A method for improving the level of kanamycin fermentation

CN116536384BActive Publication Date: 2026-03-20LIVZON GROUP FUZHOU FUXING PHARMACEUTICAL CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-05-15
Publication Date
2026-03-20

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Abstract

The present application belongs to the technical field of biological fermentation, and particularly relates to a method for improving kanamycin fermentation level. The method comprises using corn gluten meal as a fermentation organic nitrogen source, supplementing methionine to the fermentation liquor in a continuous feeding mode after fermentation culture for at least 20 hours in a fed-batch fermentation mode. The method provided by the present application can effectively reduce the content of kanamycin B in the fermentation product kanamycin, and can improve the kanamycin fermentation level and the quality of the fermentation product.
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Citation Information

Patent Citations

  • High-yield fermentation production method for daunorubicin

    CN105838760A

  • Method for producing kanamycin through fermentation

    CN106498010A