An electric field generating device

Abstract

The application relates to an electric field generating device, comprising a processing module, a signal generating module and at least one electric field acting component connected in sequence, wherein the processing module is used for acquiring characteristic data of a target object and generating waveform parameters for stimulating the target object according to the characteristic data; the signal generating module is used for generating an electric field signal matched with the waveform parameters; and the at least one electric field acting component is used for receiving the electric field signal to form a spatial electric field acting on the target object. When the electric field generating device provided by the application acts on the target object, a spatial electric field with different electric field parameters, such as different frequencies and different electric field strengths, can be generated according to the characteristic data of the target object, so as to meet the requirements of various electric field strengths or various working frequencies and the like when stimulating the target object, and the inhibitory effect can meet the requirements of individualized treatment.

Description

Technical Field

[0001] This application relates to the field of medical technology, and in particular to an electric field generating device. Background Technology

[0002] Tumor-Treating Fields (TTF) therapy is a novel cell therapy modality. It delivers low-intensity, medium-frequency, alternating electric fields to the lesion area, interfering with the division process of cancer cells and causing tumor cell death, thus achieving a therapeutic effect. The basic principle of tumor-treating field therapy is based on the inhibitory and destructive effect of electric fields on tumor cell mitosis. Typically, an electric field generated by a 200kHz electrical signal is used to inhibit the rapid growth of the patient's tumor cells, thereby achieving a therapeutic effect.

[0003] In related technologies, a single-frequency electric field signal is often used to act on tumor cells. However, the ability of a single frequency to act has certain limitations and cannot produce a high degree of inhibition on all types of tumor cells. Summary of the Invention

[0004] Based on this, and in response to the aforementioned technical problems, this application provides an electric field generating device that can address the limitations of using electric field signals with a single waveform parameter to suppress tumor cells in related technologies.

[0005] In a first aspect, embodiments of this application provide an electric field generating device, comprising a processing module, a signal generating module, and at least one electric field acting component connected in sequence, wherein...

[0006] The processing module is used to acquire feature data of the target object and generate waveform parameters for stimulating the target object based on the feature data;

[0007] The signal generation module is used to generate an electric field signal that matches the waveform parameters;

[0008] The at least one electric field-acting component is used to receive the electric field signal to form a spatial electric field acting on the target object.

[0009] The electric field generating device provided in this application embodiment can be used to inhibit the mitosis of target objects such as tumor cells. Specifically, it can generate waveform parameters that match the characteristic data of the target object. Different target objects have different characteristic data. Correspondingly, the waveform parameters of the electric field signal are different, and the generated spatial electric field is also different. In this way, when the electric field generating device is used to act on the target object, it can generate spatial electric fields with different electric field parameters, such as different frequencies and different electric field intensities, according to the characteristic data of the target object. This adapts to the needs of stimulating the target object with multiple electric field intensities or multiple operating frequencies, so that the inhibitory effect meets the needs of personalized treatment.

[0010] Optionally, in one embodiment of this application, the electric field generating device is coupled to a terminal for receiving feature data of the target object.

[0011] Optionally, in one embodiment of this application, the terminal is further configured to receive reference waveform parameters input by the user; correspondingly, the processing module is further configured to generate waveform parameters for stimulating the target object based on the feature data and the reference waveform parameters.

[0012] Optionally, in one embodiment of this application, the number of signal generation modules is multiple, and the multiple signal generation modules are used to generate electric field signals with different waveform parameters; correspondingly, the processing module is used to select a target signal generation module at the time of frequency switching, and the target signal generation module generates an electric field signal of the frequency to be switched before the time of switching.

[0013] Optionally, in one embodiment of this application, the signal generation module includes multiple registers for storing waveform parameters of different electric field signals; the signal generation module is also used to receive a waveform switching instruction sent by the processing module, and select a target register from the multiple registers according to the waveform switching instruction, wherein the target register stores waveform parameters of the electric field signal with the frequency to be switched.

[0014] Optionally, in one embodiment of this application, the feature data of the target object includes the cell size distribution ratio of the target object; correspondingly, the processing module is specifically used to determine the duration of action of the sensitive frequency or sensitive frequency range corresponding to the target cell size within a unit period based on the distribution ratio of the target cell size, so that the duration of action is positively correlated with the distribution ratio of the target cell size, so as to generate waveform parameters for stimulating the target object.

[0015] Optionally, in one embodiment of this application, the processing module is further configured to obtain a reference frequency and a reference frequency range; correspondingly, the processing module is configured to generate the waveform parameters for stimulating the target object based on the reference frequency, the frequency variation range, and the feature data.

