Control system for a biosafety cabinet detector

Abstract

The application provides a control system for a biosafety cabinet detector, comprising: a liquid feeding control unit capable of controlling a liquid feeding device to feed a liquid for detection to a liquid throwing device; a liquid throwing control unit capable of controlling the liquid throwing device to throw the liquid in a mist state to be sprayed on a working area of a biosafety cabinet to be detected; and the liquid feeding control unit is capable of setting and adjusting a feeding speed of the liquid feeding device according to a spraying speed of the liquid throwing device, so as to achieve the best experimental effect. The application also provides a corresponding biosafety cabinet detector and a biosafety cabinet detection method using the biosafety cabinet detector.

Description

Technical Field

[0001] This invention relates to a control system for a biosafety cabinet detector, and a biosafety cabinet detector having the control system. Background Technology

[0002] A biological safety cabinet (BSC) is designed to protect personnel, the laboratory environment, the external environment, and experimental samples from exposure to aerosols and splashes that may be generated during the operation or testing of infectious microorganisms.

[0003] Operator protection tests (OPTs) for biosafety cabinets can be performed using either the potassium iodide method or the microbiological method. The potassium iodide method, defined in the European biosafety cabinet standard EN12469:2000, is a test method for verifying the personnel protection capabilities of biosafety cabinets. This method utilizes a nozzle vortex disk to spray a uniform mist of potassium iodide microdroplets, simulating an aerosol, thereby measuring the contamination control performance of the biosafety cabinet.

[0004] Existing biosafety cabinet testing instruments using the potassium iodide method employ peristaltic pumps as the liquid delivery device. However, the speed of the peristaltic pump is not adjustable, and the nozzle vortex plate has limited speed settings, making precise adjustment impossible. Furthermore, existing biosafety cabinet testing instruments using the potassium iodide method operate in manual mode, allowing only continuous operation of a single functional module without the ability to set the running time. Frequent switching via buttons makes operation complex.

[0005] Since the speed of the peristaltic pump is usually not adjustable during actual testing, and the rotation speed of the disc of the slinging device can only be selected from a limited number of gears, the delivery speed of the peristaltic pump and the rotation speed of the disc of the slinging device may not match, thus failing to achieve the best atomization effect of potassium iodide liquid and affecting the experimental results. Summary of the Invention

[0006] The purpose of this invention is to provide a control system for a biosafety cabinet testing instrument that can conveniently, quickly and accurately detect the operator protection capability of a biosafety cabinet, as well as a biosafety cabinet testing instrument having the control system.

[0007] The technical solution of the present invention is as follows.

[0008] A first aspect of the present invention provides a control system for a biosafety cabinet detector, comprising:

[0009] The liquid delivery control unit controls the liquid delivery device to deliver the test liquid to the liquid-spinning device;

[0010] The liquid-spraying control unit is capable of controlling the liquid-spraying device to spray the liquid into a mist onto the working area of ​​the biosafety cabinet being tested;

[0011] The liquid delivery control unit can set and adjust the feed speed of the liquid delivery device according to the spraying speed of the liquid-throwing device.

[0012] Preferably, the liquid delivery device includes a peristaltic pump, and the liquid delivery control unit can control the feed of the peristaltic pump, thereby controlling the liquid flow rate.

[0013] Preferably, the liquid-spinning device includes a disk for atomizing the liquid and a motor for driving the disk to rotate; the liquid-spinning control unit can control the rotational speed of the motor and has a speed feedback device.

[0014] Preferably, the motor is a brushless DC motor, and the liquid-spinning control unit uses a PWM signal to control the brushless DC motor.

[0015] Preferably, the liquid-spinning control unit sets the rotation speed of the disk according to the density of the liquid.

[0016] Preferably, the control system further includes a negative pressure control unit, which can control the negative pressure generating device to form a negative pressure inside the biosafety cabinet, thereby collecting the mist-like liquid overflowing from outside the biosafety cabinet.

[0017] Preferably, the control system further includes a working mode control unit, which includes an interactive device that can be used to set the operating time and operating parameters of the liquid delivery device and the liquid slinging device during the experiment.

[0018] Preferably, the biosafety cabinet detector has two operating modes: manual mode and automatic mode.

[0019] In the automatic mode, the operating mode control unit can issue instructions according to the set experimental procedure to perform the detection of the biosafety cabinet.

[0020] A second aspect of the present invention provides a biosafety cabinet detector, including a liquid delivery device, a liquid dispensing device, and a control system for the biosafety cabinet detector according to any one of the above technical solutions.

