RSB11优异等位变异RSB11-R及其在改良水稻纹枯病抗性中的应用
Genome-wide association analysis was used to identify the superior RSB11-R allelic variant of RSB11. A recombinant vector was constructed to regulate RSB11 protein expression, which solved the problem of lack of resistance to rice sheath blight and achieved effective regulation of rice sheath blight resistance and reduction of yield loss.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- YANGZHOU UNIV
- Filing Date
- 2022-10-18
- Publication Date
- 2026-07-17
AI Technical Summary
Currently, there is a lack of effective resistance gene resources for rice sheath blight. Traditional map-based cloning methods are unable to successfully clone sheath blight-resistant QTLs. The application value of GWAS technology in breeding has not been fully realized, and existing sheath blight-resistant genes are far from meeting the needs in breeding practice.
Genome-wide association analysis (GWAS) was used to identify the superior RSB11 allelic variant RSB11-R. By constructing a recombinant expression vector containing the RSB11 gene, the expression level and activity of RSB11 protein were regulated to enhance or weaken the resistance of rice to sheath blight. Combined with CRISPR/Cas9 technology for gene editing, the regulation of resistance to sheath blight was achieved.
This study enhances or weakens rice's resistance to sheath blight, reduces yield loss, provides important molecular breeding resources for disease resistance, and significantly improves rice's resistance to sheath blight and yield stability.
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