Biological detection device
Patent Information
- Application Number
- CN202211721667.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-12-30
- Publication Date
- 2026-09-04
- Estimated Expiration
- 2042-12-30
AI Technical Summary
[0002]现有技术中,生物检测装置检测前需要手动驱动托架或者通过装置上的按键控制驱动电机等方式控制托架运送生物芯片到达目标位置,由此会导致人手直接与生物检测装置接触,会污染生物芯片内的样品,或者污染生物检测装置内的检测环境,影响检测结果,降低了生物检测装置的可靠性,存在改进空间
[0003] The present invention aims to at least partially solve one of the aforementioned technical problems in the prior art. To this end, the present invention proposes a biological detection device that avoids direct contact between human hands and the device, greatly reducing the possibility of contaminating the sample within the biochip or the detection environment within the device, thereby improving the reliability of the detection results.
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Figure CN116240102B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of biological detection technology, and more specifically, to a biological detection device. Background Technology
[0002] In existing technologies, biological detection devices require manual operation of the tray or control of the drive motor via buttons on the device to transport the biochip to the target location before detection. This results in direct contact between the human hand and the biological detection device, which can contaminate the sample inside the biochip or the detection environment inside the device, affecting the detection results and reducing the reliability of the biological detection device. There is room for improvement. Summary of the Invention
[0003] The present invention aims to at least partially solve one of the aforementioned technical problems in the prior art. To this end, the present invention proposes a biological detection device that avoids direct contact between human hands and the device, greatly reducing the possibility of contaminating the sample within the biochip or the detection environment within the device, thereby improving the reliability of the detection results.
[0004] The present invention also proposes a biological detection device having the above-mentioned biological detection device.
[0005] According to a first aspect of the present invention, a biological detection device includes: a mounting bracket; a tray for carrying a biochip, the tray being movably disposed on the mounting bracket in a horizontal direction between a sample application position and a detection position; a first driving component connected to the tray for driving the tray to move; a gesture recognition system for recognizing control gestures; and a control system communicating with the gesture recognition system for controlling the operating state of the first driving component based on the recognition result of the gesture recognition system to drive the tray to move toward or away from the detection position.
[0006] According to the biological detection device of the present invention, the biological detection device avoids direct contact between human hands and the biological detection device, greatly reducing the possibility of contaminating the sample inside the biochip or the detection environment inside the biological detection device, and improving the reliability of the detection results of the biological detection device.
[0007] In addition, the biological detection device according to the embodiments of the invention may also have the following additional technical features:
[0008] According to some embodiments of the present invention, the gesture recognition system includes: an acquisition module for acquiring change information of control gestures; and a processing module for communicating with the acquisition module for processing the change information of control gestures acquired by the acquisition module, and for recognizing and interpreting it. The control system controls the operating state of the first driving component according to the recognition result of the processing module.
[0009] According to some embodiments of the present invention, the acquisition module includes multiple sets, and the multiple sets of acquisition modules communicate with the processing module simultaneously.
[0010] According to some embodiments of the present invention, the processing module includes: an extraction unit, which is used to extract the change information of the control gesture acquired by the acquisition module into a calculable amount of information; and an identification unit, which is used to identify and interpret the amount of information.
[0011] According to some embodiments of the present invention, the acquisition module includes: an infrared emitting unit for emitting infrared light; and an infrared receiving unit for receiving the infrared light emitted by the infrared emitting unit reflected by the control gesture, and acquiring the change information of the control gesture based on the intensity change of the infrared light.
[0012] According to some embodiments of the present invention, the infrared emitting unit includes a plurality of infrared emitting units, which are evenly distributed around the infrared receiving unit.
[0013] According to some embodiments of the present invention, the infrared emitting unit includes a driver and an infrared light source, the driver being adapted to drive the infrared light source to emit infrared light, and the driver communicating with the control system.
[0014] According to some embodiments of the present invention, the first driving component includes a driving motor, and the control system is adapted to control the driving motor to rotate forward or reverse according to the recognition result of the gesture recognition system; wherein, when the driving motor rotates forward, it is adapted to drive the bracket to move toward the detection position, and when the driving motor rotates in reverse, it is adapted to drive the bracket to move away from the detection position.
