A medical consumable covering mechanism, nucleic acid testing equipment, and covering method.

Abstract

This invention discloses a closing mechanism for medical consumables, a nucleic acid testing device, and a closing method. The closing mechanism includes a capping part, a clamping unit, a driving unit, and a relative motion driving unit. The testing device includes the aforementioned medical consumable closing mechanism. The closing method includes a capping part directly or indirectly connected to the cap of the consumable being closed. The capping part includes a clamping unit that applies a clamping force to the cap. The clamping unit is controlled to connect with the cap in a partial area to apply a clamping force to the cap. The capping part is controlled to generate relative motion with the consumable being closed, and during this relative motion, the entire cap is clamped and connected to the consumable being closed. The advantage of this invention is that the closing operation can be reliably closed by sufficient and uniform clamping force.

Description

Technical Field

[0001] This invention relates to the technical field of medical devices, specifically to a sealing mechanism for medical consumables, a nucleic acid testing device, and a sealing method. Background Technology

[0002] Automated analytical equipment plays an increasingly important role in various types of sample analysis. Automated equipment can effectively solve problems such as labor shortages, high requirements for the professionalism of operators, and monotonous operations caused by long-term repetitive work. In particular, in recent years, with people's pursuit of a high-quality life and the challenging situation brought about by changes in the ecological environment, more and more testing needs need to be met. For example, in health screening during childbirth, in the optimization and development of animal husbandry to make plants more suitable for raising animals, in public epidemic prevention and control screening and prevention in sudden diseases, in the verification of evidence in criminal investigation and similar investigations, and in customs inspections and other scenarios. Therefore, developing more automated equipment is an urgent matter. Typically, from samples (such as secretions, saliva, sweat, and excretions), collected swabs (including throat swabs, nasal swabs, anal swabs, blood, etc.), to the final analyte, there are many processing steps involved. Often, the reagents and reaction solutions required for these processing steps vary depending on the environment. Therefore, the optimal choice is to perform different reactions in different consumable wells and use automated sample transfer devices (such as pipettes ADP) to transfer the sample solution to different wells. The reaction consumables designed in this way are usually a collection type of consumables, containing multiple sample reaction wells with different functions.

[0003] In certain scenarios (such as nucleic acid extraction or other related nucleic acid reactions), operations involving sample transfer, lysis, washing, and elution are required. A design that integrates multiple consumable structures, including pipette tip storage wells, stirring sleeve storage wells, and wells for lysis, washing, and elution, creates a multi-well consumable. In practice, this type of consumable requires opening and closing the cap to complete the necessary transfer and lysis operations. Closing the cap ensures timely and effective sealing of the consumable after each operation, preventing contamination risks. Furthermore, the cap is closed after the consumable is removed from the automated equipment, minimizing the risk of infection to the experimenter. However, existing automated equipment rarely incorporates this type of multi-functional integrated device. US patent application US20160250640A1 designs a device with combined functional consumables and processing capabilities. It utilizes a specific handheld holder to simultaneously feed multiple combined functional consumables. To prevent contamination during use, a puncture-resistant sealing film is used to seal the consumables. However, currently, most tip consumables are made of plastic, and the risk of breakage due to puncturing the sealing film is very high, making the design unreliable. Chinese patent CN107727874B clearly shows the consumable structure used in the aforementioned device by Beckton Dickinson. It is designed with a puncture-resistant sealing film covering the extraction port, while other parts lack corresponding covers, thus the risk of contamination exists even when the cover is open. US patent US11130137B2 also uses a similar flexible sealing film for contamination prevention. Zhengzhou Antu also borrowed from Becton Dickinson's design, using puncture-resistant membrane structures to seal some of the openings, as disclosed in Chinese Utility Model Patent CN216427262U. However, this easily puncturable material cannot be completely sealed like rubber materials. Once testing is complete, the entire consumable may still be at risk of leakage, which is unacceptable for large-scale testing with potential positive results. This could lead to contamination of laboratory personnel and inaccurate data. US Patent Application US20120129156A1 discloses an integrated consumable using a matching hard-shell type cap. This type of cap has advantages such as reliable sealing and low leakage risk. The cap in this invention is also made of an impermeable material. Chinese Patent CN111847343B discloses a method for opening and closing the consumable cap; however, its design is mainly for opening. In actual use, the insufficient pressure applied to the cap during closing can lead to unreliable closure, and gaps between the cap and the consumable body can pose a risk of aerosol contamination.

