一种响应活性氧的自组装硒肽及其制备方法和应用

By preparing self-assembled selenium peptides that are highly sensitive to reactive oxygen species, the problem of scavenging excess free radicals in the human body was solved, achieving significant antioxidant effects and enhancing the body's antioxidant capacity.

CN116355043BActive Publication Date: 2026-07-17TIANJIN UNIVERSITY OF TECHNOLOGY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
TIANJIN UNIVERSITY OF TECHNOLOGY
Filing Date
2023-04-14
Publication Date
2026-07-17

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Abstract

本发明提供了一种响应活性氧的自组装硒肽及其制备方法和应用，属于纳米材料技术领域。一种响应活性氧的自组装硒肽，包括硒氨基酸模块和自组装肽模块；所述自组装肽模块包括氨基酸序列为FF的多肽。本发明提供了一种响应活性氧的自组装硒肽，该自组装硒肽，具有响应活性氧的能力；具有可激活自组装能力，有效清除人体内有害自由基，提高机体抗氧化性能力，维持机体稳态。实验结果显示，该灵敏响应活性氧的自组装硒肽对自由基的清除能力明显大于小分子抗氧化剂药物依达拉奉和伊布硒。
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