biochemical analyzer

Abstract

This invention relates to the field of biochemical analysis equipment and discloses a biochemical analyzer. The biochemical analyzer includes a cleaning system comprising at least one first cleaning section, at least one suction section, and at least one first wiping section. The first wiping section and the suction section are independently arranged, with the suction section positioned between the first cleaning section and the first wiping section along the rotation direction of the reaction disk. The distance between the suction section and the nearest first wiping section in the rotation direction of the reaction disk is an integer multiple of the distance the reaction vessel travels in one rotation cycle of the reaction disk, and less than the distance the reaction vessel travels in one progressive cycle of the reaction disk. This invention achieves suction and wiping treatments after liquid injection cleaning of the reaction vessel without increasing the number of reaction vessels required on the reaction disk or increasing the progressive cycle, thus ensuring that the installation of the suction section does not reduce the efficiency of the reaction vessel.

Description

Technical Field

[0001] This invention relates to the field of biochemical analysis equipment, and more particularly to a biochemical analyzer. Background Technology

[0002] When a biochemical analyzer is in operation, reagents and samples need to be added to a reaction vessel for reaction and the results tested. The reaction vessel is a reusable device; after each test, it is cleaned and reused. The cleaning process involves injecting cleaning solution into the reaction vessel, followed by emptying the solution after cleaning. This process requires strict control over the amount of liquid remaining in the reaction vessel after cleaning, and the consistency of this residual amount each time. If the residual amount is large, or if there is inconsistent residue, the sample solution will be diluted when the reaction vessel is reused, potentially leading to unstable test results.

[0003] To solve the above-mentioned technical problems, the existing technology employs the following technical solution:

[0004] A single cleaning device is equipped with an injection cleaning needle, a suction needle, and a swab. These three components are driven to move up and down synchronously via a common lifting mechanism. The cleaning method in this scheme is as follows: the reaction vessel is cleaned multiple times using the injection cleaning needle; after the final injection cleaning, in the next progressive cycle, the reaction vessel moves to the suction needle position, where the liquid is suctioned away to achieve vacuuming; in the following progressive cycle, the reaction vessel moves to the swab position, where it is wiped clean.

[0005] The above technical solutions still have the following shortcomings in practical applications:

[0006] Due to the requirements of the water blank test for the reaction vessel, a progressive cycle needs to be reserved between the last stage liquid injection cleaning needle and the suction needle for the water blank test. Therefore, the setting of the suction needle will increase the number of reaction vessels required for the reaction plate (under the condition of a certain measurement position, increasing the number of needle positions in the cleaning system requires a corresponding increase in the number of reaction vessels, otherwise it will lead to changes in the system reaction time and measurement cycle, and ultimately lead to abnormal test results) and add a progressive cycle, which will increase the rotation cycle of the reaction plate required for cleaning a single reaction vessel, thereby increasing the manufacturing difficulty of the reaction vessel and reducing the utilization efficiency of the reaction vessel. Summary of the Invention

[0007] The first objective of this invention is to provide a biochemical analyzer that addresses the technical problem of low efficiency in reaction vessels caused by the cavitation process in existing biochemical analyzers requiring an independent progressive cycle.

[0008] To achieve the above objectives, the present invention provides a biochemical analyzer, comprising a reaction plate, a rotary drive device, a sample dispensing device, a reagent dispensing device, a stirring device, a detection device, and a cleaning system.

[0009] The reaction disk has multiple accommodating slots distributed circumferentially for placing reaction containers, and the reaction disk has a rotation cycle and a progressive cycle. The rotation cycle is the reaction disk completing one rotation and one stop action; the progressive cycle includes at least two of the rotation cycles, and the distance that the reaction container moves circumferentially relative to the reaction disk after one progressive cycle is equal to the distance between two adjacent reaction containers on the circumferential direction of the reaction disk.

[0010] The rotary drive device is used to drive the reaction disk to rotate.

[0011] The cleaning system, the sample dispensing device, the reagent dispensing device, the stirring device, and the detection device are distributed along the circumference of the reaction plate;

[0012] The cleaning system includes:

[0013] At least one first cleaning unit, the first cleaning unit being used to perform liquid injection cleaning on the reaction vessel on the reaction plate;

[0014] At least one suction section is provided, which is used to suction the liquid remaining in the reaction vessel after it has been cleaned by the first cleaning section.

[0015] At least one first wiping section, the first wiping section and the suction section are independently arranged, and the first wiping section is used to wipe the liquid remaining in the reaction vessel after the liquid is sucked by the suction section;

[0016] During the process of the reaction disk driving the reaction vessel to rotate from one first cleaning section to one progressive cycle, the suction part is located between the first cleaning section and the first wiping part along the rotation direction of the reaction disk; and the distance between the suction part and the first wiping part closest to the first cleaning section in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction vessel moves in one rotation cycle of the reaction disk, and less than the distance the reaction vessel moves in one progressive cycle of the reaction disk, where the integer multiple is a value greater than or equal to one;

[0017] The detection device is used to perform water blank detection on the reaction vessel after it has been cleaned by the first cleaning section and before the liquid is drawn off by the vacuum section.

[0018] The second objective of this invention is to provide a biochemical analyzer, comprising a reaction plate, a rotary drive device, a sample dispensing device, a reagent dispensing device, a stirring device, a detection device, and a cleaning system;

[0019] The reaction disk has multiple accommodating slots distributed circumferentially for placing reaction containers, and the reaction disk has a rotation cycle and a progressive cycle. The rotation cycle is the reaction disk completing one rotation and one stop action; the progressive cycle includes at least two of the rotation cycles, and the distance that the reaction container moves circumferentially relative to the reaction disk after one progressive cycle is equal to the distance between two adjacent reaction containers on the circumferential direction of the reaction disk.

[0020] The rotary drive device is used to drive the reaction disk to rotate.

[0021] The cleaning system, the sample dispensing device, the reagent dispensing device, the stirring device, and the detection device are distributed along the circumference of the reaction plate;

[0022] The cleaning system includes:

[0023] At least one first cleaning unit, the first cleaning unit being used to perform liquid injection cleaning on the reaction vessel on the reaction plate;

[0024] An idle position is provided for the cleaning system to clean the reaction vessel after it has been cleaned by the first cleaning section. The distance between the idle position and the nearest first cleaning section is equal to the distance the reaction vessel moves circumferentially relative to the reaction plate during one progressive cycle.

[0025] At least one suction section is provided for suctioning the liquid remaining in the reaction vessel after it has been cleaned by the first cleaning section and passed through the idle position.

[0026] The detection device is used to perform water blank detection on the reaction vessel after it has been cleaned by the first cleaning section and passed through the idle position before the liquid is drawn in the suction section.

[0027] During the process of the reaction disk driving the reaction vessel to rotate from the idle position to one progressive cycle, the first cleaning part is located between the idle position and the suction part along the rotation direction of the reaction disk, and the distance between the idle position and the suction part in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction vessel moves in one rotation cycle of the reaction disk, and less than the distance the reaction vessel moves in one progressive cycle of the reaction disk, where the integer multiple is a value greater than or equal to one.

[0028] The biochemical analyzer provided by this invention has an independent suction section and a first wiping section. After the first cleaning section completes the liquid injection cleaning of the reaction container and the detection device completes the water blank detection of the reaction container, the suction section can first perform liquid suction treatment on the reaction container, and then the first wiping section can wipe the reaction container after the suction treatment. This can greatly reduce the amount of liquid residue in the reaction container and effectively ensure the stability of the test results of the biochemical analyzer. Furthermore, this invention positions the vacuum suction unit between the first cleaning unit and the first wiping unit along the rotation direction of the reaction disk; and designs the distance between one vacuum suction unit and one first wiping unit in the rotation direction of the reaction disk to be an integer multiple of the distance the reaction container travels in one rotation cycle of the reaction disk, and less than the distance the reaction container travels in one progressive cycle of the reaction disk. In this way, the vacuum suction operation of a reaction container and the water blank detection or wiping operation of the reaction container can be performed in different rotation cycles of the same progressive cycle. This allows the vacuum suction treatment of the reaction container by the vacuum suction unit to not occupy an independent progressive cycle. Thus, without increasing the number of reaction containers required on the reaction disk or increasing the progressive cycle and cleaning time, the vacuum suction treatment and wiping treatment of the reaction container after liquid injection and cleaning can be performed sequentially. Ultimately, the setting of the vacuum suction unit will not reduce the utilization efficiency of the reaction container. Attached Figure Description

[0029] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0030] Figure 1 This is a schematic diagram showing the distribution of the cleaning system, reaction plate, and reaction vessel provided in Embodiment 1 of the present invention;

[0031] Figure 2 yes Figure 1 A magnified view of a portion of point A in the middle;

[0032] Figure 3 yes Figure 1 A magnified view of a portion of point B in the middle;

[0033] Figure 4 This is a schematic diagram of the cleaning system provided in Embodiment 1 of the present invention;

[0034] Figure 5 This is a schematic diagram of the composition of the biochemical analyzer provided in Embodiment 1 of the present invention;

[0035] Figure 6 This is a schematic diagram of the control method for the biochemical analyzer provided in Embodiment 1 of the present invention;

[0036] Figure 7 This is a schematic diagram of the air suction device provided in Embodiment 2 of the present invention;

[0037] Figure 8 This is a schematic diagram of the control method for the biochemical analyzer provided in Embodiment 2 of the present invention;

[0038] Figure 9 This is a schematic diagram of the air suction device provided in Embodiment 3 of the present invention;

[0039] Figure 10 This is a schematic diagram of the wiping device provided in Embodiment 5 of the present invention;

[0040] Figure 11 This is a schematic diagram showing the distribution of the suction section and the second cleaning section provided in Embodiment Six of the present invention;

[0041] Figure 12 This is a schematic diagram of the air suction device provided in Embodiment 7 of the present invention.

[0042] Explanation of icon numbers:

[0043] 100. Cleaning system; 110. First cleaning device; 111. First lifting drive mechanism; 112. First cleaning section; 1121. First cleaning agent cleaning section; 1101. First liquid suction section; 1102. First liquid injection section; 1122. First clean water cleaning section; 1103. Third liquid suction section; 1104. Third liquid injection section; 113. First wiping section; 114. Idle position; 120. Vacuum suction device; 121. Second lifting drive mechanism; 122. Vacuum suction section; 123. Second wiping section; 124. Second cleaning section; 1241. Second liquid suction section; 1242. Second liquid injection section; 130. Second wiping device; 131. Fourth lifting drive mechanism; 132. Third Wiping unit; 200, reaction plate; 210, container; 211, first container; 212, second container; 300, reaction vessel; 400, sample dispensing device; 500, reagent dispensing device; 510, first reagent dispensing mechanism; 520, second reagent dispensing mechanism; 600, stirring device; 610, first stirring mechanism; 620, second stirring mechanism; 700, detection device; S10, first cleaning step; S11, cleaning agent cleaning step; S12, clean water cleaning step; S20, water blank detection step; S30, vacuum step; S40, wiping step; S41, first wiping step; S42, third wiping step; S43, second wiping step. Detailed Implementation

[0044] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0045] It should be noted that all directional indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present invention are only used to explain the relative positional relationship and movement of each component in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly.

