to about 90 wt.%, or any value there in between, or in a range of values defined by any values there in between. For example, the composition may include the one or more cannabinoid(s) in an amount of about 90 wt.%, about 80 wt.%, about 70 wt.%, about 60 wt.%, about 50 wt.%, about 40 wt.%, about 30 wt. %, about 20 wt.%, about 15 wt.%, about 10 wt.%, or about 5 wt.%.
[0039] In some embodiments, the composition of the present disclosure may include one or more terpenes.
[0040] As used herein, the term “terpenes” generally refers to refer to a class of chemical components comprised of the fundamental building block of isoprene, which can be linked to form linear structures or rings. Terpenes may include hemiterpenes (single isoprenoid unit), monoterpenes (two units), sesquiterpenes (three units), diterpenes (four units), sesterterpenes (five units), triterpenes (six units), and so on. At least some terpenes are expected to interact with, and potentiate the activity of, cannabinoids. Examples of terpenes known to be extractable from cannabis include aromadendrene, bergamottin, bergamotol, bisabolene, borneol, 4-3-carene, caryophyllene, cineole / eucalyptol, p-cymene, dihydroj asmone, elemene, farnesene, fenchol, geranylacetate, guaiol, humulene, isopulegol, limonene, linalool, menthone, menthol, menthofuran, myrcene, nerylacetate, neomenthylacetate, ocimene, perillylalcohol, phellandrene, pinene, pulegone, sabinene,terpinene, terpineol, 4-terpineol, terpinolene, and derivatives thereof. Additional examples of terpenes include nerolidol, phytol, geraniol, alpha-bisabolol, thymol, genipin, astragaloside, asiaticoside, camphene, beta-amyrin, thujone, citronellol, 1 ,8-cineole, cycloartenol, and derivatives thereof. Further examples of terpenes are discussed in US Patent Application Pub. No. US2016 / 0250270, which is incorporated herein by reference in its entirety for all purposes.
[0041] In some embodiments, the composition of the present disclosure can be any composition suitable for containing a cannabis ingredient, such as but without being limited to food or beverage compositions, cosmetic compositions, or pharmaceutical compositions. For example, transdermal and topical creams, ointments, lotions, gels, suspensions, powders, liquid solutions (e.g., oils, beverages, etc.), troches, syrups, gummies, chocolates, honey, infusions for pre-rolls, and the like. The composition can include the cannabis ingredient per se or in any suitable form, such as in the form of an emulsion of colloidal dispersion.
[0042] In some embodiments, the composition of the present disclosure includes a cannabis ingredient homogeneously distributed throughout the composition. For example, homogeneously distributed throughout an excipient, diluent or carrier. By “substantially homogeneously distributed”, it is meant that the cannabis ingredient has a concentration which is substantially uniform throughout the composition.
[0043] Fig. 1 illustrates the concept of having substantially the same cannabis ingredient concentration in a top, middle and bottom layer of a composition 50.
[0044] Fig. 1 shows a cross-sectional view of a container 102 holding the composition 50 containing the cannabis ingredient, where the container 102 is virtually separated in top, middle and bottom sections, each including respective top 2, middle 4 and bottom 6 layers of the composition 50. The concentration of the cannabis ingredient distributed in the composition 50 is then measured in each of layers 2, 4 and 6 using a suitable technique. For example, a suitable technique may include Gas Chromatography / Mass Spectrometry (GC / MS), High-Pressure Liquid Chromatography (HPLC), Gas Chromatography / Flame Ionization Detection (GC / FID), infrared spectrum (IR) spectroscopy, ultraviolet spectrum (UV) spectroscopy, Raman spectroscopy, and the like. The standard deviation (SD) between the cannabis ingredient concentration of the three layers 2, 4 and 6 for a given composition is then determined. The relative standard deviation (%RSD), which expresses the precision and repeatability of an assay, is then calculated based on the ratio of the standard deviation to the mean.
[0045] For example, the composition can be characterized as exhibiting a concentration gradient of the cannabis ingredient having < 4% relative standard deviation (%RSD), or < 3% RSD, or < 2% RSD, or < 1% RSD, when measured at least at the top 2, middle 4 and bottom 6 layers of the composition using HPLC.
[0046] In some embodiments, the composition of the present disclosure includes a cannabis ingredient homogeneously distributed throughout an excipient, diluent or carrier in such a way that the composition has reduced air entrapment levels. One practical way of assessing air entrapment levels in the composition is to measure the specific gravity of the composition before and after the mixing procedure.
[0047] For example, the composition of the present disclosure has a specific gravity that is within 20%, or within 10%, or within 5%, or within 2%, of the specific gravity of the carrier, diluent or excipient in the absence of the cannabis ingredient. For example, the composition can have a specific gravity that is substantially identical to the specific gravity of the carrier, diluent or excipient in the absence of the cannabis ingredient.Process and mixing device
[0048] Fig. 2 is a non-limiting flow chart of a process 200 for producing the herein described composition containing a cannabis ingredient.
[0049] A non-limiting example of a system suitable to implement the process 200 is one that includes a device capable of performing superimposed revolution and rotation movements on a container that holds ingredients for making the composition. For example, a suitable device is a bladeless planetary mixer - commonly known as a bladeless planetary mixer, as the device 100 shown in Fig. 3. A bladeless planetary mixer performs superimposed revolution and rotation movements on container 102 that holds ingredients for making the composition by continually and concurrently revolving and rotating the container 102. This dual action eliminates the need for mixing rods, blades or media, or an evacuation device and can dramatically reduce processing times relative to other mixing devices that use blades to mix ingredients. Using a bladeless planetary mixer for producing compositions containing cannabis ingredients allows a uniform blend, enhancing product quality and potency. This method harnesses centrifugal force, shear stress, and precise temperature control to facilitate swift and thorough mixing, ensuring optimal results. Commercially available bladeless planetary mixers include, but without being limited to, one or more MAZTMmodels from Medisca Pharmaceutique Inc. (Canada), one or more THINKY mixer models from Thinky Corporation (Japan), one or more SpeedMixer™ models from FackTek Inc. (USA), and thelike. Bladeless planetary mixers are available in a range of sizes, from laboratory scale to industrial-scale units.
