A vascular stent

Abstract

The present application discloses a kind of vascular stents, characterized by stent has self-cleaning effect, not only in the stent around secondary embolism, stenosis is not easy to form, but also can change the direction of hemodynamics, make the slowdown of intravascular sedimentation, while can delay the speed of arteriosclerosis.The present application can be used for coronary artery stenosis embolism and coronary artery rehabilitation, other parts of arteriosclerosis embolism and rehabilitation, not easy to cause the risk of secondary operation.The present application also has the characteristics of low cost, significant economic benefits and the like.

Description

Technical Field

[0001] This invention belongs to the medical field and relates to a device for cardiac rehabilitation and improving arterial blood flow supply. Background Technology

[0002] Whether it's peripheral vascular disease or cardiovascular and cerebrovascular disease, there are currently three main categories of treatment methods: traditional conservative drug treatment, traditional surgical treatment, and interventional techniques under fluoroscopic guidance. Drug treatment is often suitable for milder cases where the patient's basic condition is poor and they cannot tolerate surgery. Its treatment cycle is relatively long, its effects are slow, it has certain side effects, and it can even lead to drug dependence. Traditional surgical treatment causes significant harm to the patient's body due to the trauma of the procedure. Moreover, the current cardiovascular disease population is mainly the elderly, and their postoperative recovery is relatively slower compared to younger people. Therefore, interventional therapy, as a minimally invasive treatment with less surgical trauma and better efficacy, has undoubtedly become the preferred treatment for most arterial diseases. During interventional surgery, under image monitoring, a guidewire is inserted through a small-diameter artery in the body to reach the target blood vessel. Contrast agent is injected first, and the blood vessel is visualized under X-ray, allowing the vessel diameter to be measured to select an appropriately sized stent and balloon.

[0003] Vascular stents have evolved from the first generation to the third generation. The first generation of vascular stents were bare-metal stents, which could temporarily resolve vascular stenosis after implantation, but over time they were prone to thrombosis, causing restenosis. Therefore, the second generation of vascular stents emerged. The second generation of vascular stents were drug-eluting stents, which slowly release anticoagulants through a drug layer, delaying thrombus reformation and reducing the thrombus reformation rate by up to 80%. This was once considered a major invention in medical history, bringing good news to cardiovascular patients. However, this manufacturing technology was monopolized by Johnson & Johnson and Boston Scientific. In fact, the drug coating is not a permanent solution; once the drug on the stent is released, thrombi can still form again, causing vascular embolism. Therefore, research into third-generation vascular stents began. On the one hand, people rely on biotechnology to coat the surface of stents with stem cells, also known as cell-coated stents, to form a vascular membrane on the stent. However, there is still a risk of restenosis. Therefore, we conducted hemodynamic research to enable vascular stents to have self-cleaning functions. We know that vascular stents are like dams. If there is no thrombus in front of the dam, it is easy for stasis to form behind the dam, causing restenosis. We adopted the dual diversion principle to overcome the problem of thrombus formation leading to vascular stenosis. Summary of the Invention

[0004] We achieved the purpose of this invention through numerous repeated experiments.

[0005] Further explanation is as follows: A type of vascular stent is characterized by having two guide strips configured on a two-stage annular stent, which causes blood fluid to rotate and continuously flush the stent and guide strips, thus eliminating the phenomenon of "siltation after the dam".

[0006] The vascular stent is characterized by having spherical structures at both ends of the guide strip to prevent the risk of puncturing blood vessels.

[0007] The vascular stent is characterized by a foldable structure, which allows it to automatically unfold when X-rays are guided to the stenotic placement site and the folding traction wire is released.

[0008] The vascular stent is characterized by using biocompatible materials, which are less likely to cause "foreign body inflammation" and complications.

[0009] The vascular stent is characterized by employing sustained-release technology, continuously releasing anticoagulant drugs from its surface to prevent thrombus formation and restenosis.

[0010] The foldable structure described herein is designed to fold laterally to reduce its size while maintaining its longitudinal dimensions, thus facilitating interventional procedures.

[0011] The biocompatible material comprises rigid materials such as alloys, ceramics, and polycarbonate plastics, as well as compatibility coating materials, including starch polymers, chitosan, polylactic acid (PLA), and polyethylene glycol (PEG).

[0012] The anticoagulant drugs mentioned include those that have been discovered and those that will be discovered in the future, namely warfarin, heparin sodium, small molecule dextran, and snake blood anticoagulant. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of a vascular stent, where 1 is the anterior support ring, 2 is the folding groove buckle, 3 is the folding groove, 4 is the guide strip, 5 is the lower support ring folding groove, 6 is the posterior support ring, and 7 is the lower support ring folding groove.

[0014] Figure 2 This is an axonometric view of a vascular stent, reflecting the overall structure of the stent.

[0015] When blood enters from one end and acts on the blood vessel wall, the swirling flow generated by the guide strip prevents easily deposited low-density protein particles, platelets, and other solid particles from remaining there. This utilizes the self-cleaning properties of the blood flow to overcome the risk of embolism inherent in previous generations of stents. The technical solution of this invention is further illustrated below through examples. Detailed Implementation

[0016] Example 1 We placed the stent prepared according to this invention and the second-generation stent into the coronary blood vessels of four dogs, respectively, and interchanged their positions. A comparative experiment was conducted for 720 days. The stents and the blood vessels surrounding the stents were then removed and observed under a microscope. The changes on the surface of the third-generation stent and around the blood vessels were significantly better than those of the second-generation stent.

[0017] Example 2 When beagles with second- and third-generation vascular stents were placed and kept for six months, one year, two years, and five years, the stent placement sites were dissected. It was found that the risk of re-blockage of the third-generation stent was lower. Although hyperplasia occurred at the stent placement sites, the third-generation stent created swirl channels, which reduced the risk of secondary embolism and coronary atherosclerosis.

[0018] The above descriptions are merely some embodiments of the present invention. Those skilled in the art can make various modifications and improvements without departing from the inventive concept of the present invention, and these all fall within the scope of protection of the present invention.

Claims

1. A vascular stent, characterized in that, It includes a coaxial core wire with corresponding upper and lower folding grooves and connected front and rear support rings. There are two guide strips on the inner wall of the front and rear support ring brackets, which cause the blood fluid to rotate and continuously flush the bracket and guide strips, so that there is no "siltation after the dam" phenomenon; the front and rear support rings form a foldable structure.

2. The vascular stent as described in claim 1, characterized in that, Both ends of the guide strip have a spherical structure to prevent snagging or rupturing blood vessels.

3. The vascular stent as described in claim 1, characterized in that, The foldable structure folds down to a smaller size while maintaining its longitudinal dimensions. It expands on its own to open the stent, facilitating interventional surgery.

4. The vascular stent as described in claim 1, characterized in that, Biocompatible materials were used.

5. The vascular stent as described in claim 1, characterized in that, It employs sustained-release technology to continuously release anticoagulant drugs, preventing thrombosis and restenosis of blood vessels.

6. The biocompatible material as described in claim 4, wherein the rigid material includes alloys, ceramics, and polycarbonate plastics, and the coating material includes starch polymers, chitosan, polylactic acid (PLA), and polyethylene glycol (PEG).

7. The vascular stent as described in claim 5, characterized in that... The anticoagulant drugs include warfarin, heparin sodium, small molecule dextran, and snake blood anticoagulant enzyme, which are continuously released through the sustained-release technology.

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