Microfluidic chip, methods of operating the same and uses thereof
By integrating a reaction cell, a flow channel, and a waste liquid pool into a microfluidic chip structure, the complex problems of sample addition and waste liquid discharge in existing technologies are solved, achieving low-cost, pollution-proof, and sensitive biological detection, supporting digital ELISA and digital PCR detection.
CN115624991BActive Publication Date: 2026-06-12IOMICS BIOSCIENCES INC +1
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- IOMICS BIOSCIENCES INC
- Filing Date
- 2022-09-27
- Publication Date
- 2026-06-12
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Figure CN115624991B_ABST
Abstract
The present application relates to biological detection, in particular to a microfluidic chip and its operation method and use. The microfluidic chip comprises a lower shell, the lower shell comprising a reaction cell, a flow guide groove and a waste liquid pool formed on the inner surface of the lower shell and communicating with each other; a chip body arranged in the chip area of the reaction cell; an upper shell comprising a sample inlet hole penetrating through the upper shell and corresponding to the sample inlet end of the reaction cell, a gas permeation hole penetrating through the upper shell and corresponding to the waste liquid pool, and a gas discharge groove formed on the outer surface of the upper shell and communicating with the gas permeation hole. The microfluidic chip of the present application has the functions of preventing pollution, reliable detection, sensitivity, rapidness, simple structure and low price.
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