双(2-(二取代基膦基)芳基)锗烷配体及其制备方法
By preparing bis(2-(disubstituted phosphinyl)aryl)germanium ligands, the problems of poor versatility and catalytic activity of existing ligands in organic reactions were solved. Effective coordination with metal atoms and efficient catalysis were achieved, filling the gap in organogenergic ligands and possessing potential special catalytic value.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- UNIV OF SCI & TECH OF CHINA
- Filing Date
- 2022-11-24
- Publication Date
- 2026-07-17
AI Technical Summary
Existing P-Si-P or P-GeHR-P ligands have poor versatility in organic reactions, are difficult to effectively coordinate to metal atoms, and have large steric hindrance, resulting in poor coordination catalytic activity.
A bis(2-(disubstituted phosphino)aryl)germanane ligand is provided, which is generated by reacting 1-bromo-2-iodoarylbenzene with disubstituted phosphine hydrogen in the presence of palladium catalyst and base to produce (2-bromoaryl)disubstituted phosphine, then reacting with lithium reagent and germanium tetrachloride, and finally reacting with lithium aluminum hydride to generate bis(2-(disubstituted phosphino)aryl)germanane ligand, forming a germanium-ion-bridged 2-(disubstituted phosphino)aryl pincer ligand that can coordinate with metal atoms to form Ge-M active metal species.
The versatility of ligands and their coordination catalytic activity in organic reactions have been improved. The resulting Ge-M active metal species play an important role in the field of metal catalysis and have the advantages of stable properties, multiple modifiable sites, readily available raw materials, and simple synthesis methods.
Smart Images
Figure CN115894550B_ABST