An electromagnetic field detection system

Abstract

The application discloses an electromagnetic field detection system, which comprises a controller, a data acquisition device, a detection electrode device, a gauss meter and a containing device; the controller is electrically connected with the data acquisition device; the data acquisition device is electrically connected with the detection electrode device and / or the gauss meter; the containing device is used for storing a solution to be detected; the detection electrode device comprises an electrode support and a fixing support, and a first electrode plate and a second electrode plate are movably connected to the electrode support; the gauss meter comprises a signal processing circuit and a detection probe; the electrode support and / or the detection probe are connected to the fixing support; wherein the fixing support is used for fixing the electrode support and / or the detection probe; the gauss meter is used for detecting a magnetic field in an alternating magnetic acoustic coupling stimulation technology; and the detection electrode device is used for detecting an electric field in the alternating magnetic acoustic coupling stimulation technology. By adopting the technical scheme, the electric field and the magnetic field can be determined and stored at the position, and then the electric field distribution and the magnetic field distribution in a three-dimensional space can be determined.

Description

Technical Field

[0001] This invention relates to the field of electromagnetic field detection technology, and in particular to an electromagnetic field detection system. Background Technology

[0002] In recent years, non-invasive brain stimulation techniques in the field of neuroscience have developed rapidly. Transcranial magnetoacoustic stimulation (M-TMAS) with alternating magnetic fields is a novel multi-physics field coupling non-invasive brain stimulation technique. M-TMAS technology replaces the static magnetic field in traditional transcranial magnetoacoustic stimulation (TMAS) systems with an alternating magnetic field generated by an alternating coil in transcranial magnetic stimulation (TMS), combining TMS and TMAS to enhance the electric field intensity of stimulation on target brain regions. In M-TMAS, the alternating magnetic field can instantaneously achieve a magnetic induction intensity as high as 1-3T, thereby increasing the magnetoacoustic coupling electric field intensity; furthermore, the magnetic induction electric field generated by the alternating magnetic field is in the same direction as the magnetoacoustic coupling electric field, further enhancing the stimulation electric field intensity of the target area. Therefore, achieving electric field measurement is of great significance for precise whole-brain neuromodulation techniques, including those targeting deep brain regions.

[0003] Electromagnetic field detection systems are a key factor in evaluating the performance of brain stimulation techniques. With the increasing complexity of multi-physics coupling, the expansion of the detection space, the rising requirements for detection accuracy, the need for stable electric field detection, and the detection of electrical signals from multiple angles, the demand for high-performance electromagnetic field detection systems in scientific research is growing. However, due to the innovative nature of alternating magnetic field transcranial magnetoacoustic stimulation (TMS), there has been limited research on electromagnetic field detection for this technology both domestically and internationally. Summary of the Invention

[0004] This invention provides an electromagnetic field detection system for detecting electric and magnetic fields in transcranial magnetoacoustic stimulation (TMS) technology using alternating magnetic fields.

[0005] According to one aspect of the present invention, an electromagnetic field detection system is provided, the electromagnetic field detection system comprising: a controller, a data acquisition device, a detection electrode device, a gaussmeter, and a receiving device;

[0006] The controller is electrically connected to the data acquisition device; the data acquisition device is electrically connected to the detection electrode device and / or the gaussmeter; the container is used to store the solution to be tested;

[0007] The detection electrode device includes an electrode support and a fixed support, with the electrode support movably connected to a first electrode plate and a second electrode plate; the gaussmeter includes a signal processing circuit and a detection probe; the electrode support and / or the detection probe are connected to the fixed support; wherein, the fixed support is used to fix the electrode support and / or the detection probe; the gaussmeter is used to detect the magnetic field in the alternating magnetoacoustic coupling stimulation technique; the detection electrode device is used to detect the electric field in the alternating magnetoacoustic coupling stimulation technique.

[0008] Optionally, the fixing bracket includes a rotating slot interface, and one end of the electrode bracket and / or the detection probe is connected to the rotating slot interface; wherein, the rotating slot interface is a square interface; the electrode bracket and / or the detection probe includes a quadrangular prism portion; the square interface is used to accommodate the quadrangular prism portion.