[0015] According to some embodiments of the present invention, the first drive assembly further includes a transmission screw, and the drive motor is connected to the transmission screw; wherein the transmission screw is provided with an external thread, the bracket is provided with a mating hole, the inner wall of the mating hole is provided with an internal thread, the transmission screw passes through the mating hole, and the external thread mates with the internal thread.
[0016] According to some embodiments of the present invention, the biological detection device further includes a heating module disposed below the bracket for heating the biochip when the bracket moves to the detection position. Attached Figure Description
[0017] Figure 1 This is a structural block diagram of the various modules of the biological detection device according to an embodiment of the present invention;
[0018] Figure 2 This is a schematic diagram of the structure of a biological detection device according to an embodiment of the present invention;
[0019] Figure 3 This is a partial structural diagram of the acquisition module according to an embodiment of the present invention;
[0020] Figure 4 This is a schematic diagram of the structure of a biological detection device according to an embodiment of the present invention;
[0021] Figure 5 This is a schematic diagram of the structure of a biological detection device according to an embodiment of the present invention;
[0022] Figure 6 This is a partial structural schematic diagram of a biological detection device according to an embodiment of the present invention;
[0023] Figure 7 This is a partial structural schematic diagram of a biological detection device according to an embodiment of the present invention;
[0024] Figure 8 This is a partial structural schematic diagram of a biological detection device according to an embodiment of the present invention.
[0025] Figure label:
[0026] The biological detection device 100 includes a first driving component 10, a gesture recognition system 20, an acquisition module 201, an infrared emitting unit 2011, a driver 20111, an infrared light source 20112, an infrared receiving unit 2012, a processing module 202, an extraction unit 2021, an identification unit 2022, a control system 30, a front panel 40, a door 50, a mounting bracket 1, a second driving component 11, a slide rail 12, a bracket 2, a biochip 3, a mating part 31, a heating module 4, a conveying component 5, an output part 51, a mounting plate 52, a pressure plate 6, a clearance hole 61, a first spring 7, a second spring 8, a second guide post 81, a mounting base 9, and a slider 91. Detailed Implementation
[0027] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.
[0028] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.
[0029] The biological detection device of this invention is suitable for quantitative detection of nucleic acid molecules. During the detection process of the biological detection device, the biochip to be detected needs to be transported to the detection location for droplet generation and amplification, or the biochip needs to be transported outside the biological detection device.
[0030] In existing technologies, biological detection devices require manual operation of the tray or control of the drive motor via buttons on the device to transport the biochip to the target location before detection. This results in direct contact between the human hand and the biological detection device, which can contaminate the sample inside the biochip or the detection environment inside the biological detection device, affecting the detection results and reducing the reliability of the biological detection device.
[0031] Therefore, this invention provides a biological detection device 100 that controls the bracket 2 to move horizontally between the sample application position and the detection position based on the recognition result of the gesture recognition system 20. This avoids direct contact between human hands and the biological detection device 100, greatly reducing the possibility of contaminating the sample in the biochip 3 or the detection environment in the biological detection device 100, and improving the reliability of the detection results of the biological detection device 100.
[0032] The following is for reference. Figures 1-8 A biological detection device 100 according to an embodiment of the present invention is described.
[0033] The biological detection device 100 according to an embodiment of the present invention may include: a mounting bracket 1, a bracket 2, a first driving component 10, a gesture recognition system 20, and a control system 30.
[0034] The mounting bracket 1 serves to support the entire biological detection device 100, ensuring the stability of the overall structure of the biological detection device 100. The biochip 3 is used to store biological samples, and the biochip 3 needs to be replaced after a set of biochips 3 has been used for detection.
[0035] The bracket 2 is used to carry the biochip 3. The biochip 3 can move with the movement of the bracket 2. The bracket 2 is movably mounted on the mounting bracket 1 between the sample application position and the detection position in the horizontal direction. Thus, the bracket 2 can move in the horizontal direction to the sample application position outside the biological detection device 100. At the sample application position, the user can easily replace the biochip 3 carried on the bracket 2. After the sample application is completed, the bracket 2 can move in the horizontal direction to the detection position inside the biological detection device 100, and complete the droplet generation and amplification process at the detection position.
[0036] Furthermore, the first drive assembly 10 is connected to the bracket 2 and is used to drive the bracket 2 to move. By controlling the first drive assembly 10 to operate in different states, the bracket 2 can be controlled to move towards the sample application position or towards the detection position.
