Wireless omnidirectional light stimulator, method and electronic device

Abstract

The application relates to the technical field of biological medical instruments, in particular to a wireless full-view light stimulator, a method and an electronic device, the wireless full-view light stimulator comprising: a contact lens type light stimulation device for contacting a cornea and covering a pupil, and an energy transmission frame glasses; wherein an energy emission coil is arranged in the energy transmission frame glasses, is connected with a power module, emits an electric signal under the power supply of the power module; the contact lens type light stimulation device is provided with an energy receiving coil and a light emitting diode array, the energy receiving coil is used for receiving the electric signal and driving the light emitting diode array to emit light. In this way, the wireless full-view light stimulator can realize wireless transmission of electric energy, improve transmission efficiency, and through the contact lens type light stimulation device directly contacting the cornea and covering the pupil, miniaturization of an electroretinogram detection system is realized, and the activity range of a detected person is not limited.

Description

Technical Field

[0001] This application relates to the field of biomedical instrument technology, and in particular to a wireless full-field photostimulator, method and electronic device. Background Technology

[0002] Electroretinography (ERG) is an important diagnostic tool for retinal-related diseases in ophthalmic electrophysiological examinations. It can accurately characterize the function of important visual source structures such as cone cells and rod cells on the retina by collecting microcurrent signals in the cornea after the eye is stimulated by full-field light. It is of great significance for the diagnosis of various fundus diseases such as retinitis pigmentosa. Among them, the full-field light stimulator is an indispensable component of ERG testing.

[0003] In the prior art, the appearance of a full-field light stimulator is a huge spherical opaque hollow dome. The light source is inside the dome, and the light is reflected from the inner wall of the dome and focused onto an opening on the dome wall. The subject places his eyes against this opening to be stimulated by light for electroretinography (ERG) detection.

[0004] However, the aforementioned photostimulator needs to be connected to a power outlet for power supply, and the signal transmission efficiency is relatively slow. Summary of the Invention

[0005] This application provides a wireless full-field photostimulator, method, and electronic device that can achieve wireless power transmission, improve transmission efficiency, and directly contact the cornea of ​​the eye through a contact lens-type photostimulator, thereby realizing the miniaturization of the electroretinography detection system.

[0006] In a first aspect, this application provides a wireless full-field photostimulator, including: a contact lens photostimulator that contacts the cornea and covers the pupil, and an energy transmission frame eyeglass;

[0007] The energy transmission frame glasses are equipped with an energy transmitting coil for connection to the power module, which transmits electrical signals when powered by the power module.

[0008] The contact lens photostimulation device is equipped with an energy receiving coil and a light-emitting diode array. The energy receiving coil is used to receive the electrical signal and drive the light-emitting diode array to emit light.

[0009] Optionally, the contact lens photostimulation device further includes:

[0010] An impedance matching module is connected in parallel with the energy receiving coil to match the resonant frequencies of the energy transmitting coil and the energy receiving coil.

[0011] Optionally, the power module includes a battery and a circuit board; the battery transmits a power supply signal to the circuit board, and the circuit board generates a sinusoidal voltage signal with a frequency greater than a preset threshold based on the signal;

[0012] The power module is located in the temple of the energy transmission frame glasses, and the energy transmitting coil is located in the frame of the energy transmission frame glasses.

[0013] Optionally, the energy transfer frame glasses further include:

[0014] A focusing lens is used to reflect and focus the light scattered outward by the light-emitting diode array into the pupil.

[0015] Optionally, the contact lens photostimulation device further includes: a ring group; the ring group includes a positive electrode ring and a negative electrode ring, wherein the positive electrode ring and the negative electrode ring have the same center but different radii;

[0016] The positive electrode ring is connected to one end of the energy receiving coil, and the negative electrode ring is connected to the other end of the energy receiving coil;

[0017] The light-emitting diode array includes a plurality of light-emitting diodes disposed between the positive and negative electrode rings of the ring group, with one end of each light-emitting diode connected to the positive electrode ring and the other end connected to the negative electrode ring.

[0018] Optionally, there may be multiple ring groups, with the same center and different radii for each ring group, and a preset distance between adjacent ring groups.

[0019] Optionally, the contact mirror-type photostimulation device further includes: an insulating layer, circuit traces, and through holes;

[0020] The light-emitting diode array, the energy receiving coil, and the ring group are disposed on one side of the insulating layer; the circuit traces and impedance matching module are disposed on the other side of the insulating layer.

[0021] The insulating layer has through holes;

[0022] The circuit traces are used to pass through the vias to connect the LED array, the energy receiving coil, the ring assembly, and the impedance matching module.

[0023] Optionally, the insulating layer and the outer surface of the contact lens photostimulator are both made of flexible polymers, and the outer surface of the contact lens photostimulator is used to directly contact the cornea.

