Intraocular lens platform with improved haptics force distribution

Abstract

The present disclosure relates to an intraocular lens platform with improved haptics force distribution. An ophthalmic lens comprising an optic including an anterior surface, a posterior surface, and an optic edge extending between the anterior surface and the posterior surface, the optic having an optical axis. The ophthalmic lens further comprises: a plurality of haptics extending from a periphery of the optic, each of the plurality of haptics including a gusset region, a distal region, and an elbow region connecting the gusset region to the distal region. The gusset region of each of the plurality of haptics extends from the periphery of the optic and spans a portion of the periphery of the optic. Further, a thickness of the gusset region of each of the plurality of haptics monotonically increases as a distance from the periphery of the optic increases, and a thickness of the distal region of each of the plurality of haptics monotonically decreases as a distance from the elbow region increases.

Description

[0001] This application is a divisional application of the application filed on December 18, 2018, with application number 201880081718.4 and invention title "Intraocular Lens Platform with Improved Tactile Force Distribution". Technical Field

[0002] This disclosure generally relates to an ophthalmic lens, and more specifically to an intraocular lens platform with improved tactile force distribution. Background Technology

[0003] In its simplest sense, the human eye functions to provide vision by allowing light to pass through a transparent outer part called the cornea and focusing an image onto the retina using the lens. The quality of the focused image depends on many factors, including the size and shape of the eye, as well as the transparency of the cornea and lens. When aging or disease causes the lens to become less transparent, vision deteriorates because less light can pass through to the retina. This defect in the eye's lens is medically known as a cataract. One accepted treatment for this condition is surgical removal of the lens and replacement of its function with an intraocular lens (IOL).

[0004] Typically, an IOL comprises: (1) an optics device that corrects the patient's vision (e.g., typically through refraction or diffraction); and (2) haptic loops that form a support structure holding the optics device in place within the patient's eye (e.g., within the capsular bag). Generally, the physician selects an IOL whose optics have appropriate corrective properties for the patient. During the procedure, the surgeon implants the selected IOL by making an incision (capsulotomy) in the capsular bag of the patient's eye and inserting the IOL through the incision. Typically, the IOL is folded to be inserted into the capsular bag via the corneal incision and unfolded once in place within the capsular bag. During unfolding, the haptic loops can expand such that a small portion of each haptic loop contacts the capsular bag, holding the IOL in place.

[0005] While existing IOLs function well in many patients, they also have certain drawbacks. For example, existing IOL designs may include loops that create scarring or wrinkling in the posterior capsule. Such scarring may be due to a relatively small contact angle between the loop and the capsule, which can lead to uneven force distribution around the capsule. Because scarring can adversely affect patient outcomes (e.g., by providing a mechanism for cell growth and / or migration, causing posterior capsule opacification (PCO)), loop designs that reduce scarring are needed. Furthermore, such designs should also have volume and foldability that help maintain a small to acceptable incision size, as larger incisions can adversely affect patient recovery.

[0006] Therefore, there is a need for an IOL whose loop design reduces scratches (which is one reason for addressing PCO) without adversely affecting rotational or axial stability or significantly complicating implantation. Summary of the Invention

[0007] In some embodiments, the ophthalmic lens includes an optics element comprising an anterior surface, a rear surface, and an optical edge extending between the anterior and rear surfaces, the optics element having an optical axis. The ophthalmic lens further includes a plurality of loops extending from the periphery of the optics element, each of the plurality of loops including a gusset region, a distal region, and a bend region connecting the gusset region to the distal region. The gusset region of each of the plurality of loops extends from the periphery of the optics element and crosses a portion of the periphery of the optics element. Furthermore, the thickness of the gusset region of each of the plurality of loops monotonically increases with increasing distance from the periphery of the optics element, while the thickness of the distal region of each of the plurality of loops monotonically decreases with increasing distance from the bend region.