[0004] In order to solve the technical problem of unreliable closure of the cover due to insufficient clamping force during the closing process, it is urgent to develop a new type of closing mechanism and method to ensure that sufficient and basically uniform clamping force can be applied to different parts during the closing process. Summary of the Invention

[0005] The purpose of this invention is to provide a medical consumable closing mechanism, a nucleic acid testing device, and a closing method, which solves the problem of unreliable closure of the cap caused by insufficient clamping force during the closing process of existing consumables.

[0006] The objective of this invention is achieved through the following technical solution:

[0007] A medical consumable closing mechanism includes: a pressure cap portion directly or indirectly connected to a consumable cover to be closed; a clamping unit contained within the pressure cap portion, which applies a clamping force to the consumable cover; a driving unit that drives the pressure cap portion to different states, thereby connecting or separating the clamping unit from the consumable cover to be closed; when the clamping unit is driven to connect with the consumable cover, the clamping unit and the consumable cover are in a partially connected state, thereby applying a clamping force to a portion of the consumable cover; and a relative motion driving unit that causes relative motion between the consumable cover and the pressure cap portion, thereby pressing the entire consumable cover onto the consumable body to be closed during the relative motion.

[0008] Furthermore, it also includes a support unit, in which the consumable body is housed, and a relative motion drive unit is included within the support unit.

[0009] Furthermore, the clamping unit is a rotating roller structure.

[0010] Furthermore, when the consumable cover is connected to the clamping unit to apply clamping force to a portion of the consumable cover, the connection type is a line contact.

[0011] Furthermore, it also includes a limiting mechanism, which includes an elastic unit to ensure that the consumable cover is elastically locked by the elastic unit during the closing process to prevent misalignment.

[0012] Furthermore, the clamping unit consists of N clamping units connected in parallel, where N is an integer greater than two, enabling simultaneous closing of no more than N consumable covers.

[0013] Furthermore, the clamping unit consists of eight clamping units connected in parallel, enabling simultaneous closing of no more than eight consumable covers.

[0014] Furthermore, it also includes a cover opening and closing module, which includes an upper working layer and a lower working layer. The upper working layer is set as a stationary layer for connecting the instrument, and a position adjustment motor is connected to the lower working layer to drive the lower working layer to move up and down to perform the opening or closing operation.

[0015] Furthermore, the drive unit includes a drive motor, which drives a drive gear on the output shaft to rotate. The drive gear meshes with a sector-shaped output gear on the pressure cover. The sector-shaped output gear drives the hinged pressure cover to swing up or down, thereby connecting or separating the pressing unit from the consumable cover.

[0016] Furthermore, the drive unit includes a drive motor, which drives the pulley to rotate via a conveyor belt, thereby transmitting the rotational motion of the motor to a rotating shaft. The rotating shaft drives the first bevel gear to rotate, and the first bevel gear transmits the rotational motion to the second bevel gear through meshing. The second bevel gear drives the transmission rod to rotate and swing via a transmission shaft. The long groove at the end of the transmission rod is fitted with the swing shaft of the pressure cap, causing the hinged pressure cap to swing up or down, thereby connecting or separating the pressing unit from the consumable cover.

[0017] A nucleic acid testing device for medical consumables includes a medical consumable sealing mechanism to close the consumables, thereby fulfilling the operational requirement of sealing the consumables during the testing process.