[0016] Optionally, in one embodiment of this application, the electric field generating device further includes a visual parameter configuration interface, which is used to provide the user with the permission to input reference waveform parameters and / or characteristic data of the target object.

[0017] Optionally, in one embodiment of this application, the electric field generating device further includes a temperature sensor connected to the electric field acting component. The temperature sensor is connected to the processing module and is used to send the collected temperature information of the electric field acting component to the processing module. Correspondingly, when the processing module determines that the temperature information is greater than a preset temperature threshold, it stops outputting the waveform parameters used to stimulate the target object. Correspondingly, the signal generating module stops outputting the electric field signal used to stimulate the target object.

[0018] Optionally, in one embodiment of this application, the electric field action component includes at least one set of electrode patches, each set of electrode patches being attached to the surface of the target object in different directions to receive the electric field signal and form a spatial electric field that can penetrate the target object. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of this application, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of the modular structure of an electric field generating device according to one embodiment;

[0021] Figure 2 This is a schematic diagram illustrating the connection between an electric field generating device and a terminal according to an embodiment;

[0022] Figure 3 This is a schematic diagram illustrating an application scenario based on one embodiment;

[0023] Figure 4 This is a schematic diagram of the module structure of the filter module and the transformer module according to one embodiment;

[0024] Figure 5This is a schematic diagram of a visual parameter configuration interface according to one embodiment. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of this application clearer, the application is described and illustrated below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the application. All other embodiments obtained by those skilled in the art based on the embodiments provided in this application without inventive effort are within the scope of protection of this application. Furthermore, it is understood that although the efforts made in such a development process may be complex and lengthy, for those skilled in the art related to the content disclosed in this application, modifications to design, manufacturing, or production based on the technical content disclosed in this application are merely conventional technical means and should not be construed as insufficient disclosure of the content of this application.

[0026] In this application, the reference to "embodiment" means that a specific feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment that is mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described in this application may be combined with other embodiments without conflict.

[0027] Unless otherwise defined, the technical or scientific terms used in this application shall have the ordinary meaning understood by one of ordinary skill in the art to which this application pertains. The terms "a," "an," "a kind," "the," and similar words used in this application do not indicate quantity limitation and may indicate singular or plural. The terms "comprising," "including," "having," and any variations thereof used in this application are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or device that includes a series of steps or modules (units) is not limited to the listed steps or units, but may also include steps or units not listed, or may include other steps or units inherent to these processes, methods, products, or devices. The terms "connected," "linked," "coupled," and similar words used in this application are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "A plurality" used in this application means two or more. The terms "first," "second," "third," etc., used in this application are merely to distinguish similar objects and do not represent a specific ordering of objects.

[0028] Furthermore, to better illustrate this application, numerous specific details are provided in the following detailed description. Those skilled in the art should understand that this application can be implemented without certain specific details. In some instances, apparatus, means, elements, and circuits well known to those skilled in the art have not been described in detail in order to highlight the main points of this application.

[0029] The technical environment of this application's technical solution is described below. Currently, taking tumor cells as an example, a tumor-inhibiting electric field can periodically act on tumor cells, preventing the formation of spindle microtubules and the separation of intracellular organelles during cell division, inducing apoptosis during mitosis, thereby effectively disrupting tumor cell mitosis and inhibiting tumor cell proliferation to achieve therapeutic goals. Tumor cells can include malignant tissues of uncontrolled-growing degenerated cells, such as lymphoma, myeloma, chordoma, angiosarcoma, lymphangiosarcoma, etc. In actual cell experiments, it has been found that using an electric field generated by an electrical signal with the same waveform parameters to inhibit the rapid growth of tumor cells in different locations or of different sizes yields varying inhibitory effects. Clearly, the appropriate waveform parameters of the electric field signal differ for different tumor cells. For example, using a single-frequency electric field to inhibit different tumor cells may result in insufficient inhibitory effects for treatment. In other words, different tumor cells require different waveform parameters for the electric field signal.

[0030] Based on the above-mentioned technical environment, the electric field generating device provided in this application can adjust the waveform parameters of the electric field signal according to the characteristic data of tumor cells during the treatment of different cells, so as to generate different inhibitory electric fields, so that the inhibitory electric fields can inhibit different tumor cells and achieve the inhibitory effect to meet the treatment requirements.

[0031] Please see Figure 1 , Figure 1 A schematic diagram of an electric field generating device 100 according to an embodiment of this application is shown. Exemplarily, the electric field generating device 100 may include a processing module 101, a signal generating module 103, and at least one electric field acting component 105 connected in sequence, wherein...