[0008] In some embodiments, this disclosure may provide one or more technical advantages. For example, the IOL platform described herein can improve the uniformity of tactile force distribution, thereby reducing posterior pouch wrinkles (marks) while maintaining axial and rotational stability for most pouch sizes. More specifically, the IOL platform described herein can improve the uniformity of tactile force distribution by providing a larger (in some embodiments, greater than 50 degrees) contact angle compared to current one-piece IOLs (whose contact angle can be between 40 and 45 degrees). Attached Figure Description

[0009] To gain a more thorough understanding of this disclosure and its advantages, reference is now made to the following description taken in conjunction with the accompanying drawings, in which similar reference numerals indicate similar features, and in the drawings:

[0010] Figure 1 A top view of an exemplary ophthalmic lens according to certain embodiments of the present disclosure is shown;

[0011] Figure 2 Showing Figure 1 A cross-sectional view of the optical components of an exemplary ophthalmic lens depicted in the figure (along...) Figure 1 (Line AA in the middle);

[0012] Figure 3 Showing Figure 1 A detailed view of the optical component edge of an exemplary ophthalmic lens depicted in the image;

[0013] Figure 4 Showing Figure 1A cross-sectional view of the loop of an exemplary ophthalmic lens depicted in the figure (along...) Figure 1 (The line BB in the middle)

[0014] Figure 5 Showing Figure 1 A cross-sectional view of the optics and loop of an exemplary ophthalmic lens depicted in the figure (along...) Figure 1 (CC line in the middle);

[0015] Figure 6 Showing Figure 1 Detailed cross-sectional views of the optics and loops of an exemplary ophthalmic lens depicted in the figure; and

[0016] Figure 7 Showing Figure 1 A detailed view of the gusset plate area of ​​an exemplary ophthalmic lens depicted in the image.

[0017] Those skilled in the art will understand that the following figures are for illustrative purposes only. The figures are not intended to limit the scope of the applicant's disclosure in any way. Detailed Implementation

[0018] In general, this disclosure relates to an ophthalmic lens (e.g., an IOL) that is rotationally and axially stable and reduces posterior capsule streaking. More specifically, this disclosure provides an ophthalmic lens including an optics element having an anterior surface, a posterior surface, and an optical edge extending between the anterior and posterior surfaces, the optics element having an optical axis. The ophthalmic lens further includes a plurality of loops extending from the periphery of the optics element, each of the plurality of loops including a gusset region, a distal region, and a bend region connecting the gusset region to the distal region. The gusset region of each of the plurality of loops extends from the periphery of the optics element and crosses a portion of the periphery of the optics element. Furthermore, the thickness of the gusset region of each of the plurality of loops monotonically increases with increasing distance from the periphery of the optics element, while the thickness of the distal region of each of the plurality of loops monotonically decreases with increasing distance from the bend region.

[0019] Figures 1 to 7 Different views of an ophthalmic lens 100 (hereinafter referred to as IOL 100) according to certain embodiments of the present disclosure are shown. IOL 100 may include an optics element 102 and a plurality of loops 104. Specifically, Figure 1 A top view of IOL 100 is shown. Figure 2 A cross-sectional view of the optical device 102 of 100 is shown (along...) Figure 1 (Line AA in the middle) Figure 3 A detailed view of the optical component edge 114 of the IOL100 is shown. Figure 4 A cross-sectional view of loop 104 of IOL 100 is shown (along...) Figure 1 (The line BB in the middle) Figure 5 A cross-sectional view of the optics 102 and loop 104 of the IOL 100 is shown (along... Figure 1 (CC in the middle) Figure 6 Detailed cross-sectional views of the optics 102 and loop 104 of the IOL 100 are shown, as well as Figure 7 A detailed view of the gusset plate area 126 of the I0L 100 is shown.