[0018] A method for closing a medical consumable includes a pressing part that is directly or indirectly connected to the consumable cover to be closed. The pressing part includes a pressing unit that applies a pressing force to the consumable cover. The pressing unit is controlled to be connected to the consumable cover in a partial area to apply a pressing force to the consumable cover. The pressing part is controlled to generate relative movement between the pressing part and the consumable to be closed. During the relative movement, the entire consumable cover is pressed and connected to the consumable body to be closed.

[0019] Furthermore, it also includes a drive unit that controls the separation or connection of the consumable cover being closed with the clamping unit.

[0020] The beneficial effects of this invention are:

[0021] 1. This invention employs a drive unit to drive the pressure cap, causing the pressure unit to contact a portion of the consumable cover being closed. This ensures that the pressure force converted from the drive power output by the drive motor acts only on a portion of the cover. This generates a sufficiently large pressure force within the affected area, allowing the consumable cover and the consumable body to be tightly fastened together first. Then, through the relative motion drive unit, the consumable being closed and the pressure cap move relative to each other. During this relative movement, the entire consumable cover is pressed and connected to the consumable body being closed, thus ensuring that the entire closing operation is reliably closed by a sufficient and uniform pressure force.

[0022] 2. The relative motion drive unit is located on the support unit that houses the consumable body, thus achieving a separation design of the drive and clamping functions, ensuring the reliability of the closing mechanism. The clamping unit is designed as a roller structure, which can ensure that the resistance during the relative motion process is small. By controlling the contact area, the output power of the drive motor in the drive unit can be converted into a larger clamping force, thereby realizing a reliable connection between the consumable cover and the consumable body in a certain area. The limiting mechanism of the consumable cover can ensure that the cover is locked after opening and that no relative misalignment occurs, thus ensuring that the design of the entire closing mechanism is simplified to the maximum extent.

[0023] 3. By setting up N parallel pressing units, the closing mechanism can reliably close multiple consumables at the same time, ensuring the system's high efficiency. The optimal configuration of eight units per group allows a maximum of eight consumables to be closed simultaneously, meeting the needs of larger processing volumes.

[0024] The aforementioned main solution of the present invention and its various further alternative solutions can be freely combined to form multiple solutions, all of which are solutions that can be adopted and are claimed by the present invention; furthermore, the (non-conflicting alternatives) can also be freely combined with each other and with other alternatives. Those skilled in the art, after understanding the solution of the present invention, will realize from the prior art and common general knowledge that there are many combinations, all of which are technical solutions to be protected by the present invention, and will not be exhaustively listed here. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the traditional consumable sealing principle.

[0026] Figure 2 This is a schematic diagram illustrating the closing principle of the consumables in this invention.

[0027] Figure 3 This is a schematic diagram of the closing action of the consumable in this invention.

[0028] Figure 4 This is a schematic diagram of the structure of the first driving unit of the present invention.

[0029] Figure 5 This is a schematic diagram of the structure of the first type of drive unit of the present invention.

[0030] Figure 6 This is a schematic diagram of the structure of the second type of driving unit of the present invention.

[0031] Figure 7 This is a schematic diagram of the second type of moving unit installation according to the present invention.

[0032] Figure 8 This is a schematic diagram of the different states and actions of the cover switch module of the present invention.

[0033] Figure 9 This is a schematic diagram of the pressing unit of the present invention.

[0034] Figure 10 This is a schematic diagram of the structure of the elastic unit of the present invention.

[0035] Figure 11 This is a schematic diagram illustrating the action of closing the lid at the beginning of the present invention.

[0036] Figure 12 This is a schematic diagram of the actions performed during the closing operation of the present invention.

[0037] Figure 13 This is a schematic diagram illustrating the action of closing the lid in this invention.