[0050] With reference to Fig. 3, the system 10 configured to perform the herein described process 200 includes a bladeless planetary mixer 100. In some embodiments, the system 10 is commercialized as a kit that includes the bladeless planetary mixer 100 and one or more containers 102, of same or variable sizes. In other embodiments, the system 10 includes the bladeless planetary mixer 100 without any container 102, where container 102 is available and sold separately. In some embodiments, the container 102 is configured to receive on a mouth 108 thereof an optional lid 106. Likewise, the lid 106 can be available and sold separately, or can be included in the system 10 as a kit. The bladeless planetary mixer 100 typically includes a basket 104 arranged eccentrically on a so-called sun wheel, at a certain distance from the centre. The basket 104 is configured to receive the container 102 therein. The planetary mixer 100 is configured to impart a revolution movement to the sun wheel and a rotational movement to the basket 104. In one example of implementation, the revolution movement is in an opposite direction to the movement of the rotation.
[0051] Returning to Fig. 2, process 200 includes step 210 of placing one or more ingredients of the desired composition in the container 102. For example, the one or more ingredients may include a cannabis ingredient. Step 220 includes placing the container 102 holding the one or more ingredients of the desired composition in the basket 104 of the planetary mixer 100. The reader will readily understand that a variant may include placing the container 102 in an empty state into the basket 104 of the planetary mixer 100 and then placing the one or more ingredients into the container 102 which is already within the basket 104 of the planetary mixer 100.
[0052] In some embodiments, the container 102 can have a size that fits in the internal space defined by the internal surface of the circumferential wall of the basket 104 such as to inhibit rotational motion of the container relative to the basket 104. In other words, at least a portion of the external surface of the circumferential wall of the container 102 can contact the internal surface of the circumferential wall of the basket 104 such that there is a friction fit between both walls to inhibit rotational motion of the container relative to the basket 104. In other embodiments, the container 102 can have a size that is smallerthan the internal space defined by the internal surface of the circumferential wall of the basket 104 such that an adapter is required to create the friction fit to inhibit rotational motion of the adapter relative to the basket 104. In other embodiments, the internal surface of the circumferential wall of the basket 104 may be provided with an engaging element 104A and the container 102 or adapter may be provided with a complementary engaging element (not shown) that engages withthe engaging element 104A. For example, one of the engaging elements may be a slot, while the other one of the engaging elements may be a protrusion or pin. Of course, many other forms of complementary engaging elements may be devised that inhibit rotational motion of the container / adapter relative to the basket 104.
[0053] Returning to Fig. 2, process 200 includes step 230 of selecting an operating parameter. For example, selecting the operating parameter may be performed through a user interface 101 present on the planetary mixer 100, as shown in Fig. 3, or through a personal computing device, such as a smartphone, a laptop, and the like (not shown). For example, selecting the operating parameter may include selecting from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, a ratio of revolution to rotation speeds, and the like. Alternatively, selecting the operating parameter may include selecting a predetermined set of operating parameters. In some embodiments, one or more of the manufacturer, the distributor, and the operator can configure the planetary mixer 100 to store the predetermined set of operating parameters on a memory device of the planetary mixer 100 or a memory device which is external to the planetary mixer 100 and communicates with the planetary mixer 100 to exchange data with the planetary mixer 100.
[0054] In some embodiments, the operation time may include a value of about 10 seconds or more, depending on the specifics of a given application. For instance, the operation time may be selected from the range of from about 10 seconds to about 15 minutes, or from about 10 seconds to about 5 minutes, including any value within one of those ranges. For example, the operation time may be of about 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 100, 120, 150, 180, 240, 300, 400, 500, 600, 700, 800, or 900 seconds, as well as any value included there in between.
[0055] Such operation time can be significantly reduced when compared to the operation time required for producing cannabis compositions with conventional devices that have mixing blades, for example. Indeed, producing cannabis compositions with conventional devices that have mixing blades may require additional time for mixing highly viscous materials (such as cannabis distillates) and / or an additional vacuum step for removing from the composition air entrapped therein resulting from the mixing blades operation. While the operation time of the present disclosure is thus relatively reduced, the shearing forces produced with the bladeless planetary mixer are sufficiently intense to produce substantially homogenous compositions, even with highly viscous materials, and is sufficiently gentle to prevent the internal temperature of the composition to degrade or evaporate cannabis ingredients, such as terpenes.
[0056] In some embodiments, the maximal G force may include a value of at least 50 g (corresponding to approximately 1490 m / s2). For example, a maximal G force value can be selected from the range of from about 50 g to about 500 g, or in the range of 50 g to 400 g, or 75 g to 350 g, or any suitable value within these ranges. Such maximal G force value provides a pressure effect which is not attainable with conventional devices that operate with blades, for example. Such pressure effect can be advantageous in specific applications that involve producing emulsions, for example.
[0057] In some embodiments, the revolution speed may include a value of at least 10 revolutions per minute (“rpm”). For example, a revolution speed can be selected from the range of from 10 to about 4000 rpm, or from 400 to about 2000 rpm, or any suitable value within these ranges.
[0058] In one embodiment, the superimposed revolution and rotation movements are operated with operational parameters that may include revolution : rotation rpm ratios of about 10:4.
[0059] In certain embodiments, the revolution rpm, the rotation rpm and the operation time are configurable parameters and their values may be individually selectable or they may be selectable from predetermined combinations of parameter values. In other embodiments, the ratio between rotation rpm and revolution rpm may be a configurable parameter and thus would constrain the revolution rpm for a certain rotation rpm or vice versa. Moreover, the geometric configuration of the planetary mixer 10 (e.g., the eccentricity (distance between the centre of rotation and the centre of revolution), the dimensions of the container 102, etc.), combined with the revolution rpm and rotation rpm, results in a certain acceleration (G force, measured in g or m / s2) being felt by the material in the container 102. In some embodiments, the desired G force may be an input provided to the planetary mixer 10, which could result in selection, by the planetary mixer 10, of the suitable revolution rpm and / or the rotation rpm.