[0020] IOL 100 can have an overall diameter 106 between 10mm and 15mm. In some embodiments, the overall diameter 106 can be approximately 13.5mm. Although Figure 1 The IOL 100 is depicted with two loops 104 (104a and 104b) having a defined total diameter of 106, but this disclosure contemplates that the IOL 100 may have any suitable number of loops.

[0021] Optical element 102 may include a front surface 108, a rear surface 110, an optical axis 112, and an optical element edge 114. The front and / or rear surfaces may include any suitable surface profile for correcting the patient's vision. For example, the front and / or rear surface 108 may be spherical, aspherical, torus, refractive, diffractive, or any suitable combination thereof. In other words, optical element 102 may be one or more of a spherical lens, an aspherical lens, a torus lens, a multifocal lens (refractive or diffractive), an extended depth-of-focus lens, or any other suitable type of lens.

[0022] The front surface 108 may have a front surface diameter 116 between 4.5 mm and 7.0 mm. In one specific embodiment, the front surface diameter 116 may be approximately 6 mm. Furthermore, the front surface 108 may include full-coverage optics, meaning that the optical portion of the front surface 108 extends to the optics edge 114. Alternatively, the front surface 108 may include multiple transition regions (not depicted) between the edge of the optical region of the front surface 108 and the optics edge 114.

[0023] The rear surface 110 may have a rear surface diameter 118 between 4.5 mm and 7.0 mm. In one specific embodiment, the rear surface diameter 118 may be approximately 6.15 mm (or may vary within a range including 6.15 mm depending on the lens refractive power). Furthermore, the rear surface 108 may include an optical portion 120 and a transition portion 122 located between the optical region 120 and the edge 114 of the optical device (e.g., ...). Figure 3(As best depicted). Alternatively, the rear surface 110 may include full-coverage optics, meaning that the optical portion of the rear surface 110 extends to the edge 114 of the optics.

[0024] In embodiments where the rear surface 108 includes an optical portion 120 and a transition portion 122, and the rear surface diameter 118 is approximately 6.15 mm, the optical portion 120 of the rear surface 110 may have a diameter of approximately 6 mm. The transition portion 122 may include one or more curved surfaces, one or more flat surfaces, or any suitable combination thereof. In some embodiments, the intersection of the transition portion 122 and the optical edge 114 may form an angle 124 of approximately 90 degrees.

[0025] The optical element edge 114 may extend between the front surface 108 and the rear surface 110 and may include one or more curved surfaces, one or more flat surfaces, or any suitable combination thereof. In one embodiment, the optical element edge 114 may include a continuously curved surface extending between the front surface 108 and the rear surface 110. In such an embodiment, the continuously curved surface may not include any tangents parallel to the optical axis 112, which can advantageously reduce the occurrence of positive glare phantoms, at least in part, due to edge glare.

[0026] Each loop 104 includes a gusset region 126, a bend region 128, and a distal region 130. The gusset region 126 may extend from the periphery of the optics 102 and may cross an angle 132 at the periphery of the optics 102. In some embodiments, the angle 132 may be greater than or equal to 50 degrees. In some other embodiments, the angle 132 may be greater than or equal to 60 degrees. In other embodiments, the angle 132 may be greater than or equal to 70 degrees. In one specific embodiment, the angle 132 may be approximately 70 degrees.

[0027] In some embodiments, the total thickness of the gusset plate region 126 can monotonically increase as the distance from the optical axis 112 increases (e.g., Figures 5 to 6 (As best depicted). In other words, at the connection point with the periphery of the optics 102, region 126 may have a minimum thickness, and said thickness may monotonically increase between the periphery of the optics 102 and the bend region 128. For example, at the periphery of the optics, the gusset region 126 may have a minimum thickness between 0.16 mm and 0.40 mm. As another example, at the periphery of the optics, the gusset region 126 may have a minimum thickness between 0.20 mm and 0.35 mm. As yet another example, at the periphery of the optics, the gusset region 126 may have a minimum thickness of approximately 0.25 mm (for IOL 100 with lower refractive power) and 0.35 mm (for IOL 100 with higher refractive power).