[0038] In the diagram: 20-Drive unit, 30-Cover part, 301-Clamping unit, 302-Roller frame, 40-Bearing part, 100-Switch cover module, 110-Position adjustment motor, K101-Elastic unit; 201-Drive motor, 202-Drive gear, 203-Sector output gear, 204-Rotating shaft, 205-First bevel gear, 206-Second bevel gear, 207-Transmission rod, 208-Conveyor belt; 101-Consumable cover, 102-Consumable body; P10-Clamping force, S101-Surface type clamping part, S102-Line type clamping part, F101-Surface type clamping force, F102-Line type clamping force, S1021-Clamping contact part, RM01-Relative motion. Detailed Implementation

[0039] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0040] Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely to illustrate selected embodiments of the application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.

[0041] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0042] Example 1:

[0043] As revealed in the background section, in automated nucleic acid extraction systems designed to facilitate amplification, multifunctional consumables are becoming the preferred solution for an increasing number of manufacturers. By prefabricating components such as the tip, stirring sleeve, lysis buffer, washing buffer, and elution buffer at different well locations to create a multifunctional consumable, the system's full automation can be maximized. Automated operation also reduces human intervention and minimizes the risk of infection to laboratory personnel. This invention employs a non-puncture-resistant sealing method between the consumable cap and the consumable body. Therefore, corresponding opening and closing mechanisms are needed to prevent contamination during system operation. Chinese prior art patent CN111847343B discloses a sample tube opening and closing mechanism; however, in practical use, the clamping force converted from the power output of the pressing motor alone has a high probability of sealing failure for this type of multifunctional consumable. Therefore, a reliable closing mechanism is needed to ensure reliable closing of such consumables.

[0044] Figure 1 and Figure 2 This invention analyzes the forces acting on the same consumables during closing for two different types of closing mechanisms. To ensure system processing capacity, this invention allows for parallel testing of samples from eight different objects at a time. Figure 1 and Figure 2 In the comparison, the load-bearing parts are all under full load. Figure 1 The structure illustrates a traditional pressure application scheme, where the clamping force P10 is converted from the maximum output power of the motor. The clamping force application part in this traditional scheme can be simplified to a surface-type clamping part S101 with a certain effective area. Under the action of the position adjustment part, it can connect or contact the integrated consumable cover 101, thereby allowing the clamping force P10 to act on the integrated consumable cover 101 for closing. The consumable body 102, which is being closed, is placed on the support part 40. Under the action of the clamping force P10, the integrated consumable cover 101 can be fastened onto the consumable body 102. Because the area of ​​force application is large throughout the clamping process, the magnitude of the average surface-type clamping force F101 acting on the local area can be illustrated as follows: Figure 1As a result, the force at this point is actually relatively small. However, generally, this type of consumable, being used in the extraction process, has certain requirements regarding sample volume and reaction volume, etc. Furthermore, the sample requires a certain level of sealing reliability. Therefore, the fastening is generally achieved by using materials with a certain interference fit or the elastic or plastic deformation of materials capable of a certain degree of deformation. Some also use the interlocking of protrusions and recesses. These sealing methods actually require a relatively large clamping force to overcome the resistance during the connection process between the cap and the body. However, the existing clamping methods do not translate into a large local clamping force. Therefore, in actual experiments, it was found that most consumables did not completely and reliably close the cap. Once truly used in automated instruments… Figure 1 This approach could potentially lead to the risk of contamination from leaked used sample solutions, which is neither permissible nor acceptable in medical devices involving biological experiments.

[0045] To overcome the above problems, this application proposes a medical consumable closing mechanism, comprising: a pressure cap portion 30, which is directly or indirectly connected to the consumable cover 101 to be closed; a clamping unit 301, which is included in the pressure cap portion 30 and applies a clamping force to the consumable cover 101; a driving unit 20, which drives the pressure cap portion 30 to different states to connect or separate the clamping unit 301 from the consumable cover 101 to be closed; when the clamping unit 301 is driven to connect with the consumable cover 101, the clamping unit 301 and the consumable cover 101 are in a partially connected state, thereby applying a clamping force to a portion of the consumable cover 101; and a relative motion driving unit, which causes the consumable cover 101 and the pressure cap portion 30 to move relative to each other, thereby pressing the entire consumable cover 101 onto the consumable body 102 to be closed.

