A basic experimental rat fixing device
By using an arc-shaped baffle, an arc-shaped airbag, and a translational mechanism driven by a servo motor, the problems of unstable fixation and insufficient operational adaptability of existing devices for rats with smaller body diameters are solved, achieving stability for different rats and convenience for various operations, thus improving experimental efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- WEST CHINA HOSPITAL SICHUAN UNIV
- Filing Date
- 2022-11-01
- Publication Date
- 2026-07-21
AI Technical Summary
Existing rat restraint devices cannot effectively restrain rats with small body diameters and cannot meet the needs of different experimental operations, especially blood collection and dissection operations other than tail vein manipulation.
A basic experimental rat fixation device was designed, which uses an arc-shaped baffle hinged to a baffle plate and connected by a spring. Combined with an arc-shaped airbag and a translational mechanism driven by a servo motor, it can fix rats of different body diameters and lengths. It is equipped with a tail fixation tube and a detachable abdominal fixation plate to adapt to various experimental operations.
It enhances the fixation effect on rats, improves experimental efficiency, and adapts to different experimental operation requirements, especially the convenience of tail vein puncture and other site operations.
Smart Images

Figure CN115721439B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of basic experimental technology, and more specifically, to a basic experimental rat restraint device. Background Technology
[0002] Rats, as commonly used laboratory animals, occupy an extremely important position in basic medical research. Basic rat experiments involve procedures such as drug injection, blood collection, anesthesia, and dissection. These procedures involve manipulating various parts of the rat's body; all of these procedures require the rat to be restrained beforehand.
[0003] Chinese invention patent (CN106037982B) discloses an adjustable rat restraint device. This device features a length-adjustable baffle, the top of which can slide back and forth, allowing for the restraint of rats of different sizes. However, this device only considers the length of the rat, neglecting its body diameter. Consequently, smaller rats can still roll over within the device, making effective restraint impossible. Furthermore, the design concept of this device, which places the rat within a restraint sleeve, only allows for tail vein manipulation; other procedures such as blood collection and dissection are not possible. This makes it difficult to perform these basic experimental procedures on rats.
[0004] Based on the above problems, the applicant invented a basic experimental rat restraint device. Summary of the Invention
[0005] The purpose of this invention is to provide a basic experimental rat fixation device that can fix rats of different lengths and body sizes, thereby enhancing the fixation effect and improving the experimental efficiency of researchers.
[0006] The above-mentioned technical objective of the present invention is achieved through the following technical solution: a basic experimental rat fixation device, comprising a base plate, a baffle plate on the top of the base plate, and a head fixation mechanism on the side wall of the baffle plate; the top of the base plate is also provided with a sliding groove with an open top, and a translation mechanism is provided in the sliding groove; the top of the translation mechanism is provided with multiple flat plates and a tail fixation cylinder, and the top of each of the multiple flat plates is provided with an abdominal fixation cylinder;
[0007] The head fixing mechanism includes multiple arc-shaped baffles, multiple connecting blocks, and multiple springs; one end of each arc-shaped baffle is hinged to the side wall of the baffle; the multiple arc-shaped baffles are arranged in a ring; the multiple connecting blocks are slidably mounted on the side wall of the multiple arc-shaped baffles near the baffle; the ends of the multiple springs are connected to the multiple connecting blocks; and the ends of the multiple springs away from the connecting blocks are fixedly connected to the side wall of the baffle.
[0008] The abdominal fixation tube includes two arc-shaped fixation plates; the two arc-shaped fixation plates are hinged together, the connection between the two arc-shaped fixation plates is connected to the top of the flat plate, and the ends of the two arc-shaped fixation plates away from the flat plate are detachably connected.
[0009] Both of the two arc-shaped fixing plates have arc-shaped airbags on their opposite sidewalls. Both of the arc-shaped fixing plates have an inflatable branch pipe embedded in them. One end of the inflatable branch pipe is connected to the arc-shaped airbag, and the other end of the inflatable branch pipe is provided with a diverter. The diverter end of the diverter is connected to both inflatable branch pipes at the same time, and the air inlet end of the diverter is provided with an inflatable main pipe.
[0010] The end of the tail fixing cylinder away from the arc-shaped fixing plate is provided with a cover.