[0037] The gesture recognition system 20 is used to recognize control gestures. The control system 30 communicates with the gesture recognition system 20. The control system 30 can control the operation of the first drive component 10 based on the recognition result of the gesture recognition system 20. The control system 30 is used to control the operating state of the first drive component 10 based on the recognition result of the gesture recognition system 20 to drive the bracket 2 to move towards or away from the detection position.
[0038] Specifically, the gesture recognition system 20 can pre-store the original data of the first control gesture and the second control gesture. When the user makes a control gesture in front of the gesture recognition system 20, the gesture recognition system 20 can recognize the control gesture and compare the information of the control gesture obtained with the original data of the first control gesture and the second control gesture pre-stored in the system. When the obtained control gesture information is the same as the original data of the first control gesture, the gesture recognition system 20 transmits the information to the control system 30. The control system 30 controls the operating state of the first drive component 10 according to the information obtained by the gesture recognition system 20 to drive the bracket 2 to move toward the detection position.
[0039] When the acquired control gesture information is the same as the original data of the second control gesture, the gesture recognition system 20 transmits the information to the control system 30. The control system 30 controls the operating state of the first drive component 10 according to the information acquired by the gesture recognition system 20 to drive the bracket 2 to move away from the detection position.
[0040] In other embodiments, the control system 30 may pre-store the original data of the first and second control gestures. When a user makes a control gesture in front of the gesture recognition system 20, the gesture recognition system 20 can recognize the control gesture and transmit the acquired control gesture information to the control system 30. The control system 30 compares this information with the pre-stored original data of the first and second control gestures. When the acquired control gesture information is the same as the original data of the first control gesture, the control system 30 controls the operation of the first drive component 10 to drive the bracket 2 to move towards the detection position. When the acquired control gesture information is the same as the original data of the second control gesture, the control system 30 controls the operation of the first drive component 10 to drive the bracket 2 to move away from the detection position.
[0041] According to the embodiment of the present invention, the biological detection device 100 avoids direct contact between human hands and the biological detection device 100, greatly reducing the possibility of contaminating the sample in the biochip 3 or contaminating the detection environment in the biological detection device 100, and improving the reliability of the detection results of the biological detection device 100.
[0042] like Figure 4 As shown, the first drive component 10 includes a drive motor, and the control system 30 is adapted to control the drive motor to rotate forward or reverse according to the recognition result of the gesture recognition system 20. By controlling the drive motor to rotate forward or reverse, the movement direction of the bracket 2 can be controlled. When the drive motor rotates forward, it is adapted to drive the bracket 2 to move towards the detection position, and when the drive motor rotates in reverse, it is adapted to drive the bracket 2 to move away from the detection position.
[0043] Alternatively, in other embodiments, when the drive motor reverses, it is suitable to drive the bracket 2 to move toward the detection position, and when the drive motor rotates forward, it is suitable to drive the bracket 2 to move away from the detection position.
[0044] In some embodiments, the first drive assembly 10 further includes a transmission screw, and the drive motor is connected to the transmission screw. When the drive motor rotates forward, it is adapted to drive the transmission screw to rotate forward, and the transmission screw drives the bracket 2 to move toward the detection position. When the drive motor rotates in reverse, it is adapted to drive the transmission screw to rotate in reverse, and the transmission screw drives the bracket 2 to move away from the detection position.
[0045] The transmission screw has an external thread, the bracket 2 has a mating hole, the inner wall of the mating hole has an internal thread, the transmission screw passes through the mating hole, and the external thread and the internal thread are mated.
[0046] Reference Figure 1The gesture recognition system 20 includes an acquisition module 201 and a processing module 202. The acquisition module 201 is used to acquire information about control gestures. The processing module 202 communicates with the acquisition module 201 and is used to process the information about control gestures acquired by the acquisition module 201, and to recognize and interpret it. The control system 30 controls the operating state of the first drive component 10 according to the recognition result of the processing module 202.
[0047] Specifically, when a user makes a control gesture in front of the gesture recognition system 20, the acquisition module 201 can acquire the information of the control gesture. Different signals are generated depending on the different gestures or the different gesture positions. These signals are transmitted to the processing module 202, acquired by the processing module 202, and the information acquired by the acquisition module 201 is extracted into calculable information. Then, these calculable information are identified and interpreted.