[0046] It also includes a support portion 40, within which the consumable body 102 is housed, and a relative motion drive portion is also included within the support portion 40. The clamping unit 301 is a rotating roller structure. The consumable cover 101 is partially connected to the clamping unit 301, so that when a clamping force is applied to a portion of the consumable cover 101, the connection type is a line contact.

[0047] The clamping unit 301 consists of N clamping units connected in parallel, where N is an integer greater than two, enabling the simultaneous closing of no more than N consumable cover 101s. Alternatively, the clamping unit 301 can consist of eight clamping units connected in parallel, enabling the simultaneous closing of no more than eight consumable cover 101s.

[0048] Figure 2This is a schematic diagram of the closing mechanism of the present invention and its force analysis during the closing process. Since the clamping motor remains unchanged, the clamping force P10 converted from the maximum power output of the motor remains unchanged. At this time, the closing mechanism can be simplified according to the force to the structure of the linear clamping part S102. Under the action of the position adjustment part, the linear clamping part S102 can be directly or indirectly connected to the consumable cover 101 to be closed through the clamping unit 301, so as to apply a clamping force to the consumable cover 101. At this time, it can be seen from the figure that it is partially connected to the consumable cover 101, so as to apply a clamping force to a part of the consumable cover 101. Figure 2 It is evident that the linear clamping force F102 applied to the local cover is much greater than the surface clamping force F101 applied to the same location. Therefore, this design can provide sufficient closing clamping force to overcome the resistance during the closing process, thereby enabling the local cover to be reliably closed.

[0049] Figure 3 This diagram illustrates the entire process of reliably closing the cover using a large clamping force from localized contact, combined with relative motion. With the assistance of the position adjustment unit, the clamping contact part S1021 partially contacts the consumable cover 101; preferably, the contact is a line contact rather than a line contact. Figure 1 The surface contact type allows for the application of relatively large clamping force to a specific area, ensuring a reliable connection between the integrated consumable cover 101 and the consumable body 102. The integrated consumable cover 101 can be made of plastic with a certain degree of hardness (or elasticity), ensuring that applying clamping force only locally prevents breakage. The clamping contact part S1021 can be configured as a roller structure. In this case, the clamping contact part S1021 applies clamping force to a portion of the consumable cover 101. When the consumable cover is connected to the clamping contact part S1021, and clamping force is applied to a portion of the consumable cover 101, the connection type is a line contact, thus generating a sufficiently large clamping force. Under the action of relative motion RM01, the roller can roll from a localized area of ​​the integrated consumable cover 101 to all positions of the consumable cover 101. Figure 3 The illustration demonstrates how a roller structure, in conjunction with relative motion RM01, enables a reliable connection between the consumable cover and the consumable body. The roller structure ensures that during the closing process, the pressing contact S1021 and the integrated consumable cover 101 experience rolling friction due to relative motion. This reduces the risk of wear and deformation of the pressing contact S1021, while also ensuring the reliability of the closing process. It minimizes the risk of closing failure due to dislocations caused by sliding friction. Of course, non-roller solutions can be used in special scenarios; this is not a limitation here.

[0050] Example 2:

[0051] Figure 4 This illustration shows an implementation scheme of a drive unit 20, which can drive the pressure cap 30 to different states, realizing different states of connection or separation between the pressing unit 301 and the consumable cover 101 being closed. In this embodiment, the drive mechanism includes a drive motor 201, which outputs driving force for switching between different states. The drive motor 201 drives the drive gear 202 connected to the drive motor 201 to rotate via an output shaft. The drive gear 202 is meshed with a sector output gear 203, and the two achieve effortless output through a configured module ratio. The sector output gear 203 is fixed on the pressure cap 30 to enable the drive unit 20 to output a reliable locking force to the pressure cap 30. The middle part of the pressure cap 30 is hinged to achieve swing rotation. The sector output gear 203 drives the hinged pressure cap 30 to swing up or down, realizing the connection or separation of the pressing unit 301 and the consumable cover 101. Of course, in the separated state, the motor only needs to be reversed to release the locking state. In order to achieve the previous solution of closing the cover by rolling and pressing, this embodiment adopts the design of the pressing unit 301 as a roller structure. In order to ensure that the equipment meets the requirements of efficient operation, the pressing unit 301 here is set as a parallel eight roller structure. The roller structure is installed on the roller frame 302 inside the cover part, and each adjacent roller can have an approximately similar spacing.

