一种抗肽基脯氨酰基顺反异构酶D-IgG抗体的检测试剂盒
By developing an anti-peptidyl prolyl cis-trans isomerase D-IgG antibody detection kit, we have filled the gap in antibody detection for autoimmune nephrotic syndrome, achieved non-invasive etiological detection, simplified the operation, reduced the risk of cross-infection, and provided a basis for early diagnosis.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZHEJIANG UNIV
- Filing Date
- 2021-07-01
- Publication Date
- 2026-07-17
AI Technical Summary
The lack of existing technologies for detecting antibodies against peptidyl-prolyl cis-trans isomerase D-IgG makes it difficult to determine the etiology of autoimmune nephrotic syndrome, affecting early diagnosis and treatment.
A detection kit for anti-peptidyl-prolyl cis-trans isomerase D-IgG antibody was developed. The antibody in serum was detected by immune reaction with the peptidyl-prolyl cis-trans isomerase D antigen protein. Qualitative and quantitative analysis was performed using a solid-phase carrier and labeled antibody.
It enables non-invasive detection of autoimmune nephrotic syndrome, clarifies the etiology, reduces patient suffering and economic burden, provides a simple method for large-scale screening, and reduces the probability of cross-infection.
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Figure CN115616211B_ABST