An ultrasonic catheter for delivering therapeutic compounds

Abstract

This invention relates to an ultrasonic catheter for delivering therapeutic compounds, comprising a main drive mechanism, a delivery mechanism, and an anti-backflow mechanism. The delivery mechanism is located at the bottom of the main drive mechanism, and the anti-backflow mechanism is located in the middle of the delivery mechanism. Three sets of transversely evenly arranged access tubes are fixedly connected to the left side of the top wall of the mounting shell. Under the reverse action of the compression of the retaining spring at the bottom of the retaining spring, the first and second conical blocking blocks return to close contact with the top wall inside the mounting cylinder and the bottom wall of the limiting ring, automatically shutting off the delivery capacity of the ultrasonic bend tube to prevent the backflow of compounds and patient internal fluids. The left and right movement of the blocking strip allows the docking holes installed on the top of the limiting block to connect sequentially with the delivery chute. The access tubes connected to the top of the three sets of docking holes can connect sequentially or simultaneously with the delivery chute, realizing the single or multiple simultaneous delivery of therapeutic compounds.

Description

Technical Field

[0001] This invention relates to the field of ultrasound therapy technology, and more particularly to an ultrasound catheter for delivering therapeutic compounds. Background Technology

[0002] Ultrasound medicine is a discipline formed by combining ultrasound science with medicine or applying ultrasound technology to various departments of medicine. It mainly includes the research and application of ultrasound in basic medicine, clinical medicine, hygiene, and other medical fields. This discipline is constantly developing with the advancement of ultrasound detection and processing. For example, the achievements of ultrasound imaging technology have been quickly applied to ultrasound medicine. In medicine, ultrasound energy is often used to enhance the delivery and / or effects of therapeutic compounds. For example, in the context of treating vascular occlusion, ultrasound energy has been shown to increase enzyme-mediated thrombolysis by enhancing the delivery of thrombolytic drugs into the thrombus. Thrombolytic drugs dissolve thrombi by degrading the fibrin that forms the thrombus. When ultrasound energy is present in the thrombus, the thrombolytic activity of the agent is enhanced. Ultrasound catheters are often used in the treatment of patients.

[0003] In the process of using ultrasonic therapeutic compound delivery catheters, the existing ultrasonic therapeutic compound delivery catheters on the market often have two drawbacks. First, the existing ultrasonic therapeutic compound delivery catheters often cannot achieve the ability to deliver different compounds individually or in combination. Second, the existing ultrasonic therapeutic compound delivery catheters often experience internal backflow after use, causing secondary damage to equipment and personnel. Summary of the Invention

[0004] The purpose of this invention is to overcome the shortcomings of the prior art, adapt to practical needs, and provide an ultrasonic catheter for delivering therapeutic compounds, thereby solving the technical problems of existing ultrasonic catheters being unable to deliver different compounds individually or in free combination and being unable to effectively suppress backflow.

[0005] To achieve the objectives of this invention, the technical solution adopted is as follows: Design an ultrasonic catheter for delivering therapeutic compounds, including a main drive mechanism, a delivery mechanism and an anti-backflow mechanism, wherein the delivery mechanism is provided at the bottom of the main drive mechanism and the anti-backflow mechanism is provided in the middle of the delivery mechanism.