[0048] The gesture recognition system 20 can pre-store the original data of the first control gesture and the second control gesture. The processing module 202 compares the information obtained by the acquisition module 201 with the pre-stored original data of the first control gesture and the second control gesture. When the acquired control gesture information is the same as the original data of the first control gesture, the gesture recognition system 20 transmits the information to the control system 30. The control system 30 controls the operating state of the first drive component 10 according to the information obtained by the gesture recognition system 20 to drive the bracket 2 to move toward the detection position.
[0049] When the acquired control gesture information is the same as the original data of the second control gesture, the gesture recognition system 20 transmits the information to the control system 30. The control system 30 controls the operating state of the first drive component 10 according to the information acquired by the gesture recognition system 20 to drive the bracket 2 to move away from the detection position.
[0050] In some embodiments, the acquisition module 201 includes multiple sets, and the multiple sets of acquisition modules 201 can acquire control gesture information simultaneously, thereby increasing the range of control gesture information acquired by the gesture recognition system 20, avoiding blind spots in the gesture recognition process, and ensuring the sensitivity of the gesture recognition system 20.
[0051] Furthermore, multiple acquisition modules 201 communicate with the processing module 202 simultaneously, and the processing module 202 judges the control gestures based on the results acquired by the multiple acquisition modules 201, which has better fault tolerance.
[0052] In other embodiments, the gesture recognition system 20 includes only one set of acquisition modules 201 to simplify the structure of the biometric detection device 100 and reduce production costs while ensuring that the gesture recognition system 20 can acquire control gesture information.
[0053] like Figure 1As shown, the acquisition module 201 includes an infrared emitting unit 2011 and an infrared receiving unit 2012. The infrared emitting unit 2011 emits infrared light, and the infrared receiving unit 2012 receives the infrared light emitted by the infrared emitting unit 2011 reflected by the control gesture, and acquires the change information of the control gesture based on the intensity change of the infrared light. The infrared receiving unit 2012 can be an infrared receiver.
[0054] Specifically, the infrared emitting unit 2011 emits infrared light, which shines on a person's hand and is then reflected back to the infrared receiving unit 2012. Depending on the gesture and the different positions of the hand, the infrared light reflected back to the infrared receiving unit 2012 can generate different signals on the infrared receiving unit 2012. These signals are extracted by the processing module 202, which extracts the signals into calculable information and then identifies and interprets this calculable information.
[0055] Reference Figure 3 The infrared emitting unit 2011 includes multiple units, which are evenly distributed around the infrared receiving unit 2012. By evenly distributing multiple infrared emitting units 2011 around the infrared receiving unit 2012, the range of control gesture information acquired by the gesture recognition system 20 can be increased, blind spots can be avoided during gesture recognition, and the sensitivity of the gesture recognition system 20 can be ensured.
[0056] Specifically, such as Figure 3 As shown, the infrared emitting unit 2011 includes four units, which are evenly arranged above, below, left, and right of the infrared receiving unit 2012. This ensures the range of control gesture information acquired by the gesture recognition system 20, avoids blind spots in the gesture recognition process, reduces the number of infrared emitting units 2011, simplifies the structure of the gesture recognition system 20, and reduces the production cost of the biological detection device 100.
[0057] like Figure 1 As shown, the infrared emitting unit 2011 includes a driver 20111 and an infrared light source 20112. The driver 20111 is adapted to drive the infrared light source 20112 to emit infrared light, and the driver 20111 communicates with the control system 30. The control system 30 controls the infrared light source 20112 to emit infrared light by controlling the driver 20111. The infrared light source 20112 can be an infrared light-emitting diode.
[0058] Reference Figure 1The processing module 202 includes an extraction unit 2021 and an identification unit 2022. The extraction unit 2021 is used to extract the information of the control gestures acquired by the acquisition module 201 into a computable amount of information, and the identification unit 2022 is used to identify and interpret the information.