[0024] Secondly, this application also provides a wireless full-field-of-view light stimulation method, applied to a wireless full-field-of-view light stimulator, the wireless full-field-of-view light stimulator comprising a contact lens-type light stimulation device that contacts the cornea and covers the pupil, and an energy transmission frame eyeglass; the method includes:

[0025] The energy transmitting coil in the energy transmission frame glasses receives power from the power module and transmits electrical signals;

[0026] The energy receiving coil in the contact lens photostimulator receives the electrical signal and drives the light-emitting diode array in the contact lens photostimulator to emit light.

[0027] Thirdly, this application also provides an electronic device, comprising: the wireless full-field-of-view photostimulator, electrodes, and amplifier as described in any one of the first aspects;

[0028] The electrode is used to collect the electroretinogram (ERG) signal generated after the retina receives light stimulation from the wireless full-field light stimulator, and to send the ERG signal to the amplifier.

[0029] The amplifier is used to receive the electroretinogram signal and display it on the corresponding ammeter.

[0030] In summary, this application provides a wireless full-field-of-view photostimulator, method, and electronic device. The wireless full-field-of-view photostimulator includes: a contact lens-type photostimulator that contacts the cornea and covers the pupil, and an energy-transmitting eyeglass frame. The energy-transmitting eyeglass frame contains an energy-emitting coil, which can transmit electrical signals when powered by a power module connected to it. Furthermore, the contact lens-type photostimulator includes an energy-receiving coil and a light-emitting diode array. The energy-receiving coil receives the electrical signals transmitted by the energy-emitting coil and drives the light-emitting diode array to emit light based on the electrical signals. Thus, the wireless full-field-of-view photostimulator enables wireless power transmission, improves power transmission efficiency, and, by directly contacting the cornea with the contact lens-type photostimulator, achieves miniaturization of the electroretinography (ERG) detection system, does not restrict the subject's range of motion, and offers high flexibility. Attached Figure Description

[0031] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with this application and, together with the description, serve to explain the principles of this application.

[0032] Figure 1 This is a schematic diagram of an application scenario provided by an embodiment of this application;

[0033] Figure 2 This is a schematic diagram of the structure of the wireless full-field-of-view optical stimulator provided in the embodiments of this application;

[0034] Figure 3A A front view and a side view of the contact mirror-type photostimulation device provided in the embodiments of this application;

[0035] Figure 3B This is an internal structural diagram of the contact mirror-type photostimulation device provided in an embodiment of this application;

[0036] Figure 4 This is a schematic diagram of the operation of the impedance matching module provided in the embodiments of this application;

[0037] Figure 5 This is a schematic diagram of the state of a sinusoidal voltage signal provided in an embodiment of this application;

[0038] Figure 6 This is a schematic diagram of the power module provided in an embodiment of this application;

[0039] Figure 7 This is a schematic diagram of the structure of the condenser lens provided in the embodiments of this application;

[0040] Figure 8 This is a schematic diagram of the structure of a ring assembly provided in an embodiment of this application;

[0041] Figure 9 This is a schematic diagram of another ring assembly provided in an embodiment of this application;

[0042] Figure 10 This is a schematic diagram of the circuit traces and vias provided in the embodiments of this application;

[0043] Figure 11 This is a schematic diagram of the structure of an electronic device provided in an embodiment of this application.

[0044] The accompanying drawings illustrate specific embodiments of this application, which will be described in more detail below. These drawings and descriptions are not intended to limit the scope of the concept in any way, but rather to illustrate the concept of this application to those skilled in the art through reference to particular embodiments. Detailed Implementation

[0045] Exemplary embodiments will now be described in detail, examples of which are illustrated in the accompanying drawings. When the following description relates to the drawings, unless otherwise indicated, the same numbers in different drawings denote the same or similar elements. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with this application. Rather, they are merely examples of apparatuses and methods consistent with some aspects of this application as detailed in the appended claims.

[0046] To facilitate a clear description of the technical solutions in the embodiments of this application, the terms "first" and "second" are used in the embodiments of this application to distinguish identical or similar items with essentially the same function and purpose. For example, "first device" and "second device" are merely used to distinguish different devices and do not limit their order of execution. Those skilled in the art will understand that the terms "first" and "second" do not limit the quantity or execution order, and that "first" and "second" do not necessarily imply that they are different.

[0047] It should be noted that, in this application, the terms "exemplary" or "for example" are used to indicate that something is being described as an example, illustration, or illustration. Any embodiment or design described as "exemplary" or "for example" in this application should not be construed as being more preferred or advantageous than other embodiments or design solutions. Specifically, the use of terms such as "exemplary" or "for example" is intended to present the relevant concepts in a concrete manner.

[0048] In this application, "at least one" means one or more, and "more than one" means two or more. "And / or" describes the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can mean: A alone, A and B simultaneously, or B alone, where A and B can be singular or plural. The character " / " generally indicates that the preceding and following related objects are in an "or" relationship. "At least one of the following" or similar expressions refer to any combination of these items, including any combination of single or plural items. For example, at least one of a, b, or c can mean: a, b, c, ab, ac, bc, or abc, where a, b, and c can be single or multiple.