[0032] The processing module 101 is used to acquire feature data of the target object and generate waveform parameters for stimulating the target object based on the feature data;

[0033] The signal generation module 103 is used to generate an electric field signal that matches the waveform parameters;

[0034] The at least one electric field action component 105 is used to receive the electric field signal to form a spatial electric field acting on the target object.

[0035] In this embodiment, the target object can be a tissue or organ of a human or animal. More specifically, the target object can be tumor cells, such as lung tumor cells, stomach tumor cells, lymphoma cells, etc. The characteristic data of the target object can be its size, the tissue or organ it belongs to, its quantity, etc. The processing module 101 can be an electronic device with data processing and data transmission / reception capabilities. For example, the processing module 101 can be a module capable of controlling the waveform parameters of an electric field signal. Specifically, the processing module 101 can include, but is not limited to, Field Programmable Gate Array (FPGA), Application Specific Integrated Circuit (ASIC), Central Processing Unit (CPU), Complex Programmable Logic Device (CPLD), Microcontroller Unit (MCU), Digital Signal Processor (DSP), or other programmable logic devices, transistor logic devices, etc. This application does not limit the type of processing module 101. In one embodiment of this application, the processing module 101 can acquire specific feature data of the target object, such as directly acquiring information about the tissue to which the tumor cells belong (lung), the cell size (16 μm), and the number (1000). In other embodiments of this application, the processing module 101 can also first acquire a medical image of the target object and then analyze and process the medical image to determine the feature data of the target object. The medical image can be a medical image obtained using imaging equipment such as CT scanning equipment, PET scanning equipment, MR scanning equipment, or pathological slides for the target object. For example, a medical image recognition model can be pre-established in the processing module 101, and the medical image recognition model is trained using multiple medical image samples. The medical image recognition model may include a model trained using machine learning methods. The machine learning methods mentioned may include deep learning methods, reinforcement learning methods, etc., and the generated models may include convolutional neural network models (CNN), recurrent neural network models (RNN), LeNet, ResNet, long short-term memory network models (LSTM), bidirectional long short-term memory network models (Bi-LSTM), etc., and this application does not impose any restrictions.The medical image recognition model can process medical images of target objects and output corresponding feature data.

[0036] In one embodiment of this application, the processing module 101 can directly acquire feature data of the target object, or it can indirectly acquire feature data of the target object. For example, it can receive feature data input by the user through a terminal coupled to the electric field generating device 100. Specifically, as... Figure 2 As shown, the electric field generating device 100 is coupled to the terminal 201 and is used to receive feature data of the target object.

[0037] In this embodiment, the terminal 201 is signal-coupled with the electric field generating device 100 and is used to receive waveform parameters of the target object input by the user. The terminal 201 can be wired or wirelessly connected to the electric field generating device 100; wireless connection can include Bluetooth, Wi-Fi, etc. The terminal 201 can be a smartphone, tablet, laptop, desktop computer, PDA, mobile internet device (MID), wearable device (e.g., smartwatch, smart bracelet), smart computer, smart vehicle device, etc. This application does not limit the type of terminal 201. The user can directly input specific feature data parameters and values ​​on the terminal 201, or only input medical images of the target object, which are then analyzed and processed by the processing module 101 to determine the final feature data. By inputting the feature data of the target object to the electric field generating device 100 through the terminal 201, the user can interact with the electric field generating device 100, meeting the user's personalized treatment needs.

[0038] In this embodiment, after acquiring the feature data of the target object, waveform parameters for stimulating the target object can be generated based on the feature data. Different target objects require different stimulation electric field parameters, and correspondingly, the waveform parameters of the electric field signal that generates the stimulation electric field are also different. The waveform parameters may include amplitude, frequency, peak value, effective value, duty cycle, etc. In one embodiment of this application, the processing module 101 may pre-set the correspondence between the feature data and the waveform parameters so that the corresponding waveform parameters can be determined based on the correspondence after the feature data is determined. The correspondence can take various forms, such as a correspondence table, a correspondence function, a correspondence model, etc. In one example, the correspondence table between the feature data and the waveform parameters is shown in Table 1 below.

[0039] Table 1. Correspondence between feature data and waveform parameters

[0040] Lungs, 19μm 200kHz, 20V Stomach, 25μm 160kHz, 50V

[0041] In one embodiment of this application, to improve the efficiency and accuracy of determining waveform parameters, the final waveform parameters can be determined by adjusting the reference waveform parameters input by the user. Specifically, the terminal 201 is further configured to receive the reference waveform parameters input by the user; correspondingly, the processing module 101 is further configured to generate waveform parameters for stimulating the target object based on the feature data and the reference waveform parameters.