[0059] Specifically, such as Figure 1 As shown, the control system 30 controls the infrared light source 20112 to emit infrared light through the control driver 20111. The infrared light emitted by the infrared light source 20112 shines on the person's hand and is reflected back to the infrared receiving unit 2012. Depending on the gesture and the different positions of the hand, the infrared light reflected back to the infrared receiving unit 2012 can generate different signals on the infrared receiving unit 2012. These signals are extracted by the extraction unit 2021, which extracts the signals into calculable information. The recognition unit 2022 then recognizes and interprets these calculable information, and the recognition result is stored in a register.
[0060] The control system 30 can preset a first control gesture and a second control gesture. The control system 30 can read the recognition result stored in the register and compare it with the preset information in the system. When the recognition result is the same as the preset information of the first control gesture, the control system 30 controls the operation of the first drive component 10 to drive the bracket 2 to move towards the detection position. When the recognition information is the same as the preset information of the second control gesture, the control system 30 controls the operation of the first drive component 10 to drive the bracket 2 to move away from the detection position.
[0061] Combination Figures 4-8 In the embodiment shown, the biological detection device 100 further includes a heating module 4, which is located below the bracket 2 and is used to heat the biochip 3 when the bracket 2 moves to the detection position, thereby heating the sample inside the biochip 3.
[0062] A first elastic element is provided between the bracket 2 and the mounting bracket 1 to drive the bracket 2 to move upward so that the bracket 2 avoids the heating device. In other words, without external force, the first elastic element can always support the bracket 2 to avoid the heating device.
[0063] Therefore, during the horizontal movement of the bracket 2 and the biochip 3, there is no external force acting vertically. The first elastic element can always support the bracket 2 to avoid the heating device. The heating module 4 is separately set from the biochip 3 and the bracket 2, which avoids the heating module 4 affecting the movement of the bracket 2. The heating module 4 does not need to move with the bracket 2, which simplifies the structure of the biological detection device 100. The removal and placement of the biochip 3 is more convenient, and the high temperature of the heating module 4 during the removal and placement of the biochip 3 is avoided from causing injury to the human hand, thus improving the safety of the biological detection device 100.
[0064] Combination Figures 4-8 In the illustrated embodiment, the biological detection device 100 further includes a delivery component 5, which is capable of docking with the biochip 3 to deliver a medium to the biochip 3 to achieve droplet generation. The delivery component 5 is movably mounted on the mounting bracket 1 in the vertical direction. After the bracket 2 moves horizontally to the detection position inside the biological detection device 100, the delivery component 5 moves downward until it docks with the biochip 3. After docking, the delivery component 5 is adapted to deliver a medium to the biochip 3. After the medium delivery is completed, the delivery component 5 can move upward to separate the delivery component 5 from the biochip 3. The delivery component 5 can be reused during the detection process.
[0065] like Figures 4-5 As shown, the biological detection device 100 further includes a second drive assembly 11, which is mounted on the mounting bracket 1 and connected to the conveying assembly 5, for driving the conveying assembly 5 to move in the up and down direction.
[0066] Reference Figure 5 The biological detection device 100 also includes: a mounting base 9, which is located below the bracket 2 and moves synchronously with the bracket 2 in the horizontal direction, and a first elastic element is located on the mounting base 9 and between the bracket 2 and the mounting base 9.
[0067] In other words, the mounting base 9 is movably mounted on the mounting bracket 1 in the horizontal direction, and the bracket 2 is connected to the mounting base 9 by a first elastic element so that the bracket 2 can move up and down relative to the mounting base 9 and the mounting bracket 1.
[0068] The bracket 2 and the mounting base 9 can move together horizontally to the sample application position outside the biological detection device 100. At the sample application position, the user can easily replace the biochip 3 carried on the bracket 2, which reduces the possibility of sample contamination, avoids the high temperature inside the detection device from causing injury to the user's hands, and improves the reliability and safety of the biological detection device 100.
[0069] After the sample is added, the bracket 2 and the spring seat can move horizontally to the detection position inside the biodetection device 100, and complete the heating and detection of the sample on the biochip 3 at the detection position.
[0070] Reference Figure 5 The first elastic element is the first spring 7. One of the mounting base 9 and the bracket 2 is provided with a first guide post extending in the vertical direction and the other is provided with a first guide hole. The first guide post and the first guide hole are slidably engaged. The first spring 7 is sleeved on the first guide post.