[0028] In an alternative embodiment, the total thickness of each gusset region 126 may increase monotonically only over a portion of the gusset region 126. In other words, the thickness of the gusset region 126 may increase monotonically within a first distance from the optical axis 112, and may have a constant thickness or a decreasing thickness (or a combination thereof) within a second distance from the optical axis 112.

[0029] The bend region 128 may include the portion of the loop 104 with the minimum width. For example, the width 134 of the bend region 128 may be between 0.40 mm and 0.65 mm. As another example, the width 134 of the bend region 128 may be approximately 0.50 mm. Because the bend region 128 includes the portion of the loop 104 with the minimum width, the bend region 128 can create a turning point that allows the loop 104 to bend while minimizing buckling and camber of the optics 102.

[0030] The distal region 130 may extend from the bend region 128 and may have a length 136 in the range of 6 mm to 7.5 mm. In some embodiments, the distal region 130 may have a length 136 in the range of 6.5 mm to 7 mm. In one specific embodiment, the distal region 130 may have a length 136 of approximately 6.8 mm.

[0031] In some embodiments, the width of the distal region 130 varies along its length 136. In one specific embodiment, the distal region 130 may have a maximum width 138 of approximately 0.90 mm and a minimum width 140 of approximately 0.65 mm. Furthermore, the width of the distal region 130 may vary between the rear surface and the front surface of the loop 104. For example, as... Figure 4 As shown, the rear surface of loop 105 can be wider than the front surface; in this case, the width discussed above refers to the width at the wider rear surface. Although both the front and rear surfaces of loop 104 are... Figure 4 While depicted as substantially flat, this disclosure contemplates that, in some embodiments, one or both of the front and rear surfaces of the loop 104 may include curvature. In such embodiments, the surface area of ​​the loop 104 that contacts the optics 102 or each other when folded by the IOL 100 for delivery can be reduced, thereby reducing the likelihood of the loop 104 sticking to the optics 102 or to each other after delivery. Therefore, deployment performance can be improved.

[0032] In some embodiments, the total thickness of each distal region 130 can monotonically decrease as the distance from the bend region 128 increases. In other words, the thickness of the distal region 130 of each loop 104 can monotonically decrease along its length 136. For example, the distal region 130 can have a maximum thickness between 0.33 mm and 0.57 mm near the bend region 128. As another example, the distal region 130 can have a maximum thickness between 0.37 mm and 0.53 mm near the bend region 128. As another example, the distal region 130 can have a maximum thickness of approximately 0.47 mm near the bend region 128. From the point of maximum thickness, the thickness of the distal region 130 decreases linearly with increasing distance from the optical axis 112 (thus the thickness decreases non-linearly along the length 136 of the distal region 130). As a specific example, the thickness of the distal region 130 can be reduced such that, in cross-section (see...), the thickness of the distal region 130 decreases... Figure 5 The front surface of the distal region 130 is tilted at an angle of approximately 3 degrees. Alternatively, from the point of maximum thickness, the thickness of the distal region 130 can decrease nonlinearly with increasing distance from the optical axis 112.

[0033] In an alternative embodiment, the total thickness of each distal region 130 may decrease monotonically only over a portion of the distal region 130. In other words, the thickness of the distal region 130 may decrease monotonically within a first distance from the bend region 128; and may have a constant thickness or an increasing thickness (or a combination thereof) within a second distance from the bend region 128.

[0034] The above-described configuration of loop 104 can provide one or more technical advantages. For example, the above-described configuration of loop 104 can improve the uniformity of tactile force distribution, thereby reducing pleats (marks) in the pouch while maintaining axial and rotational stability for most pouch sizes. More specifically, by providing a larger (greater than 50 degrees in some embodiments) contact angle compared to current one-piece IOLs (whose angle range can be between 40-45 degrees), the above-described configuration of loop 104 can improve the uniformity of tactile force distribution. Furthermore, the thickness variation in different regions of loop 104 can provide the required stability while minimizing volume, thereby helping to reduce cut size.