[0021] A third aspect of the present invention provides a method for testing a biosafety cabinet using the biosafety cabinet detector described above, comprising the following steps:

[0022] Provide a biosafety cabinet testing instrument according to the above technical solution;

[0023] Start the liquid-spraying device and the negative pressure generating device. Set the spraying speed of the liquid-spraying device of the biosafety cabinet detector according to the measurement needs. At the same time, a negative pressure is formed inside the biosafety cabinet to collect the solution that has overflowed into the air.

[0024] Start the liquid delivery device and run it for a first length of time. Set the feed speed of the liquid delivery device according to the spraying speed of the liquid throwing device, and deliver a certain amount of liquid to the liquid throwing device at the feed speed.

[0025] The liquid delivery device is turned off after the liquid delivery is completed.

[0026] The negative pressure generating device stops operating after running for the second duration.

[0027] Collect and measure the experimental results.

[0028] Through the above technical solutions, the present invention can achieve the following technical effects.

[0029] (1) The built-in peristaltic pump of the peristaltic pump delivery device can deliver potassium iodide liquid crystal in the reagent bottle to the disc device through the silicone tube at a set feed rate and at a specified time.

[0030] (2) The disc-shaped liquid-throwing device can drive the disc to move through a high-speed DC brushless motor, and spray the liquid in the disc into a mist through the best centrifugal force in the working area to obtain the best atomization effect.

[0031] (3) The negative pressure generating device can draw negative pressure inside the biosafety cabinet by operating the negative pressure motor within a specified time period, thereby collecting the potassium iodide liquid that overflows from the air.

[0032] (4) The interactive device of the biosafety cabinet detector includes input and output devices such as a touch screen, which can monitor the working status and time of each device through the touch screen.

[0033] (5) The manual operation mode of the biosafety cabinet detector allows the operator to set the working time of each device through the touch screen and control the experimental process at any time.

[0034] (6) The automatic operation mode of the biosafety cabinet detector can perform the experimental process of the standard biosafety cabinet potassium iodide test method built into the equipment. The operator can start the process with one button to complete the entire experiment, and can also modify the parameter values ​​inside through the touch screen and save them. Attached Figure Description

[0035] Figure 1 This is a schematic diagram illustrating the principle of the potassium iodide test for the protective capabilities of biosafety cabinet operators.

[0036] Figure 2This is a schematic diagram of the control system structure of the biosafety cabinet detector of the present invention. Detailed Implementation

[0037] As attached Figure 1 The diagram illustrates the principle of using the potassium iodide test to measure the operator protection capability of a biosafety cabinet. During the test, the negative pressure motor and the disc (nozzle vortex disc) are first started to achieve a stable rotational speed. Then, a peristaltic pump is started and runs for a specified time, delivering a certain amount of potassium iodide liquid to the nozzle vortex disc at a specific feed rate. After delivery, the peristaltic pump is turned off. The negative pressure motor stops running after the specified time, and the filter membrane is removed from the sampler. The number of potassium iodide particles adhering to the filter membrane is measured, and the caliber protection parameter (A) of the biosafety cabinet is calculated. pf ).

[0038] Example 1

[0039] The first embodiment of the present invention provides a control system for a biosafety cabinet detector, comprising:

[0040] The liquid delivery control unit controls the liquid delivery device to deliver the test liquid to the liquid-spinning device;

[0041] The liquid-spraying control unit is capable of controlling the liquid-spraying device to spray the liquid into a mist onto the working area of ​​the biosafety cabinet being tested;

[0042] The liquid delivery control unit can set and adjust the feed speed of the liquid delivery device according to the spraying speed of the liquid-throwing device.

[0043] In a preferred embodiment, the liquid delivery device includes a peristaltic pump, and the liquid delivery control unit is capable of controlling the feed of the peristaltic pump, thereby controlling the liquid flow rate.

[0044] In a preferred embodiment, the liquid-spinning device includes a disk for atomizing the liquid and a motor for driving the disk to rotate; the liquid-spinning control unit is capable of controlling the rotational speed of the motor and has a speed feedback device.

[0045] In a preferred embodiment, the motor is a brushless DC motor, and the liquid-spinning control unit uses a PWM signal to control the brushless DC motor.

[0046] In a more preferred embodiment, a PWM signal is used to control the brushless DC motor, enabling 200 speed increments and providing speed feedback to reflect the motor's speed in real time. Those skilled in the art will understand that the speed feedback for the brushless DC motor should have sufficient accuracy to meet the control requirements of the liquid-spinning control unit. Speed ​​feedback can be achieved using any applicable method prior to this in the art.

