一株氧化亚铁硫杆菌诱变菌株及其应用
The *Acidithiobacillus ferrooxidans* mutant strain BYMT-200, obtained through heavy ion beam mutagenesis screening, solves the problem of low magnetosome yield in existing technologies, achieving high-yield and high-purity magnetosome production, and is suitable for industrial applications.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY
- Filing Date
- 2023-03-29
- Publication Date
- 2026-07-17
AI Technical Summary
The existing magnetosome yield of *Thiobacillus ferrooxidans* is low and cannot meet the needs of industrialization. Furthermore, the results of existing mutagenesis methods are random and difficult to control.
Heavy ion beams were used to induce mutagenesis and screen *Thiobacillus ferrooxidans* to obtain the *Thiobacillus ferrooxidans* mutant strain BYMT-200. Irradiation with 12C6+ ion beams and screening were then conducted to increase magnetosome production and the number of magnetosomes per cell.
It significantly increased the magnetosome yield and the number of magnetosomes per cell, making it a potential strain for large-scale production. The magnetosome yield was 1.65 mg/L, the number of magnetosomes per cell was 12-16, and the magnetotaxis was stronger.
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Figure CN116410893B_ABST