A human blood glucose sensor with high area utilization and a preparation method thereof

The human blood glucose sensor with high area utilization, fabricated by a symmetrically distributed seven-electrode design and screen printing technology, solves the problems of low electrode utilization and inaccurate calibration of existing sensors, and achieves more accurate blood glucose monitoring and sensor miniaturization.

CN116359306BActive Publication Date: 2025-10-24TIANJIN UNIV
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Patent Information

Application Number
CN202310353676.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-04-05
Publication Date
2025-10-24
Estimated Expiration
2043-04-05

AI Technical Summary

Technical Problem

Existing human blood glucose sensor designs suffer from problems such as low electrode area utilization, wide gaps between electrodes, insufficient liquid extraction, and inaccurate calibration, leading to inaccurate blood glucose monitoring.

Method used

The device employs a symmetrically distributed design of seven electrodes, including a counterion electroosmosis extraction electrode, an extraction auxiliary electrode, a glucose sensor working electrode, a counter electrode/reference electrode, and working and reference electrodes for the first and second differential sodium ion sensors. These electrodes are connected by silver wires to achieve electrical signal conversion. A multilayer electrode structure is fabricated using screen printing technology, and specific materials are used to improve detection sensitivity and stability.

Benefits of technology

It improves the area utilization of the sensor, ensures full extraction and diffusion of body fluids, reduces concentration distribution errors, and achieves more accurate blood glucose concentration detection. The sensor is miniaturized and the material cost is low.

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Abstract

The application provides a human blood glucose sensor with high area utilization and a preparation method thereof. The human blood glucose sensor comprises counter ion electroosmotic extraction electrodes and extraction auxiliary electrodes, glucose sensor working electrodes and glucose sensor counter electrodes / reference electrodes, first differential sodium ion sensor working electrodes, second differential sodium ion sensor working electrodes and a differential sodium ion sensor reference electrode, which are arranged on a flexible substrate layer and are prepared by screen printing. The symmetrical structure design of the human blood glucose sensor can reduce the working voltage, is beneficial to avoiding errors caused by concentration distribution, realizes maximum utilization of the sensing area in a limited structure, is beneficial to miniaturization design of the device, can realize full utilization of extracted body fluid, and thus more accurate blood glucose concentration information is obtained.
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