[0006] Preferably, the main drive mechanism includes a mounting shell, an inlet pipe, a limiting block, a docking hole, an internal threaded hole, a conveying chute, a limiting chute, a rotating shaft, a bolt, a blocking strip, a limiting slider, and a miniature bearing. Three sets of horizontally evenly arranged inlet pipes are fixedly connected to the left side of the top wall of the mounting shell. The limiting block is fixedly connected to the left side of the interior of the mounting shell. A conveying chute is provided in the upper center of the interior of the limiting block, and a limiting chute is provided in the lower center of the interior of the limiting block. Three sets of horizontally evenly arranged docking holes are provided on the bottom wall of the limiting block. A miniature bearing is fixedly connected to the lower center of the left side wall of the mounting shell. A rotating shaft is fixedly connected to the inner ring of the miniature bearing. A bolt is fixedly connected to the right end of the rotating shaft. A blocking strip slides horizontally inside the conveying chute. A limiting slider is fixedly connected to the left side of the bottom wall of the blocking strip. The limiting slider slides horizontally inside the limiting chute. An internal threaded hole is provided on the left side of the inside of the limiting slider. The limiting slider is threadedly connected to the bolt through the internal threaded hole. A square one-way pipe is fixedly connected to the right end of the conveying chute.

[0007] Preferably, the conveying mechanism includes a handle shell, a main conveying pipe, an ultrasonic bend, an arc-shaped end, an outer sheath, a waterproof layer, a sound insulation layer, and a conveying metal sheet. The handle shell is fixedly connected to the right side of the bottom wall of the mounting shell. The main conveying pipe is fixedly connected to the inside of the handle shell and extends longitudinally through the handle shell. A square one-way pipe is fixedly connected to the top of the main conveying pipe, and an ultrasonic bend is fixedly connected to the bottom of the main conveying pipe. An outer sheath is provided on the outer wall of the ultrasonic bend, a waterproof layer is provided on the inner wall of the outer sheath, a sound insulation layer is provided on the inner wall of the waterproof layer, and a conveying metal sheet is provided on the inner wall of the sound insulation layer.

[0008] Preferably, the anti-backflow mechanism includes an installation cylinder, a limiting ring, a first conical blocking block, a retaining spring, a second conical blocking block, and a fastening rod. The installation cylinder is fixedly connected to the upper part of the ultrasonic bend. The limiting ring is fixedly connected to the center of the inner side wall of the installation cylinder. A fastening rod is provided at the center of the inner side wall of the limiting ring. The first conical blocking block is fixedly connected to the top of the fastening rod, and the second conical blocking block is fixedly connected to the bottom of the fastening rod. A retaining spring is fixedly connected between the bottom wall of the first conical blocking block and the top wall of the limiting ring.

[0009] Preferably, the top ends of the three sets of access pipes are respectively engaged with a set of injection bends, and the top ends of the three sets of injection bends are respectively fixedly connected to a set of docking ends.

[0010] Preferably, the miniature bearing extends laterally through the left side wall of the mounting housing and into the interior of the mounting housing, the rotating shaft extends laterally through the miniature bearing and into the interior of the mounting housing, and the three sets of docking holes extend longitudinally through the bottom wall of the limiting block and into the conveying chute.

[0011] Preferably, the main delivery pipe extends longitudinally through the bottom wall of the square unidirectional pipe and into the interior of the square unidirectional pipe, and the bottom end of the ultrasonic bend is fixedly connected to the arc-shaped end.

[0012] Preferably, the outer layer is made of medical-grade PVC, the waterproof layer is made of thermoplastic polyurethane elastomer rubber, the sound insulation layer is made of foamed sponge, and the conveying metal sheet is made of copper.

[0013] The beneficial effects of this invention are as follows: 1. This invention involves manually rotating a rotating shaft installed on the left side of the mounting housing beforehand. The shaft rotates along a miniature bearing inside the mounting housing, causing a bolt installed on its right end to rotate as well. After the bolt rotates, a limiting slider connected to the limiting slider via an internal threaded hole slides left and right within a limiting groove on the limiting block. This left and right movement of the limiting slider then causes a top-fixed blocking strip to move left and right within a delivery groove on the limiting block. The left and right movement of the blocking strip allows the docking holes on the top of the limiting block to connect sequentially with the delivery groove. The access pipes connected to the tops of the three sets of docking holes can connect sequentially or simultaneously with the delivery groove, enabling the delivery of one or more therapeutic compounds simultaneously.

