A combination of lncRNAs and its model for diagnosing gliomas

By detecting the expression levels of six lncRNAs in human peripheral blood, a multi-molecular biomarker model was constructed, which solved the problem of inaccurate prognostic evaluation of glioma in existing technologies and achieved higher predictive accuracy and patient risk grouping capabilities.

CN115198021BActive Publication Date: 2026-05-26ZHONGNAN HOSPITAL OF WUHAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHONGNAN HOSPITAL OF WUHAN UNIV
Filing Date
2022-08-23
Publication Date
2026-05-26

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Abstract

This invention discloses an oligonucleotide probe combination for detecting the expression levels of six lncRNAs in human peripheral blood. The six lncRNAs are C1RL-AS1, LINC00968, MIR155HG, CPB2-AS1, LINC00906, and WDR11-AS1. Detecting the expression levels of these six key lncRNAs in human peripheral blood using this probe combination can predict the prognosis of glioma patients. This invention provides a new method for the clinical diagnosis of gliomas and has significant clinical value and promising prospects for widespread application.
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