Quartz reaction cell and method of processing thereof

Abstract

The application discloses a quartz reaction cell processing method, which comprises the following steps: step one, decomposition: according to a reaction cell structure model, the reaction cell is decomposed into multiple parts convenient for cutting processing; step two, cutting: cutting the part embryo of each part obtained by using a wire cutting mode; step three, grinding: grinding the part embryo obtained by cutting; step four, polishing: polishing all surfaces as inner surfaces of reaction cavities in each part embryo, and polishing all contact surfaces in the part embryo splicing; step five, splicing, drilling and annealing: splicing all parts into a reaction cell product by bonding, processing a through hole on the reaction cell product, and performing annealing treatment on the reaction cell product; and step six, cleaning: drying the reaction cell product after cleaning. The application further discloses a quartz reaction cell obtained by using the method. The quartz reaction cell and the processing method thereof can realize industrialized production and manufacturing of the reaction cell by using quartz material.

Description

Technical Field

[0001] This invention belongs to the field of in vitro diagnostic technology, specifically a quartz reaction cell and its processing method. Background Technology

[0002] Existing reaction tanks are generally made of transparent resin. Transparent resin has good light transmittance, and its hardness and processability meet the processing requirements of reaction tanks. Therefore, in the existing technology, using transparent resin, reaction tanks can be easily made into various shapes and structures. In addition, transparent resin has the advantage of being not easily broken, and even reaction tanks of different shapes and structures can be easily installed and fixed using various methods.

[0003] However, as the requirements for blood cell detection become increasingly stringent, the light transmittance of transparent resin is gradually failing to meet the demands of high-end blood cell analyzers. Quartz, with its excellent optical properties, hydrophilicity, and resistance to temperature shock, is an ideal material for fabricating reaction cells for immune responses. However, quartz's high hardness and melting point make its molding and processing extremely difficult. Furthermore, the small size and thin walls of the reaction cells, combined with quartz's typical brittleness, make it highly susceptible to breakage during reaction cell fabrication. Therefore, although quartz is an ideal material for manufacturing reaction cells, the difficulty in processing and shaping it hinders the mass production of reaction cells made from quartz. Summary of the Invention

[0004] In view of this, the purpose of the present invention is to provide a quartz reaction cell and its processing method, which enables the industrial production of the reaction cell using quartz material.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] This invention first proposes a method for processing a quartz reaction cell, comprising the following steps:

[0007] Step 1: Decomposition: Based on the structural model of the reaction tank, decompose the reaction tank into multiple parts that are easy to cut and process;

[0008] Step 2, Cutting: Use wire cutting to cut the quartz material to obtain the blanks of each part;

[0009] Step 3, Grinding: Grinding and cutting to obtain the part blank;

[0010] Step 4, Polishing: Polish all surfaces in each part blank that serve as the inner surface of the reaction chamber, and polish all contact surfaces during the assembly of the part blanks;

[0011] Step 5: Assembly, Drilling, and Annealing: Assemble all parts into a reaction tank product by bonding, machine through holes in the reaction tank product, and anneal the reaction tank product.

[0012] Step 6: Cleaning: After cleaning the product in the reaction tank, dry it.

[0013] Furthermore, in step one, the method for decomposing the reaction tank is as follows:

[0014] 11) The reaction tank is decomposed into a tank body and a tank bottom, wherein the decomposition surface of the tank body and the tank bottom is the interface between the cylindrical section and the constriction section of the reaction chamber.

[0015] 12) Decompose the parts corresponding to the two light-transmitting surfaces of the pool body and the reaction chamber into two pool body light-transmitting surface parts, and decompose the parts between the two pool body light-transmitting surface parts into inner curved surface parts of the pool body; decompose the protruding parts on the inner curved surface parts of the pool body into pool body patch parts.

[0016] Furthermore, in step two, wire cutting is used to obtain part blanks for the pool bottom, pool body patch parts, two pool body light-transmitting surface parts, and two pool body inner curved surface parts.

[0017] Furthermore, in step four, the polishing method is as follows:

[0018] 31) Polishing the inner surface of the reaction chamber: The inner surfaces of the curved parts inside the two pools, the inner surfaces of the light-transmitting parts inside the two pools, and the upper surface of the bottom of the pools serving as the closing section of the reaction chamber are polished using an oxyhydrogen flame polisher; then the inner surfaces of the light-transmitting parts inside the two pools are polished using a ring mill, so that the roughness of the inner surfaces of the light-transmitting parts inside the two pools reaches the nanometer level.

