Anti-nectin-4 antibody conjugate drug comprising a camptothecin derivative.

CL202601225A1Pending Publication Date: 2026-07-31CELLTRION INC

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Patent Information

Application Number: CL202601225
Authority / Receiving Office: CL · CL
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2024-10-18
Filing Date: 2026-04-15
Publication Date: 2026-07-31

Application Information

Patent Timeline

18 Oct 2024

Priority

15 Apr 2026

Application

CL202601225

31 Jul 2026

Publication

CL202601225A1

IPC: A61K47/68; A61P35/00; C07K16/28

CPC: A61K47/68; A61P35/00; C07K16/2803; C07K2317/92; C07K2317/33; A61K47/68037; A61K47/6849; A61K47/6889

Inventors: SEO Jimin; KIM Jongin

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Abstract

The present invention provides an antibody-drug conjugate having a structure in which a compound according to Chemical Formula 1 or a pharmaceutically acceptable salt, stereoisomer, tautomer, prodrug, hydrate, solvate, or isotopically labeled analogue thereof is linked to an anti-nectin-4 antibody via a linker. The antibody-drug conjugate according to the present invention can selectively impart the effect of the compound of Chemical Formula 1 to cancer cells expressing nectin-4.

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