Compositions and methods for inhibiting the expression of microtubule-associated tau protein (mapt)

CL202601031A1Pending Publication Date: 2026-07-10SHANGHAI ARGO BIOPHARMACEUTICAL CO LTD

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Patent Information

Application Number: CL202601031
Authority / Receiving Office: CL · CL
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2024-10-11
Filing Date: 2026-04-01
Publication Date: 2026-07-10

Application Information

Patent Timeline

11 Oct 2024

Priority

01 Apr 2026

Application

CL202601031

10 Jul 2026

Publication

CL202601031A1

IPC: A61K48/00; C12N15/00; C12N15/09; C12N15/113; C12Q1/68; C12Q1/6883

CPC: C12N15/113; C07K14/4711; C12Q1/6883; C12Q2600/158; C12N2310/14; C12N2310/315; C12N2310/321; C12N2310/322

Inventors: SHU Dongxu; SHAO Pengcheng Patrick

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Abstract

Compositions and methods useful for reducing MAPT gene expression and for treating MAPT-associated diseases and conditions are provided. MAPT dsRNA agents, MAPT antisense polynucleotide agents, compositions comprising MAPT dsRNA agents, and compositions comprising MAPT antisense polynucleotide agents are provided for use in reducing MAPT expression in cells and subjects.

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