[0071] The cooperation between the first guide post and the first guide hole not only guides the up-and-down movement of the bracket 2, ensuring stable movement of the bracket 2 in the up-and-down direction, but also connects the mounting base 9 and the bracket 2, ensuring the stability of the connection between the mounting base 9 and the bracket 2.
[0072] In some embodiments, a first limiting member is provided on the first guide post. The first limiting member can limit the movement of the bracket 2 in the vertical direction to prevent the bracket 2 from displacing too much in the vertical direction and detaching from the mounting base 9.
[0073] like Figure 4 and Figure 5 As shown, the mounting bracket 1 is provided with at least two spaced slide rails 12, each slide rail 12 extending horizontally. A slider 91 is provided on the side wall of the mounting base 9, and the slider 91 slides in cooperation with the slide rail 12. The slide rail 12 guides the bracket 2 and mounting base 9 during horizontal movement, ensuring smoother movement and stability of the bracket 2.
[0074] The bracket 2 is located between two slide rails 12, which together support the bracket 2 from both sides, ensuring the stability of the bracket 2.
[0075] Combination Figures 4-8 In the embodiment shown, the biological detection device 100 further includes a pressure plate 6, and the conveying assembly 5 further includes a mounting plate 52. The mounting plate 52 is disposed above the pressure plate 6. Multiple output parts 51 are fixed to the mounting plate 52. The biochip 3 has multiple mating parts 31. The multiple output parts 51 are adapted to correspond one-to-one with the multiple mating parts 31, thereby enabling simultaneous detection of multiple sets of chips.
[0076] Combination Figures 6-8 In the embodiment shown, the pressure plate 6 is provided with a clearance hole 61, and the output part 51 is adapted to pass through the clearance hole 61 to cooperate with the mating part 31, so as to avoid the setting of the pressure plate 6 from affecting the normal docking of the output part 51 and the mating part 31.
[0077] A second elastic element is provided between the pressure plate 6 and the mounting plate 52 to drive the pressure plate 6 to move downward relative to the mounting plate 52. This allows the pressure plate 6 and the mounting plate 52, i.e., the output section 51 fixedly connected to the mounting plate 52, to move asynchronously. After the output section 51 has finished conveying the medium, it can move away from the biochip 3. At this time, the pressure plate 6 can remain in its original position to limit the bracket 2, ensuring that the biochip 3 remains in contact with the heating module 4. Therefore, during the heating process of the biochip 3, the output section 51 separates from the biochip 3, reducing contamination of the sample inside the biochip 3 by the output section 51.
[0078] In some embodiments, when the output component is docked with the biochip 3, the elastic force of the second elastic element is greater than that of the first elastic element. This ensures that even after the mounting plate 52 is moved a certain distance away from the pressure plate 6 in this state, the elastic force of the second elastic element remains greater than or equal to that of the first elastic element. The pressure plate 6 can remain in place to limit the bracket 2, ensuring that the biochip 3 remains in contact with the heating module 4. The greater elastic force of the second elastic element also better seals the air passage between the delivery component 5 and the biochip 3.
[0079] Reference Figure 5 The second elastic element is the second spring 8. One of the pressure plate 6 and the mounting plate 52 is provided with a second guide post 81 extending in the vertical direction, and the other is provided with a second guide hole. The second guide post 81 and the second guide hole are slidably engaged. The second spring 8 is sleeved on the second guide post 81.
[0080] The cooperation between the second guide post 81 and the second guide hole not only guides the up-and-down movement of the pressure plate 6 relative to the conveying assembly 5, ensuring the stability of the pressure plate 6 in the up-and-down direction, but also connects the pressure plate 6 and the mounting plate 52, ensuring the stability of the connection between the pressure plate 6 and the mounting plate 52.
[0081] In some embodiments, the second guide post 81 is provided with a second limiting member, which can limit the pressure plate 6 to prevent the pressure plate 6 from detaching from the mounting plate 52.
[0082] Combination Figures 1-8 Describe the specific operation process of the biological detection device 100.
[0083] The control system 30 controls the infrared light source 20112 to emit infrared light through the control driver 20111. The user can make a second control gesture in front of the acquisition module 201 on the front panel 40. The infrared light emitted by the infrared light source 20112 shines on the user's hand and is reflected back to the infrared receiving unit 2012, generating a signal on the infrared receiving unit 2012. The signal is extracted by the extraction unit 2021, which extracts the signal into calculable information. The recognition unit 2022 then recognizes and interprets this calculable information, and the recognition result is stored in a register.