[0046] It should also be noted that when a component is referred to as being "fixed to" or "set on" another component, it can be directly on the other component or may be connected to an intermediary component. When a component is referred to as being "connected to" another component, it can be directly connected to the other component or indirectly connected to the other component through an intermediary component.

[0047] Furthermore, the use of terms such as "first" and "second" in this invention is for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. Additionally, the technical solutions of the various embodiments can be combined with each other, but only on the basis of being achievable by those skilled in the art. When the combination of technical solutions is contradictory or impossible to implement, such a combination of technical solutions should be considered non-existent and not within the scope of protection claimed by this invention.

[0048] Example 1:

[0049] like Figure 1-6 As shown, the cleaning system 100 provided in Embodiment 1 of the present invention is used to clean the reaction container 300 on the reaction plate 200 of a biochemical analyzer. The cleaning system 100 includes a first cleaning device 110 and a vacuum device 120. The first cleaning device 110 includes at least one first cleaning section 112, which is used to inject liquid into the reaction container 300 on the reaction plate 200 for cleaning. The vacuum device 120 includes at least one vacuum section 122, which is used to suction out the residual liquid in the reaction container 300 after cleaning by the first cleaning section 112. In this embodiment, after the first cleaning section 112 completes the liquid injection cleaning of the reaction container 300, the independent vacuum section 122 performs liquid suction treatment on the reaction container 300, thereby greatly reducing the amount of residual liquid in the reaction container 300 and effectively ensuring the stability of the biochemical analyzer test results.

[0050] In one embodiment, the cleaning system 100 further includes a first wiping device, which includes at least one first wiping section 113. The first wiping section 113 and the suction section 122 are independently arranged, and the first wiping section 113 is used to wipe the liquid remaining in the reaction container 300 after the suction section 122 has absorbed the liquid. In this embodiment, after the first cleaning section 112 completes the liquid injection cleaning of the reaction container 300, the independent suction section 122 and the first wiping section 113 sequentially perform liquid absorption and wiping treatment on the reaction container 300, thereby greatly reducing the amount of liquid residue in the reaction container 300 and effectively ensuring the stability of the biochemical analyzer test results.

[0051] In this embodiment, the reaction disk 200 has a rotation cycle and a progressive cycle. The rotation cycle is the process of the reaction disk 200 completing one rotation and one stop. The progressive cycle includes at least two rotation cycles. When the reaction disk 200 is fully loaded with reaction containers 300, the distance that the reaction containers 300 move relative to the reaction disk 200 in the circumferential direction after one progressive cycle is equal to the distance between two adjacent reaction containers 300 in the circumferential direction of the reaction disk 200.

[0052] In a preferred embodiment, the distance that the reaction vessel 300 advances in the opposite direction of rotation M of the reaction disk 200 over one progressive cycle is equal to the distance between any two adjacent reaction vessels 300 on the circumference of the reaction disk 200. That is, in two adjacent progressive cycles, the distance the same reaction vessel 300 moves on the circumference of the reaction disk 200 is equal to the distance between two adjacent reaction vessels 300, and the direction of movement is opposite to the rotation direction M of the reaction disk 200. Specifically, the distance between any two adjacent reaction vessels 300 on the circumference of the reaction disk 200 is defined as one container position. When the reaction disk 200 rotates for one progressive cycle, the reaction vessel 300 moves one container position, and the direction of movement is opposite to the rotation direction M of the reaction disk 200. Of course, as an alternative embodiment, it is also possible for the reaction vessel 300 to advance in the forward direction of rotation M of the reaction disk 200 over one progressive cycle to be equal to the distance between any two adjacent reaction vessels 300 on the circumference of the reaction disk 200.

[0053] In this embodiment, the rotation direction M of the reaction disk 200 is counterclockwise, and the reaction container 300 moves clockwise by one container position after one progressive cycle. Of course, as an alternative implementation, the rotation direction M of the reaction disk 200 can also be set to clockwise, in which case the reaction container 300 moves counterclockwise by one container position after one progressive cycle.

[0054] Preferably, after one rotation cycle, the reaction container 300 moves multiple container positions along the rotation direction M of the reaction disk 200, rather than moving only one container position. This is because if one rotation cycle progresses with a single container position, firstly, according to the working time requirements of each station, the arrangement of various functional devices of the biochemical analyzer (such as the sample dispensing device 400, reagent dispensing device 500, stirring device 600, detection device 700, cleaning system 100, etc.) in the circumferential direction of the reaction disk 200 cannot be realized (because some sequential execution stations require a very close distance, while others require a very far distance); secondly, it would cause the reaction disk 200 to operate in a rapid start-stop manner, which would make the rotation drive control of the reaction disk 200 very difficult to implement.

[0055] Preferably, the progressive cycle comprises less than or equal to ten rotational cycles. More preferably, the progressive cycle comprises less than or equal to five rotational cycles.

[0056] In a preferred embodiment of this invention, the progressive cycle includes four, five, or six rotation cycles, meaning that the reaction disk 200 completes one progressive cycle after four, five, or six rotation cycles. Of course, in specific applications, the number of rotation cycles included in the progressive cycle is not limited to four, five, or six; for example, it could be three, seven, or eight, etc.

[0057] During the process of the reaction plate 200 driving the reaction container 300 to rotate from the first cleaning section 112 to one progressive cycle, the suction section 122 is located downstream of the first cleaning section 112 and upstream of the first wiping section 113. That is, the cleaning process performed by the cleaning system 100 on the reaction container 300 is as follows: first, the reaction container 300 is cleaned by liquid injection through the first cleaning section 112, then the reaction container 300 is vacuumed through the suction section 122, and then the reaction container 300 is wiped through the first wiping section 113. Specifically, during the process of the reaction disk 200 driving a reaction vessel 300 to rotate from a first cleaning section 112 to a progressive cycle, the suction section 122 is disposed between the first cleaning section 112 and the first wiping section 113 along the rotation direction M of the reaction disk 200; and the distance between a suction section 122 and the first wiping section 113 closest to the first cleaning section 112 in the rotation direction M of the reaction disk 200 is equal to an integer multiple of the distance the reaction vessel 300 moves in one rotation cycle of the reaction disk 200 (the integer in the integer multiple is a value greater than or equal to one), and less than the distance the reaction vessel 300 moves in one progressive cycle of the reaction disk 200. In this embodiment, the vacuuming operation of a reaction vessel 300 and the water blank detection or wiping operation of the reaction vessel 300 can be performed in different rotation cycles of the same progressive cycle. Thus, without increasing the number of reaction vessels 300 required on the reaction plate 200 or increasing the progressive cycle and cleaning time, the liquid suction treatment after liquid injection and cleaning of the reaction vessel 300 can be achieved, thereby ensuring that the setting of the vacuuming part 122 does not reduce the utilization efficiency of the reaction vessel 300.

[0058] Preferably, the first cleaning device 110 and the vacuuming device 120 are two independent devices; that is, the vacuuming device 120 is not mounted on the first cleaning device 110, and the first cleaning device 110 is not mounted on the vacuuming device 120. The first cleaning device 110 is used at least to perform liquid injection cleaning on the reaction vessel 300 on the reaction plate 200, and the vacuuming device 120 is used at least to perform vacuuming (i.e., liquid suction) on the reaction vessel 300 on the reaction plate 200. Specifically, the liquid injection cleaning function of the first cleaning device 110 on the reaction vessel 300 includes: the first cleaning device 110 first suctions the waste liquid in the reaction vessel 300, and then injects cleaning liquid into the reaction vessel 300. The vacuuming function of the vacuuming device 120 on the reaction vessel 300 includes: the vacuuming device 120 suctions the residual liquid in the reaction vessel 300 after liquid injection cleaning by the first cleaning device 110. In this embodiment, by setting the first cleaning device 110 and the vacuum device 120 as two independent devices, it is convenient to distribute the first cleaning device 110 and the vacuum device 120 at different positions around the reaction plate 200. This facilitates the liquid suction treatment after liquid injection and cleaning of the reaction container 300 without increasing the number of reaction containers 300 required on the reaction plate 200 or increasing the cleaning time. As a result, the setting of the vacuum device 120 will not reduce the utilization efficiency of the reaction container 300.

[0059] In this embodiment, the first cleaning device 110 includes a first lifting drive mechanism 111 and at least one first cleaning section 112 for injecting liquid to clean the reaction container 300. The first lifting drive mechanism 111 is used to drive the first cleaning section 112 to move upward and downward. The first cleaning section 112 is mainly used to realize the functions of liquid suction and liquid injection. The first lifting drive mechanism 111 is provided so that, on the one hand, when the reaction plate 200 rotates, it can drive the first cleaning section 112 to rise to a certain height to avoid interference between the first cleaning section 112 and the reaction plate 200; on the other hand, when the reaction plate 200 stops, it can drive the first cleaning section 112 to fall to a certain height so that the first cleaning section 112 can suck up the liquid in the reaction container 300 on the reaction plate 200 and inject cleaning liquid into the reaction container 300.

[0060] Specifically, the first cleaning unit 112 can be directly mounted on the first lifting drive mechanism 111, or indirectly mounted on the first lifting drive mechanism 111, as long as the first lifting drive mechanism 111 can drive the first cleaning unit 112 to move upward and downward. In specific applications, when the reaction container 300 that needs to be cleaned rotates and stops directly below the first cleaning unit 112, the first lifting drive mechanism 111 drives the first cleaning unit 112 to move downward and clean the reaction container 300. After the first cleaning unit 112 has cleaned the reaction container 300, the first lifting drive mechanism 111 drives the first cleaning unit 112 to move upward. Then, the reaction container 300 rotates under the drive of the reaction plate 200 and moves away from directly below the first cleaning unit 112, thus completing one cleaning operation of the reaction container 300 by the first cleaning unit 112.

[0061] Preferably, the first cleaning unit 112 includes a first cleaning agent cleaning unit 1121 and a first clean water cleaning unit 1122, and the first cleaning device 110 includes at least one first cleaning agent cleaning unit 1121 and at least one first clean water cleaning unit 1122. The first cleaning agent cleaning unit 1121 and the first clean water cleaning unit 1122 are used to clean the reaction vessel 300 using different cleaning solutions. Specifically, the first cleaning agent cleaning unit 1121 uses a cleaning agent as the cleaning solution to perform liquid injection cleaning of the reaction vessel 300, and the first clean water cleaning unit 1122 uses clean water as the cleaning solution to perform liquid injection cleaning of the reaction vessel 300. In this embodiment, when the first cleaning device 110 cleans the reaction vessel 300, the reaction vessel 300 needs to undergo at least one cleaning with a cleaning agent and at least one cleaning with clean water, with the cleaning with cleaning agent performed first, thus ensuring the cleanliness of the reaction vessel 300.

