Chromosome band image enhancement method and system, intelligent terminal and storage medium

By performing convolution processing, threshold extraction and grayscale mapping on chromosome images, combined with sharpening processing, the problems of chromosome images blurring and streak quality floating are solved, and the clarity and analysis efficiency of the image are significantly improved.

CN114155162BActive Publication Date: 2025-04-04HUNAN ZIXING INTELLIGENT MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202111345047.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-11-15
Publication Date
2025-04-04
Estimated Expiration
2041-11-15

AI Technical Summary

Technical Problem

In modern human chromosome karyotyping analysis, there is a problem of chromosome images, which leads to increased difficulty in karyotyping analysis, and the streak mass after chromosome imaging fluctuates greatly, affecting the accuracy of karyotyping analysis.

Method used

A chromosomal streak image enhancement method is used to process the initial chromosomal images through convolution operators and threshold methods, extract deep streak areas and shallow streak areas, generate chromosomal grayscale mapping tables, and perform sharpening processing to enhance the sharpness and characteristic significance of the image.

Benefits of technology

The clarity of chromosomal images is significantly improved, making the main streaks obvious, and the transition between the sub-deep streaks and shallow streaks obvious, retaining the details of streaks, improving the efficiency of karyotype analysis, and solving the problem of large floating image quality.

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Abstract

The present invention discloses a method and system for enhancing a chromosome banding image, an intelligent terminal and a storage medium. The method comprises obtaining an initial chromosome image; obtaining a chromosome convolution image; obtaining a chromosome deep banding region image Img3; obtaining a deep banding gray value gray1 and a shallow banding gray value gray2; obtaining a chromosome grayscale mapping table; obtaining a chromosome grayscale mapping image Img4; and obtaining a chromosome enhanced image Img5. The present invention performs banding enhancement and sharpening processing, so that the main banding of the chromosome in the processed image is obvious, the main features of each type of chromosome are highlighted, the transition between the secondary deep banding and the shallow banding is obvious, so that the details of the chromosome banding are not lost, and sharpening is performed, so that the chromosome image becomes clearer, the chromosome image banding is clearly expressed, the features are prominent, the image is easy to analyze, the work efficiency is improved, and the problem of large fluctuation of chromosome image quality caused by chromosome staining technology and imaging hardware is solved.
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Citation Information

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