A low remanence halbach array magnetic force attraction separation device

Abstract

The application provides a low remanence halbach array magnetic force adsorption separation device, which comprises a magnetic ring, the magnetic ring comprises a left half ring and a right half ring which jointly form a circular adsorption separation area, a plurality of magnets around the adsorption separation area are arranged in the left half ring and the right half ring, and a magnetic force line extension line of one magnet with an angle of 45 degrees with a line of abutment of the left half ring and the right half ring passes through the center of the adsorption separation area. Compared with the prior art, the structure of the magnetic ring is improved, so that when the magnetic ring is closed, a magnetic field with high intensity and good uniformity is formed in the adsorption separation area, and the adsorption separation efficiency is high. When the magnetic ring is opened, the integrity of the two-side magnetic pole arrangement is broken, the remanence between the left half ring and the right half ring is reduced, and the working efficiency of the next cycle separation is ensured.

Description

Technical Field

[0001] This invention belongs to the field of magnetic field adsorption and separation technology, and particularly relates to a low remanence Halbach array magnetic adsorption and separation device. Background Technology

[0002] With the rapid development of industries such as bioengineering and life sciences, magnetic field adsorption separation technology has been widely used in the field of biotechnology due to its advantages such as strong processing capacity, simple and reliable equipment, cleanliness, and energy saving.

[0003] In existing technologies, in order to obtain a high-efficiency and rapid adsorption rate, optimization designs are carried out by selecting high-performance magnets, increasing the magnet volume, and reducing the gap between the magnet and the adsorbed object.

[0004] The shortcomings of existing technologies lie in the limited optimization potential of the aforementioned methods, resulting in minimal improvement in adsorption speed. Furthermore, existing magnetic field adsorption separation technologies suffer from significant residual magnetism in the non-separated medium (with the magnetic ring open), which negatively impacts the efficiency of subsequent separation cycles. Summary of the Invention

[0005] (a) Technical problems to be solved Based on this, the present invention provides a low remanence Halbach array magnetic adsorption separation device to solve the technical problem that existing magnetic adsorption separation devices have large remanence in the non-separation state.

[0006] (II) Technical Solution To solve the above-mentioned technical problems, the present invention proposes a low remanence Halbach array magnetic adsorption and separation device, including a magnetic ring. The magnetic ring includes a left half ring and a right half ring that together form a circular adsorption and separation region. The left half ring and the right half ring include a plurality of magnets surrounding the adsorption and separation region. The magnetic field line extension of a magnet with an angle of 45° with the contact line of the left half ring and the right half ring passes through the center of the adsorption and separation region.

[0007] Preferably, a plurality of the magnets are uniformly arranged around the adsorption separation region.

[0008] Preferably, n dividing lines passing through the center of the adsorption separation region but not through the bonding line between the left and right halves of the ring divide the magnetic ring into 2n regions, where n≥2. Magnets are symmetrically arranged on both sides of each dividing line. In the 2n regions, at least one region has a portion of the magnets located in the left half of the ring and the remaining portion of the magnets located in the right half of the ring.

[0009] Preferably, n=2; the angle between the bonding line of the left and right half-rings and one of the dividing lines is A, where A=45°.

[0010] Preferably, each of the magnets rotates in the same direction relative to the preceding magnet adjacent to it, and the rotation angle of each of the magnets relative to the preceding magnet adjacent to it is 30°.

[0011] Preferably, the left half ring includes a left half support and a left half yoke arranged around the left half support, and part of the magnet is disposed between the left half support and the left half yoke.

[0012] Preferably, the right half ring includes a right half support and a right half yoke arranged around the right half support, and the remaining part of the magnet is arranged between the right half support and the right half yoke.

[0013] Preferably, the left half support and the right half support together form a ring, and the left half magnetic yoke and the right half magnetic yoke together form a ring.

[0014] Preferably, both the left and right half of the magnetic yoke are made of stainless steel.

[0015] Preferably, the low remanent magnetization Halbach array magnetic adsorption separation device further includes a reactor for loading the drug solution and magnetic beads, with the magnetic ring arranged around the reactor.

[0016] (III) Beneficial Effects Compared with the prior art, the low remanence Halbach array magnetic adsorption separation device of the present invention has the following advantages: This invention improves the structure of the magnetic ring, ensuring that a high-intensity and highly uniform magnetic field is formed in the adsorption and separation region when the magnetic ring is closed, resulting in high adsorption and separation efficiency. When the magnetic ring is open, it breaks the integrity of the magnetic pole arrangement on both sides, reducing the residual magnetism between the left and right halves of the ring and ensuring the working efficiency of the next separation cycle. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of the present invention. Figure 1 (Closed state).

[0019] Figure 2 This is a schematic diagram of the overall structure of the present invention. Figure 2 (Open).

[0020] Figure 3 This is a magnetic field diagram of the magnetic ring in the closed state according to the present invention.

[0021] Figure 4 This is a magnetic field diagram of the magnetic ring of the present invention in the open state (non-working state).