[0042] In this embodiment, the user can input reference waveform parameters through the terminal 201. These reference waveform parameters can be preset by the user based on actual treatment needs and application scenarios. It is understood that the reference waveform parameters are user-set waveform parameters. To further determine more accurate waveform parameters, the reference waveform parameters can be adjusted based on the characteristic data of the target object. For example, when the target object is large, the frequency of the electric field signal can be reduced to obtain a better therapeutic effect. In one embodiment of this application, the user can also input waveform type, duration of action, and switching time through the terminal 201. The waveform type can include linear, stepwise, exponential, etc. After receiving the waveform type, duration of action, and switching time, the processing module 101 can determine the waveform parameters used to stimulate the target object in conjunction with the characteristic data. For example, in one example, such as... Figure 3 As shown, the user selects a stepped waveform with a duration of 0-t3 and switching times of t1, t2 (t2 = 2 × t1), and t3 (t2 = 3 × t1). Given that the maximum frequency of the waveform is fH and the minimum frequency is fL based on the target object's characteristic data, such as cell size, the frequency change information of the waveform within the duration of 0-t1 is f = fL + {(fc - fL) / t1} × t; within the duration of t1-t2, the frequency of the waveform is fixed and can be a reference frequency fc, i.e., f = fc. The reference frequency can be determined based on the characteristic data, such as cell type.

[0043] In this embodiment, the signal generation module 103 may include devices capable of generating electrical signals of various frequencies, waveforms, and output levels. For example, it may be a device capable of generating sine waves, square waves, triangle waves, sawtooth waves, and positive and negative pulse wave signals of different frequencies. Specifically, it may include, but is not limited to, pulse signal generators, function generators, radio frequency generators, microwave signal generators, etc. Preferably, in one embodiment of this application, the signal generation module 103 may include a Direct Digital Synthesizer (DDS). A DDS can generate various types of waveforms such as sine waves, triangle waves, square waves, and sawtooth waves. It not only has advantages such as low cost, low power consumption, and high resolution, but also the advantage of rapid switching. Therefore, it can achieve rapid switching between multiple waveform types or different waveform frequencies, meeting the high efficiency requirements in the tumor cell inhibition process. The signal generation module 103 can receive waveform parameters sent by the processing module 101 and can generate an electric field signal matching the waveform parameters. The at least one electric field acting component 105 is coupled to the signal generating module 103, and can receive the electric field signal and form a spatial electric field acting on the target object. The coupling method can include a wired connection or a wireless connection. It is understood that the electric field acting component 105 can be directly connected to or coupled to the signal generating module 103, or it can be indirectly connected to the signal generating module 103 through an intermediate element, such as a filter, amplifier, etc. In one embodiment of this application, as... Figure 4 As shown, the signal generation module 103 can be connected to the filtering module 107. The filtering module 107 can perform low-pass filtering on the generated electric field signal, for example, by setting a suitable cutoff frequency to filter out the harmonic components of the high-frequency signal in the electric field signal. The waveform type and frequency of the electric field signal do not change before and after filtering. The filtering module 107 is connected to the transformer module 109, which is used to boost the filtered electric field signal to generate the target electric field signal. Moreover, since the transformer module 109 only has a magnetic path and no electrical path, it has an electrical isolation function, which can isolate the high current at the input end from the output end, so that the output target electric field signal is a low-current signal, preventing the high current signal from harming the human body and improving the personal safety of the user. It should be noted that, in one embodiment of this application, the electric field generating device 100 may also include a clock module 1011, which is connected to the signal generation module 103 and is used to provide a clock signal to the signal generation module 103.

[0044] In this embodiment, the electric field acting component 105 may include a probe, an electrode patch, etc. When the electric field acting component 105 is a probe, it can be inserted into a target object. The probe may include multiple electrodes capable of contacting biological tissues or organs. When the electric field acting component 105 is an electrode patch, the electrode patches are arranged in pairs and attached to the surface of the target object, for example, they may be attached to the skin of the target object. It is understood that when the electric field acting component 105 is an electrode patch, a spatial electric field penetrating the target object can be formed, thereby effectively inhibiting cell mitosis and improving the therapeutic effect.