[0049] The embodiments of this application will now be described in conjunction with the accompanying drawings. Figure 1 This is a schematic diagram illustrating an application scenario provided by an embodiment of this application. The wireless full-field-of-view photostimulator provided in this application can be applied to, for example... Figure 1 The application scenario shown includes a user 101 and a contact lens-type wireless full-field photostimulator 102 for electroretinography (ERG) detection. When the user wants to check for retinal diseases, they can wear the wireless full-field photostimulator 102. After dark adaptation, the user 101 activates the wireless full-field photostimulator 102, which then applies light stimulation to the retina. The light-induced activity of retinal photoreceptor cells leads to an increase in extracellular potassium ion concentration in the outer layer of the retina, generating an electrical signal, i.e., a potential change. This potential change is then transmitted to an amplifier by an electrode placed on the cornea and displayed on a display device such as the amplifier's ammeter or oscilloscope, which is the ERG signal. In this way, it is possible to check for suspicious retinal lesions, detect subclinical lesions, and accurately locate lesions.

[0050] Understandably, full-field photostimulation (FPS) is a widely accepted ophthalmic examination method due to its high diagnostic accuracy and harmlessness. When the retina receives light stimulation, extracellular potassium ions flow into retinal neurons or Müller cells in the inner retinal layer, depolarizing them and generating a longitudinal current. This current can be recorded on the cornea at a distance, becoming an electroretinogram (ERG) signal. The International Society for Clinical Visual Electrophysiology (ISCEV) standards for clinical full-field ERG stipulate that full-field photostimulation should be used to ensure consistent light intensity across all retinal regions, achieving the largest possible stimulation area, the most activated cells, and the largest possible total extracellular current. Therefore, the application of full-field photostimulation has great potential.

[0051] In the existing technology, the appearance of the full-field light stimulator is a huge spherical opaque hollow dome. The light source is inside the dome, and the light is reflected from the inner wall of the dome and focused onto an opening on the dome wall. The subject places his eyes on this opening to achieve full-field light stimulation.

[0052] However, such photostimulators are bulky, heavy, expensive, and have complicated wiring. They need to be connected to a power outlet for power, which restricts the patient's movement. In addition, the signal transmission efficiency is slow, making them inconvenient for home-based testing.

[0053] Therefore, this application provides a wireless full-field photostimulator based on the principle of magnetic resonant coupling, combined with flexible metal / polymer materials related to skin electronics technology, to form a contact lens-type photostimulator. This allows the subject's eyeball to directly contact the contact lens-type photostimulator. By wearing the wireless full-field photostimulator provided by this application on the surface of the eyeball, the power supply module (i.e., the power transmission frame glasses) powers the transmitting coil, which wirelessly provides power to the receiving coil in the contact lens-type photostimulator located on the eye surface, thereby illuminating the light-emitting diode array and achieving full-field photostimulation. Thus, the wireless full-field photostimulator provided by this application has a simple structure, small size and weight, overcomes many shortcomings of clinical instruments, improves the power transmission rate, and makes the miniaturization, wirelessization, and home use of electroretinography (ERG) detection systems possible, with broad application prospects.

[0054] It should be noted that the principle of magnetic coupling resonance is that after impedance matching adjustment, two coils (transmitting coil and receiving coil) can reach the same resonant frequency. At the same resonant frequency, the wireless energy transmission efficiency between the two coils can reach the highest level. Therefore, when an electrical signal with the same resonant frequency is input to the transmitting coil, the receiving coil will receive the same frequency electrical signal with high efficiency. Furthermore, the two ends of the receiving coil are connected to an array of light-emitting diodes, which can then light up the array of light-emitting diodes.

[0055] For example, Figure 2 This is a schematic diagram of the structure of the wireless full-field-of-view photostimulator provided in the embodiments of this application, as shown below. Figure 2 As shown, the wireless full-field photostimulator includes: a contact lens photostimulator 202 that contacts the cornea 203 and covers the pupil, and an energy transmission frame eyeglass 201;

[0056] The energy transmission frame glasses 201 are provided with an energy transmitting coil 204 for connection to the power module 205, and for transmitting electrical signals under the power supply of the power module 205;

[0057] The contact lens photostimulation device 202 is provided with an energy receiving coil 206 and a light-emitting diode array 207. The energy receiving coil 206 is used to receive the electrical signal and drive the light-emitting diode array 207 to emit light.

[0058] The energy transmitting coil 204 is wound inside the frame of the energy transmission frame glasses 201 and connected to the power module 205. It is used to receive the MHz-level sinusoidal burst voltage signal sent by the power module 205. Furthermore, it converts the sinusoidal burst voltage signal into an electrical signal and sends it to the energy receiving coil 206. Based on the principle of magnetic resonance coupling, the energy receiving coil 206 can receive the electrical signal wirelessly transmitted from the energy transmitting coil 204 and rectify the electrical signal, that is, convert the alternating current into direct current, so that the energy receiving coil 206 can light up the light-emitting diode array. This light-emitting diode array can be a micro light-emitting diode array, that is, composed of multiple extremely small light-emitting diodes.

