Methods
By increasing the activity or expression of LBD nitrogen-responsive transcription factors in tobacco plants, the production of nitrates and nitric oxide was regulated, thus solving the problem of tobacco-specific nitrosamine formation and achieving a significant reduction in TSNA content in tobacco products.
CN107208109BActive Publication Date: 2026-06-16BRITISH AMERICAN TOBACCO (INVESTMENTS) LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BRITISH AMERICAN TOBACCO (INVESTMENTS) LTD
- Filing Date
- 2016-02-04
- Publication Date
- 2026-06-16
Smart Images

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Abstract
The present invention provides a method for reducing at least one tobacco-specific nitrosamine or a precursor thereof in tobacco, comprising modifying a tobacco plant by increasing the activity and expression of a LBD (lateral organ boundary domain) nitrogen-responsive transcription factor. The present invention also provides a tobacco cell, a tobacco plant, a tobacco plant propagation material, a harvested leaf, a processed tobacco or a tobacco product obtainable according to the present invention.
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