[0062] Preferably, the first cleaning agent cleaning section 1121 includes a first suction section 1101 for drawing liquid from the reaction vessel 300 and a first injection section 1102 for injecting cleaning agent into the reaction vessel 300. The first injection section 1102 and the first suction section 1101 are arranged side by side, and the distance between the first injection section 1102 and the first suction section 1101 is less than the outer diameter of the reaction vessel 300. Specifically, the first injection section 1102 and the first suction section 1101 can be arranged side by side in any direction. For example, they can be arranged side by side in the radial direction, in the circumferential direction, or along a direction at a certain angle to the radial direction, that is, the line connecting the two forms a certain angle with the radial direction. In addition, the side-by-side arrangement of the first injection section 1102 and the first suction section 1101 can be a close-fitting side-by-side arrangement or a spaced-out side-by-side arrangement. The first cleaning agent cleaning section 1121 is a dual-channel structure that has both suction and injection functions. When the first cleaning agent cleaning unit 1121 performs liquid injection cleaning on the reaction container 300, it first draws the liquid in the reaction container 300 through the first liquid suction unit 1101, and then injects the cleaning agent into the reaction container 300 through the first liquid injection unit 1102.

[0063] Specifically, the first liquid suction part 1101 can be a suction needle or a pipette, and the first liquid injection part 1102 can be a liquid injection needle or a liquid injection tube.

[0064] Preferably, the first clean water cleaning section 1122 includes a third liquid suction section 1103 for suctioning liquid from the reaction vessel 300 and a third liquid injection section 1104 for injecting clean water into the reaction vessel 300. The third liquid injection section 1104 and the third liquid suction section 1103 are arranged side by side, and the distance between the third liquid injection section 1104 and the third liquid suction section 1103 is less than the outer diameter of the reaction vessel 300. Specifically, the third liquid injection section 1104 and the third liquid suction section 1103 can be arranged side by side in any direction. For example, they can be arranged side by side in the radial direction, in the circumferential direction, or along a direction at a certain angle to the radial direction, that is, the line connecting the two forms a certain angle with the radial direction. In addition, the side-by-side arrangement of the third liquid injection section 1104 and the third liquid suction section 1103 can be a close-fitting side-by-side arrangement or a spaced-out side-by-side arrangement. The first clean water cleaning section 1122 is a dual-channel structure that has both liquid suction and liquid injection functions. When the first cleaning agent cleaning unit 1121 performs liquid injection cleaning on the reaction vessel 300, the liquid in the reaction vessel 300 is first drawn up by the third liquid suction unit 1103, and then clean water is injected into the reaction vessel 300 by the third liquid injection unit 1104, thereby completing one liquid injection cleaning of the reaction vessel 300 by the first clean water cleaning unit 1122.

[0065] Specifically, the third suction part 1103 can be a suction needle or a pipette, and the third injection part 1104 can be an injection needle or an injection tube.

[0066] In a preferred embodiment of this invention, the first cleaning device 110 includes two first cleaning agent cleaning sections 1121 sequentially distributed along the rotation direction M of the reaction disk 200. During the cleaning process of the reaction container 300 by the cleaning system 100, the two first cleaning agent cleaning sections 1121 sequentially distributed along the rotation direction M of the reaction disk 200 will sequentially clean the reaction container 300 with cleaning agent. That is, the reaction container 300 will undergo two stages of cleaning agent cleaning during the cleaning process. This ensures the cleaning effect without causing the cleaning time to be too long. Of course, in specific applications, the number of first cleaning agent cleaning sections 1121 sequentially distributed along the rotation direction M of the reaction disk 200 is not limited to two; for example, it can also be one, three, or four, etc.

[0067] In a preferred embodiment of this invention, the first cleaning device 110 includes four first clean water cleaning sections 1122 sequentially distributed along the rotation direction M of the reaction disk 200. During the cleaning process of the reaction container 300 by the cleaning system 100, the four first clean water cleaning sections 1122 sequentially distributed along the rotation direction M of the reaction disk 200 will sequentially clean the reaction container 300 with clean water. That is, the reaction container 300 will undergo four stages of clean water cleaning during the cleaning process. This not only ensures the cleaning effect but also prevents the cleaning time from being too long. Of course, in specific applications, the number of first clean water cleaning sections 1122 sequentially distributed along the rotation direction M of the reaction disk 200 is not limited to four; for example, it can also be one, two, three, or five, etc.

[0068] In one implementation, the water blank detection position is positioned in the opposite direction of the rotation direction of the reaction disk 200 between the third and fourth first clean water sections 112, that is, between the first-stage first clean water cleaning section 1122 and the second-stage first clean water cleaning section 1122. Of course, in specific applications, the location of the water blank detection position is not limited to this; it is sufficient that the water blank detection position is located on the side of the idle position 114 away from the first wiping section 113, so that water blank detection can be performed after the final stage of liquid injection cleaning is completed and one progressive cycle has elapsed.

[0069] In this embodiment, the suction device 120 includes a second lifting drive mechanism 121 and at least one suction section 122 for suctioning liquid from the reaction vessel 300. The second lifting drive mechanism 121 drives the suction section 122 to move upward and downward. The suction section 122 is mainly used to perform the liquid suction function. The second lifting drive mechanism 121 is configured to, on the one hand, drive the suction section 122 to rise to a certain height when the reaction plate 200 rotates to avoid interference between the suction section 122 and the reaction plate 200; on the other hand, drive the suction section 122 to descend to a certain height when the reaction plate 200 stops so that the suction section 122 can suction liquid from the reaction vessel 300 on the reaction plate 200. The first lifting drive mechanism 111 and the second lifting drive mechanism 121 are independently configured, that is, the first lifting drive mechanism 111 and the second lifting drive mechanism 121 are two lifting drive mechanisms.

[0070] Specifically, the suction unit 122 can be directly mounted on the second lifting drive mechanism 121, or indirectly mounted on the second lifting drive mechanism 121, as long as the second lifting drive mechanism 121 can drive the suction unit 122 to move upward and downward. In specific applications, when the reaction vessel 300 that needs to be suctioned rotates and stops directly below the suction unit 122, the second lifting drive mechanism 121 drives the suction unit 122 to move downward and perform suction on the reaction vessel 300. After the suction unit 122 has completed suction on the reaction vessel 300, the second lifting drive mechanism 121 drives the suction unit 122 to move upward. Then, the reaction vessel 300 rotates under the drive of the reaction disk 200 and leaves directly below the suction unit 122, thus completing one suction operation of the reaction vessel 300 by the suction unit 122.

[0071] Specifically, the first cleaning agent cleaning section 1121 is disposed between the first clean water cleaning section 1122 and the suction section 122 along the rotation direction M of the reaction disk 200.

[0072] Specifically, the first wiping device includes at least one first wiping section 113 for wiping the liquid inside the reaction vessel 300. The first wiping section 113 and the vacuum section 122 are independently arranged. The independent arrangement of the first wiping section 113 and the vacuum section 122 means that the first wiping section 113 is not located on the vacuum section 122, and the vacuum section 122 is not located on the first wiping section 113. After the cleaning system 100 completes the vacuuming process of the reaction vessel 300, it also wipes the reaction vessel 300 using the first wiping section 113, thereby further reducing the amount of residual liquid inside the reaction vessel 300. Furthermore, since the vacuuming part 122 and the first wiping part 113 are independently arranged, it is beneficial to ensure the consistency of the gap between the first wiping part 113 entering the reaction container 300 and the wall of the reaction container 300. This not only helps to ensure the consistency of liquid residue in the reaction container 300, but also helps to reduce the positioning accuracy requirements of the first cleaning device 110, the vacuuming device 120 and the reaction plate 200, thereby reducing the design and manufacturing difficulty of the first cleaning device 110, the vacuuming device 120, the first wiping device and the reaction plate 200.

[0073] Preferably, in this embodiment, the first wiping device and the first cleaning device 110 are integrally arranged, that is, the wiping device is integrated into the first cleaning device 110. Both the first cleaning section 112 and the first wiping section 113 are driven to rise and fall by the first lifting drive mechanism 111. During the process of the reaction disk 200 driving the reaction container 300 to rotate from one first cleaning section 112 to one progressive cycle, the suction section 122 is located between the first cleaning section 112 and the first wiping section 113 along the rotation direction M of the reaction disk 200; that is, the suction section 122 is located downstream of the first cleaning section 112, and the first wiping section 113 is located downstream of the suction section 122. An idle position 114 is located between the first wiping section 113 and the first cleaning section 112 along the rotation direction of the reaction disk 200. In this embodiment, the first wiping device is integrated into the first cleaning device 110. Both the first cleaning section 112 and the first wiping section 113 are driven to rise and fall by the first lifting drive mechanism 111, which eliminates the need for a lifting drive mechanism, thereby reducing the cost of the cleaning system 100 and facilitating the miniaturization of the biochemical analyzer. Of course, in specific applications, when the first cleaning device 110 and the vacuum device 120 are two independent devices, the arrangement of the first wiping device is not limited to this. For example, as an alternative embodiment, the vacuum device 120 and the first wiping device can be designed as a single unit. In this case, the first lifting drive mechanism 111 is used to drive the first cleaning section 112 to rise and fall, and the second lifting drive mechanism 121 is used to drive the vacuum section 122 and the first wiping section 113 to rise and fall.

[0074] Specifically, the first wiping part 113 can be directly mounted on the first lifting drive mechanism 111, or indirectly mounted on the first lifting drive mechanism 111, as long as the first lifting drive mechanism 111 can drive the first wiping part 113 to move upward and downward. The principle of the first lifting drive mechanism 111 driving the first wiping part 113 to move can be referred to the principle of the first lifting drive mechanism 111 driving the first cleaning part 112 to move, and will not be described in detail here.

[0075] Preferably, during the process of the reaction disk 200 driving the reaction container 300 to rotate from a first cleaning section 112 to one progressive cycle, the distance between the suction section 122 and the first wiping section 113 closest to the first cleaning section 112 in the rotation direction M of the reaction disk 200 is equal to an integer multiple of the distance the reaction container 300 moves in one rotation cycle of the reaction disk 200 (the integer multiple is a value greater than or equal to one), and less than the distance the reaction container 300 moves in one progressive cycle of the reaction disk 200. When the distance between a suction section 122 and the first wiping section 113 closest to the first cleaning section 112 in the rotation direction M of the reaction disk 200 is equal to one time the distance the reaction container 300 travels in one rotation cycle of the reaction disk 200, the reaction container 300 can move directly to the first wiping section 113 for wiping after being emptied by the suction section 122 of the suction device 120 in the next rotation cycle; when the distance between the suction section 122 and the first wiping section 113 closest to the first cleaning section 112 in the rotation direction M of the reaction disk 200 is equal to at least twice the distance the reaction container 300 travels in one rotation cycle of the reaction disk 200, the reaction container 300 will move to the first wiping section 113 for wiping after being emptied by the suction section 122 of the suction device 120 for at least two rotation cycles.