[0019] 32) Polishing contact surfaces: The contact surfaces of the pool bottom, pool body patch parts, two pool body light-transmitting surface parts, and two pool body inner curved surface parts are polished using a ring mill to achieve a roughness of nanometer level for all contact surfaces.

[0020] Furthermore, the polishing temperature of the oxyhydrogen flame polishing machine is 1900-2000℃, and the polishing time is 2-4 hours.

[0021] Furthermore, step five includes the following steps:

[0022] 51) Bond the two inner curved surface parts and the two inner light-transmitting surface parts of the pool in sequence to obtain the first assembly, and then bond the first assembly to the bottom of the pool to obtain the second assembly. Set the second assembly to stand for a set time.

[0023] 52) Anneal the second assembly;

[0024] 53) Use a ring mill to polish the outer surface of the bonding pool patch parts of the second assembly to a nanoscale roughness.

[0025] 54) After bonding the pool body patch parts to the corresponding outer surface of the second assembly, the third assembly is obtained. The third assembly is then left to stand for a set time.

[0026] 55) Anneal the third assembly;

[0027] 56) Drilling is performed at the designated position of the third assembly to obtain the reaction tank product;

[0028] 57) Anneal the product from the reaction tank.

[0029] Furthermore, the method for annealing the second assembly, the third assembly, and the product from the reaction tank is as follows: the temperature is uniformly increased from 200°C to 1200±100°C in the annealing furnace over 14 hours, then held for 4 hours, and then cooled to 200°C over another 14 hours before being removed from the furnace and cooled to room temperature.

[0030] The present invention also proposes a quartz reaction cell, which is processed using the quartz reaction cell processing method described above.

[0031] Furthermore, it includes a reaction tank body made of quartz material, wherein the reaction tank body has a reaction chamber with an opening at the top, and the bottom of the reaction chamber has a drain port;

[0032] The reaction chamber includes a cylindrical section at the top and a tapering section at the bottom; the cylindrical section includes two opposing inner curved surfaces and two opposing light-transmitting surfaces, with a transition surface between adjacent inner curved surfaces and light-transmitting surfaces, the transition surface making the corresponding inner curved surface and light-transmitting surface transition smoothly; the tapering section gradually narrows the bottom surface of the reaction chamber to the drain port along the direction from top to bottom;

[0033] The outer side wall of the reaction tank body corresponding to the inner curved surface is provided with a protrusion, and the protrusion is provided with a through hole that communicates with the reaction chamber;

[0034] The sidewalls of the reaction tank body corresponding to the light-transmitting surface are made of light-transmitting quartz material.

[0035] Furthermore, the protrusion is provided in two parts, namely an upper protrusion and a lower protrusion. The upper protrusion is located above the lower protrusion, and the upper protrusion and the lower protrusion are respectively provided with through holes that communicate with the reaction chamber.

[0036] The beneficial effects of this invention are as follows:

[0037] The quartz reaction cell processing method of the present invention first decomposes the reaction cell into multiple parts that are easy to cut and process, based on the structural model of the reaction cell. Then, wire cutting is used to cut the quartz material to obtain part blanks for each part. Next, specific surfaces of each part blank are sequentially ground and polished to ensure that all surfaces serving as the inner surface of the reaction chamber and all contact surfaces of the parts during assembly meet the set roughness requirements, thus satisfying the usage and assembly accuracy requirements of the reaction chamber. Finally, the parts are bonded together to form the reaction cell product. Through holes are drilled in the reaction cell product, followed by annealing. After cleaning and drying, the quartz reaction cell is obtained, ensuring bonding accuracy and optical performance. In summary, the quartz reaction cell processing method of the present invention enables the industrial production of reaction cells using quartz materials.