[0014] 2. In this invention, when the compound enters the mounting cylinder, the impact of the compound causes the first conical blocking block and the fastening rod fixed at the bottom of the first conical blocking block, as well as the second conical blocking block, to descend. As the first and second conical blocking blocks descend, they disengage from the top wall inside the mounting cylinder and the bottom wall of the limiting ring, respectively. Furthermore, the retaining spring installed at the bottom of the retaining spring is compressed, allowing the compound to continue to be delivered through the through hole in the center of the limiting ring. Finally, it is delivered into the patient's body through the ultrasonic bend and the arc-shaped end. When delivery ends, the first and second conical blocking blocks, under the reverse action of the retaining spring compressed at the bottom of the retaining spring, return to close contact with the top wall inside the mounting cylinder and the bottom wall of the limiting ring, and automatically shut down the delivery capacity of the ultrasonic bend, preventing the backflow of the compound and the patient's internal fluids. Attached Figure Description

[0015] Figure 1 This is an isometric schematic diagram of the present invention; Figure 2 This is a three-dimensional cross-sectional view of the structure of the present invention; Figure 3 These are two isometric sectional views of the structure of the present invention. Figure 4 This is a frontal view of the internal structure of the present invention; Figure 5 For the present invention Figure 3 Enlarged view of point A in the middle; Figure 6 For the present invention Figure 4 Enlarged view of point B in the middle; Figure 7This is a schematic diagram of the ultrasonic bending tube structure of the present invention.

[0016] In the diagram: 1. Main drive mechanism; 2. Conveying mechanism; 3. Backflow mechanism; 4. Injection bend; 5. Connecting end; 101. Mounting shell; 102. Inlet pipe; 103. Restricting block; 104. Connecting hole; 105. Internal threaded hole; 106. Conveying chute; 107. Restricting chute; 108. Rotating shaft; 109. Bolt; 110. Blocking strip; 111. Restricting slider; 112. Miniature bearing; 113. Square one-way tube; 201. Handle shell; 202. Main conveying pipe; 203. Ultrasonic bend; 204. Arc-shaped end; 205. Outer sheath; 206. Waterproof layer; 207. Sound insulation layer; 208. Conveying metal sheet; 301. Mounting cylinder; 302. Restricting ring; 303. First conical blocking block; 304. Snap ring; 305. Second conical blocking block; 306. Fastening rod. Detailed Implementation

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments: Example 1: An ultrasonic catheter for delivering therapeutic compounds, see [link to example]. Figures 1 to 6 ; An ultrasonic catheter for delivering therapeutic compounds includes a main drive mechanism 1, a delivery mechanism 2, and an anti-backflow mechanism 3. The delivery mechanism 2 is located at the bottom of the main drive mechanism 1, and the anti-backflow mechanism 3 is located in the middle of the delivery mechanism 2.