[0059] Optionally, the contact lens-type photostimulation device placed on the ocular surface described in this application is fabricated using flexible metal / polymer materials, realizing a flexible, full-field photostimulator. Figure 3A The front and side views of the contact lens photostimulation device provided in the embodiments of this application are as follows: Figure 3AAs shown, the left side is a front view of the contact lens photostimulator worn on the surface of the eyeball, and the right side is a cross-sectional side view of the contact lens photostimulator worn on the surface of the eyeball. The contact lens photostimulator 202 can directly contact the cornea 203 of the eye because the surface of the contact lens photostimulator 202 is covered by a flexible material 301 with high oxygen permeability. Usually, after the device circuit is processed, the contact lens photostimulator 202 is wrapped in the flexible material 301 by molding injection.

[0060] Specifically, Figure 3B This is an internal structural diagram of the contact lens photostimulation device provided in the embodiments of this application, such as... Figure 3B As shown, the contact lens-type photostimulation device also includes a processing substrate and a flexible insulating layer 302. Devices 303, such as energy receiving coils and light-emitting diode arrays, can be distributed on the processing substrate and the flexible insulating layer 302. The upper and lower sides of the processing substrate and the flexible insulating layer 302 are patterned using micro-electro-mechanical systems (MEMS) processing techniques such as photolithography and etching, so that metal traces such as energy receiving coils can be fixed on the processing substrate and the flexible insulating layer 302. Furthermore, the device 303 and the processing substrate and the flexible insulating layer 302 are encapsulated in a flexible material 301, allowing direct contact with the eye.

[0061] It should be noted that the specific materials of the flexible material 301, the processing substrate, and the flexible insulating layer 302 are not limited in the embodiments of this application. The above is only an example, and it is sufficient to meet the conditions for clinically permissible wear.

[0062] Therefore, this application provides a wireless full-field-of-view photostimulator, which includes: a contact lens-type photostimulator that contacts the cornea and covers the pupil, and an energy transmission frame eyeglass; wherein, the energy transmission frame eyeglass is provided with an energy transmitting coil, which can transmit electrical signals when powered by a power module connected to it; further, the contact lens-type photostimulator is provided with an energy receiving coil and a light-emitting diode array, the energy receiving coil can receive the electrical signals transmitted by the energy transmitting coil, and drive the light-emitting diode array to emit light based on the electrical signals. In this way, the wireless full-field-of-view photostimulator can realize wireless power transmission, improve power transmission efficiency, and achieve miniaturization of the electroretinography detection system by directly contacting the cornea with the contact lens-type photostimulator, without restricting the range of motion of the subject, and with high flexibility.

[0063] Optionally, the contact lens photostimulation device includes:

[0064] An impedance matching module is connected in parallel with the energy receiving coil to match the resonant frequencies of the energy transmitting coil and the energy receiving coil.

[0065] Specifically, Figure 4 This is a schematic diagram of the operation of the impedance matching module provided in the embodiments of this application, as shown below. Figure 4 As shown, the signal generating circuit is connected to the energy transmitting coil 204 to supply power to the energy transmitting coil 204. Furthermore, the energy transmitting coil 204 sends an electrical signal to the energy receiving coil 206. The energy receiving coil 206 is connected in parallel with the impedance matching module 401, which enables the energy receiving coil 206 to achieve the same resonant frequency as the energy transmitting coil 204. Based on the principle of magnetic resonance coupling, the energy receiving coil 206 can receive the electrical signal wirelessly transmitted from the energy transmitting coil 204 with high efficiency, thus accelerating the efficiency of receiving the electrical signal. Furthermore, the energy receiving coil 206 performs rectification, voltage regulation, and other circuit processing on the received electrical signal to light up the light-emitting diode (LED) array 207.

[0066] Therefore, the wireless full-field photostimulator provided in this application embodiment, through the parallel impedance matching module of the energy receiving coil, enables the energy receiving coil to receive the electrical signal wirelessly transmitted from the energy transmitting coil with high efficiency, thereby improving the transmission efficiency.

[0067] Optionally, the power module includes a battery and a circuit board; the battery transmits a power supply signal to the circuit board, and the circuit board generates a sinusoidal voltage signal with a frequency greater than a preset threshold based on the signal;

[0068] The power module is located in the temple of the energy transmission frame glasses, and the energy transmitting coil is located in the frame of the energy transmission frame glasses.

[0069] In this embodiment, the preset threshold may refer to a high-frequency sinusoidal voltage signal, such as a MHz-level sinusoidal burst voltage signal, designed for a wireless full-field photostimulator. The specific parameters are determined according to the clinical requirements of electroretinography (ERG) testing.