[0060] In other embodiments, certain parameters (such as the rotation rpm or the revolution rpm) may be dynamic (i.e., vary over time) and may be input as a function of time function so as to follow a predetermined curve. There may exist still further controllable parameters of superimposed revolution and rotation movements implemented by a planetary mixer 10, such as the total weight of the container 102 holding the ingredients being mixed.
[0061] At this point, the process then includes performing the superimposed rotation and revolution movements on the container 102 to obtain the desired composition, step 240. For example, when the cannabis ingredient is present in the container 102 prior to or concomitantwith step 230, the resulting composition includes the cannabis ingredient homogeneously distributed throughout the composition.
[0062] In some embodiments, the container 102 can be a dispensing container. For example, the dispensing container can include a body configured to hold the cannabis composition and a dispensing element configured to dispense a dose of the cannabis composition. The dose can be a metered dose in which case, the dispensing element is a metering dispensing element. This implementation effectively avoids or eliminates decanting steps, thus, minimizing the risk of material loss. This implementation also reduces time required for cleaning the container 102 after producing the composition containing the cannabis ingredient, which would otherwise be required to avoid cross-contamination risks that exist when using the same container for making different compositions.
[0063] For example, the dispensing container can be a vaporization device, which can also be referred to as a vaporizer, a vaporizer pen, a vape pen, a vape, or an e-cigarette, for example. Typically, the vaporization device will include a chamber (or cartridge), a base, and a battery compartment. The chamber typically includes a mouth piece end through which a user can draw cannabis vapour from the vaporization device. In such cases, the composition could be in the form of a vaping oil, containing a cannabis oil and a vaping solvent, for example. In another example, the dispensing container can include a body enclosing the cannabis composition, an actuator manually operated, and a metering valve allowing a metered dose of the cannabis composition to be dispensed at each actuation of the actuator. Alternatively, the container can be configured to receive on a top end thereof, a dispensing system element such as a pump, a spray nozzle, applicator cap, and the like. The dispensing system can be configured to dispense metered doses as described, e.g., in US 2014 / 0221945 filed February 4, 2014, and PCT / CA2016 / 050179, filed February 23, 2016.
[0064] In some embodiments, the container can hold a composition in the form of a cream, ointment, lotion, or gel, containing a cannabis oil or cannabis emulsion, for example.
[0065] Specific implementations will now be described in the following sections.Pourable cannabis composition
[0066] Fig. 4 is a flow chart of a process 400 for producing a pourable liquid cannabis composition, in accordance with embodiments of the present disclosure.
[0067] In some applications, producing a cannabis composition may require causing a phase change of at least one ingredient. For example, when producing specific food or beverageproducts, cosmetic products, or pharmaceutical products, inducing a phase change to a solid or semi-solid ingredient to obtain a pourable liquid composition may be advantageous to incorporate and mix therein one or more cannabis ingredient.
[0068] In some embodiments, this phase change may be implemented by performing the herein described superimposed revolution and rotation movements on a container holding particles of the ingredient in a solid or semi-solid state, where the movements are sufficient to obtain the pourable liquid composition. In other words, the superimposed movements being sufficient to cause the phase change means that the addition of external heat is not required to obtain the pourable liquid composition - the person of skill may wish nevertheless to add external heat to accelerate the phase change, but this is not required. The reader will readily understand that this process manages temperature and operation time, thus improving product quality and potency, as discussed previously.
[0069] In this process 400, superimposed revolution and rotation movements are performed on a container holding particles of a material in a solid or semi-solid state. The material can include a solidified cannabis ingredient or an edible material, for example. The size of the particles can vary, while still achieving a successful liquefaction (e.g., melting). In a specific example, particles in the shape of chunks, which tend to be in the millimeters (mm) to centimeters (cm) or even larger range, can be reliably liquefied in a bladeless planetary mixer to obtain a pourable liquid composition.
[0070] A cannabis ingredient can be solidified to a solid or semi-solid state. For example, cannabis oils (concentrate or distillate) can be frozen to achieve the solid or semi-solid state, typically at temperatures such as -20°C or -80°C. For example, cannabinoids can be purified to obtain cannabis crystals through solvent evaporation, cooling, or seeding (introducing small crystals to encourage the growth of larger ones). Solidifying a cannabis ingredient offers numerous advantages in terms of facilitating easier and more accurate handling and weighing (minimizing the chances of spills or losses with sticky oils, etc.).
[0071] Various edible materials may be used with this process in order to reversibly liquefy and infuse therein with one or more cannabis ingredient. Non-limiting examples of suitable edible materials include chocolate to create various confections, coatings, or desserts; butter to combine with other ingredients to make sauces, spreads, and baked goods; coconut oil to blend with other ingredients to make baked goods, snacks, and beauty products; cocoa butter to combine with cocoa powder and sweeteners to make chocolate products; food-grade waxes such as beeswax or paraffin that can be used in various culinary applications, including candymaking and coating; specific types of sugar, such as fondant or caramel, which can be liquefied and mixed to create sweet treats and decorations; and the like.
[0072] The process 400 includes step 410 of placing particles of the material in a solid or semi-solid state in the container 102. When the material is an edible material, then the cannabis ingredient may be incorporated into the container 102 before, concurrently or after step 410, shown as step 415. When the material is frozen cannabis oil, then step 415 is not applicable.
[0073] Step 420 includes placing the container 102 holding the particles of the material in a solid or semi-solid state in the basket 104 of the planetary mixer 100. The reader will readily understand that a variant may include placing the container 102 in an empty state into the basket 104 of the planetary mixer 100 and then placing the particles of the material in a solid or semi-solid state into the container 102 which is already within the basket 104 of the planetary mixer 100.