[0076] Specifically, in this embodiment, the suction section 122 is a single-channel structure that only has the function of suctioning liquid and not the function of injecting liquid, and it can be a suction needle or a pipette.

[0077] In one embodiment, the first wiping part 113 can be a suction needle with a wiping head at one end or a suction tube with a wiping head at one end, that is, the first wiping part 113 has both wiping and liquid suction functions. In this embodiment, the suction part 122 first suctions liquid from the reaction container 300, and then the first wiping part 113 performs simultaneous liquid suction and wiping treatment on the emptied reaction container 300. In this way, the residual amount of liquid in the reaction container 300 can be greatly reduced, making the reaction container 300 very clean after being treated by the first wiping part 113.

[0078] In a preferred embodiment of this invention, the vacuum device 120 includes a vacuum section 122 along the rotation direction M of the reaction disk 200, and the first cleaning device 110 includes two first wiping sections 113 sequentially distributed along the rotation direction M of the reaction disk 200. During the cleaning process, the reaction container 300 undergoes a first-stage vacuum treatment and a second-stage wiping treatment. This approach helps reduce the amount of residual liquid in the reaction container 300 without causing excessively long cleaning times.

[0079] In one implementation, among the first cleaning sections 112 and the first wiping sections 113, the distance between the closest first cleaning section 112 and the closest first wiping section 113 is equal to twice the distance that the reaction vessel 300 moves circumferentially relative to the reaction disk 200 after one progressive cycle. That is, the distance between the last first cleaning section 112 and the first first wiping section 113 is equal to two container positions. Thus, after the last first cleaning section 112 has finished cleaning, the reaction vessel 300 needs to go through two progressive cycles before it moves to the bottom of the first wiping section 113. This is mainly to reserve one progressive cycle time for water blank detection to ensure the accuracy of water blank detection.

[0080] In one implementation, an idle position 114 is formed at the midpoint between the closest first cleaning section 112 and the closest first wiping section 113; that is, an idle position 114 is formed at the midpoint between the last-stage first cleaning section 112 and the first-stage first wiping section 113. The distance between the idle position 114 and the last-stage first cleaning section 112 is equal to the distance the reaction vessel 300 moves circumferentially relative to the reaction disk 200 over one progressive cycle (i.e., one container position), and the distance between the idle position 114 and the first-stage first wiping section 113 is equal to the distance the reaction vessel 300 moves circumferentially relative to the reaction disk 200 over one progressive cycle. The idle position 114 is used by the cleaning system 100 to clean the reaction vessel 300 after it has been cleaned by the first cleaning section 112. That is, during the idle position 114, the cleaning system 100 does not perform any operation on the reaction vessel 300. The purpose of setting up the idle position 114 is mainly to reserve a progressive cycle time for water blank detection between the liquid injection cleaning and wiping treatment. The idle position 114 can be a blank position, meaning no components are installed, or it can be a position where a needle that does not perform any action is installed.

[0081] In one embodiment, the suction unit 122 is used to suction the residual liquid in the reaction vessel 300 after it has been cleaned by the first cleaning unit 112 and passed the idle position 114. During the process of the reaction disk 200 rotating the reaction vessel 300 from the idle position 114 in one progressive cycle, the first cleaning unit 112 is positioned between the idle position 114 and the suction unit 122 along the rotation direction of the reaction disk 200. The distance between the idle position 114 and the suction unit 122 in the rotation direction M of the reaction disk 200 is equal to an integer multiple of the distance the reaction vessel 300 travels in one rotation cycle of the reaction disk 200, and less than the distance the reaction vessel 300 travels in one progressive cycle of the reaction disk 200. The integer multiple is a value greater than or equal to one. By adopting this implementation scheme, the water blank detection and vacuum treatment of a reaction vessel 300 can be carried out in different rotation cycles of a progressive cycle, which makes it easier for the vacuum treatment of the reaction vessel 300 by the vacuum section 122 to not occupy an independent progressive cycle, and thus the setting of the vacuum section 122 will not reduce the utilization efficiency of the reaction vessel 300.

[0082] Furthermore, this embodiment also provides a biochemical analyzer, which includes a reaction disk 200, a rotary drive device (not shown), a sample dispensing device 400, a reagent dispensing device 500, a stirring device 600, a detection device 700, and the aforementioned cleaning system 100; the reaction disk 200 is provided with a plurality of circumferentially distributed receiving slots 210 for placing reaction containers 300; the rotary drive device is used to drive the reaction disk 200 to rotate; the detection device 700 can be used to perform water blank detection on the reaction container 300 on the reaction disk 200, and the detection device 700 can also be used to measure the absorbance of the reaction solution made of sample and reagent in the reaction container 300; the first cleaning device 110, the vacuum device 120, the sample dispensing device 400, the reagent dispensing device 500, the stirring device 600, and the detection device 700 are distributed along the circumferential direction of the reaction disk 200. The sample dispensing device 400 is used to dispense samples into the reaction vessel 300, the reagent dispensing device 500 is used to dispense reagents into the reaction vessel 300, the stirring device 600 is used to stir the liquid in the reaction vessel 300, and the detection device 700 can be used to perform water blank detection on the reaction vessel 300. The biochemical analyzer provided in this embodiment of the invention, due to the adoption of the aforementioned cleaning system 100, not only ensures the stability of the biochemical analyzer's test results but also ensures the efficiency of the reaction vessel 300.

[0083] Specifically, in this embodiment, the detection device 700 is used both to perform water blank detection on the reaction vessel 300 after it has been cleaned by each of the first cleaning sections 112 and before the liquid is aspirated by the suction section 122, and to perform sample detection on the reaction solution made from the sample and reagents in the reaction vessel 300. That is, in this embodiment, the device for performing water blank detection and the device for performing sample detection are the same device, realizing time-sharing reuse of the device, thereby simplifying the structure of the biochemical analyzer. Of course, in specific applications, as an alternative implementation, the device for performing water blank detection and the device for performing sample detection can also be two independent devices.

[0084] In one embodiment, the detection device 700 is used to perform sample detection on the reaction liquid made of sample and reagent in the reaction vessel 300; and to perform water blank detection on the reaction vessel 300 after it has been cleaned by the first cleaning section 112 and passed through the idle position 114 before the liquid is drawn by the suction section 122.

[0085] Preferably, the reagent dispensing device 500 includes a first reagent dispensing mechanism 510 and a second reagent dispensing mechanism 520, which are arranged circumferentially around the reaction dish 200. The first reagent dispensing mechanism 510 dispenses a first reagent into the reaction container 300, and the second reagent dispensing mechanism 520 dispenses a second reagent into the reaction container 300 to meet the testing requirements of different samples. Of course, in specific applications, the reagent dispensing device 500 may also include only one of the first reagent dispensing mechanism 510 and the second reagent dispensing mechanism 520.

[0086] Preferably, the stirring device 600 includes a first stirring mechanism 610 and a second stirring mechanism 620, which are arranged circumferentially around the reaction dish 200. The first stirring mechanism 610 and the second stirring mechanism 620 are used to stir the reaction liquid in the reaction vessel 300 at different stages. Of course, in specific applications, the stirring device 600 may also include only one of the first stirring mechanism 610 and the second stirring mechanism 620.

[0087] Preferably, the receiving tank 210 includes a first receiving tank 211210 and a second receiving tank 212210. Multiple first receiving tanks 211210 are distributed along a first circumference on the reaction disk 200, and multiple second receiving tanks 212210 are distributed along a second circumference on the reaction disk 200. The second circumference is located on the outer periphery of the first circumference. In this embodiment, by dividing the receiving tanks 210 on the reaction disk 200 into inner and outer rings, and by allowing the first cleaning device 110, the vacuum device 120, the sample dispensing device 400, the reagent dispensing device 500, the stirring device 600, and the detection device 700 to respectively process the inner and outer rings of the reaction containers 300, the sample analysis efficiency of the biochemical analyzer can be improved. Of course, in specific applications, as an alternative implementation, the distribution of the receiving grooves 210 on the reaction disk 200 is not necessarily in the form of inner and outer rings. It can also be that multiple receiving grooves 210 are distributed along the same circumference on the reaction disk 200, that is, the receiving grooves 210 on the reaction disk 200 can also be only one ring.

[0088] In this embodiment, the first cleaning device 110 includes at least one set of first cleaning sections 112 and at least one set of first wiping sections 113. Each set of first cleaning sections 112 includes two first cleaning sections 112 that are sequentially distributed along the radial direction of the reaction plate 200 and correspond to the positions of the first accommodating groove 211210 and the second accommodating groove 212210, respectively. That is, each set of first cleaning sections 112 includes a first inner ring cleaning section and a first outer ring cleaning section. The first inner ring cleaning section is used to clean the reaction container 300 located in the first accommodating groove 211210, and the first outer ring cleaning section is used to clean the reaction container 300 located in the second accommodating groove 212210. Each group of first wiping sections 113 includes two first wiping sections 113 arranged radially along the reaction disk 200 and corresponding to the positions of the first receiving groove 211210 and the second receiving groove 212210, respectively. That is, each group of first wiping sections 113 includes an inner ring wiping section and an outer ring wiping section. The inner ring wiping section is used to wipe the reaction container 300 located in the first receiving groove 211210, and the outer ring wiping section is used to wipe the reaction container 300 located in the second receiving groove 212210.

[0089] In this embodiment, the vacuum suction device 120 includes a set of vacuum suction sections 122. The set of vacuum suction sections 122 consists of two vacuum suction sections 122 that are arranged radially along the reaction disk 200 and correspond to the positions of the first accommodating groove 211210 and the second accommodating groove 212210, respectively. That is, the set of vacuum suction sections 122 includes an inner ring vacuum suction section 122 and an outer ring vacuum suction section 122. The inner ring vacuum suction section 122 is used to vacuum the reaction container 300 located in the first accommodating groove 211210, and the outer ring vacuum suction section 122 is used to vacuum the reaction container 300 located in the second accommodating groove 212210.

[0090] Specifically, the reaction vessel 300 can be a reaction cup or a reaction test tube, etc.

[0091] In one implementation, the biochemical analyzer also includes a controller for controlling the operation of the rotary drive, sample dispensing device 400, reagent dispensing device 500, stirring device 600, detection device 700, and cleaning system 100. The controller is configured to control the suction operation of the suction unit 122 and the water blank detection of the detection device 700, or the wiping operation of a first wiping unit 113, at different rotation cycles within the same progressive cycle of the reaction disk 200.