[0018] Furthermore, the main drive mechanism 1 includes a mounting housing 101, an access pipe 102, a limiting block 103, a mating hole 104, an internal threaded hole 105, a conveying chute 106, a limiting chute 107, a rotating shaft 108, a bolt 109, a blocking strip 110, a limiting slider 111, and a miniature bearing 112. Three sets of horizontally evenly arranged access pipes 102 are fixedly connected to the left side of the top wall of the mounting housing 101. The limiting block 103 is fixedly connected to the left side of the interior of the mounting housing 101. A conveying chute 106 is provided in the upper part of the interior of the limiting block 103, and a limiting chute 107 is provided in the lower part of the interior of the limiting block 103. The bottom wall of block 103 has three sets of evenly arranged transversely arranged mating holes 104. A miniature bearing 112 is fixedly connected to the lower middle part of the left side wall of the mounting shell 101. A rotating shaft 108 is fixedly connected to the inner ring of the miniature bearing 112. A bolt 109 is fixedly connected to the right end of the rotating shaft 108. A blocking strip 110 is transversely slidably connected inside the conveying chute 106. A limiting slider 111 is fixedly connected to the left side of the bottom wall of the blocking strip 110. The limiting slider 111 is transversely slidably connected inside the limiting chute 107. An internal threaded hole 105 is provided on the left side inside the limiting slider 111. The limiting slider 111 is threadedly connected to the bolt 109 through the internal threaded hole 105. 9. A square one-way tube 113 is fixedly connected to the right end of the conveying chute 106. By manually rotating the rotating shaft 108 installed on the left side of the mounting housing 101 beforehand, the rotating shaft 108 rotates along the miniature bearing 112 inside the mounting housing 101. The rotation of the rotating shaft 108 causes the bolt 109 installed on its right end to rotate as well. After the bolt 109 rotates, the limiting slider 111, which is threaded to it through the installed internal thread hole 105, slides left and right inside the limiting chute 107 set in the limiting block 103. The left and right sliding of the limiting slider 111 then drives the blocking strip 110 fixed at the top to move within the limiting block 103. The conveying chute 106 moves left and right inside, and the blocking strip 110 moves left and right so that the docking holes 104 installed on the top of the limiting block 103 can be connected to the conveying chute 106 in sequence. The access pipes 102 connected to the top of the three sets of docking holes 104 can be connected to the conveying chute 106 in sequence or simultaneously, so as to realize the single or multiple simultaneous delivery of therapeutic compounds. The delivered therapeutic compounds are delivered to the main delivery pipe 202 through the conveying chute 106 and the square one-way pipe 113 connected to the right end of the conveying chute 106, and then delivered to the ultrasonic bend pipe 203 and the human body by the delivery mechanism 2.

[0019] Furthermore, the conveying mechanism 2 includes a handle shell 201, a main conveying pipe 202, an ultrasonic bend 203, an arc-shaped end 204, an outer sheath 205, a waterproof layer 206, a sound insulation layer 207, and a conveying metal sheet 208. The handle shell 201 is fixedly connected to the right side of the bottom wall of the mounting shell 101. The longitudinal main conveying pipe 202 is fixedly connected inside the handle shell 201, and the main conveying pipe 202 longitudinally penetrates the handle shell 201. A square one-way pipe 113 is fixedly connected to the top end of the main conveying pipe 202, and the ultrasonic bend 203 is fixedly connected to the bottom end of the main conveying pipe 202. An outer sheath 205 is provided on the outer wall of the ultrasonic bend 203, a waterproof layer 206 is provided on the inner wall of the outer sheath 205, a sound insulation layer 207 is provided on the inner wall of the waterproof layer 206, and a conveying metal sheet 208 is provided on the inner wall of the sound insulation layer 207. During delivery, the first conical blocking block 303 and the second conical blocking block 305, under the reverse action of the snap ring 304 compressed at the bottom of the snap ring 304, return to close contact with the inner top wall of the mounting cylinder 301 and the bottom wall of the limiting ring 302, and automatically shut off the delivery capacity of the ultrasonic bend tube 203 to prevent the backflow of compounds and patient internal fluids. The medical PVC outer layer 205 added to the outside of the ultrasonic bend tube 203 improves the resistance to bending and wear while ensuring medical safety. The waterproof layer 206 made of thermoplastic polyurethane elastomer rubber ensures waterproof and seepage prevention capabilities. The sound insulation layer 207 made of foamed sponge ensures that the low-decibel sound waves generated after the ultrasonic wave propagation ends can be absorbed and alleviated. The copper delivery metal sheet 208 enables the ultrasonic waves to be better transmitted.