[0074] The process 400 then includes step 430 of selecting the operating parameter. As discussed previously, the operating parameter may be selected through the user interface 101 present on the planetary mixer 100, as shown in Fig. 3, or through a personal computing device, such as a smartphone, a laptop, and the like (not shown).
[0075] The process 400 then includes step 440 of performing the superimposed rotation and revolution movements on the container 102 to obtain the pourable liquid cannabis composition.
[0076] The reader will readily understand that when processing an edible material to obtain a pourable liquid composition, the cannabis ingredient can be added prior to, concomitant with, or after step 410 or 420. Alternatively, the cannabis ingredient can be added after the pourable liquid composition has been obtained, as shown with the returning arrow 450. The cannabis ingredient is then added as step 415 into the pourable liquid composition for mixing therein with steps 430, 440 to obtain the pourable liquid composition.
[0077] Without being bound by any theory, it is believed that the superimposed revolution and rotation movements can liquefy (e.g., melt) the solid or semi-solid particles through the impact of the particles against each other and / or against the container walls, the intense G forces acting on the material and thus creating a shear action and possibly other phenomena, which in combination generate thermal energy, which heats-up the material sufficiently to reach its melting point, without requiring the addition of external heat.
[0078] The resulting pourable liquid composition containing the cannabis ingredient can be used for incorporating into an edible composition (food or beverage), cosmetic composition, or pharmaceutical composition. Alternatively, the resulting pourable liquid composition can be poured into a mould having a desired shape and allowed to solidify to obtain a solid cannabis composition having the desired shape.Cannabis emulsions
[0079] Fig. 5 is a flow chart of a process 500 for producing a cannabis emulsion, in accordance with embodiments of the present disclosure.
[0080] In some applications, producing a cannabis-infused composition may require encapsulating one or more cannabis ingredient in an emulsion to facilitate mixing and / or incorporation of the one or more cannabis ingredient into a water-containing composition. For example, when producing specific food or beverage products, cosmetic products, or pharmaceutical products that are water-containing compositions, incorporating the one or more cannabis ingredient in an emulsion facilitates infusion thereof.
[0081] Producing a cannabis emulsion entails braking down cannabis oil or extract into tiny droplets (e.g., nanometre or micrometre sizes) and dispersing them throughout a liquid medium. This process typically involves the use of emulsifiers and mixing techniques to stabilize the mixture. Conventional mechanical mixing techniques such as high shear mixing, sonication, or homogenization are used to break down the cannabis oil into droplets and disperse these evenly throughout the liquid medium.
[0082] In this process 500, superimposed revolution and rotation movements are performed on a container holding one or more cannabis ingredient, an emulsifier and a liquid medium to obtain a cannabis emulsion. For example, the liquid medium may optionally include a carrier oil, and include an aqueous solution.
[0083] The purpose of the carrier oil or solvent is to aid in solubilizing the hydrophobic cannabinoids in the emulsion. Non-limiting examples of suitable carrier oils or solvents include, but are not limited to, borage oil, coconut oil, cottonseed oil, soybean oil, safflower oil, sunflower oil, castor oil, corn oil, olive oil, palm oil, peanut oil, almond oil, sesame oil, rapeseed oil, peppermint oil, poppy seed oil, canola oil, palm kernel oil, hydrogenated soybean oil, hydrogenated vegetable oils, glyceryl esters of saturated fatty acids, glyceryl behenate, glyceryl distearate, glyceryl isostearate, glyceryl laurate, glyceryl monooleate, glyceryl, monolinoleate, glyceryl palmitate, glyceryl palmitostearate, glyceryl ricinoleate, glyceryl stearate, polyglyceryl 10-oleate, polyglyceryl 3-oleate, polyglyceryl 4-oleate, polyglyceryl 10-tetralinoleate, behenic acid, medium-chain triglycerides (e.g., caprylic / capric glycerides), ethanol, acetone, isopropanol, hydrocarbons or a combination thereof.
[0084] The purpose of the emulsifier is to act as surfactant and to reduce a surface tension at an interface between the oil and the aqueous solution. The one or more emulsifiers may be ionic, nonionic or a combination of both. In some non-limiting examples, the emulsifier may be a poloxamer, polysorbate, polyoxyethylene, polyoxypropylene block co-polymer, ethoxylated aliphatic alkyl alcohol, ethoxylated fatty alcohol, ethoxylated aliphatic alkyl acid, ethoxylated fatty acid, glyceryl monostearate, sorbitan fatty acid ester, capril caprylic macrogoglyceride, propylene glycol laurate, propylene glycol caprylate, glycerol monostrearate, polyglycerol oleate, lecithin-based emulsifier, tocopherol, polyoxyethylene or any combination therefore, and specifically polyoxyethylene monostearate (PEG 400 Monostearate), polyoxyethylene monooleate (PEG 400 Monoleate), polyoxyethylene sorbitan monolaurate (Tween™ 20), polyoxyethylene sorbitan monolaurate (Tween 21), polyoxyethylene sorbitan monopalmitate (Tween 40), polyoxyethylene sorbitan monostearate (Tween 60), polyoxyethylene sorbitan monostearate (Tween 61), polyoxyethylene sorbitan tristearate (Tween 65), polyoxyethylene sorbitan monooleate (Tween 80), polyoxyethylene sorbitan monooleate (Tween 81), polyoxyethylene sorbitan trioleate (Tween 85), polyoxyethylene-(15)-stearic acid (Pegosperse 1500M5), polyoxyethylene-(20)-stearyl alcohol (Brij 78), polyoxyethylene-(23)-lauryl alcohol (Brij 35), (Lutensol ON 60), PEG-40 hydrogenated castor oil (Cremophor / Kolliphor RH 40), PEG-35 castor oil (Cremophor EL), Solutol HS-15, sorbitan monopalmitate (Span 40), sorbitan monostearate (Span 60), sorbitan tristearate (Span 65), sorbitan monooleate (Span 80), sorbitan trioleate (Span 85), sunflower lecithin emulsifier, soybean lecithin emulsifier, linseed lecithin emulsifier, olive lecithin emulrapeseed lecithin emulsifier, egg lecithin emulsifier, corn lecithin emulsifier, peanut lecithin emulsifier, algal lecithin emulsifier, Vitamin E and Vitamin E derivatives (alpha, beta, gamma and delta-tocopherols), preferably d-alpha-tocopherol polyethyleneglycol 1000 succinate (Vitamin E TPGS), blend of isomers of alpha-tocopherol, beta-tocopherol, gamma-tocopherol and delta-tocopherol (Tocobior), polyoxyethylene (2) cetyl ether (Brij C2), Quillaja extract (saponin), and any combination thereof. Any other suitable ionic or nonionic emulsifier may be used in other non-limiting examples.