[0092] Furthermore, this embodiment also provides a control method for a biochemical analyzer, which includes a first cleaning step S10, a water blank detection step S20, and a vacuum step S30. The first cleaning step S10 is used to clean the reaction vessel 300 with a cleaning solution; the water blank detection step S20 is used to detect whether the reaction vessel 300 meets the usage requirements after being cleaned by the first cleaning step S10; and the vacuum step S30 is used to vacuum (remove the liquid from the reaction vessel 300) the reaction vessel 300 that has passed the water blank detection step S20. The control method for the biochemical analyzer is executed by the aforementioned controller.

[0093] The first cleaning step S10 includes cleaning the reaction container 300 on the reaction plate 200 by injecting liquid through the first cleaning part 112; the water blank detection step S20 includes performing a blank test on the reaction container 300 after completing the first cleaning step S10 and passing the water blank detection position through the detection device 700; the vacuuming step S30 includes: vacuuming the reaction container 300 after completing the water blank detection step S20 through the vacuuming part 122; during the process of the reaction plate 200 driving the reaction container 300 to rotate from the idle position 114 for one progressive cycle, the vacuuming part 122 is located between the first cleaning part 112 and the idle position 114 along the rotation direction of the reaction plate 200; the distance between the vacuuming part 122 and the idle position 114 in the rotation direction M of the reaction plate 200 is equal to an integer multiple of the distance the reaction container 300 moves in one rotation cycle of the reaction plate 200 (the integer multiple is a value greater than or equal to one), and less than the distance the reaction container 300 moves in one progressive cycle of the reaction plate 200.

[0094] Preferably, the first cleaning step S10 includes: cleaning the reaction vessel 300 on the reaction plate 200 by injecting liquid through the first cleaning section 112 of the first cleaning device 110. The water blank detection step S20 includes: performing a blank test on the reaction vessel 300 after completing the first cleaning step S10 by the detection device 700. The vacuuming step S30 includes: vacuuming the reaction vessel 300 after completing the water blank detection step S20 by the vacuuming section 122 of the vacuuming device 120. The first cleaning device 110 and the vacuuming device 120 are two independent devices. The control method for the biochemical analyzer provided in this embodiment uses two independent devices for the first cleaning step S10 and the vacuuming step S30. This allows the first cleaning device 110 and the vacuuming device 120 to be arranged so that the first cleaning device 110 and the vacuuming device 120 can process the reaction container 300 in two different rotation cycles within one progressive cycle of the reaction disk 200, without the need to set a separate progressive cycle for the vacuuming step S30. This reduces the liquid residue in the reaction container 300 without increasing the number of reaction containers 300 required on the reaction disk 200 or increasing the cleaning time, thereby improving the utilization efficiency of the reaction container 300.

[0095] Preferably, the first cleaning step S10 includes a cleaning agent cleaning step S11 and a water cleaning step S12. The cleaning agent cleaning step S11 involves cleaning the reaction vessel 300 on the reaction tray 200 with a cleaning agent using the first cleaning agent cleaning section 1121 of the first cleaning section 112. The water cleaning step S12 involves rinsing the reaction vessel 300 with clean water using the first clean water cleaning section 1122 of the first cleaning section 112. The cleaning agent cleaning step S11 cleans the reaction vessel 300 with a cleaning agent, and the water cleaning step S12 cleans the reaction vessel 300 with clean water. This process, where the reaction vessel 300 is first cleaned with a cleaning agent and then rinsed with clean water, helps ensure the cleanliness of the reaction vessel 300. The cleaning agent cleaning step S11 and the water cleaning step S12 are performed at different progressive cycles on the reaction tray 200.

[0096] Preferably, the cleaning agent cleaning step S11 includes: firstly, absorbing the liquid in the reaction vessel 300 through the first liquid absorption section 1101 of the first cleaning agent cleaning section 1121, and then injecting cleaning agent into the reaction vessel 300 through the first liquid injection section 1102 of the first cleaning agent cleaning section 1121 to clean the reaction vessel 300. The water cleaning step S12 includes: firstly, absorbing the liquid in the reaction vessel 300 through the third liquid absorption section 1103 of the first water cleaning section 1122, and then injecting water into the reaction vessel 300 through the third liquid injection section 1104 of the first water cleaning section 1122 to clean the reaction vessel 300. Both the first cleaning agent cleaning section 1121 and the first water cleaning section 1122 are dual-channel structures with liquid absorption and liquid injection functions.

[0097] Preferably, the first cleaning step S10 includes at least two sequential cleaning agent cleaning steps S11 and at least two sequential water rinsing steps S12. After each cleaning agent cleaning step S11 is completed in the first cleaning step S10, each water rinsing step S12 is performed sequentially; the water blank detection step S20 is performed after the last water rinsing step S12 is completed. The vacuuming step S30 is performed after the water blank detection step S20 is completed and the detection is qualified.

[0098] In a preferred embodiment of this invention, the first cleaning step S10 includes two sequential cleaning agent cleaning steps S11 and four sequential water cleaning steps S12, which provides good cleaning effect and does not take too long. Of course, in specific applications, the number of cleaning agent cleaning steps S11 and water cleaning steps S12 included in the first cleaning step S10 is not limited to this.

[0099] Preferably, the control method of the biochemical analyzer further includes a wiping step S40 after the vacuuming step S30. The wiping step S40 includes controlling a wiping unit, which is independent of the vacuuming unit 122, to wipe the reaction container 300 after the vacuuming step S30 is completed. The wiping step S40 helps to further reduce the amount of liquid residue in the reaction container 300, thereby improving the stability of the test results of the biochemical analyzer. Since the vacuuming unit 122 in the vacuuming step S30 and the wiping unit in the wiping step S40 are independently set, that is, the vacuuming step S30 and the wiping step S40 are performed independently, it helps to ensure the consistency of the gap between the wiping unit entering the reaction container 300 and the wall of the reaction container 300. This helps to ensure the consistency of liquid residue in the reaction container 300 and also reduces the positioning accuracy requirements of the first cleaning device 110, the vacuuming device 120, and the reaction plate 200.

[0100] Preferably, the wiping step S40 includes a first wiping step S41, which includes wiping the reaction vessel 300 after the vacuuming step S30 is completed using a first wiping part 113 of the first cleaning device 110. The first wiping step S41 is performed using the first wiping part 113 provided on the first cleaning device 110, thus eliminating the need for a separate wiping device and reducing the cost and size of the biochemical analyzer.

[0101] As one implementation method, the control method of the biochemical analyzer further includes: controlling the water blank detection step S20 and the first wiping step S41 to be performed in two adjacent progressive cycles of the reaction disk 200; and controlling the vacuum step S30 and the water blank detection step S20 to be performed in different rotation cycles of the same progressive cycle of the reaction disk 200. Of course, in specific applications, as an alternative implementation, when controlling the water blank detection step S20 and the first wiping step S41 to be performed in two adjacent progressive cycles of the reaction disk 200, the vacuuming step S30 and the water blank detection step S20 can also be controlled to be performed in two adjacent progressive cycles of the reaction disk 200, while the vacuuming step S30 and the first wiping step S41 can be controlled to be performed in different rotation cycles of the same progressive cycle of the reaction disk 200; or, as another alternative implementation, when the final liquid injection cleaning step and the water blank detection step S20 are set to be greater than or equal to one progressive cycle, the water blank detection step S20, the vacuuming step S30, and the first wiping step S41 can also be controlled to be performed in different rotation cycles of the same progressive cycle of the reaction disk 200.

[0102] Preferably, the control method of the biochemical analyzer further includes a third wiping step S42 after the first wiping step S41. The third wiping step S42 includes wiping the reaction container 300 after the first wiping step S41 by another first wiping part 113 of the first cleaning device 110. The first wiping part 113 in the first wiping step S41 and the first wiping part 113 in the third wiping step S42 are two independent components. That is, the first cleaning device 110 has two first wiping parts 113 arranged sequentially along the circumference of the reaction disk 200, and the distance between these two first wiping parts 113 is equal to one container position. In this embodiment, after the evacuation step S30 is completed, the reaction container 300 needs to undergo two wiping steps, the first wiping step S41 and the third wiping step S42, which helps to reduce the amount of liquid residue in the reaction container 300.

[0103] The cleaning system 100, biochemical analyzer, and control method for the biochemical analyzer provided in this embodiment utilize an independent suction device 120 to evacuate the liquid from the reaction vessel 300 before the wiping unit begins wiping. This ensures that when the wiping unit enters the reaction vessel 300, there is no longer a significant amount of liquid present, effectively eliminating problems such as liquid entrainment caused by uneven gaps between the wiping unit and the reaction vessel 300, and reducing cleaning residue. Furthermore, the independent suction device 120 does not alter the existing progressive flow and mechanism of the reaction vessel 300, eliminating the need for additional suction container positions, reducing the number of container positions, and lowering the implementation difficulty.

[0104] As a preferred embodiment of this invention, the cleaning system 100 includes a two-stage first cleaning agent cleaning section 1121, a four-stage first clean water cleaning section 1122, a first-stage idle position 114, a first-stage vacuum section 122, and a two-stage first wiping section 113. The reaction disk 200 rotates counterclockwise, and a reaction container 300 advances one container position clockwise after one progressive cycle. The progressive cycle includes five rotation cycles. The following uses this preferred embodiment as an example to illustrate the cleaning and water blank detection process of a reaction container 300a:

[0105] At the initial position of the first progressive cycle, the reaction vessel 300a stops below the first-stage first cleaning agent cleaning section 1121 (the leftmost first cleaning agent cleaning section 1121 in the figure). The first-stage first cleaning agent cleaning section 1121 uses cleaning agent to clean the reaction vessel 300a. After cleaning, the reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles, so that the reaction vessel 300a progresses to the initial position of the second progressive cycle.

[0106] At the initial position of the second progressive cycle, the reaction vessel 300a stops below the second-stage first cleaning agent cleaning section 1121. The second-stage first cleaning agent cleaning section 1121 uses cleaning agent to clean the reaction vessel 300a. After cleaning, the reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles, so that the reaction vessel 300a progresses to the initial position of the third progressive cycle.

[0107] At the initial position of the third progressive cycle, the reaction vessel 300a stops below the first stage first clean water cleaning section 1122. The first stage first clean water cleaning section 1122 uses clean water to clean the reaction vessel 300a. After cleaning, the reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles, so that the reaction vessel 300a progresses to the initial position of the fourth progressive cycle.

[0108] At the initial position of the fourth progressive cycle, the reaction vessel 300a stops below the second-stage first clean water cleaning section 1122. The second-stage first clean water cleaning section 1122 uses clean water to clean the reaction vessel 300a. After cleaning, the reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles, so that the reaction vessel 300a progresses to the initial position of the fifth progressive cycle.

