一种珍珠多肽提取物及其在制备胶原纤维再生促进剂中的应用

Pearl polypeptides with a molecular weight <2000 Da were isolated by extraction with acetic acid-hydrochloric acid-water solution and dialysis combined with purification with SP-Sephadex G-25 packed column. This solved the problem of unclear skin care ingredients in pearl powder and achieved efficient collagen fiber regeneration and high-purity extraction.

CN116333034BActive Publication Date: 2026-07-17ZHEJIANG FENIX HEALTH SCI & TECH CORP LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG FENIX HEALTH SCI & TECH CORP LTD
Filing Date
2023-04-10
Publication Date
2026-07-17

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    Figure BDA0004168507470000061
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Abstract

本发明公开了一种珍珠多肽提取物及其在制备胶原纤维再生促进剂中的应用，将纳米珍珠粉加入醋酸‑盐酸‑水溶液，磁力搅拌2‑5h，再用超纯水通过300‑800Da透析袋透析，截留液上样SP‑Sephadex G‑25填料柱进行纯化，用3‑5倍柱体积的超纯水洗脱，洗脱速度0.5‑1.5mL / min，合并蛋白含量高于0.05mg / mL且有BCA显色的流出液，超滤浓缩，得到珍珠多肽提取物；本发明提取的珍珠多肽提取物提高了珍珠粉的利用率，0.015％的珍珠多肽提取物中多肽含量与5％珍珠粉中多肽含量相同，为62.65±2.85％，珍珠多肽提取流程简单易操作，可得到纯度高的样品。
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