[0085] The process 500 includes step 510 of placing one or more cannabis ingredient and an emulsifier in the container 102. For example, the one or more cannabis ingredient and the emulsifier may have been previously mixed to obtain a cannabis-emulsifier mixture. Alternatively, shown with arrow 550, the one or more cannabis ingredient and the emulsifier can be mixed with the herein described superimposed revolution and rotation movementsbefore proceeding to step 515 of adding a liquid medium into the container 102 to contact the cannabis-emulsifier mixture after step 510.
[0086] Step 520 includes placing the container 102 holding the one or more cannabis ingredient and emulsifier in the basket 104 of the planetary mixer 100. The reader will readily understand that a variant may include placing the container 102 in an empty state into the basket 104 of the planetary mixer 100 and then placing the one or more cannabis ingredient and emulsifier into the container 102 which is already within the basket 104 of the planetary mixer 100.
[0087] The process 500 then includes step 530 of selecting the operating parameter. As discussed previously, the operating parameter may be selected through the user interface 101 present on the planetary mixer 100, as shown in Fig. 3, or through a personal computing device, such as a smartphone, a laptop, and the like (not shown).
[0088] The process 500 then includes step 540 of performing the superimposed rotation and revolution movements on the container 102 to obtain the cannabis emulsion.
[0089] Without being bound by any theory, it is believed that the shear forces and / or pressure obtained with the superimposed revolution and rotation movements are sufficient to obtain the cannabis emulsion, even with highly viscous materials (e.g., cannabis distillate, or viscous liquid medium). Further, it has been observed that a stable emulsion can be obtained with significantly less concentration of emulsifier compared to conventional approaches - which can contribute to less bitter taste for food and beverages applications (emulsifiers are known to have a bitter taste).
[0090] The resulting cannabis emulsion can be used for incorporating into a water-containing composition, for example, to produce a beverage, cosmetics, or pharmaceutical composition.Blending viscous materials
[0091] Fig. 6 is a flow chart of a process 600 for producing a cannabis composition with relatively highly viscous materials, in accordance with embodiments of the present disclosure.
[0092] Traditionally, blending liquid substances has relied on rotating blades or vanes submerged within the substances. Yet, this approach encounters challenges when dealing with highly viscous materials. Mixing highly viscous materials demands robust rotors capable of high torque and significant input power. Despite these measures, viscous materials still necessitate prolonged mixing durations to guarantee uniform blends, with materials at container corners often remaining insufficiently mixed. Additionally, high-speed stirringintroduces considerable amounts of air into the mixture, requiring subsequently deaerating prior to utilization.
[0093] In contrast, the herein described superimposed revolution and rotation movements will not introduce air during the mixing process, and if the starting composition ingredients (i.e., before mixing) initially include air entrapped therein, the herein described superimposed revolution and rotation movements will deaerate the composition while mixing the ingredients.
[0094] In this process 600, superimposed revolution and rotation movements are performed on a container holding a viscous mixture including one or more cannabis ingredient and a liquid medium to obtain a cannabis composition.
[0095] Viscosity is the measure of substance resistance to motion or flow under an applied force and is expressed as Centipoise (cP) or as Pascal-second (Pa-s), where 1 cP = 1 mPas-s. The viscosity of cannabis oil is influenced by the CBD, THC and terpene content in the oil. Distillate usually contains mainly cannabinoids with the highest concentrations of up to 80- 90%, whereas live resin has concentrations closer to 40-50%. For example, there have been reports of cannabis oils extracted with CO2having viscosity values of 5000-8000 cP at 40°C and some measurements have even reached up to 300,000 1 / s at 15°C. Carriers used for making vaping oils such as polyethylene glycol (PEG) or vegetable glycerine (VG), have a viscosity that can vary depending on a number of factors. The viscosity of polyethylene glycol (PEG) can vary depending on factors such as its molecular weight and temperature. For example, low molecular weight PEGs may have viscosities in the range of 1-20 cP, while higher molecular weight PEGs can have viscosities ranging from 1000 to 10000 cP or more. Vegetable glycerine, also known as glycerol or glycerine, is a thick, syrupy liquid with a relatively high viscosity. Its viscosity can vary depending on factors such as temperature, purity, and concentration. At room temperature (around 25°C or 77°F), vegetable glycerine typically has a viscosity ranging from approximately 1500 to 6000 centipoise (cP) or millipascal-seconds (mPa s).
[0096] The process 600 includes step 610 of placing one or more cannabis ingredient and a liquid medium in the container 102. For example, the one or more cannabis ingredient and the liquid medium may form a mixture having a viscosity of at least 5000 cP at 40°C. For example, the liquid medium may include a vaping solvent, such as PEG or VG, and optionally a carrier oil, such as MOT.
[0097] Step 620 includes placing the container 102 holding the one or more cannabis ingredient and liquid medium in the basket 104 of the planetary mixer 100. The reader willreadily understand that a variant may include placing the container 102 in an empty state into the basket 104 of the planetary mixer 100 and then placing the one or more cannabis ingredient and liquid medium into the container 102 which is already within the basket 104 of the planetary mixer 100. The reader will readily understand that in yet another variant, the process may include placing the container 102 with one of the one or more cannabis ingredient and liquid medium held therein into the basket 104 of the planetary mixer 100 and then placing the other one of the one or more cannabis ingredient and liquid medium into the container 102 while it sits in the basket 104 of the planetary mixer 100.