[0045] The electric field generating device 100 provided in this embodiment can be used to inhibit the mitosis of target objects such as tumor cells. Specifically, it can generate waveform parameters that match the characteristic data of the target object. Different target objects have different characteristic data. Correspondingly, the waveform parameters of the electric field signal are different, and the generated spatial electric field is also different. In this way, when the electric field generating device 100 is used to act on the target object, it can generate spatial electric fields with different electric field parameters, such as different frequencies and different electric field intensities, according to the characteristic data of the target object. This adapts to the needs of stimulating the target object with multiple electric field intensities or multiple operating frequencies, so that the inhibition effect meets the needs of personalized treatment.

[0046] In order to accurately determine the waveform parameters and frequency changes of the electric field signal, in one embodiment of this application, the feature data of the target object includes the cell size distribution ratio of the target object; correspondingly, the processing module 101 is specifically used to determine the duration of action of the sensitive frequency or sensitive frequency range corresponding to the target cell size within a unit period based on the distribution ratio of the target cell size, so that the duration of action is positively correlated with the distribution ratio of the target cell size, so as to generate waveform parameters for stimulating the target object.

[0047] In this embodiment, the cell distribution ratio of the target object can be determined based on the feature data. The cell distribution ratio of the target object can include the ratio of the number of tumor cells of different sizes to the total number of tumor cells. For example, in one example, the distribution ratio of cell size A is 30%, the distribution ratio of cell size B is 20%, and the distribution ratio of cell size C is 50%. When determining the distribution ratio, the processing module 101 can control the duration of the action of the sensitive frequency or sensitive frequency range corresponding to the target cell size within a unit period based on the distribution ratio of the target cell size, such that the action duration is positively correlated with the distribution ratio of the target cell size. The sensitive frequency range can include fluctuations around the sensitive frequency point corresponding to the target cell size. The positive correlation means that as the distribution ratio of the target cell size increases, the action time increases. In one embodiment, the positive correlation can include a positive correlation coefficient between the action duration and the cell size distribution ratio. For example, in one instance, if the distribution percentage of cell size A is 30%, the distribution percentage of cell size B is 20%, and the distribution percentage of cell size C is 50%, and the unit period of the electric field signal is 60s, then the duration of the sensitive frequency corresponding to cell size A is 18s, the duration of the sensitive frequency corresponding to cell size B is 12s, and the duration of the sensitive frequency corresponding to cell size A is 30s. It should be noted that the frequency change of the electric field signal can be continuous or discrete. In one embodiment of this application, after determining the duration of action corresponding to different cell size distribution percentages, the processing module 101 can fit multiple discrete durations to make the frequency change of the electric field signal continuous.

[0048] Through the above embodiments, the processing module 101 can determine the duration of action of the sensitive frequency or sensitive frequency range corresponding to each cell size based on the proportion of each cell size distribution, making the duration of action positively correlated with the proportion of the size distribution. This allows for a longer duration of action of the sensitive frequency corresponding to cell sizes with a larger proportion of cell size distribution, ensuring that the division of these cells is sufficiently suppressed by the electric field generated by the electric field generating device 100, resulting in a better therapeutic effect. On the other hand, it allows for a shorter duration of action of the sensitive frequency corresponding to cell sizes with a smaller proportion of cell size distribution, thus reducing the harm caused by electric field radiation to the human body while inhibiting cell division, improving the user experience. In summary, the spatial electric field generated by the electric field generating device 100 can improve the inhibition efficiency while effectively suppressing the mitosis of most tumor cells.

[0049] To save computation time and improve the control efficiency of electric field signal frequency changes, in another embodiment of this application, the frequency change can be determined simply and quickly based on the acquired reference frequency and reference frequency range. Specifically, the processing module 101 is further used to acquire the reference frequency and reference frequency range; correspondingly, the processing module 101 is used to generate the waveform parameters for stimulating the target object based on the reference frequency, the frequency change range, and the feature data.

