一种甘草酸稳定的Pickering中低内相凝胶乳液及其制备方法和应用
By combining glycyrrhizic acid with plant essential oils to form nanofiber particles, a glycyrrhizic acid-stabilized Pickering medium-low internal phase gel emulsion was prepared, which solved the problems of insufficient stability and antibacterial properties of traditional dressings in the wound healing of diabetic patients, and achieved effective repair of wounds in diabetic patients.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- WENZHOU INST UNIV OF CHINESE ACAD OF SCI
- Filing Date
- 2023-05-18
- Publication Date
- 2026-07-17
AI Technical Summary
In the existing technology, traditional wound dressings are not effective in healing chronic wounds of diabetic patients, synthetic dressings are expensive and have poor stability, and hydrogel dressings are prone to damaging the skin and have limited application range, making it difficult to meet the high requirements of diabetic patients.
By using a glycyrrhizic acid-stabilized Pickering low-internal-phase gel emulsion, glycyrrhizic acid small molecules are self-assembled to form nanofiber particles, which are then combined with plant essential oils to prepare a stable gel emulsion that can be formed without a high internal phase. This emulsion has antibacterial, anti-inflammatory, and healing-promoting properties.
This gel emulsion exhibits good stability and antibacterial properties in wound healing in diabetic patients. It can slowly release oil phase solvents, providing effective wound repair and is suitable for the treatment of chronic wounds in diabetic patients.
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Figure CN116606452B_ABST