[0109] At the initial position of the fifth progressive cycle, the reaction vessel 300a stops below the third-stage first clean water cleaning section 1122. The third-stage first clean water cleaning section 1122 uses clean water to clean the reaction vessel 300a. After cleaning, the reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles, so that the reaction vessel 300a progresses to the initial position of the sixth progressive cycle.

[0110] At the initial position of the sixth progressive cycle, the reaction vessel 300a stops below the fourth-stage first clean water cleaning section 1122. The fourth-stage first clean water cleaning section 1122 uses clean water to clean the reaction vessel 300a. After cleaning, clean water for water blank detection is left in the reaction vessel 300a. The reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles, so that the reaction vessel 300a progresses to the initial position of the seventh progressive cycle.

[0111] At the initial position of the seventh progressive cycle, the reaction vessel 300a stops below the idle position 114. The cleaning system 100 does not perform any treatment on the reaction vessel 300a. After the idle time is up, the reaction disk 200 drives the reaction vessel 300a to rotate counterclockwise for five rotation cycles so that the reaction vessel 300a can advance to the initial position of the eighth progressive cycle.

[0112] During the rotation process of the first rotation cycle of the seventh progressive cycle, the detection device 700 performs water blank detection on the reaction vessel 300a that rotates from the second-stage first clean water cleaning section 1122 to the first-stage first clean water cleaning section 1122.

[0113] At the end of the fourth rotation cycle of the seventh progressive cycle, the reaction vessel 300a stops below the suction section 122, and the suction section 122 performs liquid suction treatment on the reaction vessel 300a.

[0114] At the initial position of the eighth progressive cycle, the reaction container 300a stops below the first wiping section 113 of the first stage. The first wiping section 113 of the first stage wipes the reaction container 300a. After wiping, the reaction disk 200 drives the reaction container 300a to rotate counterclockwise for five rotation cycles so that the reaction container 300a can advance to the initial position of the ninth progressive cycle.

[0115] At the initial position of the ninth progressive cycle, the reaction vessel 300a stops below the second-stage first wiping section 113, and the second-stage first wiping section 113 wipes the reaction vessel 300a.

[0116] Example 2:

[0117] Reference Figure 1 , Figure 4 and Figure 6-8 As shown, the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment differ from those in Embodiment 1 mainly in the arrangement of the wiping parts. Specifically, in Embodiment 1, only the first wiping part 113 is provided on the first cleaning device 110; while in this embodiment, in addition to providing the first wiping part 113 on the first cleaning device 110, a second wiping part 123 is also provided on the suction device 120. In this embodiment, by providing wiping parts on both the first cleaning device 110 and the suction device 120, the amount of liquid residue in the reaction container 300 can be further reduced without increasing the number of reaction containers 300 required on the reaction plate 200 or increasing the cleaning time.

[0118] Specifically, in this embodiment, the wiping unit further includes at least one second wiping unit 123, which is driven to rise and fall by the second lifting drive mechanism 121. The second wiping unit 123 can be directly mounted on the second lifting drive mechanism 121 or indirectly mounted on the second lifting drive mechanism 121, as long as the second lifting drive mechanism 121 can drive the second wiping unit 123 to rise and fall. The principle of the second lifting drive mechanism 121 driving the second wiping unit 123 can be referred to the principle of the second lifting drive mechanism 121 driving the suction unit 122, and will not be described in detail here. Of course, in specific applications, as an alternative implementation, the second wiping unit 123 can also be driven to rise and fall by a lifting drive mechanism independent of the second lifting drive mechanism 121.

[0119] Preferably, during the process of the reaction disk 200 driving the reaction vessel 300 to rotate from one first cleaning section 112 in one progressive cycle, the second wiping section 123 is disposed between the first cleaning section 112 and the suction section 122 along the rotation direction M of the reaction disk 200; the suction section 122 is disposed between the second wiping section 123 and the first wiping section 113 along the rotation direction M of the reaction disk 200, and the first wiping section 113 is disposed between the suction section 122 and the first cleaning section 112 along the rotation direction M of the reaction disk 200. In this embodiment, the second wiping section 123 is located upstream of the suction section 122. During the process of the reaction disk 200 driving the reaction vessel 300 to rotate from one first cleaning section 112 in one progressive cycle, the first cleaning section 112, the second wiping section 123, the suction section 122, and the first wiping section 113 are arranged sequentially along the rotation direction M of the reaction disk 200. The second wiping section 123 is used to wipe the inside of the reaction vessel 300 after it has been wiped by the first wiping section 113112.

[0120] In one embodiment, among each suction section 122 and each second wiping section 123, the distance between the closest suction section 122 and the second wiping section 123 is equal to the distance that the reaction vessel 300 moves circumferentially relative to the reaction disk 200 on the reaction disk 200 after one progressive cycle. Adjacent suction sections 122 and second wiping sections 123 are used to perform suction treatment and wiping treatment on the reaction vessel 300 in two adjacent progressive cycles, respectively.

[0121] The main difference between the control method of the biochemical analyzer provided in this embodiment and that in Embodiment 1 is that the control method of the biochemical analyzer provided in this embodiment includes a second wiping step S43 after the first wiping step S41 and before the third wiping step S42. The second wiping step S43 includes wiping the reaction container 300 after the first wiping step S41 is completed by the second wiping part 123 of the suction device 120. In this embodiment, after the vacuuming step S30 is completed, the reaction container 300 sequentially performs the first wiping step S41, the second wiping step S43, and the third wiping step S42. The third wiping step S42 is used to wipe the reaction container 300 after the second wiping step S43 is completed. That is, wiping on the first cleaning device 110 and wiping on the vacuuming device 120 are performed alternately. This allows the second wiping step S43 and the third wiping step S42, or the second wiping step S43 and the first wiping step S41, to be performed in two different rotation cycles within one progressive cycle of the reaction disk 200, without the need to set a separate progressive cycle for the second wiping step S43. This reduces the liquid residue in the reaction container 300 without increasing the number of reaction containers 300 required on the reaction disk 200 or increasing the cleaning time.

[0122] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized with reference to Embodiment 1, and will not be described in detail here.

[0123] Example 3:

[0124] Reference Figure 1 , Figure 4 and Figure 6-9 As shown, the main difference between the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment and those in Embodiment 2 lies in the different positions of the second wiping part 123. Specifically, in Embodiment 2, during the process of the reaction disk 200 driving the reaction container 300 to rotate from one first cleaning part 112 in one progressive cycle, the second wiping part 123 is located between the first cleaning part 112 and the suction part 122 along the rotation direction M of the reaction disk 200, that is, the second wiping part 123 is located upstream of the suction part 122; while in this embodiment, during the process of the reaction disk 200 driving the reaction container 300 to rotate from one first cleaning part 112 in one progressive cycle, the second wiping part 123 is located between the suction part 122 and the first wiping part 113 along the rotation direction M of the reaction disk 200, that is, the second wiping part 123 is located downstream of the suction part 122.

[0125] In one embodiment, the suction device 120 further includes at least one second wiping section 123. During the process of the reaction disk 200 driving the reaction container 300 to rotate from one first cleaning section 112 in one progressive cycle, the suction section 122 is positioned between the first cleaning section 112 and the second wiping section 123 along the rotation direction M of the reaction disk 200, and the second wiping section 123 is positioned between the suction section 122 and the first wiping section 113 along the rotation direction M of the reaction disk 200. The distance between the second wiping section 123 and the suction section 122, or between one of the first wiping sections 113, in the rotation direction M of the reaction disk 200 is an integer multiple of the distance the reaction container 300 travels in one rotation cycle of the reaction disk 200. In this embodiment, the second wiping section 123 is used to wipe the reaction container 300 after it has been suctioned by the suction section 122 and before it has been wiped by the first wiping section 113, or to wipe the reaction container 300 after it has been wiped by one of the first wiping sections 113.

[0126] The control method for the biochemical analyzer provided in this embodiment also includes a second wiping step S43. The second wiping step S43 includes controlling the second wiping section 123 of the suction device 120 to wipe the reaction container 300. In this embodiment, the second wiping step S43 can be set between the suction step S30 and the first wiping step S41, or between the first wiping step S41 and the third wiping step S42. The wiping on the first cleaning device 110 and the wiping on the suction device 120 are performed alternately. This allows the second wiping step S43 to be performed in two different rotation cycles within one progressive cycle of the reaction disk 200, along with the suction step S30, the first wiping step S41, or the third wiping step S42. This reduces liquid residue in the reaction container 300 without increasing the number of reaction containers 300 required on the reaction disk 200 or increasing the cleaning time.

[0127] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized by referring to Embodiment 1 and Embodiment 2, and will not be described in detail here.

[0128] Example 4:

[0129] The main difference between the cleaning system 100 and the biochemical analyzer provided in this embodiment and those in Embodiments 1, 2, and 3 lies in the arrangement of the wiping section. Specifically, in Embodiment 1, only the first wiping section 113 is provided on the first cleaning device 110, and no wiping section is provided on the suction device 120; in Embodiments 2 and 3, the first wiping section 113 is provided on the first cleaning device 110, and a second wiping section 123 is provided on the suction device 120; while in this embodiment, only the second wiping section 123 is provided on the suction device 120, and no wiping section is provided on the first cleaning device 110. Since this embodiment can also meet the design requirement that the wiping section and the suction section 122 are independent of each other, the positioning accuracy requirements of the first cleaning device 110, the suction device 120, and the reaction plate 200 can be reduced while ensuring the stability of the liquid residue in the reaction container 300.

[0130] Specifically, in this embodiment, the wiping part includes at least one second wiping part 123. The second wiping part 123 is mounted on the second lifting drive mechanism 121 and is driven by the second lifting drive mechanism 121 to perform upward and downward movements. The arrangement of the second wiping part 123 can be optimized by referring to the second wiping part 123 in Embodiments 2 and 3, and will not be described in detail here.

[0131] The main difference between the control method of the biochemical analyzer provided in this embodiment and that in embodiments two and three is that the wiping step S40 in the control method of the biochemical analyzer provided in this embodiment does not include the first wiping step S41 and the third wiping step S42, but only includes the second wiping step S43. That is, in this embodiment, after the reaction vessel 300 completes the vacuuming step S30, it performs the second wiping step S43 at least once.

[0132] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized by referring to Embodiment 1, Embodiment 2, and Embodiment 3, and will not be described in detail here.

[0133] Example 5:

[0134] Reference Figure 1 , Figure 4 and Figure 6-10 As shown, the main difference between the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment and those in embodiments one to four lies in the arrangement of the wiping section. Specifically, in embodiments one to four, the wiping section includes a first wiping section 113 disposed on the first cleaning device 110 and / or a second wiping section 123 disposed on the suction device 120; while in this embodiment, the wiping section includes a third wiping section 132 disposed on a separate second wiping device 130.