[0009] Optionally, the fixing bracket includes a rotating slot interface, and one end of the electrode bracket and / or the detection probe is connected to the rotating slot interface; wherein, the rotating slot interface is a circular interface; the electrode bracket and / or the detection probe includes a cylindrical portion; the circular interface is used to accommodate the cylindrical portion.

[0010] Optionally, the fixing bracket includes a rotating slot interface, and one end of the electrode bracket and / or the detection probe is connected to the rotating slot interface; the rotating slot interface is a superimposed interface of a circular interface and a square interface; wherein, the diameter of the circular interface is larger than the side length of the square interface, and the diagonal length of the square interface is larger than the diameter of the circular interface;

[0011] The electrode holder and / or the detection probe includes a cylindrical portion, and the circular interface is used to accommodate the cylindrical portion; the electrode holder and / or the detection probe includes a prism portion, and the square interface is used to accommodate the prism portion.

[0012] Optionally, the electromagnetic field detection system further includes: a motor device;

[0013] The controller is electrically connected to the motor device; the motor device is mechanically connected to the fixed bracket; the motor device is used to drive the fixed bracket to move according to the electrical signal from the controller.

[0014] Optionally, the controller is electrically connected to the alternating magnetic field excitation device; the controller is also electrically connected to the pulsed ultrasonic excitation device;

[0015] The alternating magnetic field excitation device is used to control the alternating coil to generate an alternating magnetic field according to the electrical signal of the controller; the pulsed ultrasound excitation device is used to control the ultrasonic transducer to generate a focused ultrasonic pulse signal according to the electrical signal of the controller.

[0016] Optionally, the electromagnetic field detection system further includes: a coil holder;

[0017] The coil holder is mechanically connected to the motor device; the coil holder is used to fix the alternating coil; the motor device is also used to drive the coil holder to move according to the electrical signal of the controller.

[0018] Optionally, the electromagnetic field detection system further includes: a transducer fixer;

[0019] The transducer retainer is mechanically connected to the motor device; the transducer retainer is used to fix the ultrasonic transducer; the motor device is also used to drive the transducer retainer to move according to the electrical signal of the controller.

[0020] Optionally, the electromagnetic field detection system further includes: a gain amplifier;

[0021] The input terminal of the gain amplifier is electrically connected to the output terminal of the detection electrode device; the output terminal of the gain amplifier is electrically connected to the input terminal of the data acquisition device.

[0022] Optionally, the electromagnetic field detection system further includes: a bandpass filter;

[0023] The input terminal of the bandpass filter is electrically connected to the output terminal of the detection electrode device; the output terminal of the bandpass filter is electrically connected to the input terminal of the data acquisition device.

[0024] The technical solution of the present invention can acquire the potential on the first electrode plate, the second electrode plate, and the detection probe by setting up a detection electrode device, a gaussmeter, and a data acquisition device, and transmit the potential signal to the controller. The controller can determine the electric field and magnetic field based on the potential signal and store the electric field and magnetic field at that location, thereby determining the electric field distribution and magnetic field distribution in three-dimensional space.

[0025] It should be understood that the description in this section is not intended to identify key or essential features of the embodiments of the present invention, nor is it intended to limit the scope of the invention. Other features of the invention will become readily apparent from the following description. Attached Figure Description

[0026] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0027] Figure 1This is a schematic diagram of an M-TMAS technology provided in an embodiment of the present invention;

[0028] Figure 2 This is a schematic diagram of the structure of an electromagnetic field detection system provided in an embodiment of the present invention;

[0029] Figure 3 This is a schematic diagram of the structure of a detection electrode device provided in an embodiment of the present invention;

[0030] Figure 4 A schematic diagram of a gaussmeter provided in an embodiment of the present invention;

[0031] Figure 5 This is a schematic diagram of a fixed bracket provided in an embodiment of the present invention;

[0032] Figure 6 This is a schematic diagram of electromagnetic field detection in two orthogonal directions provided in an embodiment of the present invention;