[0020] Furthermore, the anti-backflow mechanism 3 includes an installation cylinder 301, a limiting ring 302, a first conical blocking block 303, a retaining spring 304, a second conical blocking block 305, and a fastening rod 306. The installation cylinder 301 is fixedly connected to the upper part of the ultrasonic bend 203. The limiting ring 302 is fixedly connected to the center of the inner wall of the installation cylinder 301. A fastening rod 306 is provided at the center of the inner wall of the limiting ring 302. The top end of the fastening rod 306 is fixedly connected to the first conical blocking block 303, and the bottom end of the fastening rod 306 is fixedly connected to the second conical blocking block 305. A retaining spring 304 is fixedly connected between the bottom wall of the first conical blocking block 303 and the top wall of the limiting ring 302. When the ultrasonic bend passes through... When the backflow mechanism 3 is installed in the upper part of 203, it first enters the installation cylinder 301. The impact of the compound causes the first conical blocking block 303 and the fastening rod 306 fixed at the bottom of the first conical blocking block 303 and the second conical blocking block 305 to descend. When the first conical blocking block 303 and the second conical blocking block 305 descend, they respectively disengage from the contact with the top wall inside the installation cylinder 301 and the bottom wall of the limiting ring 302. Moreover, the retaining spring 304 installed at the bottom of the retaining spring 304 will be compressed, so that the compound can continue to be delivered through the through hole in the center of the limiting ring 302. Finally, it is delivered into the patient's body through the ultrasonic bend tube 203 and the arc-shaped end 204.

[0021] Furthermore, the top ends of the three sets of access tubes 102 are respectively engaged with a set of injection bends 4, and the top ends of the three sets of injection bends 4 are respectively fixedly connected to a set of docking heads 5. The external mechanism is docked through the main drive mechanism 1. The three sets of access tubes 102 added to the top of the mounting shell 101 can all dock with a set of injection bends 4. The docking heads 5 added to the other side of the three sets of injection bends 4 are docked with the external storage device that stores the therapeutic compound.

[0022] Furthermore, the miniature bearing 112 extends laterally through the left side wall of the mounting housing 101 and into the interior of the mounting housing 101, the rotating shaft 108 extends laterally through the miniature bearing 112 and into the interior of the mounting housing 101, and the three sets of docking holes 104 extend longitudinally through the bottom wall of the limiting block 103 and into the conveying chute 106.

[0023] Furthermore, the main delivery pipe 202 extends longitudinally through the bottom wall of the square unidirectional pipe 113 and into the interior of the square unidirectional pipe 113, and the bottom end of the ultrasonic bend 203 is fixedly connected to the arc-shaped end 204.

[0024] Furthermore, the outer layer 205 is made of medical-grade PVC, the waterproof layer 206 is made of thermoplastic polyurethane elastomer rubber, the sound insulation layer 207 is made of foamed sponge, and the conveying metal sheet 208 is made of copper.

[0025] The embodiments disclosed herein are preferred embodiments, but are not limited thereto. Those skilled in the art can readily grasp the spirit of the present invention based on the above embodiments and make different extensions and variations, but as long as they do not depart from the spirit of the present invention, they are all within the protection scope of the present invention.

Claims

1. An ultrasonic catheter for delivering therapeutic compounds, comprising a main drive mechanism, a delivery mechanism, and an anti-backflow mechanism, characterized in that: The main drive mechanism is provided with a conveying mechanism at its bottom, and an anti-backflow mechanism is provided in the middle of the conveying mechanism; The main drive mechanism includes a mounting shell, inlet pipes, a limiting block, mating holes, internal threaded holes, a conveying chute, a limiting chute, a rotating shaft, bolts, a blocking strip, a limiting slider, and a miniature bearing. Three sets of horizontally evenly arranged inlet pipes are fixedly connected to the left side of the top wall of the mounting shell. A limiting block is fixedly connected to the left side of the interior of the mounting shell. A conveying chute is located in the upper center of the interior of the limiting block, and a limiting chute is located in the lower center of the interior of the limiting block. Three sets of horizontally evenly arranged mating holes are located on the bottom wall of the limiting block. A miniature bearing is fixedly connected to the lower center of the left side wall of the mounting shell. A rotating shaft is fixedly connected to the inner ring of the miniature bearing. Bolts are fixedly connected to the right end of the rotating shaft. A blocking strip slides horizontally inside the conveying chute. A blocking strip is fixedly connected to the left side of the bottom wall of the blocking strip. A limiting slider is laterally slidably connected inside a limiting groove. An internally threaded hole is provided on the left side of the limiting slider, through which a bolt is threadedly connected. A square one-way tube is fixedly connected to the right end of the conveying groove. After the bolt is rotated, the limiting slider, threadedly connected to it through the added internally threaded hole, slides left and right inside the limiting groove of the limiting block. This left and right sliding of the limiting slider, in turn, causes a blocking strip fixed at the top to move left and right inside the conveying groove of the limiting block. The left and right movement of the blocking strip causes the docking holes added to the top of the limiting block to connect sequentially with the conveying groove. The access pipes connected to the tops of the three sets of docking holes connect sequentially or simultaneously with the conveying groove, enabling the simultaneous delivery of one or more therapeutic compounds.