[0011] By employing the above technical solution, multiple arc-shaped baffles are distributed along the same arc, hinged to the baffle plate, and connected by springs. This allows for the fixation of rats with different head sizes, enhancing the fixation effect. An arc-shaped air bladder is installed inside the tail fixation cylinder, connected to an inflation branch tube. Inflating the arc-shaped air bladder allows for the fixation of rats with different body diameters. A translational mechanism is connected to both the tail fixation cylinder and the flat plate, allowing adjustment of the distance between the arc-shaped baffles and the translational mechanism to fix rats of different lengths. The abdominal fixation cylinder uses a combination of two arc-shaped fixation plates, one end of which is detachable. This allows experimenters to selectively open the arc-shaped fixation plates according to the specific operating location, effectively fixing the rats while facilitating operation. This device fixes rats using both length and body diameter dimensions, enhancing the fixation effect.
[0012] The present invention is further configured such that: the translation mechanism includes a servo motor, a threaded rod, a bearing, and a plurality of sliders; the servo motor and the bearing are respectively fixedly connected to both ends of the slide groove, the end of the threaded rod is fixedly connected to the output end of the servo motor, and the end of the threaded rod away from the servo motor is fixedly connected to the inner ring of the bearing; the plurality of sliders are simultaneously sleeved on the threaded rod, and the tops of the plurality of sliders are respectively fixedly connected to a flat plate or a tail fixing cylinder.
[0013] By adopting the above technical solution, the slider is sleeved on the threaded rod, and the slider is connected to the tail fixing cylinder and multiple plates respectively. In this way, the rotation of the servo motor causes the tail fixing cylinder and the arc-shaped fixing plate to move left and right, thereby achieving the effect of fixing rats of different lengths.
[0014] The present invention is further configured such that: a plurality of vent holes are provided on the side wall of the arc-shaped baffle; a plurality of vent holes are also provided between the connection points of the plurality of arc-shaped baffles and the baffle plate.
[0015] By adopting the above technical solution, multiple ventilation holes are opened in the arc-shaped baffle and baffle plate, so as to prevent the rat from suffocating when it is fixed.
[0016] The invention is further configured such that: the outer wall of the cover is threadedly connected to the inner wall of the tail fixing cylinder, the side wall of the cover is provided with a through tail hole; and the outer wall of the cover is provided with a handle.
[0017] By adopting the above technical solution, a tail hole is opened on the side wall of the cover, through which the rat's tail can be placed outside the device. This makes it easier for the experimenter to perform tail vein puncture on the rat and improves the applicability of the fixation device. A handle is fixedly installed on the side wall of the cover, which makes it easier for the experimenter to install or remove the cover.
[0018] The invention is further configured such that the connection between the two arc-shaped fixing plates is made of screws, and the top of the screws is provided with a handle.
[0019] By adopting the above technical solution, a second handle is fixedly installed on the top of the screw, which facilitates the disassembly or connection of the arc-shaped fixing plate by the experimenter.
[0020] In summary, the present invention has the following beneficial effects:
[0021] 1. Multiple arc-shaped baffles are distributed along the same arc, and the arc-shaped baffles are hinged to the baffle. At the same time, springs connect the arc-shaped baffles to the baffle. This can fix rats with different head sizes and enhance the fixation effect.
[0022] 2. An arc-shaped air bladder is provided inside the tail fixing tube, and the arc-shaped air bladder is connected to the inflation branch tube. In this way, rats of different body sizes can be fixed by inflating the arc-shaped air bladder.
[0023] 3. Connect the translation mechanism to both the tail fixing cylinder and the plate. This allows for adjustment of the distance between the arc-shaped baffle and the translation mechanism, thereby enabling the fixation of rats of different lengths.
[0024] 4. The abdominal fixation tube uses a combination of two arc-shaped fixation plates, and one end of each arc-shaped fixation plate is detachable. This allows the experimenter to selectively open the arc-shaped fixation plates according to the specific operation site. This not only effectively fixes the rat but also facilitates the experimenter's operation.
[0025] 5. This device fixes the rat by measuring both length and body diameter, thereby enhancing the rat's immobilization effect. Attached Figure Description
[0026] Figure 1This is a side sectional view of a basic experimental rat restraint device in an embodiment of the present invention;
[0027] Figure 2 yes Figure 1 Cross-sectional view at point AA;
[0028] Figure 3 This is a cross-sectional view of the vertical plane where the screw is located in an embodiment of the present invention;
[0029] Figure 4 This is a cross-sectional view of the vertical plane where the inflation branch pipe is located in an embodiment of the present invention.