[0033] Figure 7 This is a schematic diagram of another type of fixed bracket provided in an embodiment of the present invention;

[0034] Figure 8 This is a schematic diagram of another type of fixed bracket provided in an embodiment of the present invention;

[0035] Figure 9 This is a schematic diagram of the structure of another electromagnetic field detection system provided in an embodiment of the present invention;

[0036] Figure 10 This is a schematic diagram of another electromagnetic field detection system provided in an embodiment of the present invention. Detailed Implementation

[0037] To enable those skilled in the art to better understand the present invention, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of the present invention.

[0038] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this invention are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of the invention described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover a non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0039] Figure 1 This is a schematic diagram of an M-TMAS technique provided in an embodiment of the present invention. M-TMAS is a non-invasive neurostimulation technique based on the magnetoacoustic coupling effect of conductive tissue. (Reference) Figure 1 Conductive particles in solution 001 vibrate under focused ultrasound excitation 002. Under the influence of an alternating magnetic field B generated by an alternating coil 003 perpendicular to the particle vibration direction, the conductive particles experience a Lorentz force. Positive and negative particles deflect and converge along the vector product of the alternating magnetic field B and the ultrasonic field V, forming an internal magnetoacoustic coupled focused electric field EMA. This is then superimposed with a magnetically induced electric field EM generated in the same direction by the alternating magnetic field, such as... Figure 1 The figure shows the final stimulation electric field generated by M-TMAS. According to the principle of M-TMAS, the distribution and superposition of the three physical fields—magnetoacoustic coupling electric field, magnetic induction electric field, and alternating magnetic field—determine the actual stimulation intensity and stimulation focal size of M-TMAS. Therefore, the measurement of the magnetoacoustic coupling electric field, magnetic induction electric field, and alternating magnetic field in M-TMAS is crucial to M-TMAS technology.

[0040] This invention provides an electromagnetic field detection system that can measure the electric field strength and magnetic induction intensity in space using M-TMAS technology. Figure 2 This is a schematic diagram of an electromagnetic field detection system provided in an embodiment of the present invention, with reference to... Figure 2 The electromagnetic field detection system includes a controller 01, a data acquisition device 02, a detection electrode device 03, a gaussmeter 04, and a container 05. The controller 01 is electrically connected to the data acquisition device 02. The data acquisition device 02 is electrically connected to the detection electrode device 03 and / or the gaussmeter 04. The container 05 is used to store the solution to be tested.

[0041] Figure 3 This is a schematic diagram of a detection electrode device provided in an embodiment of the present invention. Figure 4 This is a schematic diagram of a gaussmeter provided in an embodiment of the present invention. (Reference) Figure 3 and Figure 4 The detection electrode device 03 includes an electrode support 31 and a fixed support 32. The electrode support 31 is movably connected to the first electrode plate 301 and the second electrode plate 302. The gaussmeter 04 includes a signal processing circuit 41 and a detection probe 42. The electrode support 31 and / or the detection probe 42 are connected to the fixed support 32. The fixed support 32 is used to fix the electrode support 31 and / or the detection probe 42. The gaussmeter 04 is used to detect the magnetic field in alternating magnetoacoustic coupling stimulation technology (M-TMAS). The detection electrode device 03 is used to detect the electric field in M-TMAS.

[0042] For example, during electric field detection, the detection electrode device 03 is placed in the test solution in the container 05. Under the action of an external stimulation electric field, positive and negative ions converge on the first electrode plate 301 and the second electrode plate 302, respectively, forming a potential difference. The signals on the first electrode plate 301 and the second electrode plate 302 are acquired by the data acquisition device 02 and stored and processed by the controller 01 to determine the real-time electric field. The controller 01 can be, for example, a computer. During electric field detection, the test solution in the container 05 is emptied, and the detection probe 42 of the gaussmeter 04 is fixed on the fixing bracket 32. The signal on the detection probe 42 can be amplified and processed by the signal processing circuit 41 before being transmitted to the data acquisition device 02. Similarly, the controller 01 stores and processes the data to determine the real-time magnetic field.

