用于混合生物处理系统中的流体的系统、方法和设备
By providing kits containing components such as stopcock valve manifolds, separation chambers, mixing bags, and magnetic cell separation holders, combined with magnetic field generators and bioreactor containers, the high cost and inflexibility of CAR-T cell therapy manufacturing systems are addressed, enabling automated and safe cell processing procedures.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- GLOBAL LIFE SCIENCES SOLUTIONS USA LLC
- Filing Date
- 2021-12-14
- Publication Date
- 2026-07-17
AI Technical Summary
Existing CAR-T cell therapy manufacturing systems suffer from high costs, inflexibility, and workflow bottlenecks, particularly due to increased time and contamination risks caused by extensive manual operations and complex steps.
A kit including a stopcock valve manifold, separation chamber, mixing bag, magnetic cell separation holder, and cell processing bag is provided, which, combined with a magnetic field generator and a bioreactor container, enables an automated, functionally closed cell processing flow, including magnetic cell separation, activation, genetic modification, and amplification steps.
It improves the automation level of the manufacturing process, reduces the cost and pollution risk of manual operation, enhances the flexibility and adaptability of the system, and ensures the safety and consistency of the process.
Smart Images
Figure CN116583344B_ABST