[0035] In some embodiments, all or part of the loop 104 may have a textured surface. A textured loop surface can reduce the likelihood of the loop 104 sticking to the optics 102 during delivery. Furthermore, the texture on the edge 114 of the optics can mitigate or minimize edge glare by diffusing unwanted light generated by reflection or transmission from the edge, thereby reducing the occurrence of positive glare phantoms.

[0036] Various techniques and materials can be used to manufacture the IOL 100 described above. For example, the optics 102 of the IOL 100 can be formed from various biocompatible polymer materials. Some suitable biocompatible materials include, but are not limited to, soft acrylic polymers, hydrogels, polymethacrylates, or polysulfones, or polystyrene-containing copolymers, or other biocompatible materials. For example, in one embodiment, the optics 102 can be formed from a soft acrylic hydrophobic copolymer, such as that described in U.S. Patent Nos. 5,290,892; 5,693,095; 8,449,610; or 8,969,429. The loop 104 of the IOL 100 can also be formed from suitable biocompatible materials, such as those discussed above. While in some cases the optics 102 and loop 104 of the IOL can be manufactured as a single unit, in other cases they can be formed separately or joined together using techniques known in this art.

[0037] It will be appreciated that the various features and functions disclosed above, and others, or alternatives thereof, can be combined as desired into many other different systems or applications. It will also be appreciated that various alternatives, modifications, variations, or improvements not currently foreseen or anticipated can subsequently be made by those skilled in the art, and such alternatives, variations, and improvements are also intended to be covered by the appended claims.

Claims

1. An ophthalmic lens, comprising: An optical device including a front surface, a rear surface, and an optical device edge extending between the front and rear surfaces, the optical device having an optical axis; as well as A plurality of loops extend from the periphery of the optical device, and each of the plurality of loops includes a front loop surface and a rear loop surface, wherein for at least a portion of the loop, the width of the rear loop surface is greater than the width of the front loop surface. The loop also includes a gusset region, a distal region, and a bend region connecting the gusset region to the distal region, wherein: The gusset plate region of the loop extends from the periphery of the optical device and crosses a portion of the periphery of the optical device; In at least a portion of the gusset plate region, the thickness of the gusset plate region of the loop monotonically increases with increasing distance from the periphery of the optical device; In at least a portion of the distal region, the thickness of the distal region of the loop decreases monotonically with increasing distance from the bend region.

2. The ophthalmic lens of claim 1, wherein the bend region of the loop includes the region of the loop having a minimum loop width.

3. The ophthalmic lens of claim 1, wherein at least a portion of the surface of the loop is textured.

4. The ophthalmic lens of claim 1, wherein one or both of the anterior loop surface and the posterior loop surface include curvature.

5. The ophthalmic lens of claim 1, wherein the thickness of the distal region of the loop decreases linearly with increasing distance from the optical axis.

6. The ophthalmic lens of claim 5, wherein the thickness of the distal region of the loop decreases non-linearly with increasing distance from the bend region.

7. The ophthalmic lens of claim 1, wherein the distal region of the loop includes a portion having a constant thickness or a thickness that increases with distance from the bend region.

8. The ophthalmic lens of claim 1, wherein the thickness of the gusset region of the loop increases linearly with increasing distance from the periphery of the optics.

9. The ophthalmic lens of claim 1, wherein the thickness of the gusset region of the loop increases non-linearly with increasing distance from the periphery of the optics.

10. The ophthalmic lens of claim 1, wherein the gusset region of the loop includes a portion having a constant thickness or a thickness that decreases with increasing distance from the bend region.