[0084] The control system 30 can contain the original data of the first control gesture and the second control gesture. The control system 30 can read the recognition result stored in the register and compare it with the original data of the first control gesture and the second control gesture in the system. When the recognition result is the same as the original data of the second control gesture, the control system 30 controls the door 50 to open and the first drive component 10 to reverse to drive the bracket 2 to move away from the detection position.
[0085] At this time, the bracket 2 and the mounting base 9 can move together horizontally to the sample addition position outside the biological detection device 100. At the sample addition position, the user can easily replace the biochip 3 carried on the bracket 2, which reduces the possibility of sample contamination, avoids the high temperature inside the detection device from causing injury to the human hand, and improves the reliability and safety of the biological detection device 100.
[0086] After the sample is added, the control system 30 controls the infrared light source 20112 to emit infrared light through the control driver 20111. The user can make a first control gesture in front of the acquisition module 201 on the front panel 40. The infrared light emitted by the infrared light source 20112 shines on the user's hand and is reflected back to the infrared receiving unit 2012, generating a signal on the infrared receiving unit 2012. The signal is extracted by the extraction unit 2021, which extracts the signal into calculable information. The recognition unit 2022 then recognizes and interprets this calculable information, and the recognition result is stored in a register.
[0087] The control system 30 can read the recognition result stored in the register and compare it with the original data of the first control gesture and the second control gesture in the system. When the recognition result is the same as the original data of the first control gesture, the control system 30 controls the first drive component 10 to rotate forward to drive the bracket 2 to move toward the detection position.
[0088] At this time, the bracket 2 and the spring seat can move horizontally to the detection position inside the biodetection device 100 and close the chamber door 40. The biochip 3 completes the heating and detection of the sample on the biochip 3 at the detection position.
[0089] At the detection position, the conveying assembly 5 is located above the detection position and is movably mounted on the mounting bracket 1 in the vertical direction. The conveying assembly 5 includes a mounting plate 52 and multiple output parts 51. The multiple output parts 51 are fixed to the mounting plate 52. The mounting plate 52 is located above the pressure plate 6. A second elastic element is provided between the pressure plate 6 and the mounting plate 52.
[0090] The pressure plate 6 is connected to the mounting plate 52 by a second elastic element, which is used to drive the pressure plate 6 to move downward relative to the mounting plate 52.
[0091] With the bracket 2 in the detection position directly below the pressure plate 6, the second drive assembly 11 is adapted to simultaneously drive the mounting plate 52, the output section 51, and the pressure plate 6 until the pressure plate 6 contacts the biochip 3.
[0092] After the pressure plate 6 comes into contact with the biochip 3, the distance between the pressure plate 6 and the mounting plate 52 decreases, the second elastic element is compressed, and the elastic force of the second elastic element provides a downward force to the pressure plate 6, thereby driving the biochip 3 and the bracket 2 to move downward. At the same time, the first elastic element is compressed until the biochip 3 comes into contact with the heating module 4.
[0093] like Figure 7 As shown, after the biochip 3 comes into contact with the heating module 4, the pressure plate 6, the biochip 3 and the bracket 2 are limited by the heating module 4. The length of the first elastic member remains unchanged. The second driving component 11 drives the mounting plate 52 and the output part 51 to continue to move downward. The second elastic member is further compressed until the output part 51 docks with the mating part 31 on the biochip 3. The output part 51 delivers the medium to the biochip 3 to realize the generation of droplets.
[0094] Reference Figure 8 After the medium delivery is completed, since the elastic force of the second elastic element is greater than that of the first elastic element, the second drive assembly 11 is adapted to drive the mounting plate 52 and the output part 51 to move upward a certain distance, so that the output part 51 separates from the mating part 31, and keeps the positions of the pressure plate 6, the biochip 3, and the bracket 2 unchanged. The pressure plate 6 can remain in place to limit the bracket 2, ensuring that the biochip 3 remains in contact with the heating module 4. After the output part 51 separates from the mating part 31, the heating module 4 is activated to heat the biochip 3.
