Peptidic acids as a glp1r agonist and antibody-drug conjugates thereof

Abstract

This document describes protein-drug conjugates and their compositions, useful, for example, for targeted action against the glucagon-like peptide-1 receptor (GLP-1R). In certain forms, peptidomimetic loads and bound loads are provided, along with methods for their manufacture. More specifically, GLP-1 peptidomimetics, antibody-drug conjugates, and compositions comprising anti-GLP-1R antibodies and GLP-1 peptidomimetic loads are provided, as well as methods for treating GLP-1R-associated conditions.