[0050] In this embodiment, the reference frequency can be a reference frequency of the electric field signal, such as a sensitive frequency reference point found by a method of selecting sensitive frequencies based on feature data. For example, the reference frequency can be determined according to the cell type corresponding to the target object. In one example, there are four common types of lung tumor cells: A549, MSTO-211H, NCI-H1299, and NCI-H2052, all of which have a suitable sensitive frequency of 150kHz. Therefore, when the cell type is determined to be lung, the reference frequency can be determined to be 150kHz. It should be noted that the reference frequency can be a reference frequency input by the user through the aforementioned terminal, or it can be a reference frequency determined by the processing module 101 based on the feature data or the proportion of cell size distribution. In one embodiment of this application, the reference frequency range can include the frequency range encompassed by the maximum and minimum frequencies of the electric field signal. The minimum frequency can include a first sensitive frequency corresponding to a cell size smaller than a first preset size threshold. The first preset size threshold can be determined by the user according to actual application needs. For example, the first preset size threshold may include the size corresponding to the largest cell in the target object, or it may be determined based on the sizes of several larger cells in the target object, such as the average, median, etc. After determining the cell size smaller than the first preset threshold, the first sensitive frequency can be determined according to the correspondence between cell size and sensitive frequency. The correspondence can be set by the user based on actual experimental results. The correspondence can be represented using a correspondence table, a correspondence function, or a correspondence model, which is not limited in this application. Correspondingly, the maximum frequency may include the second sensitive frequency corresponding to the cell size greater than the second preset size threshold. The second preset size threshold is determined in the same way as the first preset size threshold, but the values ​​of the first preset size threshold and the second preset size threshold are different, with the first preset size threshold being greater than the second preset size threshold. Of course, in other embodiments of this application, the maximum frequency and the minimum frequency can be set as constant values ​​by the user based on experience and basic theory. For example, the maximum frequency can be set to the reference frequency + 20kHz, and the minimum frequency can be set to the reference frequency - 20kHz. It should be noted that the reference frequency range can be the reference frequency range input by the user through the aforementioned terminal, or the reference frequency range determined by the processing module 101 based on the feature data or the proportion of cell size distribution.

[0051] To improve the efficiency of electric field signal generation and the efficiency of rapid switching between electric field signals of different frequencies, the electric field generating device 100 may include multiple signal generating modules 103, which are used alternately to generate electric field signals with continuously changing frequencies. Specifically, in one embodiment of this application, the number of signal generating modules 103 is multiple, and the multiple signal generating modules 103 are used to generate electric field signals with different waveform parameters; correspondingly, the processing module 101 is used to select a target signal generating module 103 at the time of frequency switching, and the target signal generating module 103 generates an electric field signal of the frequency to be switched before the time of switching.

[0052] In this embodiment, the plurality of signal generation modules 103 can generate electric field signals with different waveform parameters. Specifically, the processing module 101 can send different waveform parameters to different signal generation modules 103, and different signal generation modules 103 can generate corresponding electric field signals according to different waveform parameters. For example, signal generation module 103-A generates electric field signal A, and signal generation module 103-B can generate electric field signal B. The waveform parameters of electric field signal A and electric field signal B can be different. In one embodiment of this application, since the cell type or size of the target object is different, the applicable optimal electric field frequency is also different. Therefore, the frequency parameter in the waveform parameters needs to be switched over time. For example, the frequency of the electric field signal at time t1 is different from the frequency at time t2. Based on this, in order to improve the frequency switching efficiency, the processing module 101 can select the corresponding signal generation module 103 according to the different frequencies. Since the multiple signal generators pre-generate multiple electric field signals with different waveform parameters, the processing module 101 can select a target signal generator module 103 from the multiple signal generator modules 103 at the time of frequency switching. The frequency of the electric field signal generated by the target signal generator module 103 is the same as the frequency to be switched. In one embodiment of this application, the processing module 101 can control the switching of the signal generator module by controlling the on and off of the control switch connected to the signal generator module 103. It is understood that, due to the different characteristic data of the target object, the frequency variation range of the electric field signal is relatively wide. That is to say, the frequency of the electric field signal is diverse within a unit period. If too many signal generator modules 103 are set, it will increase the cost, and the switching efficiency will not meet expectations. Based on this, a fixed number of signal generator modules 103 can be set so that the waveform parameters of the electric field signal generated by the fixed number of signal generator modules 103 change with the time of switching. Specifically, in one example, the electric field generating device 100 includes signal generating modules 103-A and 103-B. With a unit period of 100ms, the frequency of the electric field signal A1 generated by signal generating module 103-A can be set to A1 at the 1ms activation time, and the frequency of the electric field signal B1 generated by signal generating module 103-B can be set to B1. When the activation time is 2ms, the signal generating module 103 can be switched from signal generating module 103-A to signal generating module 103-B, and the frequency of the electric field signal A2 generated by signal generating module 103-A can be set to A2 in advance. Thus, when the activation time is 3ms, the frequency of the electric field signal can be quickly switched to A2 by switching from signal generating module 103-B to signal generating module 103-A. This cyclical switching generates a continuously changing electric field signal with a frequency variation trend that matches the waveform parameters.