[0038] Other technical effects of the present invention are as follows:

[0039] In step five, the two inner curved surface parts and the two inner transparent surface parts of the two pools are first bonded to obtain the first assembly. Then, the first assembly is bonded to the bottom of the pool to obtain the second assembly. The second assembly is first annealed to ensure the bonding strength of the second assembly, which serves as the main structure of the reaction pool. Then, the outer surface of the pool patch parts to be bonded on the second assembly is polished to a nanometer roughness. The pool patch parts are then bonded to the corresponding outer surface of the second assembly to obtain the third assembly. The third assembly is then annealed to ensure the bonding strength between the pool patch parts and the second assembly. After that, through holes are drilled in the third assembly. Finally, the obtained reaction pool product is annealed to further strengthen the bonding strength between the various parts. In particular, during the annealing process, the temperature of the annealing furnace is uniformly raised from 200℃ to 1200±100℃ for 14 hours, then held for 4 hours, and finally cooled to 200℃ for another 14 hours. This temperature curve can reduce temperature shock and ensure the bonding strength between the parts. Attached Figure Description

[0040] To make the objectives, technical solutions, and beneficial effects of this invention clearer, the following figures are provided for illustration:

[0041] Figure 1 This is a schematic diagram of the structure of an embodiment of the quartz reaction cell of the present invention;

[0042] Figure 2 This is a top view of the quartz reaction cell in this embodiment;

[0043] Figure 3 This is an exploded view of the quartz reaction cell in this embodiment;

[0044] Figure 4 This is an exploded view of the individual components after the reaction tank of this embodiment has been disassembled;

[0045] Figure 5 This is a schematic diagram showing the decomposed interface between the light-transmitting surface parts and the curved surface parts inside the pool.

[0046] Figure 6 This is a schematic diagram of the structure of the second assembly;

[0047] Figure 7 This is a schematic diagram of the third assembly.

[0048] Explanation of reference numerals in the attached figures:

[0049] 10-Reaction tank body; 11-Reaction chamber; 12-Drain outlet; 13-Cylindrical section; 13a-Inner curved surface; 13b-Transparent surface; 13c-Transition curved surface; 14-Constriction section; 15-Through hole; 16-Upper protrusion; 17-Lower protrusion;

[0050] 20 - Pool body; 21 - Light-transmitting surface parts of the pool body; 22 - Curved surface parts inside the pool body; 23 - Upper pool body patch parts; 24 - Lower pool body patch parts;

[0051] 30 - Bottom of the pool. Detailed Implementation

[0052] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments described are not intended to limit the present invention.

[0053] like Figure 1-2As shown, the quartz reaction cell of this embodiment includes a reaction cell body 10 made of quartz material. The reaction cell body 10 has a reaction chamber 11 with an open upper end, and a drain outlet 12 at the bottom of the reaction chamber 11. The reaction chamber 11 includes a cylindrical section 13 at the top and a tapering section 14 at the bottom. The cylindrical section 13 includes two opposing inner curved surfaces 13a and two opposing light-transmitting surfaces 13b. A transition surface 13c is provided between adjacent inner curved surfaces 13a and light-transmitting surfaces 13b, allowing for a smooth transition between the corresponding inner curved surfaces 13a and light-transmitting surfaces 13b. In this embodiment, the light-transmitting surface 13b is planar. The sidewalls of the reaction cell body 10 corresponding to the light-transmitting surface 13b are made of light-transmitting quartz material to ensure the optical performance of the light-transmitting surface of the reaction chamber. In this embodiment, the tapering section 14 gradually narrows from top to bottom to the drain outlet 12, meaning the tapering section 14 forms the bottom of the reaction chamber 11. In this embodiment, a protrusion is provided on the outer wall of the reaction tank body 10 corresponding to the inner curved surface 13a, and a through hole 15 communicating with the reaction chamber is provided on the protrusion. In this embodiment, there are two protrusions, namely an upper protrusion 16 and a lower protrusion 17. The upper protrusion 16 is located above the lower protrusion 17, and the upper protrusion 16 and the lower protrusion 17 are respectively provided with through holes 15 communicating with the reaction chamber 11. The through holes 15 are used to introduce reagents or cleaning solutions into the reaction chamber 11. However, since the sidewall of the reaction chamber 11 is thin and the quartz material is brittle, if a hole is directly drilled in the sidewall of the reaction chamber 11, it is very likely that the sidewall of the reaction chamber 11 will crack. In this embodiment, by providing a protrusion on the outer wall of the reaction tank body 10 that requires an opening, on the one hand, the local thickness of the sidewall of the reaction chamber 11 can be increased to prevent cracking during drilling. On the other hand, the longer through hole 15 can also facilitate the installation of reagent tubes.