[0095] After the heating process is completed, the second drive assembly 11 is adapted to drive the mounting plate 52 and the output part 51 to continue to move upward. The pressure plate 6 is adapted to move together away from the bracket 2 and the biochip 3 under the drive of the mounting plate 52. At this time, the bracket 2 and the biochip 3 lose the restriction of the pressure plate 6 above. The elastic potential energy stored in the first elastic member can drive the bracket 2 to move upward so that the bracket 2 avoids the heating device.
[0096] It should be noted that, unless otherwise specified, the embodiments and features described in the present invention can be combined with each other.
[0097] Other structures of the biological detection device are already known to those skilled in the art and are not described in detail here.
[0098] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0099] Although embodiments of the invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.
Claims
1. A biological detection device, characterized in that, include: Mounting bracket; A tray for holding a biochip, the tray being movably disposed in the mounting bracket along the horizontal direction between a sample application position and a detection position; A first drive assembly, connected to the bracket, is used to drive the bracket to move; A gesture recognition system, wherein the gesture recognition system is used to recognize control gestures; A control system, which communicates with the gesture recognition system, is used to control the operating state of the first driving component according to the recognition result of the gesture recognition system so as to drive the bracket to move toward or away from the detection position; A heating module is provided below the bracket and is used to heat the biochip when the bracket moves to the detection position; A first elastic element is provided between the bracket and the mounting bracket to drive the bracket to move upward so that the bracket avoids the heating device; Delivery components, which can be used to interface with biochips to deliver media to the biochips; The second drive assembly is mounted on the mounting bracket and connected to the conveying assembly, and is used to drive the conveying assembly to move in the vertical direction. Mounting base, the mounting base is located below the bracket and moves synchronously with the bracket in the horizontal direction, the first elastic element is located on the mounting base and between the bracket and the mounting base; The pressure plate and the conveying assembly also include a mounting plate, which is located above the pressure plate. Multiple outputs are fixed to the mounting plate. The biochip has multiple mating parts, and the multiple outputs are adapted to correspond one-to-one with the multiple mating parts. The pressure plate is provided with a clearance hole, and the output part is adapted to pass through the clearance hole to mate with the mating part; A second elastic element is provided between the pressure plate and the mounting plate to drive the pressure plate to move downward relative to the mounting plate; The elastic force of the second elastic element is greater than that of the first elastic element.
2. The biological detection device according to claim 1, characterized in that, The gesture recognition system includes: The acquisition module is used to acquire information about control gestures; The processing module communicates with the acquisition module to process, identify, and interpret the control gesture information acquired by the acquisition module. The control system controls the operating state of the first drive component based on the identification result of the processing module.
3. The biological detection device according to claim 2, characterized in that, The acquisition module includes multiple sets, and these multiple sets of acquisition modules communicate with the processing module simultaneously.
4. The biological detection device according to claim 2, characterized in that, The processing module includes: Extraction unit, the extraction unit is used to extract the control gesture information acquired by the acquisition module into a calculable amount of information; The identification unit is used to identify and interpret the information.
5. The biological detection device according to claim 2, characterized in that, The acquisition module includes: Infrared emitting unit, used to emit infrared light; An infrared receiving unit is used to receive infrared light emitted by the infrared emitting unit reflected by the control gesture, and to obtain the change information of the control gesture based on the intensity change of the infrared light.
6. The biological detection device according to claim 5, characterized in that, The infrared emitting unit comprises multiple units, which are evenly distributed around the infrared receiving unit.
7. The biological detection device according to claim 5, characterized in that, The infrared emitting unit includes a driver and an infrared light source. The driver is adapted to drive the infrared light source to emit infrared light, and the driver communicates with the control system.
8. The biological detection device according to any one of claims 1-7, characterized in that, The first driving component includes a drive motor, and the control system is adapted to control the drive motor to rotate forward or in reverse according to the recognition result of the gesture recognition system; Specifically, when the drive motor rotates forward, it is adapted to drive the bracket to move toward the detection position, and when the drive motor rotates in reverse, it is adapted to drive the bracket to move away from the detection position.
9. The biological detection device according to claim 8, characterized in that, The first drive assembly further includes a lead screw, and the drive motor is connected to the lead screw; The transmission screw has an external thread, the bracket has a mating hole, the inner wall of the mating hole has an internal thread, the transmission screw passes through the mating hole, and the external thread mates with the internal thread.
Citation Information
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