[0053] In the above embodiment, multiple signal generation modules 103 can be provided in the electric field generating device 100, and the electric field signals generated by the multiple signal generation modules 103 have different frequencies. In this way, a target signal generation module 103 can be selected from the multiple signal generation modules 103 at the time of frequency switching, so that the frequency of the generated electric field signal meets the treatment requirements and the frequency switching efficiency is improved.

[0054] Of course, in other embodiments of this application, the waveform parameters of the required electric field signal can also be pre-stored in the registers of the signal generation module 103. This allows for the rapid generation of the corresponding electric field signal upon receiving a frequency switching command, thereby further optimizing the therapeutic effect of the electric field generation device 100. Specifically, in one embodiment of this application, the signal generation module 103 includes multiple registers for storing waveform parameters of different electric field signals. The signal generation module 103 is also used to receive a waveform switching command sent by the processing module 101 and select a target register from the multiple registers according to the waveform switching command. The target register stores the waveform parameters of the electric field signal whose frequency to be switched.

[0055] In this embodiment, the signal generation module 103 may include multiple registers, which can receive and store waveform parameters sent by the processing module 101 in advance. The processing module 101 can send a waveform switching instruction according to actual treatment needs or time changes within a unit cycle. The waveform switching instruction may include the waveform parameters to be switched. After receiving the waveform switching instruction, the signal generation module 103 can determine the target register corresponding to the waveform parameters included in the waveform switching instruction from the multiple registers. That is, the target register stores the waveform parameters corresponding to the waveform switching instruction. In one embodiment of this application, the processing module 101 can send the waveform switching instruction through the FSELECT pin between itself and the signal generation module 103. It is understood that after selecting the target register, the signal generation module 103 can control the target register to generate a corresponding electric field signal according to the pre-stored waveform parameters for subsequent electric field signal processing.

[0056] In one embodiment of this application, the electric field generating device 100 further includes a visual parameter configuration interface, which is used to provide users with the authority to input reference waveform parameters and / or characteristic data of the target object.

[0057] In this embodiment, the visual logic configuration interface may include multiple data input boxes, each labeled with its corresponding function. Users can then fill the input boxes with corresponding reference waveform parameters or feature data as needed. The visual logic configuration interface may also include controls, such as "OK" buttons to trigger user interaction. Alternatively, the interface may store and display parameters in a table format; this application does not impose any limitations on this. The visual logic configuration interface can be displayed on a client or the aforementioned terminal; this application does not impose any limitations on this. Specifically, in one example, such as... Figure 5 As shown, the visualization parameter configuration interface 500 can be used to provide users with the permission to input characteristic data of target objects such as cell type and cell size, and can also provide users with the permission to input waveform parameters such as reference frequency and output power.

[0058] Through the above embodiments, reference waveform parameters and / or feature data of the target object can be obtained through the visual logic configuration interface, making the subsequent determination of waveform parameters simpler and increasing the user experience.

[0059] In practical applications, during the application of the electric field component 105 to the target object, the electric field generates heat on the contact surface, causing the surface temperature to gradually rise. Considering that the human or animal body has a certain maximum tolerance temperature, if the temperature of the skin surface exceeds this maximum tolerance temperature, it may cause discomfort, thereby reducing the human or animal's experience. Based on this, in one embodiment of this application, the electric field generating device 100 further includes a temperature sensor connected to the electric field component 105. The temperature sensor is connected to the processing module 101 and is used to send the collected temperature of the electric field component 105 to the processing module 101. Correspondingly, when the processing module 101 determines that the temperature is greater than a preset temperature threshold, it stops outputting the waveform parameters used to stimulate the target object; correspondingly, the signal generating module 103 stops outputting the electric field signal used to stimulate the target object.

[0060] In this embodiment of the application, a temperature sensor may be provided in the electric field generating device 100. For example, in one example, such as Figure 4As shown, when the electric field action component 105 is an electrode patch, the temperature sensor 1013 can be placed close to the electrode patch to collect the temperature generated by the electrode patch. The temperature sensor 1013 may include a thermistor, a resistance temperature detector (RTD), a thermocouple, etc. In one embodiment of this application, the temperature sensor 1013 is connected to the processing module 101 to send the collected temperature of the electric field action component 105 to the processing module 101. The temperature can be a specific numerical value such as 35 degrees Celsius, 36 degrees Celsius, 37 degrees Celsius, etc., or a temperature level such as medium temperature, high temperature, etc. The processing module 101 can determine in real time whether the received temperature is greater than a preset temperature threshold, and stop the output in time to prevent burns if the temperature exceeds the preset temperature threshold. The preset temperature threshold can be set by the user according to the actual application scenario and common sense, for example, it can be set to 41 degrees Celsius. It is understood that when the processing module 101 determines that the temperature collected by the temperature sensor is less than the preset temperature threshold or the set temperature, such as 36 degrees Celsius, it can re-output waveform parameters to generate an electric field signal.