[0052] Figure 5 This is a switch cover module 100 formed in conjunction with the drive unit 20 of this embodiment. The position adjustment motor 110 can be the motor of the position adjustment part, and its output power can also be converted into a clamping force. Of course, in some cases, it can be used in conjunction with... Figure 4 The clamping force can be generated by the output of the drive motor 201 together with the clamping force, or it can be generated by the output power of the drive motor 201 alone. It is not limited here. With the help of the position adjustment part, the drive motor 201 can switch states, thereby causing the drive gear 202 to rotate, so that the cover part 30 is pressed down and locked. This allows the clamping unit 301 to be directly or indirectly connected to the consumable cover 101. The local application of clamping force enables the cover and the body to achieve a reliable connection at a local position under the action of greater clamping force. The opening principle and process will not be described in detail here.

[0053] The other structures are the same as in Example 1.

[0054] Example 3:

[0055] Figure 6Another implementation scheme of the drive unit 20 is illustrated. Unlike the structure of embodiment 2, this mechanism introduces an intermediate gear meshing transmission to achieve reversal. That is, the rotating shaft 204 drives the first bevel gear 205 of the meshing gear pair to rotate, and then transmits the rotational motion to the second bevel gear 206. The second bevel gear 206 drives the transmission rod 207 to rotate and swing through the transmission shaft. The long groove at the end of the transmission rod 207 is fitted with the swing shaft of the pressure cover part 30. The transmission rod 207 applies a driving force to the pressure cover part 30 to change its state. The middle part of the pressure cover part 30 is hinged to achieve swing rotation. The upper part of the pressure cover part 30 is pushed by the transmission rod, causing the hinged pressure cover part 30 to swing up or down, so as to connect or separate the pressing unit 301 from the consumable cover 101.

[0056] In this embodiment and Embodiment 2, the connecting mechanism of the transmission rod 207 and the connecting structure of the drive gear 202 meshing with the sector output gear 203 can both achieve the function of locking. Other similar locking structure designs are also acceptable.

[0057] Figure 7 This is a switch cover module 100 formed in conjunction with the drive unit 20 of this embodiment. The position of the drive motor 201 that changes the state is different from that in embodiment 2. This design can ensure that the motor has a large installation space. Here, it can be designed that the drive motor 201 drives the pulley to rotate through the conveyor belt 208, thereby transmitting the rotational motion of the motor to the rotating shaft 204. When it is necessary to release the locked contact state, it is only necessary to reverse the motor to achieve an effect similar to that in embodiment 2.

[0058] The other structures are the same as in Example 1.

[0059] Example 4:

[0060] Figure 8 The diagram illustrates a cover switch module 100 operating in different states. The module has different working layers. The upper working layer is a stationary layer connected to the instrument. A position adjustment motor 110 is connected to the lower working layer, causing it to move up and down, simultaneously driving the drive unit 20 and the pressure cap 30 to perform the opening or closing position adjustment operation. To ensure position accuracy, a connecting rod and a limiting unit located on the connecting rod are provided between the different working layers. Figure 8 The raised position on the left indicates whether the lid is open or in a completed state. Figure 8 The descending position on the right indicates whether the lid is being opened or closed.