[0043] In this embodiment of the invention, by setting up a detection electrode device, a gaussmeter, and a data acquisition device, the potential on the first electrode plate, the second electrode plate, and the detection probe can be acquired, and the potential signal can be transmitted to the controller. The controller can determine the electric field and magnetic field based on the potential signal and store the electric field and magnetic field at that location, thereby determining the electric field distribution and magnetic field distribution in three-dimensional space.

[0044] Optional, Figure 5 This is a schematic diagram of a fixed bracket provided in an embodiment of the present invention, with reference to... Figure 5 The fixed bracket 32 ​​includes a rotating slot interface 321, and one end of the electrode bracket 31 and / or the detection probe 42 is connected to the rotating slot interface 321. The rotating slot interface is a square interface, and the electrode bracket 31 and / or the detection probe 42 includes a quadrangular prism portion; the square interface is used to accommodate the quadrangular prism portion.

[0045] For example, Figure 6 This is a schematic diagram of electromagnetic field detection in two orthogonal directions provided in an embodiment of the present invention, with reference to... Figure 6 When the quadrangular prism portion of the electrode holder 31 and / or the detection probe 42 is inserted into the rotating slot interface 321, electromagnetic field detection in two orthogonal directions can be accurately achieved through the square interface and the quadrangular prism portion.

[0046] Optional, Figure 7 This is a schematic diagram of another type of fixing bracket provided in an embodiment of the present invention, with reference to... Figure 7 The fixed bracket 32 ​​includes a rotating slot interface 321, and one end of the electrode bracket 31 and / or the detection probe 42 is connected to the rotating slot interface 321. The rotating slot interface 321 is a circular interface, and the electrode bracket 31 and / or the detection probe 42 includes a cylindrical portion; the circular interface is used to accommodate the cylindrical portion.

[0047] For example, the cylindrical portion of the electrode holder 31 and / or the detection probe 42 can be inserted into the circular interface of the rotating slot interface 321 of the fixed bracket 32. The electrode holder 31 and / or the detection probe 42 can be fixed on the fixed bracket 20 and rotate within the rotating slot interface 21, so that the detection electrode device 03 and / or the gaussmeter 04 can realize electromagnetic field detection at any angle.

[0048] Optional, Figure 8 This is a schematic diagram of another type of fixing bracket provided in an embodiment of the present invention, with reference to... Figure 8 The rotating slot interface 321 is a superimposed interface of a circular interface and a square interface; wherein, the diameter d of the circular interface is greater than the side length L of the square interface, and the diagonal length D of the square interface is greater than the diameter d of the circular interface. In this way, the detection electrode device 03 and / or the gaussmeter 04 can accurately realize electromagnetic field detection in two orthogonal directions, and can also realize electromagnetic field detection at any angle.

[0049] Optional, Figure 9 This is a schematic diagram of another electromagnetic field detection system provided in an embodiment of the present invention. (Reference) Figure 9 The electromagnetic field detection system also includes a motor device 06, and the controller 01 is electrically connected to the motor device 06; the motor device 06 is mechanically connected to the fixed bracket 32; the motor device 06 is used to drive the fixed bracket 32 ​​to move according to the electrical signal of the controller 01.

[0050] For example, the fixed bracket 32 ​​can be fixed to the three-dimensional moving bracket using the threaded hole 322. The motor device 06 includes a motor, which drives the fixed bracket 32 ​​to move along the first direction x, the second direction y, or the third direction z according to the motor control signal output by the controller 01, thereby realizing electromagnetic field detection at any position. The motor device 06 can drive the fixed bracket 32 ​​to move according to a preset rule, thereby enabling the detection electrode device 03 and / or the gaussmeter 04 to perform three-dimensional spatial scanning detection to determine the three-dimensional vector distribution of the electromagnetic field. The first direction x, the second direction y, and the third direction z intersect each other.