[0054] The following describes the specific implementation method of the quartz reaction cell processing method in this embodiment, in conjunction with the quartz reaction cell described above.

[0055] The quartz reaction cell processing method of this embodiment includes the following steps:

[0056] Step 1: Decomposition: Based on the reaction tank structural model, decompose the reaction tank into multiple parts that are easy to cut and process. Specifically, such as... Figure 3-4 As shown, the method for decomposing the reaction tank in this embodiment is as follows:

[0057] 11) The reaction tank is decomposed into tank body 20 and tank bottom 30. The decomposition surface of tank body 20 and tank bottom 30 is the interface between cylindrical section 13 and constriction section 14 of reaction chamber 11.

[0058] 12) Decompose the portions corresponding to the two light-transmitting surfaces 13b of the pool body 20 and the reaction chamber 11 into two pool body light-transmitting surface parts 21, and decompose the portion between the two pool body light-transmitting surface parts 21 into a curved surface part 22 inside the pool body; decompose the protruding portions on the curved surface part 22 inside the pool body into pool body patch parts. Specifically, such as Figure 4 As shown, the reaction tank in this embodiment has two protrusions: an upper protrusion 16 and a lower protrusion 17. The upper protrusion 16 is decomposed into an upper tank body patch component 23, and the lower protrusion 17 is decomposed into a lower tank body patch component 24. Thus, in this embodiment, the reaction tank is decomposed into seven components: two tank body light-transmitting surface components 21, two tank body inner curved surface components 22, an upper tank body patch component 23, a lower tank body patch component 24, and a tank bottom 30. The interface between the tank body light-transmitting surface component 21 and the tank body inner curved surface component 22 is shown below. Figure 5 As shown.

[0059] Step 2, Cutting: Use wire cutting to cut the quartz material to obtain the blanks of each part. Specifically, use wire cutting to cut the blanks of the two pool translucent surface parts 21, the two pool inner curved surface parts 22, the upper pool patch part 23, the lower pool patch part 24, and the pool bottom 30.

[0060] Step 3: Grinding: Grind the cut part blanks using a machining center. Specifically, each part blank after grinding should meet the dimensional requirements. In this embodiment, the length of the pool bottom 30 is 9.60±0.05mm, the width is 8.5±0.05mm, and the thickness is 6.00±0.05mm. The top surface of the pool bottom 30 is provided with a constriction section 14 of the reaction chamber 11. The constriction section 14 is a smooth curved surface, and its function is to transition the cylindrical section 13 of the reaction chamber 11 to the drain outlet 12. The cylindrical section 13 of the reaction chamber 11 is located inside the pool body 20, such as... Figure 5 As shown, the two opposing inner curved surfaces 13a of the cylindrical segment 13 are arc surfaces with a diameter of 6.8 mm and an arc length of 5.7-5.8 mm; the two opposing light-transmitting surfaces 13b of the cylindrical segment 13 are planes with a length of 3.0 mm, and the distance between the two opposing light-transmitting surfaces 13b is 5.6 mm. The transition surface 13c between the inner curved surface 13a and the light-transmitting surface 13b is an arc surface with a diameter of 2 mm and an arc length of 0.70-0.75 mm.

[0061] Step 4: Polishing. Polish all surfaces within the reaction chamber of each part blank, as well as all contact surfaces encountered during the assembly of the part blanks. Specifically, the polishing method is as follows:

[0062] 31) Polishing the inner surface of the reaction chamber: The inner surfaces of the curved parts 22 inside the two pools, the inner surfaces of the light-transmitting parts 21 inside the two pools, and the upper surface of the bottom 30 of the pool, which serves as the closing section 14 of the reaction chamber, are polished using an oxyhydrogen flame polisher. Specifically, in this embodiment, the polishing temperature of the oxyhydrogen flame polisher is 1900-2000℃, and the polishing time is 2-4 hours. Then, the inner surfaces of the light-transmitting parts 21 inside the two pools are polished using a ring mill, so that the roughness of the inner surfaces of the light-transmitting parts 21 inside the two pools reaches the nanometer level.