[0061] Figure 9The diagram illustrates the action of the clamping unit 301 on the cover after the upper working layer is removed. The position adjustment motor 110 of the position adjustment part drives the downward pressure. When the consumable cover 101 and the consumable body 102 are about to be connected, the drive motor 201 presses down to make the clamping unit 301, driven by the cover part 30, first contact the integrated consumable cover 101 part to lock it, and then apply a large pressure to the integrated consumable cover 101 part with the converted clamping force to complete the closing of the consumable.

[0062] Figure 10 This is a schematic diagram of a switch cover assembly mechanism with an elastic unit K101. It includes a limiting mechanism for the consumable cover, which contains the elastic unit K101. This limiting mechanism ensures that the consumable cover is elastically locked during the closing process, preventing dislocation. After the integrated consumable cover is opened, the consumable cover 101 directly presses against the elastic unit K101, thus locking it in place. By ensuring that the switch cover is in the same position, the correct connection between the cover and the main body is guaranteed, ensuring a simple and low-cost structural implementation. The elastic unit K101 and the clamping unit 301 are located at different positions with a predetermined distance between them. The elastic unit K101 is optimally located at the center or near the center, while the clamping unit 301 is located at the edge. The relative motion drive is included in the consumable carrier, so that the clamping unit 301 of the present invention does not need to be driven to move, thus ensuring the simplicity of the opening and closing mechanism. Since the carrier 40 itself needs to be in different positions to perform operations such as pipetting, extraction, and amplification, the same motor is used to simultaneously drive the relative motion, which simplifies the design of moving parts and ensures the reliability of the system.

[0063] The other structures are the same as in Example 1.

[0064] Example 5:

[0065] A nucleic acid testing device for medical consumables includes a capping mechanism as described in Examples 1, 2, 3, or 4 to close the cap, thus fulfilling the requirement of sealing the consumables during the testing process. This capping mechanism can be used to close integrated extraction consumables, while for PCR reaction consumables, due to their small volume, traditional capping methods can be used directly to close the cap; this is not a limitation.

[0066] Example 6:

[0067] A method for closing a medical consumable includes a pressing part 30 that is directly or indirectly connected to the consumable cover 101 to be closed. The pressing part 30 includes a pressing unit 301 that applies a pressing force to the consumable cover 101. The pressing unit 301 is controlled to be connected to the consumable cover 101 in a partial area to apply a pressing force to the consumable cover 101. The pressing part 30 is controlled to generate relative movement with the consumable to be closed. During the relative movement, the consumable cover 101 is pressed and connected to the consumable body 102 to be closed.

[0068] It also includes a drive unit 20 that controls the separation or connection of the consumable cover 101 to the clamping unit 301 during the closing process. This method can be implemented using the closing mechanism of Embodiments 1, 2, 3 or 4 to ensure that the clamping force is sufficient to guarantee the reliability of the closing process.

[0069] Figures 11-13 This diagram illustrates the method for closing the lid using the lid-opening / closing mechanism of the present invention within the lid-opening / closing module. Before the experiment begins, the user places the integrated consumable in its closed state into the consumable slot of the support unit 40. The position adjustment motor 110 drives the lower working layer of the lid-opening / closing module 100 to descend along the Z-axis, completing the lid-opening operation of the integrated consumable. Afterward, the support unit 40 is driven to different positions to perform operations such as pipetting and extraction, and then moves back to the open position to perform the lid-closing operation. Similarly, the position adjustment motor 110 drives the lower working layer to descend along the Z-axis. Because the lower working layer contains an elastic locking structure, the integrated consumable cover 101 can be lowered without offset to a state where it is about to connect with the consumable body 102 located on the support part 40. At this time, the drive motor 201, in conjunction with the change in state, drives the cover and body to be pressed together and locked. The resulting clamping force achieves a relatively large clamping force engagement between the two parts. Through the relative motion drive motor driving the movement of the support part 40, the pressing unit 301 achieves rolling motion on the upper surface of the cover. Figure 12 As shown, a larger clamping force can be gradually and evenly applied to a larger contact surface. Further driving, as... Figure 13 As shown, uniform clamping force can be applied to almost all surfaces of the cover, thereby ensuring reliable sealing between the consumable cover and the consumable body. Then, the position adjustment motor 110 drives the module to rise to the initial position to complete the closing operation.