[0051] Optional, continue to refer to Figure 9The electromagnetic field detection system also includes a gain amplifier 21; the input terminal of the gain amplifier 21 is electrically connected to the output terminal of the detection electrode device 03; the output terminal of the gain amplifier 21 is electrically connected to the input terminal of the data acquisition device 02.

[0052] For example, the electrical signal detected by the detection electrode device 03 can be amplified by a variable gain amplifier of 0-90dB, which enables the electromagnetic field detection system to be applicable to the measurement of magnetic induction electric fields and magnetoacoustic coupling electric fields of different magnitudes at the same time. It can more accurately detect magnetic induction electric fields and magnetoacoustic coupling electric fields in the same spatial position and in the same vector direction, thereby improving the detection resolution.

[0053] Optional, continue to refer to Figure 9 The electromagnetic field detection system also includes a bandpass filter 22; the input terminal of the bandpass filter 22 is electrically connected to the output terminal of the detection electrode device 03; the output terminal of the bandpass filter 22 is electrically connected to the input terminal of the data acquisition device 02. For example, the amplified electrical signal enters the bandpass filter 22 for filtering, which can filter out low-frequency baseline drift and high-frequency noise.

[0054] Figure 10 This is a schematic diagram of another electromagnetic field detection system provided in an embodiment of the present invention, with reference to... Figure 10 The controller 01 is electrically connected to the alternating magnetic field excitation device 11; the controller 01 is also electrically connected to the pulsed ultrasonic excitation device 12; the alternating magnetic field excitation device 11 is used to control the alternating coil 111 to generate an alternating magnetic field according to the electrical signal of the controller 01; the pulsed ultrasonic excitation device 12 is used to control the ultrasonic transducer 121 to generate a focused ultrasonic pulse signal according to the electrical signal of the controller 01.

[0055] For example, the alternating magnetic field excitation device 11 can be implemented by a transcranial magnetic stimulation (TMS) device. The alternating magnetic field excitation device can generate an alternating current with a certain repetition frequency (e.g., 1 Hz) and a certain pulse width (e.g., 280 μs) to excite the alternating coil. Based on the electromagnetic induction theory, the alternating coil 111 can generate an alternating magnetic field and an induced electric field with a 1 Hz repetition frequency and 280 μs. The ultrasound transducer 121 includes a single-element focusing transducer or a phased array focusing ultrasound transducer, and the frequency can be selected based on the stimulation depth of the target object. The pulsed ultrasound excitation device 12 can provide excitation for the focused ultrasound transducer. The number of channels of the excitation source is consistent with the number of transducer elements to ensure that each channel can excite each element individually. The excitation parameters of each channel of the multi-channel pulsed ultrasound excitation source can be controlled by the controller 01. By adjusting the pulse excitation parameters of each channel through the controller 01, the ultrasound transducer 121 can emit a focused ultrasound pulse signal with adjustable focal length and focal position. The controller 01 can also control the alternating magnetic field excitation device 11 and the pulsed ultrasonic excitation device 12 to work together with the data acquisition device 02, so as to avoid the situation where only the alternating magnetic field excitation device 11 and / or the pulsed ultrasonic excitation device 12 work while the data acquisition device 02 does not work, or only the data acquisition device 02 works while the alternating magnetic field excitation device 11 and / or the pulsed ultrasonic excitation device 12 does not work, thereby reducing energy consumption and saving energy.

[0056] Optionally, the electromagnetic field detection system also includes a coil holder (not shown in the figure); the coil holder is mechanically connected to the motor device; the coil holder is used to fix the alternating coil; the motor device is also used to drive the coil holder to move according to the electrical signal of the controller. The coil holder can realize the movement of the alternating coil in three-dimensional space and the adjustment of the coil angle, which is convenient for detection electrode device 03 and / or gaussmeter 04 to perform detection.

[0057] Optionally, the electromagnetic field detection system also includes a transducer holder (not shown in the figure); the transducer holder is mechanically connected to the motor device; the transducer holder is used to fix the ultrasonic transducer; the motor device is also used to drive the transducer holder to move according to the electrical signal of the controller. The transducer holder can realize the movement of the ultrasonic transducer in three-dimensional space and the adjustment of the ultrasonic transducer angle, which is convenient for detection electrode device 03 and / or gaussmeter 04 to perform detection.