[0070] For example, Figure 5 This is a schematic diagram of the state of a sinusoidal voltage signal provided in an embodiment of this application, such as... Figure 5 As shown, the high-frequency sinusoidal modulated pulse signal sent by the power module is used to achieve wireless power transmission.

[0071] It should be noted that the embodiments of this application do not specifically limit the values ​​corresponding to the preset threshold and the preset time.

[0072] Specifically, Figure 6This is a schematic diagram of the power module provided in an embodiment of this application, as shown below. Figure 6 As shown, the power module 205 may include a battery 602 (located behind the circuit board) and a circuit board 601; furthermore, the battery 602 can transmit the power supply signal to the circuit board 601. The power module 205 is located in the temple 603 of the energy transmission frame glasses, while the energy transmitting coil 204 is located in the frame 604 of the energy transmission frame glasses. The power module 205 is connected to the energy transmitting coil 204. The reasonable arrangement of the positions of the energy transmitting coil and the power module saves space and conforms to the structure of the glasses.

[0073] It is understood that the battery 602 can be located anywhere in the temple, such as in front of the circuit board. This application embodiment does not specifically limit this, as long as it can provide power to the circuit board. The figure is only an example.

[0074] Therefore, the wireless full-field photostimulator provided in this application embodiment is based on high-frequency sinusoidal voltage signal for electrical transmission, which improves the transmission success rate. In addition, the positions of the energy emission coil and power module are reasonably arranged, which conforms to the structure of glasses, thereby improving the user experience.

[0075] Optionally, the energy transfer frame glasses include:

[0076] A focusing lens is used to reflect and focus the light scattered outward by the light-emitting diode array into the pupil.

[0077] Specifically, the focusing lens embedded in the frame can have a reflective material coated on the side closest to the eye to gather scattered light towards the pupil, participate in photostimulation, and increase the intensity of the light stimulus. Figure 7 This is a schematic diagram of the structure of the condenser lens provided in the embodiments of this application, such as... Figure 7 As shown, the energy transmission frame glasses 201 have a focusing lens 701 nested inside the frame, which can focus the light scattered to the outside by the contact lens photostimulation device 202 onto the cornea 203, reduce the loss of light scattering, and improve the effect of photostimulation.

[0078] Therefore, the wireless full-field photostimulator provided in this application embodiment utilizes its lens design to focus light, reducing light source waste and making the photostimulation effect of the wireless full-field photostimulator better.

[0079] Optionally, the contact lens photostimulation device includes: a ring group; the ring group includes a positive electrode ring and a negative electrode ring, wherein the positive electrode ring and the negative electrode ring have the same center but different radii;

[0080] The positive electrode ring is connected to one end of the energy receiving coil, and the negative electrode ring is connected to the other end of the energy receiving coil;

[0081] The light-emitting diode array includes a plurality of light-emitting diodes disposed between the positive and negative electrode rings of the ring group, with one end of each light-emitting diode connected to the positive electrode ring and the other end connected to the negative electrode ring.

[0082] Specifically, to ensure sufficient light stimulation enters the pupil, the LED array can be arranged in a circular pattern within the contact lens-type photostimulator, covering the entire pupil. Figure 8 This is a schematic diagram of the structure of a ring assembly provided in an embodiment of this application, as shown below. Figure 8 As shown, the annular group 801 consists of a positive electrode annular group 8011 and a negative electrode annular group 8012. An array of light-emitting diodes (LEDs) 207 is distributed on the annular group 801. The LED array 207 can be distributed as shown in the figure, that is, the LED array 207 includes multiple LEDs. Multiple component pads 802 are distributed on both the positive electrode annular group 8011 and the negative electrode annular group 8012. The centers of the positive electrode annular group 8011 and the negative electrode annular group 8012 are the same but their radii are different. The positive electrode of the LED is connected to the component pad on the positive electrode annular group 8011, and the negative electrode of the LED is connected to the component pad on the negative electrode annular group 8012. In this way, one LED is connected between each positive and negative electrode, thus forming a circularly distributed LED array, so that when the LED array is lit, it can cover the entire pupil.

[0083] It should be noted that the embodiments of this application do not specifically limit the number of light-emitting diodes in the light-emitting diode array.

[0084] Therefore, the wireless full-field photostimulator provided in this application embodiment, through the design of a circular light-emitting diode array, allows sufficient stimulation light to enter the pupil, thereby improving the photostimulation effect.

[0085] Optionally, there may be multiple ring groups, with the same center and different radii for each ring group, and a preset distance between adjacent ring groups.

[0086] In this embodiment, the preset distance refers to the distance between two adjacent ring groups. By setting the preset distance, the radii of multiple ring groups can be progressively reduced according to the distance from the pupil in the retina. The light-emitting diode array provided on the ring group can completely cover the pupil.