[0063] 32) Polishing contact surfaces: Polish the contact surfaces of the bottom of the pool 30, the upper pool body patch part 23, the lower pool body patch part 24, the two pool body light-transmitting surface parts 21, and the two pool body inner curved surface parts 22 that need to be bonded with other parts during bonding using a ring mill, so that the roughness of all contact surfaces reaches the nanometer level.

[0064] Specifically, during the polishing process, after 3 hours of grinding, the optometrist needs to determine whether the roughness has met the set requirements: if yes, then polishing is complete; if not, then the polishing pad and polishing fluid need to be replaced and polishing should continue until the roughness meets the set requirements.

[0065] Step 5: Assembly, Drilling, and Annealing: All parts are assembled into the reaction tank product using bonding. Through holes are machined into the reaction tank product, and then it undergoes annealing. Specifically, this includes the following steps:

[0066] 51) In a vacuum chamber within a Class 10,000 or higher cleanroom, the curved surface parts 22 and the light-transmitting surface parts 21 of the two pool bodies are sequentially bonded to obtain a first assembly. Then, the first assembly is bonded to the bottom of the pool to obtain a second assembly, as follows: Figure 6 As shown, the second assembly is left to stand for a set time. In this embodiment, the second assembly is left to stand for at least 30 minutes.

[0067] 52) The second assembly is annealed. Specifically, it is heated uniformly from 200°C to 1200±100°C in an annealing furnace for 14 hours, held for 4 hours, and then cooled to 200°C for another 14 hours before being taken out of the furnace and cooled to room temperature.

[0068] 53) The outer surface of the bonding pool patch parts of the second assembly is polished to a nanoscale roughness using a ring mill. Specifically, in this embodiment, the upper pool patch part 23 and the lower pool patch part 24 are both bonded to the outer surface of the same side of the second assembly corresponding to one of the inner curved surfaces 13a, and the outer surface is polished to a nanoscale roughness.

[0069] 54) After bonding the pool body patch parts to the corresponding outer surfaces of the second assembly, a third assembly is obtained. That is, the upper pool body patch part 23 and the lower pool body patch part 24 are bonded to the outer surfaces of the second assembly after polishing in step 53), respectively, to obtain the third assembly. Figure 7 As shown. The third assembly is left to stand for a set time; in this embodiment, the third assembly is left to stand for at least 30 minutes.

[0070] 55) Anneal the third assembly. Specifically, in the annealing furnace, the temperature is uniformly increased from 200°C to 1200±100°C over 14 hours, held for 4 hours, and then cooled to 200°C over another 14 hours before being removed from the furnace and cooled to room temperature.

[0071] 56) Drilling is performed at the designated position of the third assembly to obtain the reaction tank product. Holes are drilled on the upper tank patch part 23 and the lower tank patch part 24 to obtain through holes 15 that communicate with the reaction chamber.

[0072] 57) Anneal the product from the reaction tank. Specifically, in the annealing furnace, the temperature is uniformly increased from 200℃ to 1200±100℃ over 14 hours, held for 4 hours, and then cooled to 200℃ over another 14 hours before being removed from the furnace and cooled to room temperature.

[0073] Step 6: Cleaning: After ultrasonically cleaning the product in the reaction tank, dry it.

[0074] The embodiments described above are merely preferred embodiments for fully illustrating the present invention, and the scope of protection of the present invention is not limited thereto. Equivalent substitutions or modifications made by those skilled in the art based on the present invention are all within the scope of protection of the present invention. The scope of protection of the present invention is defined by the claims.