[0135] Specifically, in this embodiment, the second wiping device 130, the first cleaning device 110, and the vacuuming device 120 are three independent devices. The second wiping device 130 includes a fourth lifting drive mechanism 131 and at least one third wiping part 132 for wiping the liquid inside the reaction vessel 300. The third wiping part 132 is driven by the fourth lifting drive mechanism 131 to move up and down. The fourth lifting drive mechanism 131 is independent of the first cleaning device 110 and the vacuuming device 120. The third wiping part 132 is independent of the vacuuming part 122. The first lifting drive mechanism 111, the second lifting drive mechanism 121, and the fourth lifting drive mechanism 131 are independently configured. The third wiping part 132 has a similar function to the first wiping part 113112 in Embodiment 1, except that in this embodiment, the first wiping part 113 (i.e., the third wiping part 132) is driven up and down by an independent lifting drive mechanism.

[0136] The third wiping part 132 can be directly mounted on the fourth lifting drive mechanism 131, or indirectly mounted on the fourth lifting drive mechanism 131, as long as the fourth lifting drive mechanism 131 can drive the third wiping part 132 to move upward and downward. The principle of the fourth lifting drive mechanism 131 driving the third wiping part 132 can be referred to the principle of the first lifting drive mechanism 111 driving the first wiping part 113 in Embodiment 1, and will not be described in detail here.

[0137] The main difference between the control method of the biochemical analyzer provided in this embodiment and that in embodiments two and three is that the wiping step S40 in the control method of the biochemical analyzer provided in this embodiment includes a fourth wiping step S40. After the reaction vessel 300 completes the vacuuming step S30, it performs at least one fourth wiping step S40.

[0138] It should be noted that, as one implementation, a wiping part may be provided only on the wiping device 130, without providing wiping parts on the first cleaning device 110 and the vacuuming device 120, that is, the wiping part may only include the third wiping part 132; as another implementation, a wiping part may be provided on the wiping device 130, and a wiping part may also be provided on at least one of the first cleaning device 110 and the vacuuming device 120, that is, the wiping part includes the third wiping part 132, and the wiping part also includes at least one of the first wiping part 113 provided on the first cleaning device 110 and the second wiping part 123 provided on the vacuuming device 120.

[0139] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized by referring to any one of embodiments one to four, and will not be described in detail here.

[0140] Example 6:

[0141] Reference Figure 1 , Figure 4 , Figure 6 and Figure 11 As shown, the main difference between the cleaning system 100 and the biochemical analyzer provided in this embodiment and those in embodiments one to five lies in whether or not a cleaning section is provided on the suction device 120. Specifically, in embodiments one to five, no cleaning section is provided on the suction device 120; while in this embodiment, based on any one of embodiments one to five, a cleaning section is provided on the suction device 120.

[0142] Specifically, the vacuum suction device 120 further includes at least one second cleaning section 124 for injecting liquid to clean the reaction vessel 300. The distance between each second cleaning section 124 and a first cleaning section 112 in the rotation direction M of the reaction disk 200 is an integer multiple of the distance the reaction vessel 300 travels in one rotation cycle of the reaction disk 200. The second cleaning section 124 is driven by the second lifting drive mechanism 121 to move upward and downward. The second cleaning section 124 can be directly installed on the second lifting drive mechanism 121 or indirectly installed on the second lifting drive mechanism 121, as long as it can ensure that the second lifting drive mechanism 121 can drive the second cleaning section 124 to move upward and downward. The principle of the second lifting drive mechanism 121 driving the second cleaning section 124 can be referred to the principle of the second lifting drive mechanism 121 driving the vacuum suction section 122, and will not be described in detail here.

[0143] Preferably, during the process of the reaction disk 200 driving the reaction vessel 300 to rotate from one first cleaning section 112 to one progressive cycle, the second cleaning section 124 is disposed between the first cleaning section 112 and the suction section 122 along the rotation direction M of the reaction disk 200, that is, the second cleaning section 124 is located upstream of the suction section 122. Of course, in specific applications, as an alternative embodiment, the suction section 122 can also be disposed between the first cleaning section 112 and the second cleaning section 124 along the rotation direction M of the reaction disk 200, that is, the second cleaning section 124 can also be disposed downstream of the suction section 122.

[0144] Preferably, the second cleaning section 124 includes a second suction section 1241 for suctioning liquid from the reaction vessel 300 and a second injection section 1242 for injecting cleaning liquid into the reaction vessel 300. The second injection section 1242 and the second suction section 1241 are arranged side by side, and the distance between the second injection section 1242 and the second suction section 1241 is less than the outer diameter of the reaction vessel 300. Specifically, the second injection section 1242 and the second suction section 1241 can be arranged side by side in any direction. For example, they can be arranged side by side in the radial direction, in the circumferential direction, or along a direction at a certain angle to the radial direction, i.e., the line connecting the two forms a certain angle with the radial direction. In addition, the side-by-side arrangement of the second injection section 1242 and the second suction section 1241 can be a close-fitting side-by-side arrangement or a spaced-out side-by-side arrangement. The second cleaning section 124 is a dual-channel structure that simultaneously has the functions of suction and injection. When the second cleaning unit 124 performs liquid injection cleaning on the reaction vessel 300, it first draws the liquid in the reaction vessel 300 through the second liquid suction unit 1241, and then injects the cleaning liquid into the reaction vessel 300 through the second liquid injection unit 1242, thereby completing one liquid injection cleaning of the reaction vessel 300 by the second cleaning unit 124.

[0145] The difference between the control method of the biochemical analyzer provided in this embodiment and any one of embodiments one to five is that the control method of the biochemical analyzer provided in this embodiment further includes a second cleaning step before the water blank detection step S20. The second cleaning step includes: injecting liquid to clean the reaction vessel 300 through the second cleaning section 124 of the suction device 120.

[0146] Specifically, the first cleaning step S10 includes at least two sub-steps (one cleaning agent cleaning step S11 and one water cleaning step S12 are each a sub-step). The second cleaning step is located between any two sub-steps. For example, the second cleaning step can be set between the two cleaning agent cleaning steps S11 of the first cleaning step S10; or, the second cleaning step can also be set between the two water cleaning steps S12 of the first cleaning step S10; or, the second cleaning step can also be set between the cleaning agent cleaning step S11 and the water cleaning step S12 of the first cleaning step S10. Alternatively, as an alternative implementation, the second cleaning step can also be set between the first cleaning step S10 and the water blank detection step S20, that is, after the first cleaning step S10 completes the last liquid injection cleaning, the second cleaning step is performed, and then the water blank detection step S20 is performed.

[0147] For situations where more cleaning cycles are required without sacrificing the operating cycle, the second cleaning unit 124 and the second cleaning step can effectively improve the efficiency of the biochemical analyzer.

[0148] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized by referring to any one of embodiments one to five, and will not be described in detail here.

[0149] Example 7:

[0150] Reference Figure 1 , Figure 4 , Figure 6 and Figure 12As shown, the main difference between the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment and those in embodiments one to six lies in the number of suction units 122. Specifically, in embodiments one to six, the suction device 120 includes only one suction unit 122 in the rotation direction M of the reaction disk 200 (i.e., the circumferential direction of the reaction disk 200); while in this embodiment, the suction device 120 includes at least two suction units 122 sequentially distributed along the rotation direction M of the reaction disk 200. During the process of the reaction disk 200 driving the reaction container 300 to rotate from a first cleaning unit 112 for one progressive cycle, the distance between each two adjacent suction units 122 in the rotation direction of the reaction disk 200 is equal to an integer multiple of the distance the reaction container 300 moves in one rotation cycle of the reaction disk 200.

[0151] In a preferred embodiment of this invention, the vacuum device 120 includes two vacuum sections 122 sequentially distributed along the rotation direction M of the reaction disk 200. Thus, after the reaction container 300 completes liquid injection cleaning and water blank detection, it undergoes two vacuuming steps S30 before entering the wiping step S40. This further reduces the amount of liquid remaining in the reaction container 300, thereby improving the stability of liquid residue within the reaction container 300. Furthermore, the two circumferentially distributed vacuum sections 122 do not significantly increase costs, resulting in good overall performance. Of course, in specific applications, the number of vacuum sections 122 sequentially distributed along the rotation direction M of the reaction disk 200 is not limited to two; for example, it can also be three or four.

[0152] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized by referring to any one of embodiments one to six, and will not be described in detail here.

[0153] Example 8:

[0154] The main difference between the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment and those in embodiments one to seven lies in whether the first cleaning section 112 and the suction section 122 are set on the same device: In embodiments one to seven, the first cleaning section 112 and the suction section 122 are respectively set on two independent devices (i.e., the first cleaning device 110 and the suction device 120), and are driven by two independent lifting drive mechanisms respectively; while in this embodiment, the first cleaning section 112 and the suction section 122 are set on the same device, and are driven by the same lifting drive mechanism.

[0155] Specifically, in this embodiment, the first cleaning device 110, the first wiping device, and the vacuuming device 120 are integrated, that is, the cleaning system 100 includes a second cleaning device (not shown in the figure). The second cleaning device includes a third lifting drive mechanism, an idle position 114, at least one first cleaning part 112, at least one vacuuming part 122, and at least one first wiping part 113. The third lifting drive mechanism is used to drive the first cleaning part 112 and the vacuuming part 122 to move up and down.

[0156] By adopting the solution of this embodiment, as long as the following conditions are met: during the process of the reaction disk 200 driving the reaction container 300 to rotate from the first cleaning section 112 to one progressive cycle, the distance between the suction section 122 and the first wiping section 113 in the rotation direction of the reaction disk 200 is equal to an integer multiple of the distance the reaction container 300 moves in one rotation cycle of the reaction disk 200, and less than the distance the reaction container 300 moves in one progressive cycle of the reaction disk 200, the suction operation of a reaction container 300 and the water blank detection or wiping operation of the reaction container 300 can be performed in different rotation cycles of the same progressive cycle. Thus, without increasing the number of reaction containers 300 required on the reaction disk 200 or increasing the progressive cycle and cleaning time, the liquid suction treatment after liquid injection and cleaning of the reaction container 300 can be achieved, so that the setting of the suction section 122 will not reduce the utilization efficiency of the reaction container 300.

[0157] Apart from the differences mentioned above, the other parts of the cleaning system 100, biochemical analyzer, and control method of the biochemical analyzer provided in this embodiment can be optimized by referring to any one of embodiments one to seven, and will not be described in detail here.

[0158] The above description is merely a preferred embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structural transformations made using the contents of the present invention's specification and drawings under the inventive concept of the present invention, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present invention.

