一种判别G-四链体结构DNA的方法
By analyzing the characteristics of DNA base repeat units and rectangular block diagrams, the problem of the difficulty in quickly identifying G-quadruplex DNA structures in existing technologies has been solved, enabling rapid and accurate DNA structure identification and molecular-level research.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES
- Filing Date
- 2023-01-04
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies are insufficient for rapidly identifying G-quadruplex DNA structures at the molecular level. Current methods can only characterize DNA conformations macroscopically and lack rapid molecular-level identification methods.
By analyzing the base repeating unit characteristics of the DNA structure to be determined, the effective active region is identified, the base sorting characteristics and rectangular box diagram are drawn, the distribution pattern of the rectangular boxes is determined, and it is determined whether the DNA is a G-quadruplex structure.
This technology enables rapid and accurate identification of G-quadruplex DNA structures, reducing analytical difficulty and cost, providing molecular-level research evidence, and supporting research on the recognition mechanism of G-quadruplex DNA interactions with small molecules.
Smart Images
Figure CN116230072B_ABST