[0022] Figure 5 This is a magnetic field diagram of a symmetrical magnetic ring in a closed state.

[0023] Figure 6 This is a magnetic field diagram of a symmetrical magnetic ring in an open state (non-working state).

[0024] Explanation of reference numerals in the attached figures: 1. Magnetic ring, 2. Adsorption separation region, 3. Left half ring, 4. Right half ring, 5. Magnet, 6. Dividing line, 7. Left half support, 8. Left half yoke, 9. Right half support, 10. Right half yoke. Detailed Implementation

[0025] To make the above-mentioned objects, features, and advantages of the present invention more apparent and understandable, specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of the present invention. However, the present invention can be practiced in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0026] The following is in conjunction with the appendix Figure 1-6 The low remanence Halbach array magnetic adsorption separation device of the present invention will be further described.

[0027] Please refer to this carefully. Figure 1-2 The present invention discloses a low remanence Halbach array magnetic adsorption separation device, including a magnetic ring 1. The magnetic ring 1 includes a left half ring 3 and a right half ring 4 that together form a circular adsorption separation region 2. The left half ring 3 and the right half ring 4 include a plurality of magnets 5 surrounding the adsorption separation region 2. The magnetic field line extension of a magnet 5 with an angle of 45° with the contact line of the left half ring 3 and the right half ring 4 passes through the center of the adsorption separation region 2.

[0028] The specific explanation of "the extension line of the magnetic field of a magnet 5, which has an angle of 45° with the line of contact between the left half ring 3 and the right half ring 4, passes through the center of the adsorption separation region 2" in the above text is as follows: Let the line of contact between the left half ring 3 and the right half ring 4 be L1. There is a magnet in the magnetic ring 1. The extension line of the magnetic field of this magnet passes through the center of the adsorption separation region 2, and the angle between the extension line of the magnetic field of this magnet 5 and L1 is 45°.

[0029] The magnetic ring 1 of the present invention will be compared with the magnetic ring of the existing symmetrical structure below, in detail as follows: Please refer to... Figure 5The magnetic ring shown in the diagram has a symmetrical structure with two magnetic poles evenly distributed on both sides, as shown in the diagram. Figure 6 After the magnetic ring is opened, the magnetic lines of force spread more severely towards the middle of the left and right halves of the ring (the middle circle area).

[0030] Please refer to Figure 3-4 In the embodiment of the present invention, the magnetic ring 1, relative to the symmetrical magnetic ring, rotates the magnet 5 around the circle by 45°. One pole of the magnets 5 on both sides is located at the central axis, and the other two poles are divided into two poles. The magnetic lines of force are concentrated at the location of the magnets 5 on both sides, and the spread to the middle position (middle circle area) of the left half ring 3 and the right half ring 4 is significantly reduced.

[0031] As can be seen, in this embodiment, the magnetic ring 1 with this structure can ensure that when the magnetic ring 1 is closed (see...). Figure 3 A high-intensity and highly uniform magnetic field is formed in the adsorption and separation region 2, resulting in high adsorption and separation efficiency. When the magnetic ring 1 is open (see...), a high-intensity and highly uniform magnetic field is formed in the adsorption and separation region 2, resulting in high adsorption and separation efficiency. Figure 4 This can disrupt the integrity of the magnetic pole arrangement on both sides, reduce the residual magnetism between the left half-ring 3 and the right half-ring 4, and ensure the working efficiency of the separation in the next cycle. It should be noted that, in this invention, "residual magnetism" refers to the magnetic field located in the adsorption separation region 2 when the left half-ring 3 and the right half-ring 4 are open.

[0032] According to a specific embodiment of the present invention, a plurality of magnets 5 are uniformly arranged around the adsorption separation region 2.

[0033] In this embodiment, this structure helps to further improve the uniformity of the magnetic field in the adsorption separation region 2 when the magnetic ring 1 is closed.

[0034] According to a specific embodiment of the present invention, n dividing lines 6 passing through the center of the adsorption separation region 2 but not passing through the bonding line of the left half ring 3 and the right half ring 4 divide the magnetic ring 1 into 2n regions, where n≥2. Magnets 5 are symmetrically arranged on both sides of each dividing line 6. In the 2n regions, there is at least one region where some magnets 5 are located in the left half ring 3 and the remaining magnets 5 are located in the right half ring 4.

[0035] In this embodiment, "at least one region exists where a portion of the magnet 5 is located in the left half-ring 3 and the remaining portion of the magnet 5 is located in the right half-ring 4" means that there exists at least one such region, characterized in that a portion of the magnet 5 is located in the left half-ring 3 and the remaining portion of the magnet 5 is located in the right half-ring 4. In this embodiment, the line of contact between the left half-ring 3 and the right half-ring 4 is a straight line passing through the center of the adsorption separation region 2, that is, the central angle corresponding to the left half-ring 3 is 180°, and the central angle corresponding to the right half-ring 4 is 180°. All magnets 5 are divided into 2n regions by at least n dividing lines 6, and the central angle corresponding to each region is (360 / 2n)°.