11. An ophthalmic lens, comprising An optical device, the optical device including a front surface, a rear surface, and an optical device edge extending between the front surface and the rear surface, the optical device having an optical axis; and A plurality of loops extending from the periphery of the optical device, each of the plurality of loops including a front loop surface and a rear loop surface, wherein for at least a portion of the loop, the width of the rear loop surface is greater than the width of the front loop surface, each of the plurality of loops including a gusset plate region, a distal region, and a bend region connecting the gusset plate region to the distal region, wherein: The gusset plate region of the loop extends from the periphery of the optical device and crosses a portion of the periphery of the optical device; In at least a portion of the gusset plate region, the thickness of the gusset plate region of the loop monotonically increases with increasing distance from the periphery of the optical device; as well as In at least a portion of the distal region, the thickness of the distal region of the loop decreases linearly with increasing distance from the optical axis.

12. The ophthalmic lens of claim 11, wherein the bend region of the loop includes the region of the loop having a minimum loop width.

13. The ophthalmic lens of claim 11, wherein at least a portion of the surface of the loop is textured.

14. The ophthalmic lens of claim 11, wherein the thickness of the gusset region of the loop increases linearly with increasing distance from the periphery of the optics.

15. The ophthalmic lens of claim 11, wherein the thickness of the gusset region of the loop increases non-linearly with increasing distance from the periphery of the optics.

16. The ophthalmic lens of claim 11, wherein the gusset region of the loop includes a portion having a constant thickness or a thickness that decreases with increasing distance from the bend region.

17. An ophthalmic lens, comprising An optical device, the optical device including a front surface, a rear surface, and an optical device edge extending between the front surface and the rear surface, the optical device having an optical axis; and A plurality of loops extending from the periphery of the optical device, each of the plurality of loops including a front loop surface and a rear loop surface, wherein for at least a portion of the loop, the width of the rear loop surface is greater than the width of the front loop surface, each of the plurality of loops including a gusset plate region, a distal region, and a bend region connecting the gusset plate region to the distal region, wherein: The gusset plate region of the loop extends from the periphery of the optical device and crosses a portion of the periphery of the optical device; In at least a portion of the gusset region, the thickness of the gusset region of the loop increases linearly with increasing distance from the periphery of the optical device; and In at least a portion of the distal region, the thickness of the distal region of the loop decreases monotonically with increasing distance from the bend region.

18. The ophthalmic lens of claim 17, wherein the thickness of the distal region of the loop decreases linearly with increasing distance from the optical axis.

19. The ophthalmic lens of claim 18, wherein the thickness of the distal region of the loop decreases non-linearly with increasing distance from the bend region.

20. The ophthalmic lens of claim 17, wherein the distal region of the loop includes a portion having a constant thickness or a thickness that increases with distance from the bend region.

21. An ophthalmic lens, comprising: An optical device including a front surface, a rear surface, and an optical device edge extending between the front surface and the rear surface, the optical device having an optical axis; as well as A plurality of loops extending from the periphery of the optical device at a gusset plate region, each of the plurality of loops including a front loop surface and a rear loop surface, wherein for at least a portion of the loop, the width of the rear loop surface is greater than the width of the front loop surface, each of the plurality of loops including a gusset plate region, a distal region, and a bend region connecting the gusset plate region to the distal region, wherein: Each of the plurality of loops has a gusset plate region spanning at least seventy degrees across the periphery of the optical device, and on at least a portion of the gusset plate region, the thickness of the gusset plate region of the loop monotonically increases with increasing distance from the periphery of the optical device. The thickness of the distal region of each of the plurality of loops decreases monotonically across the entire distal region as the distance from the bend region increases, wherein the distal region of each of the plurality of loops includes the end region of each loop. as well as At least a portion of the surface of each of the plurality of loops is textured.

22. The ophthalmic lens of claim 21, wherein the edge of the optics defines an edge surface having a single radius of curvature, and the edge surface has no tangents parallel to the optical axis.

23. The ophthalmic lens of claim 21, wherein the width of the anterior loop surface and the width of the posterior loop surface are defined in a direction perpendicular to the optical axis.

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