[0061] Furthermore, in one embodiment of this application, the electric field action component 105 includes at least one set of electrode patches, each set of electrode patches being attached to the surface of the target object in different directions to receive the electric field signal and form a spatial electric field that can penetrate the target object.

[0062] In this embodiment, two electrode patches in a set of electrode patches are positioned relative to each other on the target object, forming a spatial electric field that penetrates the target object. In one embodiment of this application, to improve the coverage, flexibility, or adaptability of the spatial electric field on the target object, each set of electrodes can be attached to the surface of the target object in different directions to form a spatial electric field that penetrates the target object in different directions. For example, ... Figure 4 As shown, electrode patches B and D can be attached to the surface of the target object relative to each other in the x-axis direction; electrode patches A and C can be attached to the surface of the target object relative to each other in the y-axis direction.

[0063] The flowcharts and block diagrams in the accompanying drawings illustrate the architecture, functionality, and operation of possible implementations of apparatuses, systems, and methods according to various embodiments of this application. In this regard, each block in a flowchart or block diagram may represent a module, segment, or portion of an instruction containing one or more executable instructions for implementing a specified logical function. In some alternative implementations, the functions marked in the blocks may occur in a different order than those shown in the drawings. For example, two consecutive blocks may actually be executed substantially in parallel, and they may sometimes be executed in reverse order, depending on the functions involved.

[0064] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. An electric field generating device, characterized by comprising: It includes a processing module, a signal generation module, and at least one electric field application component connected in sequence, wherein, The processing module is used to acquire feature data of the target object and generate waveform parameters for stimulating the target object based on the feature data; The signal generation module is used to generate an electric field signal that matches the waveform parameters; The at least one electric field-acting component is used to receive the electric field signal to form a spatial electric field acting on the target object; The characteristic data of the target object includes the distribution ratio of cell size of the target object; correspondingly, the processing module is specifically used to determine the duration of action of the sensitive frequency or sensitive frequency range corresponding to the target cell size within a unit period based on the distribution ratio of the target cell size, so that the duration of action is positively correlated with the distribution ratio of the target cell size, so as to generate waveform parameters for stimulating the target object.

2. The electric field generating device of claim 1, wherein The electric field generating device is coupled to the terminal and is used to receive feature data of the target object.

3. The electric field generating device according to claim 2, characterized in that, The terminal is also used to receive reference waveform parameters input by the user; correspondingly, the processing module is also used to generate waveform parameters for stimulating the target object based on the feature data and the reference waveform parameters.

4. The electric field generating device according to claim 1, characterized in that, The number of signal generation modules is multiple, and the multiple signal generation modules are used to generate electric field signals with different waveform parameters; correspondingly, the processing module is used to select a target signal generation module at the time of frequency switching, and the target signal generation module generates an electric field signal of the frequency to be switched before the time of switching.

5. The electric field generating device according to claim 1, characterized in that, The signal generation module includes multiple registers for storing waveform parameters of different electric field signals. The signal generation module is also used to receive waveform switching instructions sent by the processing module and select a target register from the multiple registers according to the waveform switching instructions. The target register stores waveform parameters of the electric field signal with the frequency to be switched.

6. The electric field generating device according to claim 1, characterized in that, The processing module is also used to obtain a reference frequency and a reference frequency range; correspondingly, the processing module is used to generate the waveform parameters for stimulating the target object based on the reference frequency, the reference frequency range and the feature data.

7. The electric field generating device according to claim 1, characterized in that, The electric field generating device also includes a visual parameter configuration interface, which is used to provide users with the authority to input reference waveform parameters and / or characteristic data of the target object.

8. The electric field generating device according to claim 1, characterized in that, The electric field generating device further includes a temperature sensor connected to the electric field acting component. The temperature sensor is connected to the processing module and is used to send the collected temperature of the electric field acting component to the processing module. Correspondingly, when the processing module determines that the temperature is greater than a preset temperature threshold, it stops outputting the waveform parameters used to stimulate the target object. Correspondingly, the signal generating module stops outputting the electric field signal used to stimulate the target object.

9. The electric field generating device according to claim 1, characterized in that, The electric field action component includes at least one set of electrode patches, each set of electrode patches being attached to the surface of the target object in different directions to receive the electric field signal and form a spatial electric field that can penetrate the target object.

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