Micro-nucleic acid vacuum centrifugal concentration device and micro-nucleic acid solution concentration method
CN114657048BActive Publication Date: 2026-06-23JIANGSU JIZHI CLINIC CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- JIANGSU JIZHI CLINIC CO LTD
- Filing Date
- 2022-04-15
- Publication Date
- 2026-06-23
AI Technical Summary
Technical Problem
[0007]本发明提供一种微量核酸真空离心浓缩装置与微量核酸溶液浓缩方法,用以解决或改善现有技术存在的至少一种技术问题,以实现在一定程度上消除浓缩过程中核酸样本间的交叉污染风险,获得高浓度的核酸溶液
Benefits of technology
[0024] Wherein, the first duration is longer than the second duration, the volume of the nucleic acid solution to be concentrated is less than or equal to 50 μl, the initial concentration is less than 1-5 ng/μl, the volume of the concentrated nucleic acid solution is 7-10 μl, and the room temperature is 25℃-37℃.
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Figure CN114657048B_ABST
Abstract
The present application provides a kind of trace nucleic acid vacuum centrifugal concentration device and trace nucleic acid solution concentration method, trace nucleic acid vacuum centrifugal concentration device includes vacuum pan, aerosol suction accessory, centrifugal mechanism and vacuumizing mechanism;Vacuum pan shell wall is equipped with air extraction hole, air extraction hole is communicated with vacuumizing mechanism, and vacuumizing mechanism is used to carry out vacuumizing treatment to the internal environment of vacuum pan;Centrifugal mechanism includes centrifugal rotor, and centrifugal rotor is rotatably arranged in vacuum pan, and centrifugal rotor is used to install trace centrifugal test tube, to carry out centrifugation to trace centrifugal test tube in trace nucleic acid sample;Aerosol suction accessory is arranged in air extraction hole, and aerosol suction accessory is used to adsorb nucleic acid aerosol in the internal environment of vacuum pan.The present application prevents trace nucleic acid sample transition centrifugation loss, prevents nucleic acid sample aerosol cross contamination situation, retains the physicochemical properties of nucleic acid, and obtains high concentration trace nucleic acid solution sample meeting human and paraffin sample gene library quality standard.
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