[0098] The process 600 then includes step 630 of selecting the operating parameter. As discussed previously, the operating parameter may be selected through the user interface 101 present on the planetary mixer 100, as shown in Fig. 3, or through a personal computing device, such as a smartphone, a laptop, and the like (not shown).
[0099] The process 600 then includes step 640 of performing the superimposed rotation and revolution movements on the container 102 to obtain the cannabis composition. When the one or more cannabis ingredient is blended with a vaping solvent, the superimposed rotation and revolution movements on the container 102 are sufficient to reduce a viscosity of the cannabis vaping composition to facilitate blending of the one or more cannabis ingredient and the solvent so as to obtain a potency homogeneity.
[0100] The resulting cannabis composition can be used for incorporating into an edible composition (food or beverage), cosmetic composition, or pharmaceutical composition. When the one or more cannabis ingredient is blended with a vaping solvent, the resulting cannabis vaping composition can be used in a vaping device.Infused pre-rolls
[0101] Fig. 7 is a flow chart of a process 700 for producing a cannabis composition which includes cannabis material particles infused with one or more cannabis ingredient, in accordance with embodiments of the present disclosure.
[0102] Processing cannabis material to produce smokable marijuana products (“pre-rolls”) often involves hand rolling or mechanical equipment that utilizes air pressure, vibration, and pressure. Hand rolling, while traditional, is too inconsistent and inefficient for large-scale commercial production. Using machines to produce acceptable smokable products poses challenges due to potential input degradation and the limitations imposed by the machinery involved. Sticky materials, in particular, present difficulties, as they tend to adhere to and clog machine components. Manufacturers aiming to control cannabinoid content often face issueswith such materials, exacerbated when a cannabis extract is not evenly dispersed, leading to localized accumulations that are especially adhesive.
[0103] In contrast, the herein described superimposed revolution and rotation movements are sufficient to obtain a cannabis composition which includes cannabis particles and a cannabis extract permeated (e.g., homogeneously distributed) throughout the cannabis particles (e.g., instead of merely at a surface or periphery of an aggregation of the cannabis particles). In some embodiments, this may be achieved with a permeation agent contacting the cannabis particles and the cannabis extract during permeation of the cannabis extract throughout the cannabis particles, as described for example in WO2023115215, which is hereby incorporated by reference. For instance, in some examples, the permeation agent may be alcohol (e.g., ethanol) or another solvent or other suitable substance that is incorporated into the cannabis extract to facilitate permeation of the cannabis extract throughout the cannabis particles (e.g., which may be initially dry cannabis particles). In some cases, at least a majority (e.g., the majority or an entirety) of the permeation agent may be removed from the smokable product after permeation of the cannabis extract throughout the cannabis particles, e.g., by purging the solvent with the herein described superimposed revolution and rotation movements.
[0104] In some embodiments, the present disclosure thus relates to a smokable product containing a cannabis composition and a rolling medium containing the cannabis composition, wherein the cannabis composition includes cannabis particles and a cannabis extract, wherein the cannabis extract is substantially homogeneously distributed (permeated) throughout the cannabis particles.
[0105] The process 700 includes step 710 of placing the cannabis material in particle form, one or more cannabis ingredients, and the permeation agent in the container 102.
[0106] Step 620 includes placing the container 102 holding the cannabis material in particle form, one or more cannabis ingredients, and the permeation agent in the basket 104 of the planetary mixer 100. The reader will readily understand that a variant may include placing the container 102 in an empty state into the basket 104 of the planetary mixer 100 and then placing the cannabis material in particle form (i.e., cannabis material particles), one or more cannabis ingredients, and the permeation agent into the container 102 which is already within the basket 104 of the planetary mixer 100. The reader will readily understand that in yet another variant, the process may include placing the container 102 with one of the cannabis material in particle form, one or more cannabis ingredients, and the permeation agent held therein into the basket 104 of the planetary mixer 100 and then placing the missing of the cannabis material in particleform, one or more cannabis ingredients, and the permeation agent into the container 102 while it sits in the basket 104 of the planetary mixer 100.
[0107] The process 700 then includes step 730 of selecting the operating parameter. As discussed previously, the operating parameter may be selected through the user interface 101 present on the planetary mixer 100, as shown in Fig. 3, or through a personal computing device, such as a smartphone, a laptop, and the like (not shown).
[0108] The process 700 then includes step 740 of performing the superimposed rotation and revolution movements on the container 102 to obtain a cannabis composition which includes cannabis particles and a cannabis oil permeated (e.g., homogeneously distributed) throughout the cannabis particles.Use of cannabis containing composition
[0109] The cannabis containing composition as described herein is typically used for recreational, cosmetics, or medicinal uses. For example, the composition can be used to achieve a desired effect in a user, such as a psychoactive effect, a physiological effect, or a treatment of a condition. By “psychoactive effect”, it is meant a substantial effect on the mood, perception, consciousness, cognition, or behaviour of a subject resulting from changes in the normal functioning of the nervous system. By “physiological effect”, it is meant as an effect associated with a feeling of physical and / or emotional satisfaction. By “treatment of a condition”, it is meant for the treatment or alleviation of a disease or condition by absorption of cannabinoid(s) at sufficient amounts to mediate the therapeutic or cosmetic effects.
[0110] The terms “treating”, “treatment” and the like are used herein to mean obtaining a desired pharmacologic and / or physiologic effect. The effect may be prophylactic, in terms of completely or partially preventing a disease, condition, or symptoms thereof, and / or may be therapeutic in terms of a partial or complete cure for a disease or condition and / or adverse effect, such as a symptom, attributable to the disease or disorder. “Treatment” as used herein covers any treatment of a disease or condition of a mammal, such as a dog, cat or human, preferably a human.
[0111] In certain embodiments, the disease or condition is selected from the group consisting of pain, anxiety, an inflammatory disorder, a neurological disorder, a psychiatric disorder, a malignancy, an immune disorder, a metabolic disorder, a nutritional deficiency, an infectious disease, a gastrointestinal disorder, and a cardiovascular disorder. Preferably, the disease or condition is pain. In other embodiments, the disease or condition is associated with the feeling of physical and / or emotional satisfaction.
