固定化赖氨酸脱羧酶、其制备、1,5-戊二胺制备方法及产品
The immobilization method, which involves forming covalent bonds between an aldehyde-modified polymer carrier and lysine decarboxylase, solves the problems of low stability and reusability of immobilized lysine decarboxylase, enabling low-cost and high-efficiency production of 1,5-pentanediamine and promoting the industrialization of biological production.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- CATHAY BIOTECH INC
- Filing Date
- 2016-08-25
- Publication Date
- 2026-07-17
AI Technical Summary
In the existing technology, the stability and reusability of immobilized lysine decarboxylase are low, resulting in high production costs of 1,5-pentanediamine. In addition, the cost of carrier materials is high, and the immobilization method is complex, making it difficult to achieve industrial production.
An immobilization method using aldehyde-modified polymeric carriers to form covalent bonds with lysine decarboxylase was developed. Stable immobilized lysine decarboxylase was prepared by reacting low-cost polymeric materials such as cellulose and polyvinyl alcohol with aldehyde-modifying reagents. This immobilized lysine decarboxylase was used to catalyze the decarboxylation reaction of lysine to produce 1,5-pentanediamine.
It improves enzyme stability and reusability, reduces production costs, simplifies the preparation process of 1,5-pentanediamine, and promotes the industrialization of biological production.