[0047] In a preferred embodiment, the liquid-spinning control unit sets the rotation speed of the disk according to the density of the liquid.

[0048] In a preferred embodiment, the control system further includes a negative pressure control unit, which can control the negative pressure generating device to create a negative pressure inside the biosafety cabinet, thereby collecting the mist-like liquid overflowing from outside the biosafety cabinet.

[0049] In a preferred embodiment, the control system further includes a working mode control unit, which includes an interactive device that can be used to set the operating time and operating parameters of the liquid delivery device and the liquid spitting device during the experiment.

[0050] In a preferred embodiment, the biosafety cabinet detector has two operating modes: manual mode and automatic mode.

[0051] In the manual mode, the peristaltic pump and DC motor timings can be customized. Once defined, the system will run according to the program logic of the automatic mode.

[0052] In the automatic mode, the operating mode control unit can issue instructions according to the set experimental procedure to perform the detection of the biosafety cabinet.

[0053] Example 2

[0054] A second embodiment of the present invention provides a biosafety cabinet detector, including a liquid delivery device, a liquid ejection device, a negative pressure generating device, and a control system for a biosafety cabinet detector according to any one of the first embodiments.

[0055] Those skilled in the art will understand that the liquid delivery control unit and the liquid slinging control unit in the first embodiment are not necessarily independent hardware units, but can be jointly implemented by a programmed main control module, such as... Figure 2 As shown.

[0056] The liquid delivery device has a built-in peristaltic pump that delivers a certain amount of potassium iodide liquid from the reagent bottle to the disc of the liquid-splitting device through a silicone tube. The motor of the peristaltic pump is electrically connected to the main control module, so its feed speed can be controlled by the main control module.

[0057] The liquid-spraying device uses a disc motor to drive a disc, which then uses centrifugal force to atomize the liquid within the disc and spray it into the working area. The disc motor is electrically connected to the main control module, allowing its rotation speed to be controlled by the main control module. In a preferred embodiment, the disc motor is a high-speed brushless DC motor.

[0058] The negative pressure generating device uses a negative pressure motor to create negative pressure inside the machine housing to collect potassium iodide liquid that has leaked out of the air. The negative pressure motor is electrically connected to the main control module, so its operating parameters can also be controlled by the main control module.

[0059] The interactive device includes a touchscreen display module with a button display section. The touchscreen display module is electrically connected to the main control module, thereby enabling monitoring of the device's operating status and time. In a preferred embodiment, the touchscreen is a 5-inch touchscreen.

[0060] In an alternative embodiment, the interactive device may also include a mechanical switch in the form of a knob or slider for adjusting the speed of the peristaltic pump motor, the disc motor, and / or the negative pressure motor.

[0061] The biosafety cabinet testing instrument has both manual and automatic operation modes.

[0062] In manual operation mode, the operator can set the working time of each device through the display screen to control the experimental process at any time.

[0063] In automatic operation mode, the biosafety cabinet tester can perform the experimental process of the built-in standard biosafety cabinet potassium iodide test method. The operator can start the process with one button to complete the entire experiment, or modify and save the parameter values ​​through the touch screen.

[0064] Example 3

[0065] The third embodiment of the present invention provides a method for testing a biosafety cabinet using the biosafety cabinet testing instrument of the present invention.

[0066] When the biosafety cabinet is in manual operation mode, the method for detecting the biosafety cabinet includes the following steps:

[0067] Provide a biosafety cabinet testing instrument according to the above technical solution;

[0068] Start the liquid-spraying device and set the spraying speed of the liquid-spraying device of the biosafety cabinet detector according to the density of the liquid used;

[0069] Activate the negative pressure generating device to create negative pressure inside the biosafety cabinet, thereby collecting the solution that has overflowed from the biosafety cabinet;

[0070] Start the liquid delivery device and run it for a first length of time. Set the feed speed of the liquid delivery device according to the spraying speed of the liquid-throwing device, and deliver a certain amount of liquid to the liquid-throwing device.

[0071] After the negative pressure generating device has been running for a second period of time, the collection and measurement of experimental results are stopped.

[0072] Those skilled in the art will understand that during the initial period of operation of the liquid delivery device, the liquid delivery device should be able to deliver a predetermined amount of liquid to the liquid-splitting device at a set feed rate. Furthermore, during the operation of the liquid delivery device, the rotational speed of the disc in the liquid-splitting device should remain stable at a predetermined value.

