Imidazoloquinoline substituted phosphate agonist and its preparation method and application

CN112778372BActive Publication Date: 2025-09-23SUZHOU ZELGEN BIOPHARML +1
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Patent Information

Application Number
CN201911097066.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2019-11-11
Publication Date
2025-09-23
Estimated Expiration
2039-11-11

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Abstract

The present invention relates to imidazoquinoline-substituted phosphate agonists, their preparation methods, and uses. Specifically, the compounds of the present invention have the structure represented by formula (I), wherein the definitions of the various groups and substituents are as described in the specification. The present invention also discloses methods for preparing the compounds and their use as TLR agonists.
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Citation Information

Patent Citations

  • Esterified imidazoquinoline derivatives

    CN102264394A

  • PEGylated imidazoquinolines as TLR7 and TLR8 agonists

    CN108368140A