[0087] Specifically, since sufficient stimulation light needs to enter the pupil during electroretinography (ERG) detection, and contact lens-type photostimulation devices do not require external obstruction, the LED array that circles the pupil in the above embodiment can be modified to cover the entire pupil to improve the photostimulation effect. Figure 9This is a schematic diagram of another ring assembly provided in an embodiment of this application, as shown below. Figure 9 As shown, there are multiple ring groups 801, namely, multiple positive rings 8011 and multiple negative rings 8012. With the pupil in the retina as the center, the farther the distance of each ring group 801 from the center, the larger its corresponding radius. That is, the centers of multiple ring groups are the same but the radii are different. In this way, the radii of the multiple deployed ring groups 801 can decrease step by step according to the distance from the pupil in the retina, so as to achieve full coverage of the pupil by the light-emitting diode array and enhance the light stimulation effect.

[0088] It is understandable that, because LEDs are transparent, the light emitted by the LED array can be directly input into the pupil without loss through intermediate media. Therefore, full coverage can achieve more efficient full-field light stimulation.

[0089] Therefore, the wireless full-field photostimulator of this application embodiment, by deploying multiple ring groups, allows as many light-emitting diode arrays as possible to cover and stimulate the pupil, thereby enhancing the effect of photostimulation.

[0090] It should be noted that the number of ring groups is not specifically limited in the embodiments of this application; there can be two or three groups, and the effect of photostimulation can still be achieved.

[0091] Optionally, the contact mirror-type photostimulation device further includes: an insulating layer, circuit traces, and through holes;

[0092] The light-emitting diode array, the energy receiving coil, and the ring group are disposed on one side of the insulating layer; the circuit traces and impedance matching module are disposed on the other side of the insulating layer.

[0093] The insulating layer has through holes;

[0094] The circuit traces are used to pass through the vias to connect the LED array, the energy receiving coil, the ring assembly, and the impedance matching module.

[0095] Specifically, the contact lens-type photostimulation device comprises two metal layers, respectively disposed on both sides of an insulating layer. The first metal layer, defined as the layer closest to the corneal surface, includes components such as an energy receiving coil, a light-emitting diode array, and a ring assembly. The second metal layer, defined as the layer furthest from the corneal surface, mainly includes other necessary structures for achieving a closed circuit, such as circuit traces, impedance matching modules, and components for rectification and voltage regulation. The circuit traces serve as wires between the various components and modules, and the two metal layers are connected through through-holes in the insulating layer.

[0096] For example, Figure 10This is a schematic diagram of the circuit traces and vias provided in the embodiments of this application, such as... Figure 10 As shown, the contact mirror photostimulation device also has multiple through holes 1001 and multiple circuit traces 1002. The circuit traces 1002 can pass through the through holes 1001 to connect the energy receiving coil, impedance matching module, light-emitting diode array and other components together.

[0097] It should be noted that the embodiments of this application do not specifically limit the components corresponding to some other necessary structures for implementing closed circuits. For example, components such as resistors may be included.

[0098] Therefore, the wireless full-field photostimulator provided in this application embodiment connects the circuits by having circuit traces pass through various through holes in the insulating layer, so that the wireless full-field photostimulator operates in a closed circuit.

[0099] It should be noted that if multiple ring groups are deployed in a contact lens photostimulation device, the connection method of the circuit traces passing through the through holes is similar to that described above, and will not be repeated here.

[0100] Optionally, the insulating layer and the outer surface of the contact lens photostimulator are both made of flexible polymers, and the outer surface of the contact lens photostimulator is used to directly contact the cornea.

[0101] In this embodiment, the insulating layer refers to the processing substrate and the flexible insulating layer 302 in the above embodiments, and the outer surface of the contact mirror photostimulation device refers to the flexible material 301 in the above embodiments.

[0102] Preferably, the materials used for the processing substrate and the flexible insulating layer 302 are generally flexible materials that are permitted to directly contact biological tissues in clinical medicine, such as parylene and polyimide. Since the outer surface of the contact lens-type photostimulation device needs to directly contact the cornea, materials such as silicone hydrogel and poly(hydroxyethyl methacrylate) (PHEMA) are typically chosen. This allows for the creation of a truly clinically wearable contact lens-type wireless full-field photostimulator, achieving a flexible wireless full-field photostimulator.

[0103] Therefore, by using flexible polymers for the outer surface and insulating layer of the contact lens photostimulator, users can directly wear a full-field photostimulator for electroretinography (ERG) testing, giving the ERG testing system the potential for flexibility, home use, and intelligence, which aligns with the modern medical development concept of precision medicine.

[0104] In conjunction with the above embodiments, this application also provides a wireless full-field-of-view light stimulation method, applied to a wireless full-field-of-view light stimulator, the wireless full-field-of-view light stimulator including a contact lens-type light stimulation device that contacts the cornea and covers the pupil, and an energy transmission frame eyeglass; the method includes:

[0105] The energy transmitting coil in the energy transmission frame glasses receives power from the power module and transmits electrical signals;

[0106] The energy receiving coil in the contact lens photostimulator receives the electrical signal and drives the light-emitting diode array in the contact lens photostimulator to emit light.