2. The ultrasonic catheter for delivering therapeutic compounds as described in claim 1, characterized in that: The conveying mechanism includes a handle shell, a main conveying pipe, an ultrasonic bend, an arc-shaped end, an outer sheath, a waterproof layer, a sound insulation layer, and a conveying metal sheet. The handle shell is fixedly connected to the right side of the bottom wall of the mounting shell. The main conveying pipe is fixedly connected to the inside of the handle shell and extends longitudinally through the handle shell. A square one-way pipe is fixedly connected to the top of the main conveying pipe, and an ultrasonic bend is fixedly connected to the bottom of the main conveying pipe. An outer sheath is provided on the outer wall of the ultrasonic bend, a waterproof layer is provided on the inner wall of the outer sheath, a sound insulation layer is provided on the inner wall of the waterproof layer, and a conveying metal sheet is provided on the inner wall of the sound insulation layer.

3. An ultrasonic catheter for delivering therapeutic compounds as described in claim 2, characterized in that: The anti-backflow mechanism includes an installation cylinder, a limiting ring, a first conical blocking block, a retaining spring, a second conical blocking block, and a fastening rod. The installation cylinder is fixedly connected to the upper part of the ultrasonic bend. The limiting ring is fixedly connected to the center of the inner side wall of the installation cylinder. A fastening rod is provided at the center of the inner side wall of the limiting ring. The top end of the fastening rod is fixedly connected to the first conical blocking block, and the bottom end of the fastening rod is fixedly connected to the second conical blocking block. A retaining spring is fixedly connected between the bottom wall of the first conical blocking block and the top wall of the limiting ring.

4. An ultrasonic catheter for delivering therapeutic compounds as described in claim 1, characterized in that: The top ends of the three sets of access pipes are respectively engaged with a set of injection bends, and the top ends of the three sets of injection bends are respectively fixedly connected to a set of docking ends.

5. An ultrasonic catheter for delivering therapeutic compounds as described in claim 1, characterized in that: The miniature bearing extends laterally through the left side wall of the mounting housing and into the interior of the mounting housing. The rotating shaft extends laterally through the miniature bearing and into the interior of the mounting housing. All three sets of docking holes extend longitudinally through the bottom wall of the limiting block and into the conveying chute.

6. An ultrasonic catheter for delivering therapeutic compounds as described in claim 2, characterized in that: The main delivery pipe runs longitudinally through the bottom wall of the square unidirectional pipe and extends into the interior of the square unidirectional pipe, and the bottom end of the ultrasonic bend is fixedly connected to the arc-shaped end.

7. An ultrasonic catheter for delivering therapeutic compounds as described in claim 2, characterized in that: The outer cladding layer is made of medical-grade PVC, the waterproof layer is made of thermoplastic polyurethane elastomer rubber, the sound insulation layer is made of foamed sponge, and the conveying metal sheet is made of copper.

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