[0036] With this structure, when the magnetic ring 1 is opened, the left half ring 3 or the right half ring 4 includes at least one complete region and two incomplete regions. This structure can effectively reduce the residual magnetism in the separation region and improve the working efficiency of magnetic separation in the next cycle.

[0037] According to a specific embodiment of the present invention, n=2; the angle between the bonding line and one dividing line 6 is A, where A=45°. In this embodiment, the two dividing lines 6 divide the magnetic ring 1 into four equal regions, which is the structure with the fewest number of regions. Its structure is also relatively simple and easy to manufacture.

[0038] According to a specific embodiment of the present invention, the rotation angle of any magnet 5 relative to its adjacent preceding magnet 5 is the same and not equal to zero, and the rotation direction of any magnet 5 relative to its adjacent preceding magnet 5 is the same.

[0039] More specifically, any magnet 5 rotates in the same direction relative to its adjacent preceding magnet 5, and the rotation angle of any magnet 5 relative to its adjacent preceding magnet 5 is 30°.

[0040] In this embodiment, this structure is used to form a Halbach array magnet 5 structure, which can generate a strong magnetic field with a small number of magnets 5, thereby increasing the magnetic field strength in the adsorption separation region 2 when the magnetic ring 1 is closed, which is beneficial to further improve the adsorption separation efficiency.

[0041] In this embodiment, the rotation angle of any magnet 5 relative to the preceding magnet 5 is related to the total number of magnets 5, and it is also necessary to satisfy the requirement that "the extension line of the magnetic field of a magnet 5 with an angle of 45° with the line of contact between the left half ring 3 and the right half ring 4 passes through the center of the adsorption separation region 2".

[0042] According to a specific embodiment of the present invention, the left half ring 3 includes a left half support 7 and a left half magnetic yoke 8 arranged around the left half support 7, and a portion of the magnet 5 is disposed between the left half support 7 and the left half magnetic yoke 8.

[0043] More specifically, the right half-ring 4 includes a right half-support 9 and a right half-yoke 10 surrounding the right half-support 9, with the remaining magnet 5 positioned between the right half-support 9 and the right half-yoke 10. The left half-support 7 and the right half-support 9 together form a ring, as do the left half-yoke 8 and the right half-yoke 10. Both the left half-yoke 8 and the right half-yoke 10 are made of stainless steel. The low remanent magnetization Halbach array magnetic adsorption separation device also includes a reactor for holding the drug solution and magnetic beads, with the magnetic ring 1 surrounding the reactor. The magnetic ring 1 is used for magnetic adsorption separation of the drug solution contained in the reactor.

Claims

1. A low-remanence Halbach array magnetic adsorption separation device, characterized in that, Includes a magnetic ring (1), the magnetic ring (1) includes a left half ring (3) and a right half ring (4) that together form a circular adsorption separation region (2), the left half ring (3) and the right half ring (4) include a plurality of magnets (5) surrounding the adsorption separation region (2), and the magnetic field line extension of a magnet with an angle of 45° with the contact line of the left half ring (3) and the right half ring (4) passes through the center of the adsorption separation region (2); The magnetic ring (1) is divided into 2n regions by n dividing lines (6) passing through the center of the adsorption separation region (2) and not passing through the bonding line of the left half ring (3) and the right half ring (4), where n=2. The magnets (5) on both sides of each dividing line (6) are symmetrically arranged. In the 2n regions, there is at least one region where some magnets (5) are located in the left half ring (3) and the remaining magnets are located in the right half ring (4). The angle between the fitting line of the left half ring (3) and the right half ring (4) and a dividing line (6) is A, where A = 45°; multiple magnets (5) are evenly arranged around the adsorption separation area (2); and any one of the magnets (5) has the same rotation direction relative to the preceding magnet (5) adjacent to it, and the rotation angle of any one of the magnets (5) relative to the preceding magnet (5) adjacent to it is 30°.

2. The low remanence Halbach array magnetic adsorption separation device according to claim 1, characterized in that, The left half ring (3) includes a left half support (7) and a left half yoke (8) arranged around the left half support (7), with part of the magnet (5) disposed between the left half support (7) and the left half yoke (8).

3. The low remanence Halbach array magnetic adsorption separation device according to claim 2, characterized in that, The right half ring (4) includes a right half support (9) and a right half yoke (10) arranged around the right half support (9), with the remaining part of the magnet (5) located between the right half support (9) and the right half yoke (10).

4. The low remanence Halbach array magnetic adsorption separation device according to claim 3, characterized in that, The left half support (7) and the right half support (9) together form a ring, and the left half magnetic yoke (8) and the right half magnetic yoke (10) together form a ring.

5. The low remanence Halbach array magnetic adsorption separation device according to claim 4, characterized in that, Both the left half yoke (8) and the right half yoke (10) are made of stainless steel.

6. The low remanence Halbach array magnetic adsorption separation device according to claim 5, characterized in that, The low remanent magnetization Halbach array magnetic adsorption separation device also includes a reactor for loading the drug solution and magnetic beads, and the magnetic ring (1) is arranged around the reactor.

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