[0107] For example, in Figure 1 In the application scenario, when user 101 wants to test the retina for diseases at home, they can wear the wireless full-field photostimulator 102 and activate it. Furthermore, the energy transmitting coil in the energy transmission frame glasses of the wireless full-field photostimulator 102 receives power from the power module and transmits an electrical signal to the energy receiving coil in the contact lens photostimulator. Furthermore, the energy receiving coil receives the electrical signal and drives the light-emitting diode array in the contact lens photostimulator to emit light, thus completing the photostimulation.

[0108] The beneficial effects of the wireless full-field optical stimulation method provided in this application can be referred to the description of the above embodiments, and will not be repeated here.

[0109] Optionally, in response to manual activation of the wireless full-field light stimulator, the light-emitting diode array emits light stimulation to enable electrodes to collect electroretinogram (ERG) signals generated after the retina receives the light stimulation, and sends the ERG signals to an amplifier for processing.

[0110] In this embodiment, electrodes can be attached around the eye to collect electroretinogram (ERG) signals generated after the retina receives light stimulation. The ERG signal is generated by stimulating the retina with flashes of light of a certain intensity, and the potential changes can be recorded in the visual cortex or the occipital region outside the skull for the diagnosis of eye diseases. The amplifier can refer to a device that amplifies the input ERG signal, which consists of an electron tube or transistor, a power transformer and other electrical components, including a galvanometer that displays the current trend in the form of an image.

[0111] For example, in Figure 1In the application scenario, if user 101 activates the wireless full-field photostimulator 102, the wireless full-field photostimulator 102 can provide photostimulation to the retina. Furthermore, the eye generates potential changes, i.e., electroretinogram signals. Then, the potential changes are transmitted to an amplifier by electrodes placed at the corresponding positions on the skin. The results are displayed by the amplifier's ammeter or on an oscilloscope for user 101 to view.

[0112] It is understandable that a controller can be added to the wireless full-field photostimulator. After the amplifier amplifies the electroretinogram (ERG) signal, the amplified ERG signal can be sent to the doctor's terminal device for review, allowing for timely detection of any suspicious retinal lesions. This application does not specifically limit the content or form of transmission to the terminal device; it can send an image containing the amplified ERG signal via SMS, or send an analysis of the ERG signal's trend via email.

[0113] Therefore, the embodiments of this application can be manually activated to perform retinal detection using a wireless full-field photostimulator, without restricting patient activity and facilitating home-based detection.

[0114] This application also provides an electronic device. Figure 11 This is a schematic diagram of the structure of an electronic device provided in an embodiment of this application, such as... Figure 11 As shown, the electronic device includes: a wireless full-field light stimulator 1101, an electrode 1102, and an amplifier 1103;

[0115] The electrode 1102 is used to collect the electroretinogram signal generated after the retina receives light stimulation from the wireless full-field light stimulator 1101, and send the electroretinogram signal to the amplifier 1103.

[0116] The amplifier 1103 is used to receive the electroretinogram signal and display it on the corresponding ammeter.

[0117] It should be noted that the amplifier includes a galvanometer for displaying electroretinogram (ERG) signals. Optionally, the amplifier can also send the ERG signals to an oscilloscope for display. This application does not specifically limit this aspect.

[0118] This allows users to view the data directly, improving convenience. Furthermore, it can send electroretinogram (ERG) signals to doctors' terminal devices, enabling doctors to view and analyze whether any abnormalities have occurred in the retina.

[0119] The aforementioned terminal devices can be either wireless or wired. A wireless terminal can be a device that provides voice and / or other service data connectivity to a user, a handheld device with wireless connectivity, or other processing devices connected to a wireless modem. The wireless terminal can communicate with one or more core network devices via a Radio Access Network (RAN). The wireless terminal can be a mobile terminal, such as a mobile phone (or "cellular" phone) or a computer with a mobile terminal, for example, a portable, pocket-sized, handheld, computer-embedded, or vehicle-mounted mobile device, which exchanges voice and / or data with the RAN. Furthermore, a wireless terminal can also be a Personal Communication Service (PCS) phone, a cordless phone, a Session Initiation Protocol (SIP) phone, a Wireless Local Loop (WLL) station, a Personal Digital Assistant (PDA), or other similar devices. A wireless terminal can also be referred to as a system, subscriber unit, subscriber station, mobile station, mobile station, remote station, remote terminal, access terminal, user terminal, user agent, user device, or user equipment; no specific terminology is used here. Optionally, the aforementioned terminal devices can also be smartwatches, tablets, or other similar devices.

