Antibodies against and kits for detecting anti-mullerian hormone

CN114478765BActive Publication Date: 2026-07-07DONGGUAN PENGZHI BIOTECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
DONGGUAN PENGZHI BIOTECH CO LTD
Filing Date
2020-11-12
Publication Date
2026-07-07

AI Technical Summary

Technical Problem

Existing methods for detecting anti-Müllerian hormones suffer from problems such as long processing time, low sensitivity, high false positive and false negative rates, high cost, and unsuitability for small-batch testing. Furthermore, there are few monoclonal antibody products for anti-Müllerian hormones, and their performance varies.

Method used

An antibody against Müllerian duct hormone is provided, having a complementary determinant region structure that specifically binds to the anti-Müllerian duct hormone, including CDR-VH1, CDR-VH2, CDR-VH3, CDR-VL1, CDR-VL2 and CDR-VL3, which binds to a specific marker for detection. The preparation method includes recombinant genetics technology and an automated peptide synthesizer.

Benefits of technology

It achieves highly sensitive and specific detection of anti-Müllerian hormones, provides better antibody selection, is suitable for small-batch testing, reduces costs, and improves detection efficiency and accuracy.

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Abstract

The application discloses an antibody against anti-Mullerian hormone and a kit for detecting anti-Mullerian hormone, and relates to the technical field of antibodies.The antibody against anti-Mullerian hormone disclosed by the application comprises a heavy chain complementarity determining region and a light chain complementarity determining region.The antibody has good affinity to anti-Mullerian hormone antigen, and the use of the antibody for detecting anti-Mullerian hormone has good sensitivity and specificity.The application provides more antibody options for detecting anti-Mullerian hormone, and the performance of the antibody is better.
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