An antioxidant selenium-doped graphene nanodot drug and its preparation method and application

Abstract

The present invention relates to an antioxidant selenium-doped graphene nanodot drug and a preparation method and application thereof, and relates to the technical field of drug preparation. The present invention solves the technical problem that the antioxidant treatment of MI in the prior art has poor therapeutic effect and large side effects. The antioxidant selenium-doped graphene nanodot drug of the present invention is a selenium-doped graphene nanodot modified with phenylselenol on a sheet of graphene, and its expression is Se NPs. The present invention uses phenylselenol and polyethylene glycol as raw materials to prepare the antioxidant selenium-doped graphene nanodot drug. The present invention also provides an application of the antioxidant selenium-doped graphene nanodot drug in the preparation of a drug for treating acute myocardial infarction. The antioxidant selenium-doped graphene nanodot drug of the present invention can effectively target and enrich in the ischemic myocardium to exert a therapeutic effect under the premise of ensuring the stability of the drug in a complex ischemic myocardial environment, while avoiding systemic distribution to ensure safety.

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