[0120] In the several embodiments provided in this application, it should be understood that the disclosed wireless full-field-of-view photostimulator and method can be implemented in other ways. For example, the wireless full-field-of-view photostimulator embodiments described above are merely illustrative. For instance, the division of modules is only a logical functional division, and in actual implementation, there may be other division methods. For example, multiple modules or components may be combined or integrated into another system, or some features may be ignored or not executed. Furthermore, the displayed or discussed mutual couplings, direct couplings, or communication connections may be through some interfaces. The indirect couplings or communication connections between the wireless full-field-of-view photostimulator or modules may be electrical, mechanical, or other forms.

[0121] The modules described as separate components may or may not be physically separate. The components shown as modules may or may not be physical units; that is, they may be located in one place or distributed across multiple network units. Some or all of the modules can be selected to implement the solution of this embodiment according to actual needs.

[0122] Furthermore, the functional modules in the various embodiments of this application can be integrated into one processing unit, or each module can exist physically separately, or two or more modules can be integrated into one unit. The aforementioned modular unit can be implemented in hardware or in the form of hardware plus software functional units; this application does not limit this approach.

[0123] The above description is merely a specific implementation of the embodiments of this application, but the protection scope of the embodiments of this application is not limited thereto. Any changes or substitutions within the technical scope disclosed in the embodiments of this application should be covered within the protection scope of the embodiments of this application. Therefore, the protection scope of the embodiments of this application should be determined by the protection scope of the claims.

Claims

1. A wireless full-field-of-view light stimulator, characterized in that, include: Contact lens-type photostimulation devices that contact the cornea and cover the pupil, and energy-transmitting eyeglasses; The energy transmission frame glasses are equipped with an energy transmitting coil for connection to the power module, which transmits electrical signals when powered by the power module. The contact lens photostimulation device is equipped with an energy receiving coil and a light-emitting diode array. The energy receiving coil is used to receive the electrical signal and drive the light-emitting diode array to emit light. The light-emitting diode array is configured to emit light directly into the pupil when driven, so as to achieve full-field photostimulation of the retina. The contact lens photostimulation device further includes: a ring group; the ring group includes a positive electrode ring and a negative electrode ring, the positive electrode ring and the negative electrode ring having the same center but different radii; The positive electrode ring is connected to one end of the energy receiving coil, and the negative electrode ring is connected to the other end of the energy receiving coil; The light-emitting diode array includes a plurality of light-emitting diodes disposed between the positive electrode ring and the negative electrode ring of the ring group, wherein one end of the light-emitting diode is connected to the positive electrode ring and the other end is connected to the negative electrode ring; There are multiple ring groups, and the centers of the multiple ring groups are the same but the radii are different. The distance between two adjacent ring groups is a preset distance.

2. The wireless full-field optical stimulator according to claim 1, characterized in that, The contact lens-type photostimulation device also includes: An impedance matching module is connected in parallel with the energy receiving coil to match the resonant frequencies of the energy transmitting coil and the energy receiving coil.

3. The wireless full-field optical stimulator according to claim 1, characterized in that, The power module includes a battery and a circuit board; the battery transmits a power supply signal to the circuit board, and the circuit board generates a sinusoidal voltage signal with a frequency greater than a preset threshold based on the signal; The power module is located in the temple of the energy transmission frame glasses, and the energy transmitting coil is located in the frame of the energy transmission frame glasses.

4. The wireless full-field optical stimulator according to claim 1, characterized in that, The energy transfer frame glasses also include: A focusing lens is used to reflect and focus the light scattered outward by the light-emitting diode array into the pupil.

5. The wireless full-field optical stimulator according to claim 2, characterized in that, The contact mirror-type photostimulation device also includes: an insulating layer, circuit traces, and through holes; The light-emitting diode array, the energy receiving coil, and the ring group are disposed on one side of the insulating layer; the circuit traces and the impedance matching module are disposed on the other side of the insulating layer. The insulating layer has through holes; The circuit traces are used to pass through the vias to connect the LED array, the energy receiving coil, the ring assembly, and the impedance matching module.

6. The wireless full-field optical stimulator according to claim 5, characterized in that, The insulating layer and the outer surface of the contact lens photostimulator are both made of flexible polymers, and the outer surface of the contact lens photostimulator is used to directly contact the cornea.

7. A wireless full-field optical stimulation method, characterized in that, The method is applied to the wireless full-field photostimulator according to any one of claims 1-6, the wireless full-field photostimulator comprising a contact lens-type photostimulation device that contacts the cornea and covers the pupil, and an energy-transmitting eyeglass frame; the method comprises: The energy transmitting coil in the energy transmission frame glasses receives power from the power module and transmits electrical signals; The energy receiving coil in the contact lens photostimulator receives the electrical signal and drives the light-emitting diode array in the contact lens photostimulator to emit light.

8. An electronic device, characterized in that, include: The wireless full-field optical stimulator, electrode, and amplifier as described in any one of claims 1-6; The electrode is used to collect the electroretinogram (ERG) signal generated after the retina receives light stimulation from the wireless full-field light stimulator, and to send the ERG signal to the amplifier. The amplifier is used to receive the electroretinogram signal and display it on the corresponding ammeter.

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