一种基于FTICR-MS提升溶解有机质离子峰的标准化流程和方法
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- GUANGDONG INST OF ANALYSIS CHINA NAT ANALYTICAL CENT GUANGZHOU
- Filing Date
- 2022-12-13
- Publication Date
- 2026-07-17
AI Technical Summary
Existing FTICR-MS technology suffers from insufficient methods and standardization in measuring the signal intensity of dissolved organic matter ion peaks, leading to inconsistent results between laboratories and making comparisons difficult. Furthermore, the complexity of instrument parameter settings can result in component loss or incorrect molecular formulas.
By employing standardized parameters such as concentration, flow rate, ion accumulation time, and purge voltage, and combining a micro-spray device with Fourier transform resonance cyclotron mass spectrometry, standardized data acquisition density and relative intensity representation data are established to ensure comparability and reproducibility among different laboratories.
It improves the intensity and reproducibility of quasi-molecular ion peaks of dissolved organic compounds, reduces peak drift, achieves comparability between different samples, avoids human differences caused by improper instrument calibration, and improves resolution and data consistency.
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