[0030] In the diagram: 1. Baffle; 2. Arc-shaped baffle; 3. Vent hole; 4. Base plate; 5. Servo motor; 6. Threaded rod; 7. Slider; 8. Flat plate; 9. Slide groove; 10. Arc-shaped fixing plate; 11. Bearing; 12. Tail hole; 13. Handle one; 14. Cover; 15. Tail fixing cylinder; 16. Arc-shaped airbag; 17. Handle two; 18. Diverter head; 19. Inflation branch pipe; 20. Screw; 21. Inflation main pipe; 22. Connecting block; 23. Spring. Detailed Implementation
[0031] The following is in conjunction with the appendix Figure 1-4 The present invention will be described in further detail below.
[0032] Example: A basic experimental rat restraint device, such as Figures 1 to 4 As shown, it includes a base plate 4, a baffle 1 is fixedly installed on the top of the base plate 4, and a head fixing mechanism is fixedly installed on the side wall of the baffle 1; the top of the base plate 4 also has a sliding groove 9 with an open top, and a translation mechanism is fixedly installed in the sliding groove 9; the top of the translation mechanism is fixedly connected to 4 flat plates 8 and 1 tail fixing cylinder 15, and the top of each of the 4 flat plates 8 is fixedly installed with an abdominal fixing cylinder.
[0033] In this preferred embodiment, the head fixing mechanism includes four arc-shaped baffles 2, four connecting blocks 22, and four springs 23; one end of each of the four arc-shaped baffles 2 is hinged to the side wall of the baffle 1; as shown Figure 2 As shown, four arc-shaped baffles 2 are arranged in a ring; four connecting blocks 22 are slidably installed on the side walls of the four arc-shaped baffles 2 near the baffle 1. In this embodiment, the sliding connection is achieved by opening a groove 9 on the arc-shaped baffle 2, with a part of the connecting block 22 located in the groove 9, and the bottom being wider and the middle being narrower, thus achieving the limiting function; the ends of four springs 23 are respectively connected to the four connecting blocks 22. When not in use, the springs 23 are in the normal state, and the ends of the four springs 23 away from the connecting blocks 22 are fixedly connected to the side walls of the baffle 1.
[0034] The four abdominal fixation tubes include two arc-shaped fixation plates 10; the two arc-shaped fixation plates 10 are hinged together, and the connection between the two arc-shaped fixation plates 10 is connected to the top of the plate 8. The ends of the two arc-shaped fixation plates 10 away from the plate 8 are as follows: Figure 3 and Figure 4 The two arc-shaped fixing plates 10 are connected by a screw 20. Both arc-shaped fixing plates 10 have the same size threaded grooves and can be aligned. The screw 20 is then inserted into the two identical threaded grooves by rotation, thereby fixing the two arc-shaped fixing plates 10.
[0035] Arc-shaped airbags 16 are attached to the opposite sidewalls of the two arc-shaped fixing plates 10. Inflation branch pipes 19 are embedded in the two arc-shaped fixing plates 10. One end of the inflation branch pipe 19 is connected to the arc-shaped airbag 16, and the other end of the inflation branch pipe 19 is connected to a diverter head 18. The diverter end of the diverter head 18 is connected to both inflation branch pipes 19 at the same time. The air inlet end of the diverter head 18 is connected to an inflation main pipe 21. The inflation main pipe 21 can be connected to a pump body, so that the two arc-shaped airbags 16 can be inflated at the same time.
[0036] A cover 14 is installed at the end of the tail fixing cylinder 15 away from the arc-shaped fixing plate 10. In this embodiment, as shown... Figure 1 As shown, the outer wall of the cover 14 is threadedly connected to the inner wall of the tail fixing cylinder 15. The side wall of the cover 14 has a through tail hole 12, which allows the rat's tail to pass through, making it convenient for the experimenter to perform tail vein puncture. The outer wall of the cover 14 is also fixedly equipped with a handle 13, which is convenient for the experimenter to disassemble or install.
[0037] The translation mechanism includes a servo motor 5, a threaded rod 6, a bearing 11, and five sliders 7. The servo motor 5 and the bearing 11 are fixedly connected to the two ends of the slide groove 9, the end of the threaded rod 6 is fixedly connected to the output end of the servo motor 5, and the end of the threaded rod 6 away from the servo motor 5 is fixedly connected to the inner ring of the bearing 11. The five sliders 7 are simultaneously sleeved on the threaded rod 6, the tops of four sliders 7 are fixedly connected to four flat plates 8, and the other is fixedly connected to the tail fixing cylinder 15.
[0038] like Figure 2 As shown, multiple ventilation holes 3 are opened on the side wall of the arc-shaped baffle 2; multiple ventilation holes 3 are also opened between the multiple arc-shaped baffles 2 and the baffle 1.
[0039] The two arc-shaped fixing plates 10 are connected by a screw 20, and a handle 2 17 is fixedly connected to the top of the screw 20.
