结构化照明的相位掩模

By using a phase mask instead of an SLM, the problems of high cost and low efficiency of SLM devices are solved, achieving efficient and low-cost illumination beam modulation, improving microscope imaging resolution, and is particularly suitable for Raman spectroscopy and fluorescence spectroscopy.

CN115297765BActive Publication Date: 2026-07-17THERMO SCI INSTR CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THERMO SCI INSTR CO LTD
Filing Date
2021-02-16
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In existing structured illumination microscope systems, spatial light modulators (SLMs) are expensive, inefficient, and require complex optical and electronic overhead, making it difficult to efficiently modulate the intensity and phase of the illumination beam.

Method used

A phase mask, comprising a light-blocking layer disposed on a substrate, with multiple optical transmission zones and segments of different phase configurations, is used to generate stripe patterns, replacing the SLM device.

Benefits of technology

It enables efficient and low-cost modulation of the intensity and phase of the illumination beam, improving imaging resolution, especially imaging quality in Raman spectroscopy and fluorescence spectroscopy.

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Abstract

描述相位掩模的实施例,所述相位掩模包括安置于衬底上的挡光层,其中所述挡光层具有多个光学透射区,每一光学透射区被配置为第一图案。所述第一图案包含具有彼此不同的相位配置的两个片段,并且所述挡光层包含所述第一图案的至少三个角定向。
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