[0058] Note that the above description is merely a preferred embodiment of the present invention and the technical principles employed. Those skilled in the art will understand that the present invention is not limited to the specific embodiments described herein, and various obvious changes, readjustments, and substitutions can be made without departing from the scope of protection of the present invention. Therefore, although the present invention has been described in detail through the above embodiments, the present invention is not limited to the above embodiments, and may include many other equivalent embodiments without departing from the concept of the present invention, the scope of which is determined by the scope of the appended claims.

Claims

1. An electromagnetic field detection system, characterized in that, The electromagnetic field detection system includes: a controller, a data acquisition device, a detection electrode device, a gaussmeter, and a container. The controller is electrically connected to the data acquisition device; the data acquisition device is electrically connected to the detection electrode device and / or the gaussmeter; the container is used to store the solution to be tested; The detection electrode device includes an electrode support and a fixed support, with the electrode support movably connected to a first electrode plate and a second electrode plate; the gaussmeter includes a signal processing circuit and a detection probe; the electrode support and / or the detection probe are connected to the fixed support; wherein, the fixed support is used to fix the electrode support and / or the detection probe; the gaussmeter is used to detect the magnetic field in the alternating magnetoacoustic coupling stimulation technique; the detection electrode device is used to detect the electric field in the alternating magnetoacoustic coupling stimulation technique; The fixed bracket includes a rotating slot interface, and one end of the electrode bracket and / or the detection probe is connected to the rotating slot interface; the rotating slot interface is a superimposed interface of a circular interface and a square interface; wherein, the diameter of the circular interface is larger than the side length of the square interface, and the diagonal length of the square interface is larger than the diameter of the circular interface; The electrode holder and / or the detection probe both include a cylindrical portion and a prism portion; the cylindrical portion can be inserted into the circular interface to achieve electromagnetic field detection at any angle; the prism portion can be inserted into the square interface to accurately achieve electromagnetic field detection in two orthogonal directions.

2. The electromagnetic field detection system according to claim 1, characterized in that, The electromagnetic field detection system also includes: a motor device; The controller is electrically connected to the motor device; the motor device is mechanically connected to the fixed bracket; the motor device is used to drive the fixed bracket to move according to the electrical signal from the controller.

3. The electromagnetic field detection system according to claim 2, characterized in that, The controller is electrically connected to the alternating magnetic field excitation device; the controller is also electrically connected to the pulsed ultrasonic excitation device; The alternating magnetic field excitation device is used to control the alternating coil to generate an alternating magnetic field according to the electrical signal of the controller; the pulsed ultrasound excitation device is used to control the ultrasonic transducer to generate a focused ultrasonic pulse signal according to the electrical signal of the controller.

4. The electromagnetic field detection system according to claim 3, characterized in that, The electromagnetic field detection system also includes: a coil holder; The coil holder is mechanically connected to the motor device; the coil holder is used to fix the alternating coil; the motor device is also used to drive the coil holder to move according to the electrical signal of the controller.

5. The electromagnetic field detection system according to claim 3, characterized in that, The electromagnetic field detection system also includes: a transducer fixer; The transducer retainer is mechanically connected to the motor device; the transducer retainer is used to fix the ultrasonic transducer; the motor device is also used to drive the transducer retainer to move according to the electrical signal of the controller.

6. The electromagnetic field detection system according to claim 1, characterized in that, The electromagnetic field detection system also includes: a gain amplifier; The input terminal of the gain amplifier is electrically connected to the output terminal of the detection electrode device; the output terminal of the gain amplifier is electrically connected to the input terminal of the data acquisition device.

7. The electromagnetic field detection system according to claim 1, characterized in that, The electromagnetic field detection system also includes: a bandpass filter; The input terminal of the bandpass filter is electrically connected to the output terminal of the detection electrode device; the output terminal of the bandpass filter is electrically connected to the input terminal of the data acquisition device.

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