[0112] In the context of recreational use, the “effective amount” administered and rate and time course of administration, will depend on the desired effect associated with a feeling of physical and / or emotional satisfaction in the subject.
[0113] In the context of health and wellness use, the “effective amount” administered and rate and time course of administration will depend on the nature and severity of the disease or condition being treated and typically takes into consideration the condition of the individual subject, the method of administration and the like.
[0114] The present disclosure has described various applications for producing a cannabis composition using a bladeless planetary mixer configured to perform superimposed revolution and rotation movements on a container holding ingredients for making the cannabis composition. Using such a device affords several technical advantages.
[0115] For example, achieving uniformity in cannabis compositions (which can be a challenging task with conventional approaches due to viscosity issues) can be efficiently implemented in a bladeless planetary mixer without compromising flavour or aroma. Traditional methods often involve time-consuming and intricate processes that necessitate heat, risking the degradation of valuable terpenes and diminishing potency.
[0116] For example, reducing the viscosity and consistency of cannabis oils or distillates to manageable levels and effectively blending them with oils or flavours (e.g., for vape cartridges applications) can prove challenging with conventional approaches. The technical solution described herein efficiently addresses these challenges by efficiently homogenizing cannabis oils or distillates with other ingredients, with relatively high viscosities. The technical solution described herein overcomes viscosity issues and ensures consistent blending with delicate terpenes, oils, or flavours.
[0117] For example, swift and efficient removal of air, moisture or hydrocarbon solvents without compromising cannabis compositions integrity (which can be difficult with conventional methods and devices) can be efficiently implemented in a bladeless planetary mixer. Indeed, the process of purging air, moisture, or hydrocarbon solvents (such as butane, hexane, ethanol, CO2or propane) from cannabis compositions can be arduous and time-consuming with conventional methods. Typically, it can span over several days, and utilizing a vacuum oven might diminish the potency of cannabinoids, thereby affecting the overall quality and safety of the cannabis composition due to residual solvents. The present technical solution facilitates rapid and effective solvent purging from cannabis compositions, substantially cutting down the purging time and providing a quicker alternative to conventional methods. The hereindescribed controlled procedure aids in solvent removal while minimizing the risk of product damage. Moreover, it significantly reduces the space and energy requirements compared to traditional vacuum oven methods.EXAMPLES
[0118] The following examples describe some exemplary modes of making and practicing certain compositions that are described herein. These examples are for illustrative purposes only and are not meant to limit the scope of the compositions and methods described herein.Comparative Example 1
[0119] 60g of coco butter pieces having a mean size of from about 2 inches (about 5 cm) to 3 inches (about 7.6 cm) were placed in a container (Fig. 8A-8C). The container was placed in a bladeless MAZTMplanetary mixer (model KK-400W), which performed superimposed revolution and rotation movements on the container with the following parameters: 2 minutes at level 9 revolution and level 9 rotation. The coco butter did not fully liquefy to a pourable composition (Fig. 8D). Pieces were still visible and the coco butter was very viscous. The coco butter reached an internal temperature of 88°F (about 31 °C).Example 1
[0120] 60g of coco butter pieces having a mean size of from about 1 / 2 inch (about 1.3 cm) (A)-(B) were placed in a container (Fig. 9A-9C). The container was placed in a bladeless MAZ™ planetary mixer (model KK-400W), which performed superimposed revolution and rotation movements on the container with the following parameters: 2 minutes at level 9 revolution and level 9 rotation. The coco butter fully liquefied to a pourable composition (Fig. 9D). The coco butter reached an internal temperature of 88°F (about 31 °C).Comparative Example 2
[0121] 60g of chocolate pieces having a mean size of from about 1.5 inches (about 3.81 cm) to about 4.5 inches (about 11.4 cm) were placed in a container (Fig. 10A-10C). The container was placed in a bladeless MAZ™ planetary mixer (model KK-400W), which performed superimposed revolution and rotation movements on the container with the following parameters: 2 minutes at level 9 revolution and level 9 rotation. The chocolate did not fully liquefy to a pourable composition (Fig. 10D). Pieces were still visible and the chocolate was very viscous. The chocolate reached an internal temperature of 122°F (about 50°C).Example 2
[0122] 60g of chocolate pieces having a mean size of from about 1 inch (about 2.5 cm) to about 1.5 inches (about 3.8 cm) were placed in a container (Fig. 11A-11C). The container was placed in a bladeless MAZTMplanetary mixer (model KK-400W), which performed superimposed revolution and rotation movements on the container with the following parameters: 2 minutes at level 9 revolution and level 9 rotation. The chocolate fully liquefied to a pourable composition (Fig. 11 D). The chocolate reached an internal temperature of 133°F (about 56°C).Comparative Example 3
[0123] 60g of caramel pieces having a mean size of from about 5 inches (about 12.7 cm) by about 1.5 inches (about 3.81 cm) were placed in a container (Fig. 12A-12C). The container was placed in a bladeless MAZTMplanetary mixer (model KK-400W), which performed superimposed revolution and rotation movements on the container with the following parameters: 2 minutes at level 9 revolution and level 9 rotation. The caramel did not fully liquefy to a pourable composition (Fig. 12D). Pieces were still visible and the caramel was very viscous. The caramel reached an internal temperature of 178°F (about 81 °C).Example 3
[0124] 60g of caramel pieces having a mean size of from about 1 inch (about 2.5 cm) to about 0.6 inch (about 1.5 cm) were placed in a container (Fig. 13A-13C). The container was placed in a bladeless MAZTMplanetary mixer (model KK-400W), which performed superimposed revolution and rotation movements on the container with the following parameters: 2 minutes at level 9 revolution and level 9 rotation. The caramel fully liquefied to a pourable composition (Fig. 13D). The caramel reached an internal temperature of 181 °F (about 82°C).