Claims

1. A biochemical analyzer characterized by comprising: It includes a reaction plate, a rotary drive device, a sample dispensing device, a reagent dispensing device, a stirring device, a detection device, and a cleaning system; The reaction disk has multiple circumferentially distributed receiving slots for placing reaction containers. The reaction disk has a rotation cycle and a progressive cycle. The rotation cycle is when the reaction disk completes one rotation and one stop. After one rotation cycle, the reaction container moves at least two container positions along the rotation direction of the reaction disk. The progressive cycle includes at least two rotation cycles. After one progressive cycle, the distance the reaction container moves relative to the reaction disk circumferentially is equal to the distance between two adjacent reaction containers on the circumferential direction of the reaction disk. The rotary drive device is used to drive the reaction disk to rotate. The cleaning system, the sample dispensing device, the reagent dispensing device, the stirring device, and the detection device are distributed along the circumference of the reaction plate; The cleaning system includes: At least one first cleaning unit, the first cleaning unit being used to perform liquid injection cleaning on the reaction vessel on the reaction plate; At least one suction section is provided, which is used to suction the liquid remaining in the reaction vessel after it has been cleaned by the first cleaning section. At least one first wiping section, the first wiping section and the suction section are independently arranged, and the first wiping section is used to wipe the liquid remaining in the reaction vessel after the liquid is sucked by the suction section; During the process of the reaction disk driving the reaction container to rotate from one first cleaning section to one progressive cycle, the suction section is located between the first cleaning section and the first wiping section along the rotation direction of the reaction disk; and the distance between the suction section and the first wiping section closest to the first cleaning section in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction container moves in one rotation cycle of the reaction disk, and less than the distance the reaction container moves in one progressive cycle of the reaction disk, where the integer multiple is a value greater than or equal to one, so that the suction operation of a reaction container and the wiping operation of the reaction container are performed in different rotation cycles of the same progressive cycle, thereby performing the suction operation and wiping operation of the reaction container sequentially; The detection device is used to perform water blank detection on the reaction vessel after it has been cleaned by the first cleaning section and before the liquid is drawn off by the vacuum section.

2. The biochemical analyzer as described in claim 1, characterized in that: In each of the first cleaning sections and each of the first wiping sections, the distance between the closest first cleaning section and the closest first wiping section is equal to twice the distance that the reaction vessel moves circumferentially relative to the reaction disk over one of the progressive cycles.

3. The biochemical analyzer as described in claim 2, characterized in that: In each of the first cleaning sections and each of the first wiping sections, an idle position is formed at the midpoint between the closest first cleaning section and the first wiping section. The idle position is used to allow the cleaning system to reserve the duration of one progressive cycle for the reaction vessel after it has been cleaned by the first cleaning section, so as to perform water blank detection. The detection device is used to perform sample detection on the reaction liquid made of sample and reagent in the reaction vessel; and is used to perform water blank detection on the reaction vessel after it has been cleaned by the first cleaning section and passed through the idle position before the liquid is aspirated by the vacuum section.

4. A biochemical analyzer, characterized in that, It includes a reaction plate, a rotary drive device, a sample dispensing device, a reagent dispensing device, a stirring device, a detection device, and a cleaning system; The reaction disk has multiple circumferentially distributed receiving slots for placing reaction containers. The reaction disk has a rotation cycle and a progressive cycle. The rotation cycle is when the reaction disk completes one rotation and one stop. After one rotation cycle, the reaction container moves at least two container positions along the rotation direction of the reaction disk. The progressive cycle includes at least two rotation cycles. After one progressive cycle, the distance the reaction container moves relative to the reaction disk circumferentially is equal to the distance between two adjacent reaction containers on the circumferential direction of the reaction disk. The rotary drive device is used to drive the reaction disk to rotate. The cleaning system, the sample dispensing device, the reagent dispensing device, the stirring device, and the detection device are distributed along the circumference of the reaction plate; The cleaning system includes: At least one first cleaning unit, the first cleaning unit being used to perform liquid injection cleaning on the reaction vessel on the reaction plate; An idle position is provided for the cleaning system to reserve the duration of one progressive cycle for the reaction vessel after it has been cleaned by the first cleaning unit, so as to perform water blank detection; the distance between the idle position and the nearest first cleaning unit is equal to the distance that the reaction vessel moves circumferentially relative to the reaction plate during one progressive cycle. At least one suction section is provided for suctioning the liquid remaining in the reaction vessel after it has been cleaned by the first cleaning section and passed through the idle position. The detection device is used to perform water blank detection on the reaction vessel after it has been cleaned by the first cleaning section and passed through the idle position before the liquid is drawn in the suction section. During the process of the reaction disk driving the reaction vessel to rotate from the idle position for one progressive cycle, the first cleaning part is located between the idle position and the suction part along the rotation direction of the reaction disk, and the distance between the idle position and the suction part in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction vessel moves in one rotation cycle of the reaction disk, and less than the distance the reaction vessel moves in one progressive cycle of the reaction disk, where the integer multiple is a value greater than or equal to one; so that the water blank detection of a reaction vessel and the suction operation of the reaction vessel are performed in different rotation cycles of the same progressive cycle, thereby sequentially performing water blank detection and suction operation on the reaction vessel.

5. The biochemical analyzer as described in claim 4, characterized in that: The cleaning system further includes at least one first wiping section, which is independently arranged from the suction section, and the first wiping section is used to wipe away the liquid remaining in the reaction vessel after the liquid is sucked by the suction section.

6. The biochemical analyzer as described in claim 5, characterized in that: During the process of the reaction disk driving the reaction vessel to rotate from one first cleaning section to one progressive cycle, the suction section is located between the first cleaning section and the first wiping section along the rotation direction of the reaction disk; the distance between the suction section and the first wiping section closest to the first cleaning section in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction vessel moves in one rotation cycle of the reaction disk, and less than the distance the reaction vessel moves in one progressive cycle of the reaction disk, where the integer multiple is a value greater than or equal to one, so that the water blank detection, suction operation and wiping operation performed sequentially on one reaction vessel can be performed in different rotation cycles of the same progressive cycle.

7. The biochemical analyzer according to any one of claims 1 to 6, characterized in that: The progressive period includes less than or equal to ten of the rotation periods; or... The progressive cycle includes five or fewer rotation cycles.

8. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The cleaning system also includes: A first lifting drive mechanism is used to drive the first cleaning part and the first wiping part to move up and down. The second lifting drive mechanism is used to drive the suction part to move upward and downward. The first lifting drive mechanism and the second lifting drive mechanism are set independently of each other.

9. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The cleaning system also includes: A first lifting drive mechanism is used to drive the first cleaning unit to perform upward and downward movements. The second lifting drive mechanism is used to drive the suction part and the first wiping part to move up and down; The first lifting drive mechanism and the second lifting drive mechanism are set independently of each other.

10. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The cleaning system further includes a third lifting drive mechanism, which drives the first cleaning unit, the first wiping unit, and the suction unit to move upward and downward.

11. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The cleaning system further includes: a first lifting drive mechanism, which is used to drive the first cleaning unit to perform upward and downward movements; The second lifting drive mechanism is used to drive the suction part to move upward and downward. The fourth lifting drive mechanism is used to drive the first wiping part to move up and down; The first lifting drive mechanism, the second lifting drive mechanism, and the fourth lifting drive mechanism are independently configured.

12. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The cleaning system further includes at least one second wiping section, which is used to wipe the inside of the reaction vessel after it has been wiped by one of the first wiping sections. During the process of the reaction disk rotating the reaction vessel from one of the first cleaning sections in one progressive cycle, the second wiping section is positioned between the first cleaning section and the suction section along the rotation direction of the reaction disk. Among the suction sections and the second wiping sections, the distance between the closest suction section and the second wiping section is equal to the distance the reaction vessel moves circumferentially relative to the reaction disk during one progressive cycle; or... The cleaning system further includes at least one second wiping section, which is used to wipe the reaction vessel after it has been sucked up by the suction section and before or after being wiped by the first wiping section. During the process of the reaction disk driving the reaction vessel to rotate from one of the first cleaning sections for one progressive cycle, the second wiping section is located between the suction section and the first wiping section along the rotation direction of the reaction disk. The distance between the second wiping section and the suction section or one of the first wiping sections in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction vessel moves in one rotation cycle of the reaction disk.

13. The biochemical analyzer according to any one of claims 1 to 6, characterized in that: The cleaning system further includes at least one second cleaning section for injecting liquid to clean the reaction vessel. The distance between each second cleaning section and one of the first cleaning sections in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction vessel travels in one rotation cycle of the reaction disk.

14. The biochemical analyzer according to any one of claims 1 to 6, characterized in that: The cleaning system includes at least two suction sections arranged sequentially along the rotation direction of the reaction disk. During the process of the reaction disk driving the reaction container to rotate from one first cleaning section to one progressive cycle, the distance between each two adjacent suction sections in the rotation direction of the reaction disk is equal to an integer multiple of the distance the reaction container moves in one rotation cycle of the reaction disk.

15. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The receiving slot includes a first receiving slot and a second receiving slot. A plurality of first receiving slots are distributed along a first circumference on the reaction disk, and a plurality of second receiving slots are distributed along a second circumference on the reaction disk. The second circumference is located on the outer circumference of the first circumference. The cleaning system includes at least one set of first cleaning units, at least one set of vacuum units, and at least one set of first wiping units. Each set of first cleaning units includes two first cleaning units that are sequentially distributed along the radial direction of the reaction plate and correspond to the positions of the first receiving groove and the second receiving groove, respectively. Each group of suction sections includes two suction sections that are sequentially distributed along the radial direction of the reaction disk and correspond to the positions of the first receiving groove and the second receiving groove, respectively; Each group of first wiping sections includes two first wiping sections that are sequentially distributed along the radial direction of the reaction disk and correspond to the positions of the first receiving groove and the second receiving groove, respectively.

16. The biochemical analyzer according to any one of claims 1 to 6, characterized in that: The first cleaning section includes a first cleaning agent cleaning section and a first clean water cleaning section. The cleaning system includes at least one first cleaning agent cleaning section and at least one first clean water cleaning section. The first cleaning agent cleaning section is located between the first clean water cleaning section and the suction section along the rotation direction of the reaction plate. The first cleaning agent cleaning section includes a first suction section for suctioning liquid in the reaction container and a first injection section for injecting cleaning agent into the reaction container. The first injection section and the first suction section are arranged side by side, and the distance between the first injection section and the first suction section is less than the outer diameter of the reaction container. The first clean water cleaning unit includes a third liquid suction unit for suctioning liquid from the reaction vessel and a third liquid injection unit for injecting clean water into the reaction vessel. The third liquid injection unit and the third liquid suction unit are arranged side by side, and the distance between the third liquid injection unit and the third liquid suction unit is less than the outer diameter of the reaction vessel.

17. The biochemical analyzer as described in any one of claims 1 to 3, or 5 or 6, characterized in that: The first wiping part is a suction needle with a wiping head at one end or a suction tube with a wiping head at one end.

18. The biochemical analyzer according to any one of claims 1 to 6, characterized in that: In two adjacent progressive cycles, the same reaction vessel moves a distance equal to the distance between two adjacent reaction vessels around the reaction disk, and the direction of movement is opposite to the direction of rotation of the reaction disk.

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