[0040] Working principle: When using this device, the experimenter first removes the cover 14, then places the rat into the arc-shaped fixing plate 10 and the tail fixing cylinder 15, and then reinstalls the cover 14. The servo motor 5 is rotated by adjusting the button (not marked in the figure). The rotation of the servo motor 5 drives the threaded rod 6 to rotate. Since the sliders 7 are all fixedly sleeved on the threaded rod 6, the tail fixing cylinder 15 and the arc-shaped fixing plate 10 move the rat together towards the arc-shaped baffle 2. After the rat's head is pressed against the arc-shaped baffle 2, air is injected into the inflation tube 21. The gas enters the arc-shaped air bladders 16 on both sides through the diverter 18. After the arc-shaped air bladders 16 inflate, their surfaces will adhere tightly to the rat's body, thus fixing the rat. When it is necessary to inject fluid into a specific part of the rat's abdomen, simply open the arc-shaped fixing plate 10 at the corresponding part by rotating the screw 20 to remove it. This device can pass the rat's tail through the tail hole 12, which makes it easier for the experimenter to perform tail vein injection after fixing the rat.
[0041] This specific embodiment is merely an explanation of the present invention and is not intended to limit the invention. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they are within the scope of the claims of the present invention.
Claims
1. A basic experimental rat restraint device, comprising a base plate (4), characterized in that: The bottom plate (4) is provided with a baffle (1) at the top, and a head fixing mechanism is provided on the side wall of the baffle (1); the bottom plate (4) is also provided with a sliding groove (9) with an open top, and a translation mechanism is provided in the sliding groove (9); the top of the translation mechanism is provided with multiple flat plates (8) and a tail fixing cylinder (15), and the top of each of the multiple flat plates (8) is provided with an abdominal fixing cylinder; The head fixing mechanism includes multiple arc-shaped baffles (2), multiple connecting blocks (22), and multiple springs (23); one end of each of the multiple arc-shaped baffles (2) is hinged to the side wall of the baffle (1); the multiple arc-shaped baffles (2) are arranged in a ring; the multiple connecting blocks (22) are slidably installed on the side wall of the multiple arc-shaped baffles (2) near the baffle (1); the ends of the multiple springs (23) are connected to the multiple connecting blocks (22); and the ends of the multiple springs (23) away from the connecting blocks (22) are fixedly connected to the side wall of the baffle (1). The abdominal fixation tube includes two arc-shaped fixation plates (10); the two arc-shaped fixation plates (10) are hinged together, the connection between the two arc-shaped fixation plates (10) is connected to the top of the plate (8), and the ends of the two arc-shaped fixation plates (10) away from the plate (8) are detachably connected. Arc-shaped airbags (16) are provided on the opposite sidewalls of the two arc-shaped fixing plates (10). Inflation branch pipes (19) are embedded in the two arc-shaped fixing plates (10). One end of the inflation branch pipe (19) is connected to the arc-shaped airbag (16). The other end of the inflation branch pipe (19) is provided with a diverter head (18). The diverter head (18) is connected to both inflation branch pipes (19) at the same time. The inlet end of the diverter head (18) is provided with an inflation main pipe (21). The end of the tail fixing cylinder (15) away from the arc-shaped fixing plate (10) is provided with a cover (14); the outer side wall of the cover (14) is threadedly connected to the inner side wall of the tail fixing cylinder (15), and the side wall of the cover (14) is provided with a through tail hole (12); the outer side wall of the cover (14) is provided with a handle (13). The translation mechanism includes a servo motor (5), a threaded rod (6), a bearing (11), and multiple sliders (7); the servo motor (5) and the bearing (11) are respectively fixedly connected to the two ends of the slide groove (9), the end of the threaded rod (6) is fixedly connected to the output end of the servo motor (5), and the end of the threaded rod (6) away from the servo motor (5) is fixedly connected to the inner ring of the bearing (11); multiple sliders (7) are simultaneously sleeved on the threaded rod (6), and the tops of the multiple sliders (7) are respectively fixedly connected to the plate (8) or the tail fixing cylinder (15).
2. The basic experimental rat restraint device according to claim 1, characterized in that: The side wall of the arc-shaped baffle (2) is provided with multiple ventilation holes (3); multiple ventilation holes (3) are also provided between the multiple arc-shaped baffles (2) and the baffle (1).
3. The basic experimental rat restraint device according to claim 1, characterized in that: The two arc-shaped fixing plates (10) are connected by a screw (20), and the top of the screw (20) is provided with a handle (17).