[0125] These and other advantages will be readily understandable to the reader in view of the teachings of the present description.
[0126] Other examples of implementations will become apparent to the reader in view of the teachings of the present description and as such will not be further described here.
[0127] Note that titles or subtitles may be used throughout the present disclosure for the convenience of a reader, but in no way these should limit the scope of the invention. Moreover, certain theories may be proposed and disclosed herein; however, in no way they, whether they are right or wrong, should limit the scope of the invention so long as the invention ispractised according to the present disclosure without regard for any particular theory or scheme of action.
[0128] All references cited throughout the specification are hereby incorporated by reference in their entirety for all purposes.
[0129] It will be understood by those of skill in the art that throughout the present specification, the term “a” used before a term encompasses embodiments containing one or more to what the term refers. It will also be understood by those of skill in the art that throughout the present specification, the term “comprising”, which is synonymous with “including,” “containing,” or “characterized by,” is inclusive or open-ended and does not exclude additionally, un-recited elements or method steps.
[0130] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure pertains. In the case of conflict, the present document, including definitions will control.
[0131] As used in the present disclosure, the terms “around”, “about” or “approximately” shall generally mean within the error margin generally accepted in the art. Hence, numerical quantities given herein generally includes such error margin such that the terms “around”, “about” or “approximately” can be inferred if not expressly stated.
[0132] Although various embodiments of the disclosure have been described and illustrated, it will be apparent to those skilled in the art in light of the present description that numerous modifications and variations can be made. The scope of the invention is defined more particularly in the appended claims.
Claims
CLAIMS1 . A process comprising a) providing a container including therein a material in a solid state which can be reversibly liquefied and one or more cannabis ingredient, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to liquefy the material and obtain a pourable liquid cannabis composition.
2. The process of claim 1 , wherein the material in solid state includes an edible material.
3. The process of claim 2, wherein the edible material includes chocolate, butter, coconut oil, cocoa butter, food-grade waxes, fondant, or caramel.
4. The process of any one of claims 1 to 3, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to cause the material to liquefy and become pourable liquid.
5. The process of claim 4, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.
6. The process of claim 4, wherein the operating parameter is selected from a predetermined set of operating parameters.
7. The process of claim 4, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.
8. The process of claim 4, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.
9. A composition comprising one or more cannabis ingredient, wherein the composition is a liquid pourable cannabis composition, and wherein the one or more cannabis ingredient is substantially homogeneously distributed throughout the cannabis composition with the process of any one of claims 1 to 8.
10. A process comprisinga) providing a container including therein a solidified cannabis ingredient in a solid state, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to liquefy the cannabis ingredient and obtain a pourable liquid cannabis ingredient.
11. The process of claim 10, wherein the solidified cannabis ingredient includes a frozen concentrate or frozen distillate.
12. The process of claim 10 or 11 , further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to cause the solidified cannabis ingredient to liquefy and become pourable liquid.
13. The process of claim 12, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.
14. The process of claim 12, wherein the operating parameter is selected from a predetermined set of operating parameters.
15. The process of claim 12, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.
16. The process of claim 12, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.
17. A process comprising a) providing a container including therein one or more cannabis ingredient, an emulsifier and an aqueous solution, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to form a cannabis emulsion.
18. The process of claim 17, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to form the cannabis emulsion.
19. The process of claim 18, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.
20. The process of claim 18, wherein the operating parameter is selected from a predetermined set of operating parameters.21 . The process of claim 18, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.
22. The process of claim 18, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.
23. A cannabis composition, comprising the cannabis emulsion obtained with the process of any one of claims 17 to 22.
24. The cannabis composition of claim 23, which is an edible composition, cosmetic composition, or pharmaceutical composition.
25. The cannabis composition of claim 23, which is a transdermal or topical cream, ointment, lotion, gel, or suspension.
26. The cannabis composition of any one of claims 23 to 25, wherein the cannabis emulsion is homogeneously distributed throughout the composition.
27. A process, comprising a) providing a container including therein a cannabis ingredient and a vaping solvent, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, wherein the superimposed revolution and rotation movements are sufficient to obtain a substantially homogenous pourable cannabis vaping composition.
28. The process of claim 27, wherein at step a), the container further includes a carrier oil.
29. The process of claim 27 or 28, wherein the vaping solvent includes polyethylene glycol (PEG) or vegetable glycerine (VG).
30. The process of any one of claims 27 to 29, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to obtain the homogenous pourable cannabis vaping composition.31 . The process of claim 30, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.
32. The process of claim 30, wherein the operating parameter is selected from a predetermined set of operating parameters.
33. The process of claim 30, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.
34. The process of claim 30, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.
35. A process comprising a) providing a container including therein cannabis material particles, a cannabis extract, and a permeation agent, b) subjecting the container to superimposed revolution and rotation movements in a bladeless planetary mixer, where the superimposed revolution and rotation movements are sufficient to purge the permeation agent and obtain a cannabis composition including the cannabis material particles and the cannabis extract, wherein the cannabis extract is substantially homogeneously distributed throughout the cannabis material particles.
36. The process of claim 35, wherein the permeation agent includes ethanol.
37. The process of claim 35 or 36, further comprising selecting an operating parameter for performing the superimposed revolution and rotation movements to purge the permeation agent and obtain the cannabis composition.
38. The process of claim 37, wherein the operating parameter is selected from one or more of a rotation speed, a revolution speed, an operation time, a maximal G force, and a ratio of revolution to rotation speeds.
39. The process of claim 37, wherein the operating parameter is selected from a predetermined set of operating parameters.
40. The process of claim 37, wherein the operation time is selected from the range of from about 10 seconds to about 15 minutes.
41. The process of claim 37, wherein the revolution speed is selected from the range of from 10 to about 4000 rpm.
42. A smokable product comprising a cannabis composition and a rolling medium containing the cannabis composition, wherein the cannabis composition includes cannabis material particles and a cannabis extract, wherein the cannabis extract is substantially homogeneously distributed throughout the cannabis material particles with the process of any one of claims 35 to 41 .