GLP-1受体配体部分缀合的寡核苷酸及其用途

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By using compounds containing oligonucleotides and GLP-1 receptor ligand conjugates, the problem of targeting and regulating nucleic acid expression in GLP-1 receptor cells in existing technologies has been solved, achieving selective targeting and effective regulation of GLP-1 receptor cells, particularly significantly affecting nucleic acid expression in pancreatic β-islet cells.

CN109475568BActive Publication Date: 2026-07-17IONIS PHARMACEUTICALS INC +1

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Patent Information

Authority / Receiving Office: CN · China
Patent Type: Patents(China)
Current Assignee / Owner: IONIS PHARMACEUTICALS INC
Filing Date: 2017-05-04
Publication Date: 2026-07-17

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Abstract

本实施例提供了用于靶向表达GLP‑1受体的细胞的化合物和方法。

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