[0073] Those skilled in the art will understand that during the second length of operation of the negative pressure generating device, the negative pressure generating device should fully collect the overflowing liquid during the operation of the liquid-spinning device, thereby improving the accuracy of the measurement results.

[0074] When the biosafety cabinet is in automatic operation mode, the method for detecting the biosafety cabinet includes the following steps.

[0075] Provide a biosafety cabinet testing instrument according to the above technical solution;

[0076] Set and save the parameter values ​​for the experiment.

[0077] Initiate the built-in experimental process of the biosafety cabinet detector, which includes:

[0078] Start the liquid-spraying device and the negative pressure generating device, and set the spraying speed of the liquid-spraying device of the biosafety cabinet detector according to the measurement needs. At the same time, a negative pressure is formed inside the biosafety cabinet to collect the solution that overflows from the biosafety cabinet.

[0079] Start the liquid delivery device and run it for a first length of time. Set the feed speed of the liquid delivery device according to the spraying speed of the liquid throwing device, and deliver a certain amount of liquid to the liquid throwing device at the feed speed.

[0080] The liquid delivery device is turned off after the liquid delivery is completed.

[0081] The negative pressure generating device stops operating after running for the second duration.

[0082] Collect and measure the experimental results.

Claims

1. A biosafety cabinet detector, characterized in that, The biosafety cabinet detector is used for detecting the caliber protection parameter A of the biosafety cabinet by using the potassium iodide method pf , comprising a liquid feeding device, a liquid throwing device, a negative pressure generating device, and a control system. The control system includes: The liquid delivery control unit is capable of controlling the liquid delivery device to deliver the potassium iodide liquid for testing to the liquid slinging device, and is capable of setting and adjusting the feed speed of the liquid delivery device according to the spraying speed of the liquid slinging device. The liquid spraying control unit is capable of controlling the liquid spraying device to spray the potassium iodide liquid into a mist onto the working area of ​​the biosafety cabinet being tested. The negative pressure control unit can control the negative pressure generating device to create negative pressure inside the biosafety cabinet detector, thereby collecting the mist-like liquid overflowing from outside the biosafety cabinet. The working mode control unit includes an interactive device that can be used to set the operating time and operating parameters of the liquid delivery device and the liquid spitting device during the experiment; The liquid delivery device includes a peristaltic pump, and the liquid delivery control unit can control the feed of the peristaltic pump, thereby controlling the liquid flow rate; The liquid-spraying device includes a disc for atomizing the liquid and a motor for driving the disc to rotate; the liquid-spraying device drives the disc to move through the motor, and sprays the liquid in the disc into a mist through centrifugal force into the working area of ​​the biosafety cabinet being tested. The liquid-spinning control unit can control the speed of the motor and has a speed feedback device, so as to spin the liquid in the disc into a mist and spray it into the working area through the best centrifugal force to obtain the best atomization effect. The biosafety cabinet detector has two operating modes: manual and automatic. In the automatic mode, the working mode control unit is capable of issuing instructions according to a set experiment process, thereby performing detection on the biosafety cabinet, calculating the aperture protection parameter A of the biosafety cabinet pf ; In the manual mode, the peristaltic pump and DC motor timings are first set custom-defined. Once defined, the system will run according to the automatic mode's program logic, thereby performing tests on the biosafety cabinet and calculating the biosafety cabinet's caliber protection parameter A. pf .

2. The biosafety cabinet detector according to claim 1, characterized in that, The motor is a brushless DC motor, and the liquid-spinning control unit uses a PWM signal to control the brushless DC motor.

3. The biosafety cabinet detector according to claim 1, characterized in that, The liquid-spinning control unit sets the rotation speed of the disk according to the density of the liquid.

4. A method for detecting a biosafety cabinet using the potassium iodide method with the biosafety cabinet detector according to any one of claims 1-3, comprising the following steps: Provide a biosafety cabinet detector according to any one of claims 1-3; Start the liquid-spraying device and the negative pressure generating device, and set the spraying speed of the liquid-spraying device of the biosafety cabinet detector according to the measurement needs. At the same time, a negative pressure is formed inside the biosafety cabinet to collect the solution that overflows from the biosafety cabinet. Start the liquid delivery device and run it for a first length of time. Set the feed speed of the liquid delivery device according to the spraying speed of the liquid throwing device, and deliver a certain amount of liquid to the liquid throwing device at the feed speed. The liquid delivery device is turned off after the liquid delivery is completed. The negative pressure generating device stops operating after running for the second duration. Collect and measure the experimental results.

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