一种提高离子迁移谱检测灵敏度的离子门控制方法
By periodically controlling the voltage of the BNG metal wire to switch the position of the ion clearing zone, the problem of ion loss during BNG gate closing is solved, achieving highly sensitive detection of ion mobility spectrometry, avoiding incomplete gate closing and ion flow leakage, and making it highly applicable.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- DALIAN INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES
- Filing Date
- 2022-12-02
- Publication Date
- 2026-07-17
AI Technical Summary
In existing ion mobility spectrometry detection, ion loss is caused by the ion clearing region generated when the Bradbury-Nielsen type ion gate (BNG) is closed, which reduces the detection sensitivity. Furthermore, existing improved methods suffer from incomplete shut-off or require complex high-voltage power supplies.
By periodically and synchronously controlling the voltage applied to the two sets of metal wires in the BNG, the position of the ion clearing region is switched to eliminate the influence of the ion clearing region on detection. A gradient voltage distribution is formed by using a ring electrode and a voltage divider resistor chain to achieve high-sensitivity detection of the ion gate.
It effectively eliminates ion loss caused by the ion clearing zone, achieves non-discriminatory and highly sensitive detection of ions with different mobility, avoids incomplete gate closing and ion flow leakage, and has low requirements for high voltage power supply and strong applicability.
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Figure CN116598185B_ABST