Claims

1. A method for processing a quartz reaction cell, characterized in that: The quartz reaction tank includes a reaction tank body made of quartz material, a reaction chamber with an opening at the top inside the reaction tank body, and a drain outlet at the bottom of the reaction chamber; The reaction chamber includes a cylindrical section at the top and a tapering section at the bottom; the cylindrical section includes two opposing inner curved surfaces and two opposing light-transmitting surfaces, with a transition surface between adjacent inner curved surfaces and light-transmitting surfaces, the transition surface making the corresponding inner curved surface and light-transmitting surface transition smoothly; the tapering section gradually narrows the bottom surface of the reaction chamber to the drain port along the direction from top to bottom; The outer side wall of the reaction tank body corresponding to the inner curved surface is provided with a protrusion, and the protrusion is provided with a through hole that communicates with the reaction chamber; The sidewalls of the reaction tank body corresponding to the light-transmitting surface are made of light-transmitting quartz material; The method includes the following steps: Step 1: Decomposition: Based on the structural model of the reaction tank, decompose the reaction tank into multiple parts that are easy to cut and process; Step 2, Cutting: Use wire cutting to cut the quartz material to obtain the blanks of each part; Step 3, Grinding: Grinding and cutting to obtain the part blank; Step 4, Polishing: Polish all surfaces in each part blank that serve as the inner surface of the reaction chamber, and polish all contact surfaces during the assembly of the part blanks; Step 5: Assembly, Drilling, and Annealing: Assemble all parts into a reaction tank product by bonding, machine through holes in the reaction tank product, and anneal the reaction tank product. Step 6: Cleaning: After cleaning the product in the reaction tank, dry it. In step one, the method for decomposing the reaction tank is as follows: 11) The reaction tank is decomposed into a tank body and a tank bottom, wherein the decomposition surface of the tank body and the tank bottom is the interface between the cylindrical section and the constriction section of the reaction chamber. 12) Decompose the parts corresponding to the two light-transmitting surfaces of the pool body and the reaction chamber into two pool body light-transmitting surface parts, and decompose the parts between the two pool body light-transmitting surface parts into inner curved surface parts of the pool body; decompose the protruding parts on the inner curved surface parts of the pool body into pool body patch parts. In step two, wire cutting is used to cut part blanks for the pool bottom, pool body patch parts, two pool body light-transmitting surface parts, and two pool body inner curved surface parts.

2. The method for processing a quartz reaction cell according to claim 1, characterized in that: In step four, the polishing method is as follows: 31) Polishing the inner surface of the reaction chamber: The inner surfaces of the curved parts inside the two pools, the inner surfaces of the light-transmitting parts in the two pools, and the upper surface of the bottom of the pools serving as the closing section of the reaction chamber are polished using an oxyhydrogen flame polishing machine. Then, the inner surfaces of the light-transmitting parts of the two pools were polished using a ring mill, so that the roughness of the inner surfaces of the light-transmitting parts of the two pools reached the nanometer level. 32) Polishing contact surfaces: The contact surfaces of the pool bottom, pool body patch parts, two pool body light-transmitting surface parts, and two pool body inner curved surface parts are polished using a ring mill to achieve a roughness of nanometer level for all contact surfaces.

3. The method for processing a quartz reaction cell according to claim 2, characterized in that: The polishing temperature of the oxyhydrogen flame polishing machine is 1900-2000℃, and the polishing time is 2-4 hours.

4. The method for processing a quartz reaction cell according to claim 1, characterized in that: Step five includes the following steps: 51) Bond the two inner curved surface parts and the two inner light-transmitting surface parts of the pool in sequence to obtain the first assembly, and then bond the first assembly to the bottom of the pool to obtain the second assembly. Let the second assembly stand for a set time. 52) Anneal the second assembly; 53) Use a ring mill to polish the outer surface of the bonding pool patch parts of the second assembly to a nanoscale roughness. 54) After bonding the pool body patch parts to the corresponding outer surface of the second assembly, the third assembly is obtained. The third assembly is then left to stand for a set time. 55) Anneal the third assembly; 56) Drilling is performed at the designated position of the third assembly to obtain the reaction tank product; 57) Anneal the product from the reaction tank.

5. The method for processing a quartz reaction cell according to claim 4, characterized in that: The method for annealing the second assembly, the third assembly, and the product from the reaction tank is as follows: starting from 200°C in the annealing furnace, the temperature is uniformly increased to 1200±100°C over 14 hours, then held for 4 hours, and then cooled to 200°C over another 14 hours before being removed from the furnace and cooled to room temperature.

6. A quartz reaction cell, characterized in that: It is processed using the quartz reaction cell processing method as described in any one of claims 1-5.

7. The quartz reaction cell according to claim 6, characterized in that: The protrusion is provided in two parts, namely an upper protrusion and a lower protrusion. The upper protrusion is located above the lower protrusion, and the upper protrusion and the lower protrusion are respectively provided with through holes that communicate with the reaction chamber.

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