[0070] It should be noted that the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0071] In the description of this invention, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

Claims

1. A medical consumables covering mechanism, characterized in that, include: The switch cover module (100) includes a drive unit (20) and a pressure cover part (30). The pressure cap (30) is directly or indirectly connected to the consumable cover (101) that is being closed; A clamping unit (301) is included in the pressure cover (30). The clamping unit (301) applies a clamping force to the consumable cover (101). The clamping unit (301) is a rotating roller structure. The drive unit (20) drives the pressure cover part (30) to swing up or down, so as to connect or separate the pressure unit (301) from the consumable cover (101) to be closed. When the pressure unit (301) is driven to connect with the consumable cover (101), the pressure unit (301) and the consumable cover (101) are in a partially connected state, so as to apply a pressure force to a part of the consumable cover (101). The partial connection type is line contact. The carrier (40) and the consumable body (102) are housed within the carrier (40), and the relative motion drive unit is included within the carrier (40); The relative motion drive unit causes the consumable cover (101) and the pressure cover (30) to move relative to each other. In the relative motion between the two, the consumable cover (101) is pressed and connected to the consumable body (102) that is closed. The switch cover module (100) includes an upper working layer and a lower working layer. The upper working layer is set as a stationary layer for connecting the instrument. The position adjustment motor (110) is connected to the lower working layer and drives the lower working layer to move up and down, synchronously driving the drive unit (20) and the cover part (30) to move. The lower working layer contains an elastic locking structure. The integrated consumable cover (101) is lowered without offset to a state that is about to be connected to the consumable body (102) located in the support part (40), thereby performing the opening or closing operation.

2. The medical consumables covering mechanism according to claim 1, characterized in that: It also includes a limiting mechanism, which includes an elastic unit (K101) to ensure that the consumable cover (101) is elastically clamped by the elastic unit (K101) during the closing process and does not cause dislocation.

3. The medical consumables covering mechanism according to claim 1, characterized in that: The drive unit (20) includes a drive motor (201), which drives the drive gear (202) on the output shaft to rotate. The drive gear (202) meshes with the sector output gear (203) on the pressure cover (30). The sector output gear (203) drives the hinged pressure cover (30) to swing up or down, thereby connecting or separating the pressing unit (301) from the consumable cover (101).

4. The medical consumables covering mechanism according to claim 1, characterized in that: The drive unit (20) includes a drive motor (201). The drive motor (201) drives the pulley to rotate via the conveyor belt (208), thereby transmitting the rotational motion of the drive motor (201) to the rotating shaft (204). The rotating shaft (204) drives the first bevel gear (205) to rotate. The first bevel gear (205) transmits the rotational motion to the second bevel gear (206) through meshing. The second bevel gear (206) drives the transmission rod (207) to rotate and swing via the transmission shaft. The long groove at the end of the transmission rod (207) is fitted with the swing shaft of the pressure cap (30), causing the hinged pressure cap (30) to swing up or down, thereby connecting or separating the pressing unit (301) from the consumable cover (101).

5. A nucleic acid testing device for medical consumables, characterized in that, Includes the medical consumable sealing mechanism as described in any one of claims 1 to 4, to fulfill the operational requirement of sealing consumables during the testing process.

6. A method for closing medical-related consumables, characterized in that: The medical consumable closing mechanism according to any one of claims 1 to 4 includes a pressure cap part (30) directly or indirectly connected to the consumable cover (101) to be closed. The pressure cap part (30) includes a pressure unit (301) that applies pressure to the consumable cover (101). The pressure unit (301) is controlled to be connected to the consumable cover (101) in a partial area to apply pressure to the consumable cover (101). The pressure cap part (30) is controlled to generate relative movement with the consumable to be closed. In the relative movement, the consumable cover (101) is pressed and connected to the consumable body (102) to be closed.

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